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The map label for this gene is hemN [H]

Identifier: 121638267

GI number: 121638267

Start: 2647037

End: 2648164

Strand: Reverse

Name: hemN [H]

Synonym: BCG_2402c

Alternate gene names: 121638267

Gene position: 2648164-2647037 (Counterclockwise)

Preceding gene: 121638268

Following gene: 121638265

Centisome position: 60.54

GC content: 68.97

Gene sequence:

>1128_bases
ATGCCCGGACAACCGTTCGGGGTCTACCTGCACGTCCCGTTCTGCCTGACCCGTTGCGGGTACTGCGACTTCAATACCTA
CACCCCGGCCCAGCTGGGTGGCGTCAGCCCGGACCGTTGGCTGCTGGCGCTGCGGGCGGAGCTCGAACTGGCGGCCGCCA
AGCTGGACGCACCGACGGTGCATACCGTGTATGTGGGTGGCGGGACGCCATCGCTGCTCGGGGGGGAGCGCCTGGCCACG
TTGCTGGACATGGTGCGGGACCACTTTGTGCTGGCGCCCGACGCCGAAGTCAGCACCGAGGCCAACCCCGAGTCGACGTG
GCCGGAGTTCTTCGCCACGATCCGCGCGGCCGGTTACACGCGGGTGTCGCTCGGCATGCAGTCGGTGGCCCCGAGGGTGC
TGGCAACCTTGGACCGGGTGCACTCGCCGGGCCGGGCGGCGGCCGCGGCCACCGAGGCGATAGCGGAGGGCTTCACACAC
GTCAACCTCGACCTGATCTATGGAACCCCGGGGGAGTCCGACGACGACCTGGTGCGCTCAGTGGACGCCACGGTGCAGGC
CGGTGTGGATCATGTGTCCGCGTATGCCTTGGTCGTCGAGCACGGCACGGCACTGGCTCGCCGGGTTCGGCGTGGTGAGC
TGGCCGCGCCCGATGACGACGTGCTGGCGCATCGCTACGAGTTGGTCGATGCTCGGCTGTCGGCGGCCGGGTTTGCCTGG
TACGAGGTGTCCAATTGGTGTCGACCGGGCGGCGAGTGCCGGCACAACCTGGGTTATTGGGACGGTGGCCAGTGGTGGGG
CGCAGGTCCGGGCGCGCACGGCTACATTGGCGTGACACGCTGGTGGAATGTCAAGCACCCCAACACTTACGCCGAGATAC
TGGCCGGGGCGACGTTGCCGGTAGCGGGCTTCGAGCAGCTGGGCGCCGACGCTTTGCACACCGAAGACGTGTTGCTGAAG
GTCCGGCTGCGCCAGGGGCTACCGCTCGCCCGGCTAGGGGCTGCCGAACGGGAACGTGCCGAGGCGGTGTTGGCCGACGG
ATTGCTGGACTACCACGGCGACCGACTGGTCCTCACCGGCCGGGGGCGATTGCTGGCCGACGCGGTGGTGCGCACTCTGC
TGGGCTAA

Upstream 100 bases:

>100_bases
GCCTGCGTTACATTGCTGGCCACCCTAGCTGGTACGCGCTATGCGATGATTTGGCATGGTATTTCGGCAGGCACCAGTTG
AGCTGCCCGGCCTGGCGCCC

Downstream 100 bases:

>100_bases
CCGATCGAAGCCCCGGTGGCAGGGAACCATTGCCCGACGATGCGGGCGATCTCGATGTACAGCGGGATCCCGATCGTGAC
GTTGTAGGAGAACGTCAAAC

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVYVGGGTPSLLGGERLAT
LLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTH
VNLDLIYGTPGESDDDLVRSVDATVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGADALHTEDVLLK
VRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG

Sequences:

>Translated_375_residues
MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVYVGGGTPSLLGGERLAT
LLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTH
VNLDLIYGTPGESDDDLVRSVDATVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGADALHTEDVLLK
VRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG
>Mature_374_residues
PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVYVGGGTPSLLGGERLATL
LDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHV
NLDLIYGTPGESDDDLVRSVDATVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY
EVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGADALHTEDVLLKV
RLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=273, Percent_Identity=38.0952380952381, Blast_Score=164, Evalue=9e-41,
Organism=Escherichia coli, GI1789325, Length=382, Percent_Identity=32.9842931937173, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87082341, Length=306, Percent_Identity=26.1437908496732, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 40364; Mature: 40233

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV
CCCCCEEEEEECHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCE
HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT
EEEEECCCCCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCE
RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS
EEHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHH
VDATVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
HHHHHHHCHHHHHHHHHEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEE
YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP
EEHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCCCCC
VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG
CCCHHHHCCCCCCHHHHHHEEHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEC
RGRLLADAVVRTLLG
CCCHHHHHHHHHHCC
>Mature Secondary Structure 
PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV
CCCCEEEEEECHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCE
HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT
EEEEECCCCCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCE
RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS
EEHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHH
VDATVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
HHHHHHHCHHHHHHHHHEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEE
YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP
EEHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCCCCC
VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG
CCCHHHHCCCCCCHHHHHHEEHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEC
RGRLLADAVVRTLLG
CCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]