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The map label for this gene is PPE50 [H]

Identifier: 121639018

GI number: 121639018

Start: 3453044

End: 3454189

Strand: Direct

Name: PPE50 [H]

Synonym: BCG_3158

Alternate gene names: 121639018

Gene position: 3453044-3454189 (Clockwise)

Preceding gene: 121639014

Following gene: 121639019

Centisome position: 78.94

GC content: 66.32

Gene sequence:

>1146_bases
ATGGACTACGCGTTCTTACCACCGGAGATCAACTCCGCGCGTATGTACAGCGGTCCCGGACCGAATTCAATGTTGGTTGC
CGCGGCCAGCTGGGATGCGCTGGCCGCGGAGTTAGCATCCGCAGCAGAGAACTACGGCTCGGTGATTGCGCGTCTGACCG
GTATGCACTGGTGGGGCCCGGCGTCCACGTCGATGCTGGCCATGTCGGCTCCATACGTGGAATGGCTGGAGCGGACCGCC
GCGCAGACCAAGCAGACCGCTACCCAAGCCAGAGCGGCGGCGGCGGCATTCGAGCAGGCTCATGCGATGACGGTGCCCCC
AGCGTTGGTCACCGCCAACCGAGCCGAGCTGAAAGCACTGATCGCGTCGAACCTCCTGGGCCAGAACACCGCAGCGATCG
CAGCCATCGAGGCACAGTACGCCGAGATGTGGGCACAAGACGCGGCCGCGATGTACGGCTACGCCACCACCTCAGCGGCG
GCGAGACAGTTGACGCCGTTCTCCTCGCCACAACAGACCACCAACCCGGCCGGGCTAGCCGCCCAGAACGCCGCGGTCAC
CCAGGCCGCCACCAACTCCGCCGGGAACACGCCGACCGCATTGTCGCAACTGTCCTCTTTCCTGTCGCAGGCAGTAAAGG
CGCCGACGGGATGGCCCAACATTCTCCCGGATGACTTCACCATCCTTGACGGCATATTGGCTGCGTACGCAACGGTCGGC
GTGACGCAGGACATCGAGTCGATATGTGCGGGCATCATCGGGGCCGAGAACAACTTGGGCCTTTTAGGCGCCGCCAGTGA
GAATCCGGCGGAGTTGGCGCCGGGCGCGTTCGGGATCGATGCGGCACTCAGTTCGGCAGAAAAAGGCGCTGCTGCGAGCA
TGCACGATGCGGTACTCGCGAGTGCCGGCCGGGCGGGTTCGATCGGGCCGATGTCCGTACCACCGTCCTGGGCCACGCCC
TCGAGCACCCCGGTCTCGGCGTTGTCGGGCGCCGGCTTAACCACGCTCGACGGGACCGACGTAGCCGAGCACGGTACGCC
CGGCTTGCCAGGGGTGCCAGCAGGGACAGACAAGCGAGCCTCGGGTGTCATCCCCCGATACGGGGTCCGGCTCACGGTGA
TGTCGCGCCCGCCGGCGGCTGGGTGA

Upstream 100 bases:

>100_bases
CGCTCGTGACCATGGGGGGAGCCACTGCCGTCTCCCGCATGCCCACACCGAGGTCCGAATTGGGCTGGGTGCGCAATCGA
CGTTAGGGGCCTGCGGAGTA

Downstream 100 bases:

>100_bases
CGCGGCTGCCGCTGTCACTGTCATCCTGTAGGCGAGCCAACCCCGGTCACCACTAGCGTGCCGCAAAGATCTGCGCGCGG
CCCGCGCACTGAGCCCCAGG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGPASTSMLAMSAPYVEWLERTA
AQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKALIASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAA
ARQLTPFSSPQQTTNPAGLAAQNAAVTQAATNSAGNTPTALSQLSSFLSQAVKAPTGWPNILPDDFTILDGILAAYATVG
VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGIDAALSSAEKGAAASMHDAVLASAGRAGSIGPMSVPPSWATP
SSTPVSALSGAGLTTLDGTDVAEHGTPGLPGVPAGTDKRASGVIPRYGVRLTVMSRPPAAG

Sequences:

>Translated_381_residues
MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGPASTSMLAMSAPYVEWLERTA
AQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKALIASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAA
ARQLTPFSSPQQTTNPAGLAAQNAAVTQAATNSAGNTPTALSQLSSFLSQAVKAPTGWPNILPDDFTILDGILAAYATVG
VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGIDAALSSAEKGAAASMHDAVLASAGRAGSIGPMSVPPSWATP
SSTPVSALSGAGLTTLDGTDVAEHGTPGLPGVPAGTDKRASGVIPRYGVRLTVMSRPPAAG
>Mature_381_residues
MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGPASTSMLAMSAPYVEWLERTA
AQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKALIASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAA
ARQLTPFSSPQQTTNPAGLAAQNAAVTQAATNSAGNTPTALSQLSSFLSQAVKAPTGWPNILPDDFTILDGILAAYATVG
VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGIDAALSSAEKGAAASMHDAVLASAGRAGSIGPMSVPPSWATP
SSTPVSALSGAGLTTLDGTDVAEHGTPGLPGVPAGTDKRASGVIPRYGVRLTVMSRPPAAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022171
- InterPro:   IPR000030 [H]

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 38408; Mature: 38408

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP
CCCCCCCCCCCCCEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHH
IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCC
AQNAAVTQAATNSAGNTPTALSQLSSFLSQAVKAPTGWPNILPDDFTILDGILAAYATVG
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGIDAALSSAEKGAAASMHDAVLA
CHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHH
SAGRAGSIGPMSVPPSWATPSSTPVSALSGAGLTTLDGTDVAEHGTPGLPGVPAGTDKRA
HCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEECCCCCHHHCCCCCCCCCCCCCCCCC
SGVIPRYGVRLTVMSRPPAAG
CCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP
CCCCCCCCCCCCCEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHH
IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCC
AQNAAVTQAATNSAGNTPTALSQLSSFLSQAVKAPTGWPNILPDDFTILDGILAAYATVG
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGIDAALSSAEKGAAASMHDAVLA
CHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHH
SAGRAGSIGPMSVPPSWATPSSTPVSALSGAGLTTLDGTDVAEHGTPGLPGVPAGTDKRA
HCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEECCCCCHHHCCCCCCCCCCCCCCCCC
SGVIPRYGVRLTVMSRPPAAG
CCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]