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The map label for this gene is tauD [H]

Identifier: 121610729

GI number: 121610729

Start: 4202172

End: 4202975

Strand: Direct

Name: tauD [H]

Synonym: Veis_3809

Alternate gene names: 121610729

Gene position: 4202172-4202975 (Clockwise)

Preceding gene: 121610728

Following gene: 121610735

Centisome position: 75.49

GC content: 63.31

Gene sequence:

>804_bases
ATGACAAAGCCCAAAGTGACACCGCTGACCGGTTCCATCGGCGCCAGCGTCGAAGGCATCGATCTGAACAAACCTGTCGA
CGATGCGACATTCGCCGCGCTGCACGACGCCTTCCTCACGCATTGCGTGCTGGTTTACCGTGGCCAGCAGTTGCAGCCTG
CAGCCCAGGTCGAATTCGCCCGCTGCTGGGGCACGCCGTTGAACACCAACCCGCTGATCAAGCACATCGAATCGCACCCC
GAGATCGTGCAAGTGACCAAAATCCCCAAGGCGACCGCATCGACCGAGGCCTGGCACTACGACTCGCCGTACATACCGGT
CCCGCCCAAGATTTCGATCCTTTCGGCCGTGACGGTGCCCCACGGGGGCGACACCATGTGGTGCAACCAGTGCCTGTCTT
ACGACCGGCTGTCGCCGACGATGAAAGGCGCACTGGAGGGCCTGCGCGTGAAATTCGTCGGCTTGCGCCTGGGCCGCATG
ATGGGCGCCGATGCGGCCAGCCTGCCGTCGGCCGTGCATCCGCTGGTGCGCACCCATCCGGAGACCGGCCGCAAGGCGCT
GTATGTCGGCCACCGCGAAACGGCGCAACTCATCGATGGCATGACGGCCGAGGAAAGCCGCCCGCTGCTCGACTTCCTGT
ATCAGCATTCGACGAGCCCGGACAACATCTACCGCCACATGTGGCAGCCAGGCGATGTCGTGATGTGGGACAACCGCTGC
ACCATGCACTACGCCGTTCACGACTATGGCGAAGCCGAGCGGGTGCTCAACCGCATCACCATCGAAGGCGAAACGCCGCA
ATGA

Upstream 100 bases:

>100_bases
TTTGCGCTGGACGACATCCATGCAGCCCATGCCTACATGATGGAGAGTCGGCATTTCGGCAAGATCGTCCTGACCATCGA
TTGAACCGTGAGGAGACGAG

Downstream 100 bases:

>100_bases
AACGCGACCCGATGGCGCGTGATGGGCGCAGGATGGCGCGCCGCGCGCGCATCCCTGCGCCTGGCCGCGCAGCGCCTGAC
GCAATGGCTGCGGACAACTG

Product: taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTKPKVTPLTGSIGASVEGIDLNKPVDDATFAALHDAFLTHCVLVYRGQQLQPAAQVEFARCWGTPLNTNPLIKHIESHP
EIVQVTKIPKATASTEAWHYDSPYIPVPPKISILSAVTVPHGGDTMWCNQCLSYDRLSPTMKGALEGLRVKFVGLRLGRM
MGADAASLPSAVHPLVRTHPETGRKALYVGHRETAQLIDGMTAEESRPLLDFLYQHSTSPDNIYRHMWQPGDVVMWDNRC
TMHYAVHDYGEAERVLNRITIEGETPQ

Sequences:

>Translated_267_residues
MTKPKVTPLTGSIGASVEGIDLNKPVDDATFAALHDAFLTHCVLVYRGQQLQPAAQVEFARCWGTPLNTNPLIKHIESHP
EIVQVTKIPKATASTEAWHYDSPYIPVPPKISILSAVTVPHGGDTMWCNQCLSYDRLSPTMKGALEGLRVKFVGLRLGRM
MGADAASLPSAVHPLVRTHPETGRKALYVGHRETAQLIDGMTAEESRPLLDFLYQHSTSPDNIYRHMWQPGDVVMWDNRC
TMHYAVHDYGEAERVLNRITIEGETPQ
>Mature_266_residues
TKPKVTPLTGSIGASVEGIDLNKPVDDATFAALHDAFLTHCVLVYRGQQLQPAAQVEFARCWGTPLNTNPLIKHIESHPE
IVQVTKIPKATASTEAWHYDSPYIPVPPKISILSAVTVPHGGDTMWCNQCLSYDRLSPTMKGALEGLRVKFVGLRLGRMM
GADAASLPSAVHPLVRTHPETGRKALYVGHRETAQLIDGMTAEESRPLLDFLYQHSTSPDNIYRHMWQPGDVVMWDNRCT
MHYAVHDYGEAERVLNRITIEGETPQ

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=274, Percent_Identity=35.7664233576642, Blast_Score=167, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6322971, Length=281, Percent_Identity=30.9608540925267, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 29629; Mature: 29498

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPKVTPLTGSIGASVEGIDLNKPVDDATFAALHDAFLTHCVLVYRGQQLQPAAQVEFA
CCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RCWGTPLNTNPLIKHIESHPEIVQVTKIPKATASTEAWHYDSPYIPVPPKISILSAVTVP
HHCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCEEEEEEEECC
HGGDTMWCNQCLSYDRLSPTMKGALEGLRVKFVGLRLGRMMGADAASLPSAVHPLVRTHP
CCCCHHHHHHHHCHHHCCHHHHHHHHHHEEEEEHHHHHHHHCCCHHHCCHHHHHHHHCCC
ETGRKALYVGHRETAQLIDGMTAEESRPLLDFLYQHSTSPDNIYRHMWQPGDVVMWDNRC
CCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCE
TMHYAVHDYGEAERVLNRITIEGETPQ
EEEEEECCCCHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
TKPKVTPLTGSIGASVEGIDLNKPVDDATFAALHDAFLTHCVLVYRGQQLQPAAQVEFA
CCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RCWGTPLNTNPLIKHIESHPEIVQVTKIPKATASTEAWHYDSPYIPVPPKISILSAVTVP
HHCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCEEEEEEEECC
HGGDTMWCNQCLSYDRLSPTMKGALEGLRVKFVGLRLGRMMGADAASLPSAVHPLVRTHP
CCCCHHHHHHHHCHHHCCHHHHHHHHHHEEEEEHHHHHHHHCCCHHHCCHHHHHHHHCCC
ETGRKALYVGHRETAQLIDGMTAEESRPLLDFLYQHSTSPDNIYRHMWQPGDVVMWDNRC
CCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCE
TMHYAVHDYGEAERVLNRITIEGETPQ
EEEEEECCCCHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]