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The map label for this gene is paaK [H]

Identifier: 121610862

GI number: 121610862

Start: 4329429

End: 4330748

Strand: Direct

Name: paaK [H]

Synonym: Veis_3944

Alternate gene names: 121610862

Gene position: 4329429-4330748 (Clockwise)

Preceding gene: 121610861

Following gene: 121610863

Centisome position: 77.77

GC content: 67.95

Gene sequence:

>1320_bases
ATGGCCGTGCGTCAACCCGCTCCCGCTGCCCTGGATCCGATGGAAAGCGCCAGCCGCGACGCCATCGAGGCGCTGCAATT
GCAGCGTCTGCGCTGGACGCTGCAACATGCCTACGACAACGTGGCGCATTACCGCCGCGCGTTTGACGCCCGGGGGGTGC
TCCCCGGCGACCTCAAGCATCTGTCCGATCTGGCCGGGTTTCCGTTCACGGTCAAGCAGGACCTGCGCGACAACTACCCC
TTTGGCATGTTCGCCGTGCCGCGCGCGCAGTTGCTGCGCCTGCACGCCTCGTCGGGCACCACGGGCAAGCCCACGGTGGT
GGGCTACACGCGCCAGGACATCGACCACTGGGCCGACCTGGTGGCGCGCTCGATCCGCGCCGCCGGCGGGCGCCCGGGCG
ACCTGGTGCATGTGGCCTACGGCTACGGTCTGTTCACGGGCGGGCTGGGCGCGCATTACGGCGCCGAGCGCGCCGGCTGC
ACCGTGGTGCCGATGTCGGGCGGACAGACCGAAAAGCAGGTGCAACTGATCCACGACCTGCAACCCCGCATCATCATGGT
CACGCCCTCGTACATGCAGATCATCACCGAGGAGTTCCTGCGCCAGGGGCTGGATCCGCGTGCCAGTTCGTTGCAGATCG
GCATTTTTGGCGCCGAGCCTTGGACCGAGGCCATGCGCCGCGAGATCGAGGCCGGCGCCGGGATCGACGCGCTGGACATC
TATGGCCTGTCGGAGGTGATGGGCCCGGGCGTTGCCAGCGAATGCGTCGAGAGCAAGGACGGCCCCGTGGTCTGGGAAGA
CCATTTCTACCCCGAGATCATCGACCCCGACAGCGGCCAAGTGCTGCCCGACGGCCAGCCAGGCGAGCTGGTGCTCACCT
CGCTGAGCAAGCAGGCGTTGCCGATGATCCGCTACCGCACGCGCGATCTGACGCGGCTGCTGCCGCCGACATCGCGGTCG
ATGCGGCGCATCGGCAAGATCGTCGGCCGCTCGGACGACATGCTGATCATCCGTGGCGTGAACCTGTTTCCCACGCAGAT
CGAAGAGATCGTGCTGCACAGCGGCAGGCTGTCGGGGCACTACCAGATTCTGGTGACGCGCGCTGGCCATCTGGACCAGG
TGACCGTGCGCTGCGAGTTGCAGCCGGGCCTGTCTGCGGACCTGCCTGCCGGCGAGCGCCAGGCGCTGGCCGATGCGGTG
CAGCAGCGCATCAAAACCCTGGTGGGCATCAGTTGCCAGGTGCAGGTGCTGGCTGCCAACGCCATCGAGCGCACGCTGGT
GGGCAAGGCCCGGCGCGTCATCGACCAGCGCCCGCGTTGA

Upstream 100 bases:

>100_bases
GTTCGTACTGCATGCCGGGCCGGCCGACCGTGCCGCTGGACGCCGGCTGATGGCTGACGGCCGACGAATGACGATTCGCT
GAACGACAGGAGACTGCGCC

Downstream 100 bases:

>100_bases
TGGATCGATGCCCGATACGAAAGGCTCTCCGATGTACACCCAAGCGATGGACCTGATGGATCAGATGGCGCCGGGCGATG
CCGGCGACGCCCGGCAGATG

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MAVRQPAPAALDPMESASRDAIEALQLQRLRWTLQHAYDNVAHYRRAFDARGVLPGDLKHLSDLAGFPFTVKQDLRDNYP
FGMFAVPRAQLLRLHASSGTTGKPTVVGYTRQDIDHWADLVARSIRAAGGRPGDLVHVAYGYGLFTGGLGAHYGAERAGC
TVVPMSGGQTEKQVQLIHDLQPRIIMVTPSYMQIITEEFLRQGLDPRASSLQIGIFGAEPWTEAMRREIEAGAGIDALDI
YGLSEVMGPGVASECVESKDGPVVWEDHFYPEIIDPDSGQVLPDGQPGELVLTSLSKQALPMIRYRTRDLTRLLPPTSRS
MRRIGKIVGRSDDMLIIRGVNLFPTQIEEIVLHSGRLSGHYQILVTRAGHLDQVTVRCELQPGLSADLPAGERQALADAV
QQRIKTLVGISCQVQVLAANAIERTLVGKARRVIDQRPR

Sequences:

>Translated_439_residues
MAVRQPAPAALDPMESASRDAIEALQLQRLRWTLQHAYDNVAHYRRAFDARGVLPGDLKHLSDLAGFPFTVKQDLRDNYP
FGMFAVPRAQLLRLHASSGTTGKPTVVGYTRQDIDHWADLVARSIRAAGGRPGDLVHVAYGYGLFTGGLGAHYGAERAGC
TVVPMSGGQTEKQVQLIHDLQPRIIMVTPSYMQIITEEFLRQGLDPRASSLQIGIFGAEPWTEAMRREIEAGAGIDALDI
YGLSEVMGPGVASECVESKDGPVVWEDHFYPEIIDPDSGQVLPDGQPGELVLTSLSKQALPMIRYRTRDLTRLLPPTSRS
MRRIGKIVGRSDDMLIIRGVNLFPTQIEEIVLHSGRLSGHYQILVTRAGHLDQVTVRCELQPGLSADLPAGERQALADAV
QQRIKTLVGISCQVQVLAANAIERTLVGKARRVIDQRPR
>Mature_438_residues
AVRQPAPAALDPMESASRDAIEALQLQRLRWTLQHAYDNVAHYRRAFDARGVLPGDLKHLSDLAGFPFTVKQDLRDNYPF
GMFAVPRAQLLRLHASSGTTGKPTVVGYTRQDIDHWADLVARSIRAAGGRPGDLVHVAYGYGLFTGGLGAHYGAERAGCT
VVPMSGGQTEKQVQLIHDLQPRIIMVTPSYMQIITEEFLRQGLDPRASSLQIGIFGAEPWTEAMRREIEAGAGIDALDIY
GLSEVMGPGVASECVESKDGPVVWEDHFYPEIIDPDSGQVLPDGQPGELVLTSLSKQALPMIRYRTRDLTRLLPPTSRSM
RRIGKIVGRSDDMLIIRGVNLFPTQIEEIVLHSGRLSGHYQILVTRAGHLDQVTVRCELQPGLSADLPAGERQALADAVQ
QRIKTLVGISCQVQVLAANAIERTLVGKARRVIDQRPR

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=428, Percent_Identity=63.785046728972, Blast_Score=559, Evalue=1e-160,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48210; Mature: 48079

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRQPAPAALDPMESASRDAIEALQLQRLRWTLQHAYDNVAHYRRAFDARGVLPGDLKH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LSDLAGFPFTVKQDLRDNYPFGMFAVPRAQLLRLHASSGTTGKPTVVGYTRQDIDHWADL
HHHHCCCCCEEHHHHHCCCCCCEEECCHHHHHEEECCCCCCCCCEEEECHHHHHHHHHHH
VARSIRAAGGRPGDLVHVAYGYGLFTGGLGAHYGAERAGCTVVPMSGGQTEKQVQLIHDL
HHHHHHHCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCC
QPRIIMVTPSYMQIITEEFLRQGLDPRASSLQIGIFGAEPWTEAMRREIEAGAGIDALDI
CCCEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHH
YGLSEVMGPGVASECVESKDGPVVWEDHFYPEIIDPDSGQVLPDGQPGELVLTSLSKQAL
CCHHHHHCCCHHHHHHCCCCCCEEECCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHH
PMIRYRTRDLTRLLPPTSRSMRRIGKIVGRSDDMLIIRGVNLFPTQIEEIVLHSGRLSGH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCE
YQILVTRAGHLDQVTVRCELQPGLSADLPAGERQALADAVQQRIKTLVGISCQVQVLAAN
EEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHH
AIERTLVGKARRVIDQRPR
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVRQPAPAALDPMESASRDAIEALQLQRLRWTLQHAYDNVAHYRRAFDARGVLPGDLKH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LSDLAGFPFTVKQDLRDNYPFGMFAVPRAQLLRLHASSGTTGKPTVVGYTRQDIDHWADL
HHHHCCCCCEEHHHHHCCCCCCEEECCHHHHHEEECCCCCCCCCEEEECHHHHHHHHHHH
VARSIRAAGGRPGDLVHVAYGYGLFTGGLGAHYGAERAGCTVVPMSGGQTEKQVQLIHDL
HHHHHHHCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCC
QPRIIMVTPSYMQIITEEFLRQGLDPRASSLQIGIFGAEPWTEAMRREIEAGAGIDALDI
CCCEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHH
YGLSEVMGPGVASECVESKDGPVVWEDHFYPEIIDPDSGQVLPDGQPGELVLTSLSKQAL
CCHHHHHCCCHHHHHHCCCCCCEEECCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHH
PMIRYRTRDLTRLLPPTSRSMRRIGKIVGRSDDMLIIRGVNLFPTQIEEIVLHSGRLSGH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCE
YQILVTRAGHLDQVTVRCELQPGLSADLPAGERQALADAVQQRIKTLVGISCQVQVLAAN
EEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHH
AIERTLVGKARRVIDQRPR
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]