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The map label for this gene is pcaR [H]

Identifier: 121609454

GI number: 121609454

Start: 2829239

End: 2831146

Strand: Direct

Name: pcaR [H]

Synonym: Veis_2498

Alternate gene names: 121609454

Gene position: 2829239-2831146 (Clockwise)

Preceding gene: 121609445

Following gene: 121609455

Centisome position: 50.82

GC content: 69.23

Gene sequence:

>1908_bases
GTGGCAGGAACGGTGGCAACTGCCTCGGGCCGGTGCAGTATATCCAAATGTGTCTTGTGGTATGAAATCATTACCAAAAA
TTGGGCGCGCGCCCGTGCAGCATCTCCGGTCAGGGGGTGTGCACGGTTTGGGATGCGGCAAGCAACGGCGGGGATGAACG
GCGGGGATGAACGGCGGGGATGGTTTGCTCATCGCGGTCGCGGTGTCGTGCAGCCGCAGGCCAGGATTTTTCTGCTCCAC
CGATGCGGCGGGGTTTGCCATGGCAACGACATGGACCACACTTTGGGCCTGTCGCTGCCCATGTCTGCCGCCTGCCCGCC
CCGCGATCCGCGTTTTGCCACTACCTTGGCCCATGGCCTGGCCCTGCTCGAGGCTTTCGATGCCACCCATGCGGGCCTGA
CCAACAAGGAACTGGCCGAGCGTTCCGGCCTCTCGAAGGCCACTGTCTCGCGGCTGAGCCTGACCTTGCAGGCGCATGGC
CTGCTCGAGTGCGGGCCGGGCGAGCGCCGCCATCGTCTGGCCTCGGCTGCCCTGACCCTGGGCTATCCGCTGCTGGCCGG
ACTGGGTATCCGGCGCGAAGCGCGTTGGGGCATGAAGCAATTGGCGGATGAGTTGGGTGGCTCGGTTTCGCTGGGCCTGC
GTGAGCGCGCCCGCATGATTTATGTGGAGACCAGCCGCAGCAGCAATCCGATGGCCTTTTGCCCCGATGTCGGCGCCGCG
CTGCCGATGCTGCAAACCGCGATGGGTCGCGCCTGGCTGGCGGCGGCGCCCGAGGCCCTGCGGCGCGAGGTGCTGGCCTT
GCTGCGCCGGCACTTGCCGGCCGCCTGGGCCCAATGGTGCGGCAGCGTCGGGCCGGCCATCGAACATCTGCAGCGCCACG
GTTTTTGCGTCTCACATGCCGACTGGCAGTCGGATGTGTATGCGGTGGCCGTGCCGCTGAACGCGCCGGCCGATGCCGAG
CCTCTGGTCATCAACTGCGGCGTGCCGATCCGCAGCCTGCGCCCCGGCGAGCTCCAGAGCCGGGTGGCGCCGCGGCTGAT
GGCCCTGGCGCGCCGCATCGAGGCCCATTGGCGCGCCGCAACGCAGCCGGCAATGCCGGTGGCGCTGCCACTGGAGGTGG
CGCATGGCGCGGTGTCTGGCACGGTGTCCCATGCGCACACCCTGTCGCGCGGACTCGATTTGCTCCAATGCTTCCGCCCG
GGCGAAGTGCAACTGGGCCATGCCGAGTTGACGCGCCGCCTGCGCCTGCCCGGCCCCATCGTGGTGCGGCTGACCCACAC
GCTCGGCGCGCTGGGCTACCTGCGCCGTGGCGCCGCAGGCAGCGGCTATCGGCTCGGCGCTGCAACGGTGGCGCTGGGTT
ATCCGCTGCTGGCCCATCTGCGTGCGCGGCAGTTGGCCAGGCCCGGGATGATGGCCTTGTCCGAACGGGTCGGCGGGGCG
GTGTCGCTGGGCTTTCGGCACCGCAGCAGCATGGTCTATGTCGAGTCGGCCTGGCGTGGCGATGCCCGGCTGGTGCCGCC
GGACATCGGCACGCCGCTGCCCATGCTCAGCAGTGCCATGGGCCGCGCCTGGCTGGCCCATGCCAGCGCGGCGCAGCGGT
GCGCGGTGCTGAACCAACTGCGGGTGCAGGACCCGGCCAGCCACGCCCGTTATGCGCCGGACATCGAGCAGGCACGGCAA
GACCTGGCCCGCAAAGCCTATTGCTCGACGCGCGGGGATGTCCGCAAGGATGTCTACGCCTTCGCCGTGCCCTTCTCGCG
CCCGGTCGACGGCTTGCAACTGGTGATGAACTGTGGCGTGCTGGCTGCCCGGTTCAGCTTTGCCCAGGCCGAGCGCCAGG
TGGCCCAGCCCCTGTGCGAACTGGTCAGACAGGTAGAGGCGGCCCTGGGCCTGCGCGCTGCGCAGTGA

Upstream 100 bases:

>100_bases
GGGCGGGCCTGTCGGCTTGGCGCACAGCATGATTCACAAACCGACCCATTCATGGTGTCTTGTTGGCTGGCCTTGGGCAA
TGTCTGCCGGGGGGATCGAT

Downstream 100 bases:

>100_bases
AGCCGCGCCGGTATCGGCGCGTTCAACATACTGAAACAACGGTGGCCGGCAAGGGCCAGCGCAGCACACACTGGCCGCAG
CCCGATCACCTGCCGCCGCC

Product: regulatory protein IclR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MAGTVATASGRCSISKCVLWYEIITKNWARARAASPVRGCARFGMRQATAGMNGGDERRGWFAHRGRGVVQPQARIFLLH
RCGGVCHGNDMDHTLGLSLPMSAACPPRDPRFATTLAHGLALLEAFDATHAGLTNKELAERSGLSKATVSRLSLTLQAHG
LLECGPGERRHRLASAALTLGYPLLAGLGIRREARWGMKQLADELGGSVSLGLRERARMIYVETSRSSNPMAFCPDVGAA
LPMLQTAMGRAWLAAAPEALRREVLALLRRHLPAAWAQWCGSVGPAIEHLQRHGFCVSHADWQSDVYAVAVPLNAPADAE
PLVINCGVPIRSLRPGELQSRVAPRLMALARRIEAHWRAATQPAMPVALPLEVAHGAVSGTVSHAHTLSRGLDLLQCFRP
GEVQLGHAELTRRLRLPGPIVVRLTHTLGALGYLRRGAAGSGYRLGAATVALGYPLLAHLRARQLARPGMMALSERVGGA
VSLGFRHRSSMVYVESAWRGDARLVPPDIGTPLPMLSSAMGRAWLAHASAAQRCAVLNQLRVQDPASHARYAPDIEQARQ
DLARKAYCSTRGDVRKDVYAFAVPFSRPVDGLQLVMNCGVLAARFSFAQAERQVAQPLCELVRQVEAALGLRAAQ

Sequences:

>Translated_635_residues
MAGTVATASGRCSISKCVLWYEIITKNWARARAASPVRGCARFGMRQATAGMNGGDERRGWFAHRGRGVVQPQARIFLLH
RCGGVCHGNDMDHTLGLSLPMSAACPPRDPRFATTLAHGLALLEAFDATHAGLTNKELAERSGLSKATVSRLSLTLQAHG
LLECGPGERRHRLASAALTLGYPLLAGLGIRREARWGMKQLADELGGSVSLGLRERARMIYVETSRSSNPMAFCPDVGAA
LPMLQTAMGRAWLAAAPEALRREVLALLRRHLPAAWAQWCGSVGPAIEHLQRHGFCVSHADWQSDVYAVAVPLNAPADAE
PLVINCGVPIRSLRPGELQSRVAPRLMALARRIEAHWRAATQPAMPVALPLEVAHGAVSGTVSHAHTLSRGLDLLQCFRP
GEVQLGHAELTRRLRLPGPIVVRLTHTLGALGYLRRGAAGSGYRLGAATVALGYPLLAHLRARQLARPGMMALSERVGGA
VSLGFRHRSSMVYVESAWRGDARLVPPDIGTPLPMLSSAMGRAWLAHASAAQRCAVLNQLRVQDPASHARYAPDIEQARQ
DLARKAYCSTRGDVRKDVYAFAVPFSRPVDGLQLVMNCGVLAARFSFAQAERQVAQPLCELVRQVEAALGLRAAQ
>Mature_634_residues
AGTVATASGRCSISKCVLWYEIITKNWARARAASPVRGCARFGMRQATAGMNGGDERRGWFAHRGRGVVQPQARIFLLHR
CGGVCHGNDMDHTLGLSLPMSAACPPRDPRFATTLAHGLALLEAFDATHAGLTNKELAERSGLSKATVSRLSLTLQAHGL
LECGPGERRHRLASAALTLGYPLLAGLGIRREARWGMKQLADELGGSVSLGLRERARMIYVETSRSSNPMAFCPDVGAAL
PMLQTAMGRAWLAAAPEALRREVLALLRRHLPAAWAQWCGSVGPAIEHLQRHGFCVSHADWQSDVYAVAVPLNAPADAEP
LVINCGVPIRSLRPGELQSRVAPRLMALARRIEAHWRAATQPAMPVALPLEVAHGAVSGTVSHAHTLSRGLDLLQCFRPG
EVQLGHAELTRRLRLPGPIVVRLTHTLGALGYLRRGAAGSGYRLGAATVALGYPLLAHLRARQLARPGMMALSERVGGAV
SLGFRHRSSMVYVESAWRGDARLVPPDIGTPLPMLSSAMGRAWLAHASAAQRCAVLNQLRVQDPASHARYAPDIEQARQD
LARKAYCSTRGDVRKDVYAFAVPFSRPVDGLQLVMNCGVLAARFSFAQAERQVAQPLCELVRQVEAALGLRAAQ

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 68412; Mature: 68281

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTVATASGRCSISKCVLWYEIITKNWARARAASPVRGCARFGMRQATAGMNGGDERRG
CCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHCCCCCCCCCCC
WFAHRGRGVVQPQARIFLLHRCGGVCHGNDMDHTLGLSLPMSAACPPRDPRFATTLAHGL
HHHHCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALLEAFDATHAGLTNKELAERSGLSKATVSRLSLTLQAHGLLECGPGERRHRLASAALTL
HHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHEEEEECCCEECCCCHHHHHHHHHHHHH
GYPLLAGLGIRREARWGMKQLADELGGSVSLGLRERARMIYVETSRSSNPMAFCPDVGAA
HHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECHHCCCEEEEEEECCCCCCEEECCCHHHH
LPMLQTAMGRAWLAAAPEALRREVLALLRRHLPAAWAQWCGSVGPAIEHLQRHGFCVSHA
HHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCEEECC
DWQSDVYAVAVPLNAPADAEPLVINCGVPIRSLRPGELQSRVAPRLMALARRIEAHWRAA
CCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
TQPAMPVALPLEVAHGAVSGTVSHAHTLSRGLDLLQCFRPGEVQLGHAELTRRLRLPGPI
CCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCCCE
VVRLTHTLGALGYLRRGAAGSGYRLGAATVALGYPLLAHLRARQLARPGMMALSERVGGA
EEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCE
VSLGFRHRSSMVYVESAWRGDARLVPPDIGTPLPMLSSAMGRAWLAHASAAQRCAVLNQL
EEECEECCCCEEEEEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVQDPASHARYAPDIEQARQDLARKAYCSTRGDVRKDVYAFAVPFSRPVDGLQLVMNCGV
HCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHH
LAARFSFAQAERQVAQPLCELVRQVEAALGLRAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AGTVATASGRCSISKCVLWYEIITKNWARARAASPVRGCARFGMRQATAGMNGGDERRG
CCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHCCCCCCCCCCC
WFAHRGRGVVQPQARIFLLHRCGGVCHGNDMDHTLGLSLPMSAACPPRDPRFATTLAHGL
HHHHCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALLEAFDATHAGLTNKELAERSGLSKATVSRLSLTLQAHGLLECGPGERRHRLASAALTL
HHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHEEEEECCCEECCCCHHHHHHHHHHHHH
GYPLLAGLGIRREARWGMKQLADELGGSVSLGLRERARMIYVETSRSSNPMAFCPDVGAA
HHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECHHCCCEEEEEEECCCCCCEEECCCHHHH
LPMLQTAMGRAWLAAAPEALRREVLALLRRHLPAAWAQWCGSVGPAIEHLQRHGFCVSHA
HHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCEEECC
DWQSDVYAVAVPLNAPADAEPLVINCGVPIRSLRPGELQSRVAPRLMALARRIEAHWRAA
CCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
TQPAMPVALPLEVAHGAVSGTVSHAHTLSRGLDLLQCFRPGEVQLGHAELTRRLRLPGPI
CCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCCCE
VVRLTHTLGALGYLRRGAAGSGYRLGAATVALGYPLLAHLRARQLARPGMMALSERVGGA
EEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCE
VSLGFRHRSSMVYVESAWRGDARLVPPDIGTPLPMLSSAMGRAWLAHASAAQRCAVLNQL
EEECEECCCCEEEEEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVQDPASHARYAPDIEQARQDLARKAYCSTRGDVRKDVYAFAVPFSRPVDGLQLVMNCGV
HCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHH
LAARFSFAQAERQVAQPLCELVRQVEAALGLRAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]