Click here to switch to the map view.

The map label for this gene is cysT [H]

Identifier: 121638279

GI number: 121638279

Start: 2660870

End: 2661721

Strand: Reverse

Name: cysT [H]

Synonym: BCG_2414c

Alternate gene names: 121638279

Gene position: 2661721-2660870 (Counterclockwise)

Preceding gene: 121638280

Following gene: 121638278

Centisome position: 60.85

GC content: 64.32

Gene sequence:

>852_bases
ATGACGGAATCGTTGGTCGGCGAACGCCGCGCGCCGCAGTTCCGCGCGCGCCTTTCCGGCCCCGCGGGCCCCCCTTCCGT
TCGGGTCGGTATGGCAGTGGTGTGGCTTTCGGTGATCGTGCTGTTGCCGCTGGCCGCCATCGTCTGGCAGGCCGCGGGCG
GTGGTTGGCGGGCCTTCTGGCTGGCGGTCTCGTCGCATGCCGCGATGGAGTCGTTCCGGGTAACGCTGACGATTTCGACC
GCAGTCACGGTCATCAACCTGGTGTTCGGCTTGCTGATCGCCTGGGTGCTGGTGCGTGACGACTTCGCTGGCAAGCGGAT
CGTCGATGCGATTATCGATCTGCCGTTTGCGTTGCCCACCATCGTCGCCAGCCTGGTGATGTTGGCACTGTACGGGAACA
ACAGCCCGGTGGGGCTTCATTTTCAACACACCGCGACCGGTGTTGGGGTGGCGTTGGCGTTCGTCACATTGCCGTTCGTG
GTGCGCGCCGTGCAGCCGGTGCTGCTGGAAATCGATCGCGAGACCGAGGAGGCGGCGGCGTCGCTGGGCGCTAATGGTGC
CAAAATCTTCACTTCGGTGGTGTTGCCGTCGCTGACGCCGGCATTGTTATCCGGTGCGGGCCTGGCGTTTTCGCGCGCTA
TCGGCGAGTTCGGTTCGGTGGTTCTGATCGGCGGGGCCGTGCCGGGCAAGACCGAGGTGTCCTCGCAATGGATTCGCACC
CTGATCGAGAACGACGACCGCACCGGAGCGGCCGCGATATCGGTTGTATTGCTCTCGATTTCGTTCATTGTGCTGCTCAT
CCTACGTGTCGTCGGCGCGCGTGCGGCCAAACGTGAGGAGATGGCCGCATGA

Upstream 100 bases:

>100_bases
TGTGGACGATCGCCGACCTCGGTGGCTGGGGCAGCGTGGATCCTCAGCTGTTCGACAAGGCGACCGGCAGCATCACCAAG
ATTTATCTGCGGGCCACCGG

Downstream 100 bases:

>100_bases
CCTCCTTGCCGGCGGCTCGCTACCTCGTCCGATCGGTCGCGCTGGGGTACGTCTTTGTGCTGTTGATCGTTCCGGTAGCG
CTGATCCTGTGGCGGACCTT

Product: putative sulfate-transport integral membrane protein ABC transporter cysT

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTESLVGERRAPQFRARLSGPAGPPSVRVGMAVVWLSVIVLLPLAAIVWQAAGGGWRAFWLAVSSHAAMESFRVTLTIST
AVTVINLVFGLLIAWVLVRDDFAGKRIVDAIIDLPFALPTIVASLVMLALYGNNSPVGLHFQHTATGVGVALAFVTLPFV
VRAVQPVLLEIDRETEEAAASLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVVLIGGAVPGKTEVSSQWIRT
LIENDDRTGAAAISVVLLSISFIVLLILRVVGARAAKREEMAA

Sequences:

>Translated_283_residues
MTESLVGERRAPQFRARLSGPAGPPSVRVGMAVVWLSVIVLLPLAAIVWQAAGGGWRAFWLAVSSHAAMESFRVTLTIST
AVTVINLVFGLLIAWVLVRDDFAGKRIVDAIIDLPFALPTIVASLVMLALYGNNSPVGLHFQHTATGVGVALAFVTLPFV
VRAVQPVLLEIDRETEEAAASLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVVLIGGAVPGKTEVSSQWIRT
LIENDDRTGAAAISVVLLSISFIVLLILRVVGARAAKREEMAA
>Mature_282_residues
TESLVGERRAPQFRARLSGPAGPPSVRVGMAVVWLSVIVLLPLAAIVWQAAGGGWRAFWLAVSSHAAMESFRVTLTISTA
VTVINLVFGLLIAWVLVRDDFAGKRIVDAIIDLPFALPTIVASLVMLALYGNNSPVGLHFQHTATGVGVALAFVTLPFVV
RAVQPVLLEIDRETEEAAASLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVVLIGGAVPGKTEVSSQWIRTL
IENDDRTGAAAISVVLLSISFIVLLILRVVGARAAKREEMAA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=238, Percent_Identity=40.7563025210084, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI87082099, Length=262, Percent_Identity=33.587786259542, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786980, Length=203, Percent_Identity=31.5270935960591, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787080, Length=201, Percent_Identity=23.3830845771144, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29683; Mature: 29552

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESLVGERRAPQFRARLSGPAGPPSVRVGMAVVWLSVIVLLPLAAIVWQAAGGGWRAFW
CCCCHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAVSSHAAMESFRVTLTISTAVTVINLVFGLLIAWVLVRDDFAGKRIVDAIIDLPFALPT
HHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHH
IVASLVMLALYGNNSPVGLHFQHTATGVGVALAFVTLPFVVRAVQPVLLEIDRETEEAAA
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVVLIGGAVPGKTEVSSQWIRT
HHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
LIENDDRTGAAAISVVLLSISFIVLLILRVVGARAAKREEMAA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TESLVGERRAPQFRARLSGPAGPPSVRVGMAVVWLSVIVLLPLAAIVWQAAGGGWRAFW
CCCHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAVSSHAAMESFRVTLTISTAVTVINLVFGLLIAWVLVRDDFAGKRIVDAIIDLPFALPT
HHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHH
IVASLVMLALYGNNSPVGLHFQHTATGVGVALAFVTLPFVVRAVQPVLLEIDRETEEAAA
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVVLIGGAVPGKTEVSSQWIRT
HHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
LIENDDRTGAAAISVVLLSISFIVLLILRVVGARAAKREEMAA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]