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The map label for this gene is ywbI [H]

Identifier: 121609346

GI number: 121609346

Start: 2702730

End: 2703623

Strand: Direct

Name: ywbI [H]

Synonym: Veis_2389

Alternate gene names: 121609346

Gene position: 2702730-2703623 (Clockwise)

Preceding gene: 121609345

Following gene: 121609347

Centisome position: 48.55

GC content: 64.77

Gene sequence:

>894_bases
GTGAATCTGCATTTCGACCTGTTTGATTTGAAACTCTTCACCTACGTGGCTGAGGCGAGCAGCCTTACGCGCGGTGCGGA
CAGGGCCTGCATTTCACTGGCCGCCGCGTCCACGCGCATCAAGCAGATGGAGGAAGCCATCGGCGGCAAGTTGCTCAATC
GCACGGCGCAGGGGGTGAATCTGACGGCCGCCGGCTCGGCTGTGCTCTACCACGCCAAGCGGGTGATGCAGCAGATGGAG
CATCTGCGCTGCGACATGCAGGATTTCGGCAAGGGCATCAAGGGCCATGTGCGCGTGTTCGCCAACACCAGTTCCATCAC
CGAGTACCTGCCGGAAAAGCTGGCTGGTTTTTTGACCCGCCATCCGGCGGTGCAGGTCGACCTGCGCGAATACCTCAGCG
AGGAGATCGTGCGTCTGGTGGCCGACGGCAGTGCCGACATCGGCATTTTGGCCGGCGATGTGCATACCGGCCAATTCGAC
GCCTGGTCTTTTGGGCGCAACCAACTGGTGCTGGCGCTTCCGGCCGGGCACCCGCTGGCCGACGCGGGTGCGGCGGCTTT
CGTTGACACCCTGGGCGAGCAGCATGTGGGCTTGCACCATGGCAGCGCCATCCACCGCTTCCTGATGCGCAAGGCCGAAT
TGGCGGGCCAGGGCTACAGCCCGCGCATACAGGTCAGCAGCTTCGAGGCGATTTGTCTGATGATCGAGGCCGGTGTCGGT
GTCGGCGTGCTGCCGGCCTCTTCCGCGCGCCGCCTGGCCAAAGCGCTGCGCATCACCATCGTGCCCCTGACCGACCACTG
GGCCGAGCGCGAGCTCAAGATCGTCACCCGTAGCCGCGAGTTGCTGCCGGCTTCGGCGCGCGAGTTGCTCGACCACCTGG
CGCAGCCGGGTTAG

Upstream 100 bases:

>100_bases
AGTTTCTTTGCGTTGGACCGCTCGGCGGATGTCTTCAGTTGGGATCCGGTCTGAGGTTTGCGGGACAAATTGCAGGACAA
TCGGGCCTTGTGAGGCCCTT

Downstream 100 bases:

>100_bases
TGCGCCGGGTTTTTCCAAAATCGGTTTCCTCCGGGCAAACCAGAAACTTCCAGAGACCGCAACAGAGACATGGGTATGAG
CACCACCACCGATTCGTTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNLHFDLFDLKLFTYVAEASSLTRGADRACISLAAASTRIKQMEEAIGGKLLNRTAQGVNLTAAGSAVLYHAKRVMQQME
HLRCDMQDFGKGIKGHVRVFANTSSITEYLPEKLAGFLTRHPAVQVDLREYLSEEIVRLVADGSADIGILAGDVHTGQFD
AWSFGRNQLVLALPAGHPLADAGAAAFVDTLGEQHVGLHHGSAIHRFLMRKAELAGQGYSPRIQVSSFEAICLMIEAGVG
VGVLPASSARRLAKALRITIVPLTDHWAERELKIVTRSRELLPASARELLDHLAQPG

Sequences:

>Translated_297_residues
MNLHFDLFDLKLFTYVAEASSLTRGADRACISLAAASTRIKQMEEAIGGKLLNRTAQGVNLTAAGSAVLYHAKRVMQQME
HLRCDMQDFGKGIKGHVRVFANTSSITEYLPEKLAGFLTRHPAVQVDLREYLSEEIVRLVADGSADIGILAGDVHTGQFD
AWSFGRNQLVLALPAGHPLADAGAAAFVDTLGEQHVGLHHGSAIHRFLMRKAELAGQGYSPRIQVSSFEAICLMIEAGVG
VGVLPASSARRLAKALRITIVPLTDHWAERELKIVTRSRELLPASARELLDHLAQPG
>Mature_297_residues
MNLHFDLFDLKLFTYVAEASSLTRGADRACISLAAASTRIKQMEEAIGGKLLNRTAQGVNLTAAGSAVLYHAKRVMQQME
HLRCDMQDFGKGIKGHVRVFANTSSITEYLPEKLAGFLTRHPAVQVDLREYLSEEIVRLVADGSADIGILAGDVHTGQFD
AWSFGRNQLVLALPAGHPLADAGAAAFVDTLGEQHVGLHHGSAIHRFLMRKAELAGQGYSPRIQVSSFEAICLMIEAGVG
VGVLPASSARRLAKALRITIVPLTDHWAERELKIVTRSRELLPASARELLDHLAQPG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=285, Percent_Identity=25.9649122807018, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI157672245, Length=240, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786713, Length=258, Percent_Identity=29.4573643410853, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788887, Length=242, Percent_Identity=25.6198347107438, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788748, Length=291, Percent_Identity=25.085910652921, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790399, Length=274, Percent_Identity=22.992700729927, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787806, Length=275, Percent_Identity=22.5454545454545, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI2367136, Length=249, Percent_Identity=24.4979919678715, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790208, Length=285, Percent_Identity=25.2631578947368, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786401, Length=191, Percent_Identity=26.1780104712042, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32204; Mature: 32204

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHFDLFDLKLFTYVAEASSLTRGADRACISLAAASTRIKQMEEAIGGKLLNRTAQGVN
CCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTAAGSAVLYHAKRVMQQMEHLRCDMQDFGKGIKGHVRVFANTSSITEYLPEKLAGFLTR
EEECCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHC
HPAVQVDLREYLSEEIVRLVADGSADIGILAGDVHTGQFDAWSFGRNQLVLALPAGHPLA
CCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEECCCCEEEEEECCCCCCH
DAGAAAFVDTLGEQHVGLHHGSAIHRFLMRKAELAGQGYSPRIQVSSFEAICLMIEAGVG
HHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHEEEEEEECCCC
VGVLPASSARRLAKALRITIVPLTDHWAERELKIVTRSRELLPASARELLDHLAQPG
CEECCCHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLHFDLFDLKLFTYVAEASSLTRGADRACISLAAASTRIKQMEEAIGGKLLNRTAQGVN
CCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTAAGSAVLYHAKRVMQQMEHLRCDMQDFGKGIKGHVRVFANTSSITEYLPEKLAGFLTR
EEECCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHC
HPAVQVDLREYLSEEIVRLVADGSADIGILAGDVHTGQFDAWSFGRNQLVLALPAGHPLA
CCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEECCCCEEEEEECCCCCCH
DAGAAAFVDTLGEQHVGLHHGSAIHRFLMRKAELAGQGYSPRIQVSSFEAICLMIEAGVG
HHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHEEEEEEECCCC
VGVLPASSARRLAKALRITIVPLTDHWAERELKIVTRSRELLPASARELLDHLAQPG
CEECCCHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]