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The map label for this gene is 121639014

Identifier: 121639014

GI number: 121639014

Start: 3448261

End: 3449259

Strand: Direct

Name: 121639014

Synonym: BCG_3154

Alternate gene names: NA

Gene position: 3448261-3449259 (Clockwise)

Preceding gene: 121639012

Following gene: 121639018

Centisome position: 78.83

GC content: 66.77

Gene sequence:

>999_bases
ATGAACACCCATTTCCCGGACGCCGAAACCGTGCGAACGGTTCTCACCCTGGCCGTCCGGGCCCCCTCCATCCACAACAC
GCAGCCGTGGCGGTGGCGGGTATGCCCGACGAGTCTGGAGCTGTTCTCTAGACCCGATATGCAGCTGCGTAGCACCGATC
CGGACGGGCGTGAGTTGATCCTCAGCTGTGGTGTGGCATTGCACCACTGCGTCGTCGCTTTGGCGTCGCTGGGCTGGCAG
GCCAAGGTAAACCGTTTCCCCGATCCCAAGGACCGCTGCCATCTGGCCACCATCGGGGTACAACCGCTTGTTCCCGATCA
GGCCGATGTCGCCTTGGCGGCGGCCATACCGCGGCGACGCACCGATCGGCGCGCCTACAGTTGCTGGCCGGTGCCAGGAG
GTGACATCGCGTTGATGGCCGCAAGAGCAGCCCGTGGCGGGGTCATGCTGCGGCAGGTCAGTGCCCTAGACCGAATGAAA
GCCATTGTGGCGCAGGCTGTCTTGGACCACGTGACCGACGAGGAATATCTGCGCGAGCTCACCATTTGGAGTGGGCGCTA
CGGTTCAGTGGCCGGGGTTCCCGCCCGCAACGAGCCGCCATCAGACCCCAGTGCCCCGATCCCCGGTCGCCTGTTCGCCG
GGCCCGGTCTGTCTCAGCCGTCCGACGTCTTACCCGCTGACGACGGCGCCGCGATCCTGGCACTAGGCACCGAGACAGAC
GACCGGTTGGCCCGGCTGCGCGCCGGCGAGGCCGCCAGCATCGTCTTGTTGACCGCGACGGCAATGGGGCTGGCGTGCTG
CCCGATCACCGAACCGCTGGAGATCGCCAAGACCCGCGACGCGGTCCGTGCCGAGGTGTTCGGCGCCGGCGGCTACCCCC
AGATGCTGCTGCGAGTGGGTTGGGCACCGATCAATGCCGACCCGTTGCCACCGACGCCACGGCGCGAACTGTCCCAGGTC
GTTGAGTGGCCGGAAGAGCTACTGCGACAACGGTGCTGA

Upstream 100 bases:

>100_bases
AGGTCCTCCGCTGGCGAGCCTTCGTGCTCTGCCACCGCGGCTGTCGACGCGCGATCCTTAATAGATGACCGCAGCCGTTG
ATGGGAAAGGCCCGGCAGCC

Downstream 100 bases:

>100_bases
CCATCGCAGCACTGTTCCGCTCGCGCCCGGTACGCTCGCGAGGGTGAATTCGCCGCCGGCCTGCTCTGCCCGCTGCCGCA
GGTTCGTTAAGCCGCTTCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNTHFPDAETVRTVLTLAVRAPSIHNTQPWRWRVCPTSLELFSRPDMQLRSTDPDGRELILSCGVALHHCVVALASLGWQ
AKVNRFPDPKDRCHLATIGVQPLVPDQADVALAAAIPRRRTDRRAYSCWPVPGGDIALMAARAARGGVMLRQVSALDRMK
AIVAQAVLDHVTDEEYLRELTIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDVLPADDGAAILALGTETD
DRLARLRAGEAASIVLLTATAMGLACCPITEPLEIAKTRDAVRAEVFGAGGYPQMLLRVGWAPINADPLPPTPRRELSQV
VEWPEELLRQRC

Sequences:

>Translated_332_residues
MNTHFPDAETVRTVLTLAVRAPSIHNTQPWRWRVCPTSLELFSRPDMQLRSTDPDGRELILSCGVALHHCVVALASLGWQ
AKVNRFPDPKDRCHLATIGVQPLVPDQADVALAAAIPRRRTDRRAYSCWPVPGGDIALMAARAARGGVMLRQVSALDRMK
AIVAQAVLDHVTDEEYLRELTIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDVLPADDGAAILALGTETD
DRLARLRAGEAASIVLLTATAMGLACCPITEPLEIAKTRDAVRAEVFGAGGYPQMLLRVGWAPINADPLPPTPRRELSQV
VEWPEELLRQRC
>Mature_332_residues
MNTHFPDAETVRTVLTLAVRAPSIHNTQPWRWRVCPTSLELFSRPDMQLRSTDPDGRELILSCGVALHHCVVALASLGWQ
AKVNRFPDPKDRCHLATIGVQPLVPDQADVALAAAIPRRRTDRRAYSCWPVPGGDIALMAARAARGGVMLRQVSALDRMK
AIVAQAVLDHVTDEEYLRELTIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDVLPADDGAAILALGTETD
DRLARLRAGEAASIVLLTATAMGLACCPITEPLEIAKTRDAVRAEVFGAGGYPQMLLRVGWAPINADPLPPTPRRELSQV
VEWPEELLRQRC

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitroreductase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3131_MYCTU (P95195)

Other databases:

- EMBL:   BX842582
- EMBL:   AE000516
- PIR:   D70645
- RefSeq:   NP_217647.1
- RefSeq:   NP_337741.1
- ProteinModelPortal:   P95195
- EnsemblBacteria:   EBMYCT00000000614
- EnsemblBacteria:   EBMYCT00000069141
- GeneID:   888838
- GeneID:   923427
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3217
- KEGG:   mtu:Rv3131
- TIGR:   MT3217
- TubercuList:   Rv3131
- GeneTree:   EBGT00050000015619
- HOGENOM:   HBG696381
- OMA:   ASCPITE
- ProtClustDB:   CLSK792300
- GO:   GO:0005829
- GO:   GO:0040007
- InterPro:   IPR000415

Pfam domain/function: PF00881 Nitroreductase; SSF55469 Nitroreductase

EC number: NA

Molecular weight: Translated: 35979; Mature: 35979

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: BINDING 314-314

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHFPDAETVRTVLTLAVRAPSIHNTQPWRWRVCPTSLELFSRPDMQLRSTDPDGRELI
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHCCCCCEEECCCCCHHHHH
LSCGVALHHCVVALASLGWQAKVNRFPDPKDRCHLATIGVQPLVPDQADVALAAAIPRRR
HHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCC
TDRRAYSCWPVPGGDIALMAARAARGGVMLRQVSALDRMKAIVAQAVLDHVTDEEYLREL
CCCCCEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDVLPADDGAAILALGTETD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCH
DRLARLRAGEAASIVLLTATAMGLACCPITEPLEIAKTRDAVRAEVFGAGGYPQMLLRVG
HHHHHHHCCCCCEEEEEEHHHHHHEECCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHC
WAPINADPLPPTPRRELSQVVEWPEELLRQRC
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTHFPDAETVRTVLTLAVRAPSIHNTQPWRWRVCPTSLELFSRPDMQLRSTDPDGRELI
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHCCCCCEEECCCCCHHHHH
LSCGVALHHCVVALASLGWQAKVNRFPDPKDRCHLATIGVQPLVPDQADVALAAAIPRRR
HHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCC
TDRRAYSCWPVPGGDIALMAARAARGGVMLRQVSALDRMKAIVAQAVLDHVTDEEYLREL
CCCCCEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDVLPADDGAAILALGTETD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCH
DRLARLRAGEAASIVLLTATAMGLACCPITEPLEIAKTRDAVRAEVFGAGGYPQMLLRVG
HHHHHHHCCCCCEEEEEEHHHHHHEECCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHC
WAPINADPLPPTPRRELSQVVEWPEELLRQRC
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036