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The map label for this gene is PPE22 [H]

Identifier: 121637612

GI number: 121637612

Start: 1936714

End: 1937871

Strand: Reverse

Name: PPE22 [H]

Synonym: BCG_1743c

Alternate gene names: 121637612

Gene position: 1937871-1936714 (Counterclockwise)

Preceding gene: 121637613

Following gene: 121637611

Centisome position: 44.3

GC content: 67.7

Gene sequence:

>1158_bases
ATGGCTTTTGGGGCGTTGCCACCGGAGGTGAACTCCGGGCGCATGTATTGCGGCCCGGGCTCGGCACCGATGGTTGCCGC
AGCGTCCGCGTGGAACGGGCTGGCCGCCGAGCTCAGTGTGGCCGCCGTCGGCTACGAGCGGGTGATCACGACGCTGCAAA
CCGAAGAATGGCTGGGTCCGGCGTCGACGTTGATGGTCGAAGCGGTCGCCCCGTATGTGGCGTGGATGCGAGCCACCGCC
ATCCAAGCTGAGCAGGCAGCCAGTCAGGCGCGTGCGGCGGCGGCCGCTTACGAAACCGCGTTTGCCGCCATTGTGCCCCC
GCCGCTGATCGCGGCCAATCGCGCGCGGCTCACGTCGCTGGTCACGCATAACGTGTTCGGTCAAAACACCGCATCAATCG
CGGCCACCGAAGCTCAATACGCTGAAATGTGGGCCCAAGACGCCATGGCCATGTACGGTTACGCGGGCTCCTCGGCGACC
GCGACCAAAGTGACGCCGTTTGCCCCGCCGCCGAACACCACCAGCCCATCCGCCGCGGCGACGCAGTTGTCCGCAGTCGC
CAAAGCCGCCGGCACCTCAGCCGGCGCGGCGCAGAGCGCAATAGCGGAGCTGATCGCCCACTTGCCCAACACGCTGCTGG
GCCTCACCTCGCCCCTGTCGTCCGCGTTGACCGCCGCCGCGACCCCGGGGTGGCTGGAATGGTTCATCAACTGGTATCTG
CCGATATCACAGCTGTTTTACAACACCGTGGGTTTGCCATATTTCGCCATTGGTATTGGCAACAGCCTTATTACATCGTG
GCGGGCGCTGGGATGGATCGGTCCCGAGGCCGCCGAAGCTGCCGCCGCGGCGCCGGCGGCCGTCGGCGCCGCGGTTGGCG
GTACCGGACCCGTATCCGCGGGTCTAGGCAACGCGGCCACCATCGGCAAGTTATCGGTGCCGCCCAACTGGGCAGGGGCC
AGTCCGAGCCTAGCCCCGACCGTGGGTTCGGCCTCCGCACCCCTGGTCAGCGATATCGTCGAGCAACCGGAGGCCGGTGC
GGCGGGAAACCTGTTGGGCGGCATGCCGCTAGCCGGTTCGGGCACCGGTACGGGGGGTGCGGGTCCCCGCTACGGGTTCC
GGGTTACGGTGATGTCCCGGCCGCCGTTTGCCGGATAA

Upstream 100 bases:

>100_bases
TATGGGACGCCGATATGGAAGACGACTCACCGTGATGGCTGACCGGCCGAACGTCGGATAGCCCACCGAAAACCCGTGAC
GAGGTAAGGAGTTCATAGCG

Downstream 100 bases:

>100_bases
CGCGAGGCCTTCCCTACCCCAGAACTTGAGGACGCCATATATGCCGGACGATATCGCGGCTGCCGACCCGACAGACACCC
AGCCGCACCTGCGTCGGGAC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGPASTLMVEAVAPYVAWMRATA
IQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSLVTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSAT
ATKVTPFAPPPNTTSPSAAATQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYL
PISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSVPPNWAGA
SPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG

Sequences:

>Translated_385_residues
MAFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGPASTLMVEAVAPYVAWMRATA
IQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSLVTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSAT
ATKVTPFAPPPNTTSPSAAATQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYL
PISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSVPPNWAGA
SPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG
>Mature_384_residues
AFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGPASTLMVEAVAPYVAWMRATAI
QAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSLVTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATA
TKVTPFAPPPNTTSPSAAATQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYLP
ISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSVPPNWAGAS
PSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022171
- InterPro:   IPR000030 [H]

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 38386; Mature: 38254

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP
CCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYL
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
PISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSA
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHCCCCCCCCC
GLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGS
CCCCCCEECEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
GTGTGGAGPRYGFRVTVMSRPPFAG
CCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
AFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP
CCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYL
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
PISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSA
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHCCCCCCCCC
GLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGS
CCCCCCEECEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
GTGTGGAGPRYGFRVTVMSRPPFAG
CCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]