Click here to switch to the map view.

The map label for this gene is dgdR [H]

Identifier: 121609853

GI number: 121609853

Start: 3250554

End: 3251555

Strand: Direct

Name: dgdR [H]

Synonym: Veis_2906

Alternate gene names: 121609853

Gene position: 3250554-3251555 (Clockwise)

Preceding gene: 121609852

Following gene: 121609854

Centisome position: 58.39

GC content: 60.58

Gene sequence:

>1002_bases
ATGAATCCAAACAGCCAGCCGCGCCAGCCGGATTGGGACTTGCTCGTCAGTTGGATTGCTGTCGTGGAGTCCGGCAGCAT
CTCCGAGGCGACGCGACTGTTGGATATCTCGCAGGCCGCCGTCTCCCAGAGGATCAAGCAACTGGAGACTTTCTTCGGGA
CGGCGCTGCTTGACCGCAGCACCCGTCCGGCGCAGCCTACTGCCGCCGGGCAGCGCCTTTTCCAACACGCGAAGGAACTG
CTCACGCAAGCCGACCAGATGGTCGAGAGCGTTCGCAGTGTCAGCCGCGCAAAGCGCATGGCCGTTCGGATCGGTTGTGT
CGATTCGTTCGCCGCCACCGTCGGCCCACTGCTCATCAAGGGCCTGTCCGGCTCGTCCCATCAGATCCGGCTGTGGTCGG
GCATTACGCCGACCCTCGACGCGCTCATCGAAAGCCGGCAGTTGGACTTGGCCGTGACGACGAGCGCTTTTCTGTCCGCC
GGCATTTCACGCGCCTGCCTTTTCTCTGAAAAATACTATGTCGTGCTGCCAACGGGATTCGACCTTCAGCCGCTGTGCTC
GTTGACAGAGCTTGGGCGGCAACTCAAATTCATTCGATACAGCGCGCGATCGGTCATCGGGCAGCAGGTGGATGACTACC
TTCGCCACTGTGGCGATCATCTGGAGCGGACCTACGAATTCGACACCACGGACCCCCTTCTCAGCCTGGTTGCCAACGGC
ATGGGATTTGCGCTGACCACGCCTTTGTGTATTTGGCAGTCCCGCCACTTCGTTCCGGAGATACATGTCGTCCCCCTGTC
GGCATTCCTTCGGCATGGCCGCGCCTATGCCGATTTGAGTCGGGCCTTTTTTCTTGCTTACCGCCAAGGCGAACTCGGCA
CCTTGCCCACCGAGGTCCGGGATTTGGTGAGAATCGCGGCGCGGCATCAGATCTCGAAAGACATCGCTGCCTGCCTTCAC
CTCGAAGCCGATGTTCTCTTGGTGTCGGAGAGCGATGACTGA

Upstream 100 bases:

>100_bases
TTCAGATACAACGCCCGTCATGCCGCCGGATGCCGATGGATGGCCTCGCCCGGACGCGGCAGACATTGGCCATTGCCTTC
ATTTCTTCGGTGTCGAACCC

Downstream 100 bases:

>100_bases
TTCATCGTTGCCGCGTGCGATACGCCGGCAGCTTTTGCAAAGGCACTGAATCGGTGTAATCCACCATTGCAATTTCCTCG
GGGCTATTTCCGGTCTATCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNPNSQPRQPDWDLLVSWIAVVESGSISEATRLLDISQAAVSQRIKQLETFFGTALLDRSTRPAQPTAAGQRLFQHAKEL
LTQADQMVESVRSVSRAKRMAVRIGCVDSFAATVGPLLIKGLSGSSHQIRLWSGITPTLDALIESRQLDLAVTTSAFLSA
GISRACLFSEKYYVVLPTGFDLQPLCSLTELGRQLKFIRYSARSVIGQQVDDYLRHCGDHLERTYEFDTTDPLLSLVANG
MGFALTTPLCIWQSRHFVPEIHVVPLSAFLRHGRAYADLSRAFFLAYRQGELGTLPTEVRDLVRIAARHQISKDIAACLH
LEADVLLVSESDD

Sequences:

>Translated_333_residues
MNPNSQPRQPDWDLLVSWIAVVESGSISEATRLLDISQAAVSQRIKQLETFFGTALLDRSTRPAQPTAAGQRLFQHAKEL
LTQADQMVESVRSVSRAKRMAVRIGCVDSFAATVGPLLIKGLSGSSHQIRLWSGITPTLDALIESRQLDLAVTTSAFLSA
GISRACLFSEKYYVVLPTGFDLQPLCSLTELGRQLKFIRYSARSVIGQQVDDYLRHCGDHLERTYEFDTTDPLLSLVANG
MGFALTTPLCIWQSRHFVPEIHVVPLSAFLRHGRAYADLSRAFFLAYRQGELGTLPTEVRDLVRIAARHQISKDIAACLH
LEADVLLVSESDD
>Mature_333_residues
MNPNSQPRQPDWDLLVSWIAVVESGSISEATRLLDISQAAVSQRIKQLETFFGTALLDRSTRPAQPTAAGQRLFQHAKEL
LTQADQMVESVRSVSRAKRMAVRIGCVDSFAATVGPLLIKGLSGSSHQIRLWSGITPTLDALIESRQLDLAVTTSAFLSA
GISRACLFSEKYYVVLPTGFDLQPLCSLTELGRQLKFIRYSARSVIGQQVDDYLRHCGDHLERTYEFDTTDPLLSLVANG
MGFALTTPLCIWQSRHFVPEIHVVPLSAFLRHGRAYADLSRAFFLAYRQGELGTLPTEVRDLVRIAARHQISKDIAACLH
LEADVLLVSESDD

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=108, Percent_Identity=38.8888888888889, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=236, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788297, Length=232, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI157672245, Length=224, Percent_Identity=25.8928571428571, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789204, Length=233, Percent_Identity=25.3218884120172, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36883; Mature: 36883

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNSQPRQPDWDLLVSWIAVVESGSISEATRLLDISQAAVSQRIKQLETFFGTALLDRS
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TRPAQPTAAGQRLFQHAKELLTQADQMVESVRSVSRAKRMAVRIGCVDSFAATVGPLLIK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GLSGSSHQIRLWSGITPTLDALIESRQLDLAVTTSAFLSAGISRACLFSEKYYVVLPTGF
CCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEHHHHHHHHCHHHHHEECCCEEEEEECCC
DLQPLCSLTELGRQLKFIRYSARSVIGQQVDDYLRHCGDHLERTYEFDTTDPLLSLVANG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
MGFALTTPLCIWQSRHFVPEIHVVPLSAFLRHGRAYADLSRAFFLAYRQGELGTLPTEVR
CCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
DLVRIAARHQISKDIAACLHLEADVLLVSESDD
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MNPNSQPRQPDWDLLVSWIAVVESGSISEATRLLDISQAAVSQRIKQLETFFGTALLDRS
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TRPAQPTAAGQRLFQHAKELLTQADQMVESVRSVSRAKRMAVRIGCVDSFAATVGPLLIK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GLSGSSHQIRLWSGITPTLDALIESRQLDLAVTTSAFLSAGISRACLFSEKYYVVLPTGF
CCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEHHHHHHHHCHHHHHEECCCEEEEEECCC
DLQPLCSLTELGRQLKFIRYSARSVIGQQVDDYLRHCGDHLERTYEFDTTDPLLSLVANG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
MGFALTTPLCIWQSRHFVPEIHVVPLSAFLRHGRAYADLSRAFFLAYRQGELGTLPTEVR
CCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
DLVRIAARHQISKDIAACLHLEADVLLVSESDD
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]