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The map label for this gene is stcD [H]

Identifier: 121610969

GI number: 121610969

Start: 4443569

End: 4445629

Strand: Direct

Name: stcD [H]

Synonym: Veis_4053

Alternate gene names: 121610969

Gene position: 4443569-4445629 (Clockwise)

Preceding gene: 121610968

Following gene: 121610970

Centisome position: 79.82

GC content: 67.93

Gene sequence:

>2061_bases
ATGCAGTACCCGCATCTGTTTGAGCCGATCCGCCTGAACCAGGTGCTGCTGCGCAACCGCATCGTCAGCACCGCCCATGC
CGAGGTCTATGGCCAAGGCGGCGCGCCGAGCGCGCGCTACATCCGCTACTACGAAGAAAAGGCCCGGGGCGGCCTGGGCC
TGGCGATTTGCGGCGGCTCCAGCCCGGTATCGCGCGACAGCCCCTGGTCGTGGTGGAATTCCATCAATCTGGCGCGCAAC
CCGGTGATCGAGCCGCTGGCCCGGCTGGCCGACACCATGCACCGGCATGGCGCCAAACTGATGATACAAGCCACCCATAT
GGGGCGGCGCAACGCCTGGAACGGCTTTGACTGGCCGCACCTGGTCAGCCCCTCGGGCATCCGCGAGCCGGTGCACCGGG
GCAACGCCAAAACCATAGAGATCGAGGACATCCGGCGCATCGTGGCCGACTTCGGCCGGGCCGCCAGGCGCGTCAAGGAC
GCCGGGCTCGACGGCATCGAGATCTCCGCCGCGCACCAGCATCTGATCGACCAGTTCTGGAGCCCGCGCGTCAACCACCG
CAGCGACGAGTACGGCGGCAGCCTGGCCAACCGCCTGCGCTTCGGCATCGAGGTGCTGCAAGCCGTGCGCGAGCAGGTCG
GCGCCGACTTTTGCGTCGGCCTGCGCGTCTGCGGCGATGAGTTCCACGAAGATGGCATCAACCACGAGATGGCCAAAGAA
ATCGCCCAGGCCATGTCCGAAAGCGGCCTGATCGATTTCCTGAGCGTGGCCGGCTCCGGCGCCGACACCCACAACACGCT
GGCCAACTGCATGCCGCCGATGGCCCTGCCGCCCGAGCCTTTCGTGCATCTGGCCGCCGGCATCAAGTCGGTGTCCCGGG
TGCCGGTGATGCACGCGCAAGGCATCCGCGACCCGGGGCAGGCCGAGCGCATTCTGGCCGCCGGCATGGTCGATCTGGTG
GGCATGACGCGCGCGCAGATCGCCGACCCGCATATGGTCGGCAAAATCCGCGACGGCCGCCTGGACCAAATCAAGCAATG
CGTCGGCGCCAATTACTGTATCGACCGGCAATACCAGGGCCTGGACGTGCTGTGCCTGCAAAACGCCGCCACCGGCCGTG
AAGAAATCATGCCGCACCTGATCGGCAAGAGCGCCGGGCGCCGCCGCAAGGTGGTGGTGGTCGGCGCCGGGCCGGCGGGC
CTGGAAGCCGCGCGCGTGGCGCGCGAGCGCGGGCACGAGGTGCTGCTGTTCGAGCAAGCGCCGGTGGTCGGCGGTCAGGT
GAATCTGGCCGCCAAGCCGCCGCAGCGCGAGCAGATGGCCGGCATCATCCGCTGGTTCGACATGGAAACCCGGCGCCTGG
GCGTGCAGCGGCGCCTGGGCGTGGCGGCCGACCAGGCGCTGATCCTGGCCGAAGCGCCCGACATCGTGGTGCTGGCCACC
GGCGGCCTGCCGAACATGGCGCAGACGCCGGCCTGGGGCGCCGCGCAGGGGCTGTGCGTGAGCAGTTGGGACATCCTGTC
GGGCGCCGTCGCGCCCGGCGACAACGTGCTGGTGTACGACAGCATCAGCGCCCATGCCGGCACCGGCGTGGCCGACTTCA
TTGCCGCGCGCGGCAAGCAGGTGGAGATCGTGACGCCCGACGTGAAAGTCGCCGACGACGTGGGCGGCACCACCTTCCCG
ATCTTCTACCGCCAGCTCTACGCCCACGGCGTGATCCTGACGCCGAACCACTGGCTGCACCAGATCTACCGTGAAGGCGA
GCAGCTGATCGCGGTGCTGAAAAACGAATACACCGAGGCGCTGCAAGAACGCGCGGTCGACCAGGTGGTGGTGGAAAACG
GCATCCGGCCGAACGACAGCCTGTACTGGCAGCTCAAGCCGCTATCGCTCAACCAGGGGCAGACCGACATCGACGCGCTG
TATGACGCGCTGCCGCAACCGGATTTGCAGCGGCCCACCGGCGACGGCCAGTTCCTGCTCTACCGCATCGGCGACTGCGT
CTCGATGCACGACATCCACGGCGCCATCTACGACGCGCTGCGGCTGTGCAAGGATTTTTGA

Upstream 100 bases:

>100_bases
CGATGCGCCGCGCAAGCGCCTGCCGCAGACGCTGCCGCAGCAGACGCCGCGCCGCGCGATTGCATCTTCGACGTGCACCC
ACTGGAAGAAGGGCCGCGCC

Downstream 100 bases:

>100_bases
AATGCTGCCGCAACTGGTGCGCATCCTGTTCTGGCTGGCGCTGCTGACCTTGGCCTGGGGCCTGGCGCGGCGCGCGCTGC
TCTGGCGCACGGGGCGCGGC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: trans-transtetradehydroacyl-CoA; NADPH [C]

Alternate protein names: Stachydrine utilization protein stcD [H]

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MQYPHLFEPIRLNQVLLRNRIVSTAHAEVYGQGGAPSARYIRYYEEKARGGLGLAICGGSSPVSRDSPWSWWNSINLARN
PVIEPLARLADTMHRHGAKLMIQATHMGRRNAWNGFDWPHLVSPSGIREPVHRGNAKTIEIEDIRRIVADFGRAARRVKD
AGLDGIEISAAHQHLIDQFWSPRVNHRSDEYGGSLANRLRFGIEVLQAVREQVGADFCVGLRVCGDEFHEDGINHEMAKE
IAQAMSESGLIDFLSVAGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVSRVPVMHAQGIRDPGQAERILAAGMVDLV
GMTRAQIADPHMVGKIRDGRLDQIKQCVGANYCIDRQYQGLDVLCLQNAATGREEIMPHLIGKSAGRRRKVVVVGAGPAG
LEAARVARERGHEVLLFEQAPVVGGQVNLAAKPPQREQMAGIIRWFDMETRRLGVQRRLGVAADQALILAEAPDIVVLAT
GGLPNMAQTPAWGAAQGLCVSSWDILSGAVAPGDNVLVYDSISAHAGTGVADFIAARGKQVEIVTPDVKVADDVGGTTFP
IFYRQLYAHGVILTPNHWLHQIYREGEQLIAVLKNEYTEALQERAVDQVVVENGIRPNDSLYWQLKPLSLNQGQTDIDAL
YDALPQPDLQRPTGDGQFLLYRIGDCVSMHDIHGAIYDALRLCKDF

Sequences:

>Translated_686_residues
MQYPHLFEPIRLNQVLLRNRIVSTAHAEVYGQGGAPSARYIRYYEEKARGGLGLAICGGSSPVSRDSPWSWWNSINLARN
PVIEPLARLADTMHRHGAKLMIQATHMGRRNAWNGFDWPHLVSPSGIREPVHRGNAKTIEIEDIRRIVADFGRAARRVKD
AGLDGIEISAAHQHLIDQFWSPRVNHRSDEYGGSLANRLRFGIEVLQAVREQVGADFCVGLRVCGDEFHEDGINHEMAKE
IAQAMSESGLIDFLSVAGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVSRVPVMHAQGIRDPGQAERILAAGMVDLV
GMTRAQIADPHMVGKIRDGRLDQIKQCVGANYCIDRQYQGLDVLCLQNAATGREEIMPHLIGKSAGRRRKVVVVGAGPAG
LEAARVARERGHEVLLFEQAPVVGGQVNLAAKPPQREQMAGIIRWFDMETRRLGVQRRLGVAADQALILAEAPDIVVLAT
GGLPNMAQTPAWGAAQGLCVSSWDILSGAVAPGDNVLVYDSISAHAGTGVADFIAARGKQVEIVTPDVKVADDVGGTTFP
IFYRQLYAHGVILTPNHWLHQIYREGEQLIAVLKNEYTEALQERAVDQVVVENGIRPNDSLYWQLKPLSLNQGQTDIDAL
YDALPQPDLQRPTGDGQFLLYRIGDCVSMHDIHGAIYDALRLCKDF
>Mature_686_residues
MQYPHLFEPIRLNQVLLRNRIVSTAHAEVYGQGGAPSARYIRYYEEKARGGLGLAICGGSSPVSRDSPWSWWNSINLARN
PVIEPLARLADTMHRHGAKLMIQATHMGRRNAWNGFDWPHLVSPSGIREPVHRGNAKTIEIEDIRRIVADFGRAARRVKD
AGLDGIEISAAHQHLIDQFWSPRVNHRSDEYGGSLANRLRFGIEVLQAVREQVGADFCVGLRVCGDEFHEDGINHEMAKE
IAQAMSESGLIDFLSVAGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVSRVPVMHAQGIRDPGQAERILAAGMVDLV
GMTRAQIADPHMVGKIRDGRLDQIKQCVGANYCIDRQYQGLDVLCLQNAATGREEIMPHLIGKSAGRRRKVVVVGAGPAG
LEAARVARERGHEVLLFEQAPVVGGQVNLAAKPPQREQMAGIIRWFDMETRRLGVQRRLGVAADQALILAEAPDIVVLAT
GGLPNMAQTPAWGAAQGLCVSSWDILSGAVAPGDNVLVYDSISAHAGTGVADFIAARGKQVEIVTPDVKVADDVGGTTFP
IFYRQLYAHGVILTPNHWLHQIYREGEQLIAVLKNEYTEALQERAVDQVVVENGIRPNDSLYWQLKPLSLNQGQTDIDAL
YDALPQPDLQRPTGDGQFLLYRIGDCVSMHDIHGAIYDALRLCKDF

Specific function: Possible NADH-dependent oxidase, functions as a demethylase that converts N-methylproline to proline [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=679, Percent_Identity=30.3387334315169, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI1787939, Length=361, Percent_Identity=25.7617728531856, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559802, Length=347, Percent_Identity=28.8184438040346, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17559804, Length=266, Percent_Identity=30.8270676691729, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=341, Percent_Identity=25.8064516129032, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=266, Percent_Identity=29.6992481203008, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=372, Percent_Identity=23.3870967741935, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI72001454, Length=264, Percent_Identity=28.7878787878788, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=250, Percent_Identity=29.6, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=240, Percent_Identity=27.5, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=87, Percent_Identity=41.3793103448276, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: 1.3.1.34 [C]

Molecular weight: Translated: 75127; Mature: 75127

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYPHLFEPIRLNQVLLRNRIVSTAHAEVYGQGGAPSARYIRYYEEKARGGLGLAICGGS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCCEEEEECCC
SPVSRDSPWSWWNSINLARNPVIEPLARLADTMHRHGAKLMIQATHMGRRNAWNGFDWPH
CCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCC
LVSPSGIREPVHRGNAKTIEIEDIRRIVADFGRAARRVKDAGLDGIEISAAHQHLIDQFW
CCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHC
SPRVNHRSDEYGGSLANRLRFGIEVLQAVREQVGADFCVGLRVCGDEFHEDGINHEMAKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHH
IAQAMSESGLIDFLSVAGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVSRVPVMHAQ
HHHHHHHCCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHC
GIRDPGQAERILAAGMVDLVGMTRAQIADPHMVGKIRDGRLDQIKQCVGANYCIDRQYQG
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHCCCCEECCCCCC
LDVLCLQNAATGREEIMPHLIGKSAGRRRKVVVVGAGPAGLEAARVARERGHEVLLFEQA
CEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECC
PVVGGQVNLAAKPPQREQMAGIIRWFDMETRRLGVQRRLGVAADQALILAEAPDIVVLAT
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEC
GGLPNMAQTPAWGAAQGLCVSSWDILSGAVAPGDNVLVYDSISAHAGTGVADFIAARGKQ
CCCCCCCCCCCCCCCCCCEEECHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCE
VEIVTPDVKVADDVGGTTFPIFYRQLYAHGVILTPNHWLHQIYREGEQLIAVLKNEYTEA
EEEECCCCEEHHCCCCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LQERAVDQVVVENGIRPNDSLYWQLKPLSLNQGQTDIDALYDALPQPDLQRPTGDGQFLL
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEE
YRIGDCVSMHDIHGAIYDALRLCKDF
EECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQYPHLFEPIRLNQVLLRNRIVSTAHAEVYGQGGAPSARYIRYYEEKARGGLGLAICGGS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCCEEEEECCC
SPVSRDSPWSWWNSINLARNPVIEPLARLADTMHRHGAKLMIQATHMGRRNAWNGFDWPH
CCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCC
LVSPSGIREPVHRGNAKTIEIEDIRRIVADFGRAARRVKDAGLDGIEISAAHQHLIDQFW
CCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHC
SPRVNHRSDEYGGSLANRLRFGIEVLQAVREQVGADFCVGLRVCGDEFHEDGINHEMAKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHH
IAQAMSESGLIDFLSVAGSGADTHNTLANCMPPMALPPEPFVHLAAGIKSVSRVPVMHAQ
HHHHHHHCCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHC
GIRDPGQAERILAAGMVDLVGMTRAQIADPHMVGKIRDGRLDQIKQCVGANYCIDRQYQG
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHCCCCEECCCCCC
LDVLCLQNAATGREEIMPHLIGKSAGRRRKVVVVGAGPAGLEAARVARERGHEVLLFEQA
CEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECC
PVVGGQVNLAAKPPQREQMAGIIRWFDMETRRLGVQRRLGVAADQALILAEAPDIVVLAT
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEC
GGLPNMAQTPAWGAAQGLCVSSWDILSGAVAPGDNVLVYDSISAHAGTGVADFIAARGKQ
CCCCCCCCCCCCCCCCCCEEECHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCE
VEIVTPDVKVADDVGGTTFPIFYRQLYAHGVILTPNHWLHQIYREGEQLIAVLKNEYTEA
EEEECCCCEEHHCCCCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LQERAVDQVVVENGIRPNDSLYWQLKPLSLNQGQTDIDALYDALPQPDLQRPTGDGQFLL
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEE
YRIGDCVSMHDIHGAIYDALRLCKDF
EECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD. [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: transDidehydroacyl-CoA; NADP+ [C]

Specific reaction: transDidehydroacyl-CoA + NADP+ =trans-transtetradehydroacyl-CoA + NADPH [C]

General reaction: Redox reaction [C]

Inhibitor: Iodoacetic acid; N-Ethyl maleimide [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9758825; 11481431 [H]