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The map label for this gene is clpX [H]

Identifier: 121638340

GI number: 121638340

Start: 2723378

End: 2724658

Strand: Reverse

Name: clpX [H]

Synonym: BCG_2477c

Alternate gene names: 121638340

Gene position: 2724658-2723378 (Counterclockwise)

Preceding gene: 121638343

Following gene: 121638339

Centisome position: 62.28

GC content: 61.59

Gene sequence:

>1281_bases
ATGGCGCGCATAGGAGACGGTGGTGACCTGCTGAAGTGCTCGTTCTGCGGGAAGAGCCAAAAACAGGTCAAGAAGCTCAT
TGCCGGCCCCGGCGTGTACATCTGCGATGAGTGCATCGACCTGTGTAACGAGATCATCGAAGAGGAACTCGCCGACGCCG
ACGATGTGAAACTCGACGAGCTGCCCAAGCCGGCCGAGATCCGGGAGTTCCTCGAGGGCTACGTCATCGGGCAAGATACC
GCCAAACGCACGCTGGCCGTGGCGGTGTACAACCACTACAAGCGGATCCAGGCCGGGGAGAAGGGCCGTGACTCCCGATG
TGAGCCCGTTGAGTTGACCAAGTCGAACATCTTGATGCTCGGACCCACCGGTTGTGGCAAGACCTACCTGGCCCAGACGC
TGGCCAAGATGCTTAACGTGCCGTTTGCCATCGCCGACGCCACCGCGCTGACCGAGGCCGGTTACGTCGGCGAGGACGTC
GAGAACATCTTGCTCAAACTTATTCAGGCCGCCGACTACGACGTCAAACGCGCCGAGACCGGCATCATCTACATCGACGA
GGTCGACAAGATCGCCCGCAAGAGTGAGAACCCGTCGATTACTCGCGACGTCTCCGGTGAGGGCGTTCAGCAGGCCTTGC
TGAAAATCCTGGAGGGCACTCAGGCGTCGGTTCCGCCGCAGGGGGCCCGTAAGCACCCGCATCAAGAGTTCATCCAGATC
GACACCACCAACGTGCTGTTCATCGTCGCGGGAGCGTTCGCCGGGCTGGAGAAGATCATTTACGAGCGCGTCGGCAAGCG
GGGCCTCGGCTTTGGCGCCGAGGTTCGTTCCAAGGCCGAGATCGACACCACCGACCACTTTGCCGACGTGATGCCGGAGG
ATCTGATCAAGTTCGGCCTGATCCCGGAATTCATCGGCCGCCTGCCGGTGGTCGCCTCGGTCACCAACCTGGACAAAGAG
TCGTTGGTCAAGATCCTGTCCGAGCCGAAGAACGCTTTGGTCAAGCAGTACATCCGGCTGTTCGAGATGGATGGCGTGGA
GTTGGAGTTCACCGACGATGCGCTGGAAGCGATCGCCGACCAGGCGATCCATCGCGGCACCGGTGCCCGCGGCCTGCGGG
CGATCATGGAAGAAGTCCTGCTGCCGGTGATGTACGACATCCCGAGCCGCGACGATGTCGCCAAAGTGGTGGTCACCAAG
GAGACCGTGCAGGACAACGTGTTGCCGACAATCGTGCCACGCAAGCCGTCCCGTTCGGAGCGCCGCGACAAGAGCGCGTA
G

Upstream 100 bases:

>100_bases
GGTGCTAACGGTCGCGGGGGGCCGGAGCAAGCGGGTAGCGTCGGGGCATACACGGGGCACGGCAACACGAACGGCGATCA
GGAAGTAGGCCATCAGCATT

Downstream 100 bases:

>100_bases
CCCCGCGACGACTGCATGTCGGGCACCGTTGTGGCAGTGCCGCCACGGGTGGCGCGTGCGCTGGACCTGCTGAATTTCTC
GTTGGCTGATGTTCGCGACG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPAEIREFLEGYVIGQDT
AKRTLAVAVYNHYKRIQAGEKGRDSRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDV
ENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGARKHPHQEFIQI
DTTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGLIPEFIGRLPVVASVTNLDKE
SLVKILSEPKNALVKQYIRLFEMDGVELEFTDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
ETVQDNVLPTIVPRKPSRSERRDKSA

Sequences:

>Translated_426_residues
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPAEIREFLEGYVIGQDT
AKRTLAVAVYNHYKRIQAGEKGRDSRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDV
ENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGARKHPHQEFIQI
DTTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGLIPEFIGRLPVVASVTNLDKE
SLVKILSEPKNALVKQYIRLFEMDGVELEFTDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
ETVQDNVLPTIVPRKPSRSERRDKSA
>Mature_425_residues
ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPAEIREFLEGYVIGQDTA
KRTLAVAVYNHYKRIQAGEKGRDSRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVE
NILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGARKHPHQEFIQID
TTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGLIPEFIGRLPVVASVTNLDKES
LVKILSEPKNALVKQYIRLFEMDGVELEFTDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKE
TVQDNVLPTIVPRKPSRSERRDKSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=346, Percent_Identity=49.4219653179191, Blast_Score=304, Evalue=8e-83,
Organism=Escherichia coli, GI1786642, Length=412, Percent_Identity=62.1359223300971, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1790366, Length=108, Percent_Identity=47.2222222222222, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71982908, Length=308, Percent_Identity=45.1298701298701, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=308, Percent_Identity=45.1298701298701, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=411, Percent_Identity=37.4695863746959, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=38.9558232931727, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6319704, Length=428, Percent_Identity=39.2523364485981, Blast_Score=278, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24648289, Length=330, Percent_Identity=46.6666666666667, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24648291, Length=330, Percent_Identity=46.6666666666667, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46797; Mature: 46666

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDE
CCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHC
LPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGEKGRDSRCEPVELTKSNILML
CCCCHHHHHHHHCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEE
GPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAET
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCC
GIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGARKHPHQEFIQI
CEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHEEE
DTTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL
CCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHCHHHHHHHCC
IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYIRLFEMDGVELEFTDDALEAIAD
HHHHHCCCCHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
QAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRSE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHCCCCCCCCCCCCCCHH
RRDKSA
HCCCCC
>Mature Secondary Structure 
ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDE
CCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHC
LPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGEKGRDSRCEPVELTKSNILML
CCCCHHHHHHHHCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEE
GPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAET
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCC
GIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGARKHPHQEFIQI
CEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHEEE
DTTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL
CCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHCHHHHHHHCC
IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYIRLFEMDGVELEFTDDALEAIAD
HHHHHCCCCHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
QAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRSE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHCCCCCCCCCCCCCCHH
RRDKSA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA