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The map label for this gene is map [H]

Identifier: 121610538

GI number: 121610538

Start: 3992811

End: 3993641

Strand: Direct

Name: map [H]

Synonym: Veis_3610

Alternate gene names: 121610538

Gene position: 3992811-3993641 (Clockwise)

Preceding gene: 121610534

Following gene: 121610539

Centisome position: 71.73

GC content: 65.58

Gene sequence:

>831_bases
ATGGATAATCGCGCCATGAGCATCACCATCAAAAGCGCACAGGACATTGCCGGCATGCGCCTGGCGTGTCGCCTGGCTTC
CGAAGTGCTGGACTCGATTGCTGCGCATATACAGCCGGGCATCACCACCCGCGACATCGACCGGATCGGGGCCGAGTGCA
TGGCCCGGCAGGGCACGGTATCGGCCACCGTCGGCTACCAGCCGCCCGGCTATCCGCCCTACCCGGCGTCGCTGTGCACC
TCGGTCAACCATGTGGTCTGCCATGGCATCCCGAACGACAAGCCGCTGAAAAAGGGCGACATCGTCAATGTCGACGTGAC
CGTCATCACCCCCGAGGGCTGGTATGGCGACAGCAGCCGCATGTACCTGATCGGCGAGGCCTCGATCGCCGCCCGGCGCC
TGTGCGCCCTCACCTACGACGCGATGTGGCACGGCATCGTGCAGGTGCGGCCCGGCGCCCATCTGGGCGATGTGGGGCAT
GCGATACAGCAGTTCGCCGAAAGCCAGGGCTGCTCCGTCGTGCGCGAGTTCTGCGGCCACGGCATCGGCAGAAAGTTCCA
TGAAGAGCCTCAGGTGCTGCACTACGGCCGCCCCGGCACGCTGGCCGAGCTCAGGCCCGGCATGGTCTTCACCATCGAGC
CCATGATCAACGCCGGGCGCCGCGAGGTCAAAGAATTCGGCAACGACGGCTGGACCATCGTGACCAAAGACCACAGCCTG
TCGGCACAGTGGGAGCACACCGTGCTGGTCACGCCCACCGGGTATGAGGTGTTGACCCTGTCGGCAGGCTCGCCGCCATT
GCCGAACTTCGTCGCGGCCACTGCGACCTGA

Upstream 100 bases:

>100_bases
GGGTGCCGCGCCCCGGCGTTCGGGCCGTCGGGCCATTGGGCCGTAGGCGGGCGCCGGCGGTGTCCATCGAAGTGCCGGCG
CGGACAGGAACGGGATGGCT

Downstream 100 bases:

>100_bases
GCGCAGTCTATGGCCTCGGCCCGAGCGCAACGACACGACGCCGGTGCGGCACCCAGGCAACCCCGAGCCGACACACCGGA
GCGCATGCGCACCACGACCA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDNRAMSITIKSAQDIAGMRLACRLASEVLDSIAAHIQPGITTRDIDRIGAECMARQGTVSATVGYQPPGYPPYPASLCT
SVNHVVCHGIPNDKPLKKGDIVNVDVTVITPEGWYGDSSRMYLIGEASIAARRLCALTYDAMWHGIVQVRPGAHLGDVGH
AIQQFAESQGCSVVREFCGHGIGRKFHEEPQVLHYGRPGTLAELRPGMVFTIEPMINAGRREVKEFGNDGWTIVTKDHSL
SAQWEHTVLVTPTGYEVLTLSAGSPPLPNFVAATAT

Sequences:

>Translated_276_residues
MDNRAMSITIKSAQDIAGMRLACRLASEVLDSIAAHIQPGITTRDIDRIGAECMARQGTVSATVGYQPPGYPPYPASLCT
SVNHVVCHGIPNDKPLKKGDIVNVDVTVITPEGWYGDSSRMYLIGEASIAARRLCALTYDAMWHGIVQVRPGAHLGDVGH
AIQQFAESQGCSVVREFCGHGIGRKFHEEPQVLHYGRPGTLAELRPGMVFTIEPMINAGRREVKEFGNDGWTIVTKDHSL
SAQWEHTVLVTPTGYEVLTLSAGSPPLPNFVAATAT
>Mature_276_residues
MDNRAMSITIKSAQDIAGMRLACRLASEVLDSIAAHIQPGITTRDIDRIGAECMARQGTVSATVGYQPPGYPPYPASLCT
SVNHVVCHGIPNDKPLKKGDIVNVDVTVITPEGWYGDSSRMYLIGEASIAARRLCALTYDAMWHGIVQVRPGAHLGDVGH
AIQQFAESQGCSVVREFCGHGIGRKFHEEPQVLHYGRPGTLAELRPGMVFTIEPMINAGRREVKEFGNDGWTIVTKDHSL
SAQWEHTVLVTPTGYEVLTLSAGSPPLPNFVAATAT

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=266, Percent_Identity=45.8646616541353, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI40385867, Length=253, Percent_Identity=37.9446640316205, Blast_Score=176, Evalue=2e-44,
Organism=Escherichia coli, GI1786364, Length=257, Percent_Identity=52.9182879377432, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1788728, Length=255, Percent_Identity=27.4509803921569, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996291, Length=260, Percent_Identity=40, Blast_Score=200, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6323273, Length=266, Percent_Identity=40.9774436090226, Blast_Score=201, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21355531, Length=268, Percent_Identity=39.9253731343284, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24583427, Length=259, Percent_Identity=37.0656370656371, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29816; Mature: 29816

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRAMSITIKSAQDIAGMRLACRLASEVLDSIAAHIQPGITTRDIDRIGAECMARQGTV
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCE
SATVGYQPPGYPPYPASLCTSVNHVVCHGIPNDKPLKKGDIVNVDVTVITPEGWYGDSSR
EEEECCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
MYLIGEASIAARRLCALTYDAMWHGIVQVRPGAHLGDVGHAIQQFAESQGCSVVREFCGH
EEEEECHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCC
GIGRKFHEEPQVLHYGRPGTLAELRPGMVFTIEPMINAGRREVKEFGNDGWTIVTKDHSL
CCCCHHCCCCCEEECCCCCCHHHCCCCEEEEECHHHCCCHHHHHHHCCCCCEEEEECCCC
SAQWEHTVLVTPTGYEVLTLSAGSPPLPNFVAATAT
CCCCCEEEEECCCCCEEEEEECCCCCCCCCEEECCC
>Mature Secondary Structure
MDNRAMSITIKSAQDIAGMRLACRLASEVLDSIAAHIQPGITTRDIDRIGAECMARQGTV
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCE
SATVGYQPPGYPPYPASLCTSVNHVVCHGIPNDKPLKKGDIVNVDVTVITPEGWYGDSSR
EEEECCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
MYLIGEASIAARRLCALTYDAMWHGIVQVRPGAHLGDVGHAIQQFAESQGCSVVREFCGH
EEEEECHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCC
GIGRKFHEEPQVLHYGRPGTLAELRPGMVFTIEPMINAGRREVKEFGNDGWTIVTKDHSL
CCCCHHCCCCCEEECCCCCCHHHCCCCEEEEECHHHCCCHHHHHHHCCCCCEEEEECCCC
SAQWEHTVLVTPTGYEVLTLSAGSPPLPNFVAATAT
CCCCCEEEEECCCCCEEEEEECCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]