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The map label for this gene is paaG [H]

Identifier: 121610860

GI number: 121610860

Start: 4328079

End: 4328912

Strand: Direct

Name: paaG [H]

Synonym: Veis_3942

Alternate gene names: 121610860

Gene position: 4328079-4328912 (Clockwise)

Preceding gene: 121610859

Following gene: 121610861

Centisome position: 77.75

GC content: 71.46

Gene sequence:

>834_bases
ATGTCTGAACCCCTTGTCTTGGTGACGCAATCGGGTGCCGTGCAAACGCTGGCGCTGAACCGGCCGGCCGCGCTGAACAG
CTTGACCGCCGCGTTGCACGCGCAGTTGCTGGCCGCGCTGGAGGCCACCGCTGCCGCGTGCGACGTGCGCTGCGTGGTCA
TCACGGGCATGGGGCGGGCGTTTTGCGCCGGCCAGGACCTGAATGACATCGCCGCCGCGCCTGCGTCCGGTTCGGGCGAT
CCGGCGCCCGCGCCCGGTTCGGCGGGCGCTCAGGCCCAGGACTTGGGCCGCGTGATCGAGACCCTGTACCGGCCGCTGTG
TCTGCGCATCCGCAGCATGCCCGTTCCGGTGCTGGCAGCGGTCAACGGTGTGGCCGCCGGTGCCGGTGCCTGCCTGGCTC
TGGGCTGCGATCTGGTGCTGGCGGCGCGTTCGGCCAGTTTCATCATGGCTTTCAGCAAAATCGGGCTGCTGCCCGATACC
GGCGGAACCTGGCTGCTGCCGCGCCTGGTGGGGCGCGCGCAGGCTCTGGGGCTGGCCTTGCTGGGCGACAAACTGCCTGC
GCCCGAGGCCGAGCGTCGCGGCCTGATCTGGCGCTGCGTGGACGACGCCAGTTTGCCGGACGAGGCGCTGGCCCTGGCGC
AGCGCCTGGCCGCCATGCCCGTCAAGGCGCTGGTGGCCACGCGCCAGGCCATGGATGCTGCGGCGCAACTGGACTACGGC
CAGGCGCTGGCGCAGGAAGCGGCCATGCAGCAAACGCTGGGCGCCGGTGCCGATTACCGCGAAGGCGTCGCGGCCTTCGC
CGGCAAGCGCGCCCCTCGTTTCACCGAGCGTTGA

Upstream 100 bases:

>100_bases
CTACCGCACGGTCGGTCAATGATGTTCGTGATCGATCGATGCAGGACTTCCCCTTCCTGATGGTGATTGATGGTGATGGG
CAGCAGCAGCAGGAGCATTC

Downstream 100 bases:

>100_bases
GCAGACCATGCCTTGCTCCACCGACAGACCCAACCCCCAGGCCGTGGCCGACCATGTGCGCAGCGGCATGCTGGCCAAGG
ACCGCGCCACCCGGGGCCTG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSEPLVLVTQSGAVQTLALNRPAALNSLTAALHAQLLAALEATAAACDVRCVVITGMGRAFCAGQDLNDIAAAPASGSGD
PAPAPGSAGAQAQDLGRVIETLYRPLCLRIRSMPVPVLAAVNGVAAGAGACLALGCDLVLAARSASFIMAFSKIGLLPDT
GGTWLLPRLVGRAQALGLALLGDKLPAPEAERRGLIWRCVDDASLPDEALALAQRLAAMPVKALVATRQAMDAAAQLDYG
QALAQEAAMQQTLGAGADYREGVAAFAGKRAPRFTER

Sequences:

>Translated_277_residues
MSEPLVLVTQSGAVQTLALNRPAALNSLTAALHAQLLAALEATAAACDVRCVVITGMGRAFCAGQDLNDIAAAPASGSGD
PAPAPGSAGAQAQDLGRVIETLYRPLCLRIRSMPVPVLAAVNGVAAGAGACLALGCDLVLAARSASFIMAFSKIGLLPDT
GGTWLLPRLVGRAQALGLALLGDKLPAPEAERRGLIWRCVDDASLPDEALALAQRLAAMPVKALVATRQAMDAAAQLDYG
QALAQEAAMQQTLGAGADYREGVAAFAGKRAPRFTER
>Mature_276_residues
SEPLVLVTQSGAVQTLALNRPAALNSLTAALHAQLLAALEATAAACDVRCVVITGMGRAFCAGQDLNDIAAAPASGSGDP
APAPGSAGAQAQDLGRVIETLYRPLCLRIRSMPVPVLAAVNGVAAGAGACLALGCDLVLAARSASFIMAFSKIGLLPDTG
GTWLLPRLVGRAQALGLALLGDKLPAPEAERRGLIWRCVDDASLPDEALALAQRLAAMPVKALVATRQAMDAAAQLDYGQ
ALAQEAAMQQTLGAGADYREGVAAFAGKRAPRFTER

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=268, Percent_Identity=27.9850746268657, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI31542718, Length=268, Percent_Identity=27.2388059701493, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI45643119, Length=229, Percent_Identity=26.6375545851528, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI260275230, Length=229, Percent_Identity=26.6375545851528, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI260274832, Length=269, Percent_Identity=24.5353159851301, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI70995211, Length=211, Percent_Identity=30.3317535545024, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4502327, Length=275, Percent_Identity=30.1818181818182, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI37594469, Length=251, Percent_Identity=27.4900398406374, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI37594471, Length=251, Percent_Identity=27.4900398406374, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI68989263, Length=218, Percent_Identity=27.9816513761468, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI20127408, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI157694516, Length=261, Percent_Identity=21.8390804597701, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI213417737, Length=261, Percent_Identity=21.8390804597701, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787660, Length=271, Percent_Identity=49.8154981549816, Blast_Score=221, Evalue=3e-59,
Organism=Escherichia coli, GI1787659, Length=277, Percent_Identity=35.7400722021661, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI221142681, Length=282, Percent_Identity=30.8510638297872, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788597, Length=277, Percent_Identity=26.3537906137184, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082183, Length=280, Percent_Identity=22.5, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788682, Length=219, Percent_Identity=27.3972602739726, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=274, Percent_Identity=32.8467153284672, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17554946, Length=280, Percent_Identity=30, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540306, Length=271, Percent_Identity=30.6273062730627, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560910, Length=272, Percent_Identity=26.1029411764706, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=239, Percent_Identity=28.0334728033473, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17535521, Length=222, Percent_Identity=26.5765765765766, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=232, Percent_Identity=28.0172413793103, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25144157, Length=203, Percent_Identity=29.5566502463054, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25144160, Length=203, Percent_Identity=29.5566502463054, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=258, Percent_Identity=25.968992248062, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=236, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129971, Length=264, Percent_Identity=29.1666666666667, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24653477, Length=264, Percent_Identity=29.1666666666667, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19922422, Length=281, Percent_Identity=27.0462633451957, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653139, Length=267, Percent_Identity=29.5880149812734, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654903, Length=220, Percent_Identity=26.8181818181818, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19920382, Length=255, Percent_Identity=26.2745098039216, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571730, Length=209, Percent_Identity=28.2296650717703, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571729, Length=209, Percent_Identity=28.2296650717703, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650670, Length=267, Percent_Identity=28.0898876404494, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357171, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28245; Mature: 28114

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLVLVTQSGAVQTLALNRPAALNSLTAALHAQLLAALEATAAACDVRCVVITGMGRA
CCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCH
FCAGQDLNDIAAAPASGSGDPAPAPGSAGAQAQDLGRVIETLYRPLCLRIRSMPVPVLAA
HCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VNGVAAGAGACLALGCDLVLAARSASFIMAFSKIGLLPDTGGTWLLPRLVGRAQALGLAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LGDKLPAPEAERRGLIWRCVDDASLPDEALALAQRLAAMPVKALVATRQAMDAAAQLDYG
HCCCCCCCCHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALAQEAAMQQTLGAGADYREGVAAFAGKRAPRFTER
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SEPLVLVTQSGAVQTLALNRPAALNSLTAALHAQLLAALEATAAACDVRCVVITGMGRA
CCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCH
FCAGQDLNDIAAAPASGSGDPAPAPGSAGAQAQDLGRVIETLYRPLCLRIRSMPVPVLAA
HCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VNGVAAGAGACLALGCDLVLAARSASFIMAFSKIGLLPDTGGTWLLPRLVGRAQALGLAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LGDKLPAPEAERRGLIWRCVDDASLPDEALALAQRLAAMPVKALVATRQAMDAAAQLDYG
HCCCCCCCCHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALAQEAAMQQTLGAGADYREGVAAFAGKRAPRFTER
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]