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The map label for this gene is typA [H]

Identifier: 121637097

GI number: 121637097

Start: 1325512

End: 1327398

Strand: Direct

Name: typA [H]

Synonym: BCG_1227

Alternate gene names: 121637097

Gene position: 1325512-1327398 (Clockwise)

Preceding gene: 121637096

Following gene: 121637098

Centisome position: 30.3

GC content: 66.67

Gene sequence:

>1887_bases
GTGCCATTCCGCAACGTTGCCATCGTCGCGCACGTCGACCACGGCAAGACCACCCTGGTTGACGCCATGTTGCGGCAGTC
CGGGGCGCTGCGTGAACGCGGTGAGCTGCAGGAACGGGTGATGGACACGGGCGATCTGGAGCGGGAGAAGGGCATCACCA
TCCTGGCCAAGAACACCGCCGTGCACCGCCATCACCCGGATGGAACCGTCACCGTAATCAATGTCATAGACACCCCGGGG
CACGCGGACTTCGGTGGCGAGGTGGAGCGCGGGCTGTCCATGGTGGACGGGGTGCTGCTGCTGGTCGACGCCTCCGAGGG
TCCATTGCCGCAGACGCGGTTTGTTCTGCGTAAAGCGCTGGCCGCCCATTTGCCGGTGATTCTGGTGGTCAACAAGACAG
ACCGGCCCGACGCCCGCATCGCCGAGGTCGTGGACGCCAGCCACGACCTGTTGCTAGATGTCGCGTCCGACCTTGACGAC
GAAGCGGCCGCAGCGGCCGAACACGCGCTGGGCCTGCCGACGCTGTACGCATCCGGGCGCGCCGGGGTGGCGAGCACCAC
GGCGCCGCCCGACGGCCAGGTTCCCGACGGCACCAACCTGGATCCGTTGTTCGAGGTGCTCGAAAAGCATGTGCCGCCGC
CGAAAGGAGAGCCGGACGCACCGCTGCAGGCGCTGGTCACCAACCTGGACGCGTCGACCTTTCTGGGTCGGTTGGCGCTG
ATCCGCATCTACAACGGCCGCATCCGCAAAGGCCAGCAGGTTGCGTGGATCCGTCAGGTGGATGGTCAGCAGACCGTCAC
CACTGCCAAGATCACCGAATTGTTGGCCACCGAAGGCGTGGAACGCAAACCAACCGACGCTGCCGTCGCCGGCGATATCG
TCGCCGTCGCCGGCCTGCCCGAGATCATGATCGGCGACACGCTGGCCGCTTCCGCGAATCCCGTTGCCCTGCCCAGGATT
ACCGTGGACGAGCCGGCGATCTCGGTCACCATCGGCACCAACACCTCGCCGCTGGCGGGCAAGGTGGGTGGTCACAAGCT
CACCGCGCGCATGGTCCGAAGCAGGCTGGATGCCGAGCTGGTGGGCAACGTGTCGATTCGTGTCGTCGACATCGGCGCCC
CGGACGCCTGGGAGGTACAGGGTCGCGGCGAGCTGGCGCTGGCGGTGCTGGTCGAGCAGATGCGCCGAGAGGGTTTCGAA
TTGACCGTGGGTAAGCCACAGGTGGTGACCAAGACCATCGATGGCACGCTGCACGAGCCATTCGAGTCGATGACCGTCGA
CTGCCCCGAGGAGTACATCGGCGCGGTCACGCAATTGATGGCCGCGCGCAAGGGCCGCATGGTGGAGATGGCCAACCACA
CCACCGGCTGGGTCCGCATGGACTTCGTGGTTCCCAGTCGCGGCCTGATTGGGTGGCGCACCGACTTCCTCACCGAGACC
CGTGGCTCCGGTGTCGGGCATGCGGTGTTCGACGGATACCGGCCATGGGCGGGGGAGATCCGGGCCCGCCACACCGGTTC
TCTGGTATCGGACCGGGCCGGCGCCATCACACCGTTCGCGTTGCTGCAACTCGCCGATCGGGGGCAGTTCTTCGTCGAGC
CCGGCCAACAGACCTACGAGGGCATGGTCGTCGGGATCAACCCCCGTCCGGAGGACCTCGACATCAATGTCACCCGGGAG
AAGAAGCTGACCAACATGCGCTCATCGACCGCGGATGTCATCGAGACGCTGGCCAAGCCGCTGCAGCTGGATCTCGAGCG
CGCCATGGAGTTATGTGCGCCCGACGAATGCGTCGAGGTGACCCCGGAGATCGTGCGGATCCGCAAAGTCGAGCTGGCCG
CCGCCGCCCGGGCTCGCAGCCGGGCGCGCACCAAGGCGCGTGGCTAG

Upstream 100 bases:

>100_bases
CTACATCGTGTACCGCAGCCGCGAGGTGGCGGCCAAGCACGAATTGATCGGTTCCGCGCCGCGTCGTCGTGGGTGGTAGT
TCTCTGCCACAATCACCGTC

Downstream 100 bases:

>100_bases
CAACTTGGCGCGCTGGCCGCGCGAGCGTAACGCCACTGCGAAATCCAGCCCGGCTTTTCGCAGCCGGGTTACGCTCGTGG
GGGTACTGGATAGCCTGATG

Product: putative GTP-binding translation elongation factor typA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MPFRNVAIVAHVDHGKTTLVDAMLRQSGALRERGELQERVMDTGDLEREKGITILAKNTAVHRHHPDGTVTVINVIDTPG
HADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAAHLPVILVVNKTDRPDARIAEVVDASHDLLLDVASDLDD
EAAAAAEHALGLPTLYASGRAGVASTTAPPDGQVPDGTNLDPLFEVLEKHVPPPKGEPDAPLQALVTNLDASTFLGRLAL
IRIYNGRIRKGQQVAWIRQVDGQQTVTTAKITELLATEGVERKPTDAAVAGDIVAVAGLPEIMIGDTLAASANPVALPRI
TVDEPAISVTIGTNTSPLAGKVGGHKLTARMVRSRLDAELVGNVSIRVVDIGAPDAWEVQGRGELALAVLVEQMRREGFE
LTVGKPQVVTKTIDGTLHEPFESMTVDCPEEYIGAVTQLMAARKGRMVEMANHTTGWVRMDFVVPSRGLIGWRTDFLTET
RGSGVGHAVFDGYRPWAGEIRARHTGSLVSDRAGAITPFALLQLADRGQFFVEPGQQTYEGMVVGINPRPEDLDINVTRE
KKLTNMRSSTADVIETLAKPLQLDLERAMELCAPDECVEVTPEIVRIRKVELAAAARARSRARTKARG

Sequences:

>Translated_628_residues
MPFRNVAIVAHVDHGKTTLVDAMLRQSGALRERGELQERVMDTGDLEREKGITILAKNTAVHRHHPDGTVTVINVIDTPG
HADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAAHLPVILVVNKTDRPDARIAEVVDASHDLLLDVASDLDD
EAAAAAEHALGLPTLYASGRAGVASTTAPPDGQVPDGTNLDPLFEVLEKHVPPPKGEPDAPLQALVTNLDASTFLGRLAL
IRIYNGRIRKGQQVAWIRQVDGQQTVTTAKITELLATEGVERKPTDAAVAGDIVAVAGLPEIMIGDTLAASANPVALPRI
TVDEPAISVTIGTNTSPLAGKVGGHKLTARMVRSRLDAELVGNVSIRVVDIGAPDAWEVQGRGELALAVLVEQMRREGFE
LTVGKPQVVTKTIDGTLHEPFESMTVDCPEEYIGAVTQLMAARKGRMVEMANHTTGWVRMDFVVPSRGLIGWRTDFLTET
RGSGVGHAVFDGYRPWAGEIRARHTGSLVSDRAGAITPFALLQLADRGQFFVEPGQQTYEGMVVGINPRPEDLDINVTRE
KKLTNMRSSTADVIETLAKPLQLDLERAMELCAPDECVEVTPEIVRIRKVELAAAARARSRARTKARG
>Mature_627_residues
PFRNVAIVAHVDHGKTTLVDAMLRQSGALRERGELQERVMDTGDLEREKGITILAKNTAVHRHHPDGTVTVINVIDTPGH
ADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAAHLPVILVVNKTDRPDARIAEVVDASHDLLLDVASDLDDE
AAAAAEHALGLPTLYASGRAGVASTTAPPDGQVPDGTNLDPLFEVLEKHVPPPKGEPDAPLQALVTNLDASTFLGRLALI
RIYNGRIRKGQQVAWIRQVDGQQTVTTAKITELLATEGVERKPTDAAVAGDIVAVAGLPEIMIGDTLAASANPVALPRIT
VDEPAISVTIGTNTSPLAGKVGGHKLTARMVRSRLDAELVGNVSIRVVDIGAPDAWEVQGRGELALAVLVEQMRREGFEL
TVGKPQVVTKTIDGTLHEPFESMTVDCPEEYIGAVTQLMAARKGRMVEMANHTTGWVRMDFVVPSRGLIGWRTDFLTETR
GSGVGHAVFDGYRPWAGEIRARHTGSLVSDRAGAITPFALLQLADRGQFFVEPGQQTYEGMVVGINPRPEDLDINVTREK
KLTNMRSSTADVIETLAKPLQLDLERAMELCAPDECVEVTPEIVRIRKVELAAAARARSRARTKARG

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=532, Percent_Identity=27.2556390977444, Blast_Score=156, Evalue=7e-38,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=42.8571428571429, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=38.6206896551724, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI18390331, Length=137, Percent_Identity=40.1459854014599, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI217272892, Length=135, Percent_Identity=37.7777777777778, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI217272894, Length=135, Percent_Identity=37.7777777777778, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310132016, Length=112, Percent_Identity=39.2857142857143, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI310110807, Length=112, Percent_Identity=39.2857142857143, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI310123363, Length=112, Percent_Identity=39.2857142857143, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI25306283, Length=145, Percent_Identity=38.6206896551724, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI19923640, Length=146, Percent_Identity=38.3561643835616, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI25306287, Length=146, Percent_Identity=38.3561643835616, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI94966752, Length=88, Percent_Identity=44.3181818181818, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI34147630, Length=154, Percent_Identity=34.4155844155844, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI53729339, Length=248, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI53729337, Length=248, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI48994988, Length=621, Percent_Identity=45.8937198067633, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1788922, Length=523, Percent_Identity=27.7246653919694, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789738, Length=156, Percent_Identity=37.8205128205128, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1790835, Length=138, Percent_Identity=31.1594202898551, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1789737, Length=139, Percent_Identity=36.6906474820144, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790412, Length=139, Percent_Identity=36.6906474820144, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=534, Percent_Identity=26.0299625468165, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17556745, Length=146, Percent_Identity=39.7260273972603, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988811, Length=132, Percent_Identity=39.3939393939394, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988819, Length=133, Percent_Identity=39.0977443609023, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=153, Percent_Identity=39.2156862745098, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17552882, Length=133, Percent_Identity=34.5864661654135, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17556456, Length=309, Percent_Identity=27.831715210356, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323320, Length=538, Percent_Identity=25.8364312267658, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324707, Length=145, Percent_Identity=40, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6320593, Length=145, Percent_Identity=40, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6323098, Length=138, Percent_Identity=40.5797101449275, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322359, Length=144, Percent_Identity=36.1111111111111, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324166, Length=141, Percent_Identity=38.2978723404255, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324761, Length=305, Percent_Identity=25.2459016393443, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI78706572, Length=539, Percent_Identity=26.530612244898, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574573, Length=139, Percent_Identity=39.568345323741, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24585711, Length=149, Percent_Identity=38.9261744966443, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24585713, Length=149, Percent_Identity=38.9261744966443, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24585709, Length=149, Percent_Identity=38.9261744966443, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21357743, Length=133, Percent_Identity=37.593984962406, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24582462, Length=137, Percent_Identity=40.8759124087591, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI221458488, Length=151, Percent_Identity=42.3841059602649, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19921738, Length=254, Percent_Identity=28.740157480315, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281363316, Length=264, Percent_Identity=26.1363636363636, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17864358, Length=264, Percent_Identity=26.1363636363636, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28572034, Length=140, Percent_Identity=35.7142857142857, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 67581; Mature: 67450

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFRNVAIVAHVDHGKTTLVDAMLRQSGALRERGELQERVMDTGDLEREKGITILAKNTA
CCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCCEEEEECCE
VHRHHPDGTVTVINVIDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKAL
EEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
AAHLPVILVVNKTDRPDARIAEVVDASHDLLLDVASDLDDEAAAAAEHALGLPTLYASGR
HHCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCC
AGVASTTAPPDGQVPDGTNLDPLFEVLEKHVPPPKGEPDAPLQALVTNLDASTFLGRLAL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHH
IRIYNGRIRKGQQVAWIRQVDGQQTVTTAKITELLATEGVERKPTDAAVAGDIVAVAGLP
HHEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEECCCC
EIMIGDTLAASANPVALPRITVDEPAISVTIGTNTSPLAGKVGGHKLTARMVRSRLDAEL
CCEECCCCCCCCCCEEECEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHH
VGNVSIRVVDIGAPDAWEVQGRGELALAVLVEQMRREGFELTVGKPQVVTKTIDGTLHEP
CCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEECCCCHHCC
FESMTVDCPEEYIGAVTQLMAARKGRMVEMANHTTGWVRMDFVVPSRGLIGWRTDFLTET
HHHCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECCCCCCEECHHHHHHC
RGSGVGHAVFDGYRPWAGEIRARHTGSLVSDRAGAITPFALLQLADRGQFFVEPGQQTYE
CCCCCCHHHHCCCCCCCCCHHHCCCCCHHHCCCCCCCHHHHHHHHCCCCEEECCCCCCCC
GMVVGINPRPEDLDINVTREKKLTNMRSSTADVIETLAKPLQLDLERAMELCAPDECVEV
CEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
TPEIVRIRKVELAAAARARSRARTKARG
CHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFRNVAIVAHVDHGKTTLVDAMLRQSGALRERGELQERVMDTGDLEREKGITILAKNTA
CCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCCEEEEECCE
VHRHHPDGTVTVINVIDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKAL
EEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
AAHLPVILVVNKTDRPDARIAEVVDASHDLLLDVASDLDDEAAAAAEHALGLPTLYASGR
HHCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCC
AGVASTTAPPDGQVPDGTNLDPLFEVLEKHVPPPKGEPDAPLQALVTNLDASTFLGRLAL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHH
IRIYNGRIRKGQQVAWIRQVDGQQTVTTAKITELLATEGVERKPTDAAVAGDIVAVAGLP
HHEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEECCCC
EIMIGDTLAASANPVALPRITVDEPAISVTIGTNTSPLAGKVGGHKLTARMVRSRLDAEL
CCEECCCCCCCCCCEEECEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHH
VGNVSIRVVDIGAPDAWEVQGRGELALAVLVEQMRREGFELTVGKPQVVTKTIDGTLHEP
CCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEECCCCHHCC
FESMTVDCPEEYIGAVTQLMAARKGRMVEMANHTTGWVRMDFVVPSRGLIGWRTDFLTET
HHHCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECCCCCCEECHHHHHHC
RGSGVGHAVFDGYRPWAGEIRARHTGSLVSDRAGAITPFALLQLADRGQFFVEPGQQTYE
CCCCCCHHHHCCCCCCCCCHHHCCCCCHHHCCCCCCCHHHHHHHHCCCCEEECCCCCCCC
GMVVGINPRPEDLDINVTREKKLTNMRSSTADVIETLAKPLQLDLERAMELCAPDECVEV
CEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
TPEIVRIRKVELAAAARARSRARTKARG
CHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]