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The map label for this gene is PPE51

Identifier: 121639019

GI number: 121639019

Start: 3454841

End: 3455983

Strand: Direct

Name: PPE51

Synonym: BCG_3159

Alternate gene names: 121639019

Gene position: 3454841-3455983 (Clockwise)

Preceding gene: 121639018

Following gene: 121639020

Centisome position: 78.98

GC content: 66.93

Gene sequence:

>1143_bases
ATGGATTTCGCACTGTTACCACCGGAAGTCAACTCCGCCCGGATGTACACCGGCCCTGGGGCAGGATCGCTGTTGGCTGC
CGCGGGCGGCTGGGATTCGCTGGCCGCCGAGTTGGCCACCACAGCCGAGGCATATGGATCGGTGCTGTCCGGACTGGCCG
CCTTGCATTGGCGTGGACCGGCAGCGGAATCGATGGCGGTGACGGCCGCTCCCTATATCGGTTGGCTGTACACGACCGCC
GAAAAGACACAGCAAACAGCGATCCAAGCCAGGGCGGCAGCGCTGGCCTTCGAGCAAGCATACGCAATGACCCTGCCGCC
ACCGGTGGTAGCGGCCAACCGGATACAGCTGCTAGCACTGATCGCGACGAACTTCTTCGGCCAGAACACTGCGGCGATCG
CGGCCACCGAGGCACAGTACGCCGAGATGTGGGCCCAGGACGCCGCCGCGATGTACGGTTACGCCACCGCCTCAGCGGCT
GCGGCCCTGCTGACACCGTTCTCCCCGCCGCGGCAGACCACCAACCCGGCCGGCCTGACCGCTCAGGCCGCCGCGGTCAG
CCAGGCCACCGACCCACTGTCGCTGCTGATTGAGACGGTGACCCAAGCGCTGCAAGCGCTGACGATTCCGAGCTTCATCC
CTGAGGACTTCACCTTCCTTGACGCCATATTCGCTGGATATGCCACGGTAGGTGTGACGCAGGATGTCGAGTCCTTTGTT
GCCGGGACCATCGGGGCCGAGAGCAACCTAGGCCTTTTGAACGTCGGCGACGAGAATCCCGCGGAGGTGACACCGGGCGA
CTTTGGGATCGGCGAGTTGGTTTCCGCGACCAGTCCCGGCGGTGGGGTGTCTGCGTCGGGTGCCGGCGGTGCGGCGAGCG
TCGGCAACACGGTGCTCGCGAGTGTCGGCCGGGCAAACTCGATTGGGCAACTATCGGTCCCACCGAGCTGGGCCGCGCCC
TCGACGCGCCCTGTCTCGGCATTGTCGCCCGCCGGCCTGACCACACTCCCGGGGACCGACGTGGCCGAGCACGGGATGCC
AGGTGTACCGGGGGTGCCAGTGGCAGCAGGGCGAGCCTCCGGCGTCCTACCTCGATACGGGGTTCGGCTCACGGTGATGG
CCCACCCACCCGCGGCAGGGTAA

Upstream 100 bases:

>100_bases
ACGGCCAGTGCCAGCAACACCGCTGGCACTCCACCTTGACCCATTCAGTTCTCGACCAGCACGACACCGTATCCGCACAA
ATGTAAGGATCTGAGACACA

Downstream 100 bases:

>100_bases
CCCGGCGCCTAACCGACAGGCGGCCCGTTGGGCGTAAACGTCCAATTGTCAGGATTCTTCGGCGAGTACACCACCGGAAG
TATTTGACCGACGGTCGGCC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPAAESMAVTAAPYIGWLYTTA
EKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAA
AALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV
AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAP
STRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG

Sequences:

>Translated_380_residues
MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPAAESMAVTAAPYIGWLYTTA
EKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAA
AALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV
AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAP
STRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG
>Mature_380_residues
MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPAAESMAVTAAPYIGWLYTTA
EKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAA
AALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV
AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAP
STRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE51_MYCTU (Q7D623)

Other databases:

- EMBL:   BX842582
- EMBL:   AE000516
- PIR:   A70646
- RefSeq:   NP_337747.1
- RefSeq:   YP_177935.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q7D623
- SMR:   Q7D623
- EnsemblBacteria:   EBMYCT00000001267
- EnsemblBacteria:   EBMYCT00000070432
- GeneID:   888835
- GeneID:   923408
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3221
- KEGG:   mtu:Rv3136
- TIGR:   MT3221
- TubercuList:   Rv3136
- GeneTree:   EBGT00050000014887
- HOGENOM:   HBG572308
- OMA:   PRFASAN
- ProtClustDB:   CLSK799958
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 37980; Mature: 37980

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP
CCCCCCCCCCCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL
CCCCEEEECCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHH
IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT
HHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA
HHCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS
HCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCC
GVLPRYGVRLTVMAHPPAAG
CCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP
CCCCCCCCCCCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL
CCCCEEEECCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHH
IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT
HHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA
HHCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS
HCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCC
GVLPRYGVRLTVMAHPPAAG
CCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036