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The map label for this gene is cysW [H]

Identifier: 121638278

GI number: 121638278

Start: 2660055

End: 2660873

Strand: Reverse

Name: cysW [H]

Synonym: BCG_2413c

Alternate gene names: 121638278

Gene position: 2660873-2660055 (Counterclockwise)

Preceding gene: 121638279

Following gene: 121638277

Centisome position: 60.83

GC content: 62.52

Gene sequence:

>819_bases
ATGACCTCCTTGCCGGCGGCTCGCTACCTCGTCCGATCGGTCGCGCTGGGGTACGTCTTTGTGCTGTTGATCGTTCCGGT
AGCGCTGATCCTGTGGCGGACCTTCGAACCGGGCTTTGGCCAGTTCTACGCCTGGATCAGTACCCCGGCGGCGATATCAG
CGCTGAACCTGTCGCTACTGGTGGTGGCTATCGTGGTACCGCTGAACGTGATCTTTGGAGTCACGACGGCATTGGTGCTG
GCCCGCAACCGGTTCCGCGGCAAGGGCGTCTTGCAGGCGATTATCGATCTGCCTTTTGCGGTTTCACCCGTCATCGTGGG
CGTCTCGTTGATCTTGCTGTGGGGATCGGCCGGCGCCCTGGGCTTCGTCGAGCAGGACCTTGGCTTCAAGATCATCTTCG
GGCTGCCGGGAATCGTGCTTGCCAGCATGTTCGTCACCTGTCCATTCGTGGTGCGCGAAGTGGAACCCGTATTGCACGAA
TTGGGCACCGACCAGGAGCAGGCGGCGGCGACGCTGGGTTCCGGTTGGTGGCAGACATTCTGGCGAATCACGCTGCCCTC
CATCCGGTGGGGCCTGACGTACGGCATCGTATTGACCGTCGCTCGAACCCTCGGCGAATATGGGGCGGTCATCATCGTCT
CGTCGAACCTTCCAGGGACATCGCAAACACTGACCCTCTTGGTCTCCGACCGCTACCACCGTGGGGCCGAGTACGGTGCC
TACGCGCTGTCGACGCTGCTGATGGCGGTTTCCGTGGTGGTGCTGATCGTCCAGATGGTGCTAGACGCCCGCCGGGCACG
AGCGGTCAGCGAGGGCTGA

Upstream 100 bases:

>100_bases
CGGCCGCGATATCGGTTGTATTGCTCTCGATTTCGTTCATTGTGCTGCTCATCCTACGTGTCGTCGGCGCGCGTGCGGCC
AAACGTGAGGAGATGGCCGC

Downstream 100 bases:

>100_bases
GAAGGAGACGGTGAAAATGACCTACGCCATCGTCGTGGCCGACGCCACCAAACGCTACGGCGACTTCGTCGCACTTGACC
ACGTGGATTTCGTCGTACCG

Product: putative sulfate-transport integral membrane protein ABC transporter cysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFGQFYAWISTPAAISALNLSLLVVAIVVPLNVIFGVTTALVL
ARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGALGFVEQDLGFKIIFGLPGIVLASMFVTCPFVVREVEPVLHE
LGTDQEQAAATLGSGWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNLPGTSQTLTLLVSDRYHRGAEYGA
YALSTLLMAVSVVVLIVQMVLDARRARAVSEG

Sequences:

>Translated_272_residues
MTSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFGQFYAWISTPAAISALNLSLLVVAIVVPLNVIFGVTTALVL
ARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGALGFVEQDLGFKIIFGLPGIVLASMFVTCPFVVREVEPVLHE
LGTDQEQAAATLGSGWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNLPGTSQTLTLLVSDRYHRGAEYGA
YALSTLLMAVSVVVLIVQMVLDARRARAVSEG
>Mature_271_residues
TSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFGQFYAWISTPAAISALNLSLLVVAIVVPLNVIFGVTTALVLA
RNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGALGFVEQDLGFKIIFGLPGIVLASMFVTCPFVVREVEPVLHEL
GTDQEQAAATLGSGWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNLPGTSQTLTLLVSDRYHRGAEYGAY
ALSTLLMAVSVVVLIVQMVLDARRARAVSEG

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=279, Percent_Identity=36.9175627240143, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1788764, Length=230, Percent_Identity=33.9130434782609, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786980, Length=208, Percent_Identity=35.5769230769231, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29303; Mature: 29172

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFGQFYAWISTPAAISALNLSLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHH
VVAIVVPLNVIFGVTTALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GFVEQDLGFKIIFGLPGIVLASMFVTCPFVVREVEPVLHELGTDQEQAAATLGSGWWQTF
CHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
WRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNLPGTSQTLTLLVSDRYHRGAEYGA
HHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHEEEEECHHHCCCHHHH
YALSTLLMAVSVVVLIVQMVLDARRARAVSEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFGQFYAWISTPAAISALNLSLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHH
VVAIVVPLNVIFGVTTALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GFVEQDLGFKIIFGLPGIVLASMFVTCPFVVREVEPVLHELGTDQEQAAATLGSGWWQTF
CHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
WRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNLPGTSQTLTLLVSDRYHRGAEYGA
HHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHEEEEECHHHCCCHHHH
YALSTLLMAVSVVVLIVQMVLDARRARAVSEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]