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The map label for this gene is lpqW

Identifier: 121637098

GI number: 121637098

Start: 1327496

End: 1329403

Strand: Direct

Name: lpqW

Synonym: BCG_1228

Alternate gene names: 121637098

Gene position: 1327496-1329403 (Clockwise)

Preceding gene: 121637097

Following gene: 121637102

Centisome position: 30.35

GC content: 67.14

Gene sequence:

>1908_bases
ATGGGCGTGCCCAGCCCAGTCCGCCGCGTCTGTGTGACGGTCGGCGCGTTGGTCGCGCTGGCGTGTATGGTGTTGGCCGG
GTGCACGGTCAGCCCGCCGCCGGCACCCCAGAGCACTGATACGCCGCGCAGCACACCGCCCCCGCCGCGCCGCCCTACCC
AGATCATCATGGGCATCGACTGGATCGGCCCCGGGTTCAACCCGCATTTGCTGTCCGACCTGTCGCCGGTGAACGCCGCA
ATCAGTGCGTTGGTGTTGCCCAGCGCGTTCCGGCCGATTCCGGATCCCAACACGCCGACCGGTTCGCGCTGGGAGATGGA
CCCGACCCTGTTGGTTTCCGCCGACGTGACCAACAACCACCCGTTCACGGTGACCTACAAGATCCGGCCCGAGGCGCAGT
GGACGGACAACGCCCCGATCGCCGCCGACGACTTCTGGTATCTGTGGCAGCAGATGGTCACACAGCCGGGCGTCGTCGAC
CCCGCCGGATACCACCTGATCACCAGTGTCCAGTCGCTCGAGGGCGGTAAGCAGGCCGTCGTTACGTTCGCACAGCCCTA
CCCCGCTTGGCGTGAGTTGTTCACCGACATCCTGCCGGCGCACATCGTCAAGGACATACCAGGGGGCTTCGCGTCCGGTT
TGGCTCGAGCGCTGCCGGTGACAGGTGGACAGTTTCGGGTGGAAAACATCGACCCACAGCGCGATGAGATCCTGATCGCC
CGCAATGACCGTTACTGGGGCCCACCTTCCAAACCCGGCATCATTCTCTTCCGCCGGGCCGGGGCGCCGGCCGCGCTGGC
CGATTCGGTACGTAACGGAGACACCCAGGTCGCCCAGGTGCATGGTGGCTCGGCGGCCTTCGCCCAGTTGTCGGCCATCC
CCGACGTGCGGACCGCCCGGATCGTGACACCGCGGGTCATGCAGTTCACGCTGCGGGCAAACGTTCCCAAGCTGGCCGAC
ACCCAGGTTCGCAAGGCGATTTTGGGGTTGCTGGACGTGGACCTACTTGCCGCCGTGGGCGCCGGCACCGACAACACCGT
CACCTTGGACCAGGCGCAGATTCGTTCGCCGAGTGACCCGGGTTATGTTCCGACCGCGCCTCCCGCAATGAGCAGCGCCG
CCGCGCTGGGTCTGCTGGAGGCATCGGGATTCCAGGTCGACACCAACACGTCGGTGTCGCCGGCGCCGTCGGTCCCCGAT
TCGACGACCACGTCGGTGAGCACCGGGCCGCCGGAAGTCATCCGCGGCCGGATCAGCAAGGACGGCGAACAGTTAACGCT
GGTCATCGGGGTGGCCGCGAACGATCCGACCTCGGTGGCGGTCGCCAACACTGCTGCCGACCAGCTGCGCGACGTCGGCA
TCGCCGCGACTGTGCTGGCGTTAGACCCGGTCACGCTCTATCACGACGCGCTGAACGACAATCGGGTAGACGCCATTGTG
GGCTGGCGCCAAGCCGGCGGAAACCTGGCGACGCTGCTGGCCTCTCGTTACGGCTGTCCCGCATTGCAGGCGACGACGGT
CCCGGCTGCGAATGCGCCGACGACGGCCCCGTCCGCTCCCATTGGCCCTACGCCGTCCGCCGCGCCCGACACCGCGACAC
CGCCACCAACGGCGCCGCGCCGCCCATCCGACCCGGGCGCGCTGGTAAAAGCGCCGTCGAATCTCACCGGCATCTGCGAC
CGCAGCATCCAGTCGAACATCGATGCCGCACTCAATGGCACCAAGAACATCAACGACGTGATCACCGCGGTCGAACCGCG
ACTGTGGAATATGTCGACCGTGTTGCCGATCCTGCAGGACACCACGATCGTCGCGGCCGGCCCGAGCGTGCAGAACGTCA
GCCTGTCTGGTGCGGTGCCAGTGGGCATCGTCGGCGACGCCGGCCAATGGGTGAAGACCGGGCAATAG

Upstream 100 bases:

>100_bases
TAGCAACTTGGCGCGCTGGCCGCGCGAGCGTAACGCCACTGCGAAATCCAGCCCGGCTTTTCGCAGCCGGGTTACGCTCG
TGGGGGTACTGGATAGCCTG

Downstream 100 bases:

>100_bases
CCCTGGTCACGCCGGCGGAATCGTCGGCTAGCTCTCGCGGCGTTCGCCGGTGGTGAGGATCATGGCGTCGATAATGCGTG
TGAGCTGCTCACGGTCCGGC

Product: putative lipoprotein lpqW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MGVPSPVRRVCVTVGALVALACMVLAGCTVSPPPAPQSTDTPRSTPPPPRRPTQIIMGIDWIGPGFNPHLLSDLSPVNAA
ISALVLPSAFRPIPDPNTPTGSRWEMDPTLLVSADVTNNHPFTVTYKIRPEAQWTDNAPIAADDFWYLWQQMVTQPGVVD
PAGYHLITSVQSLEGGKQAVVTFAQPYPAWRELFTDILPAHIVKDIPGGFASGLARALPVTGGQFRVENIDPQRDEILIA
RNDRYWGPPSKPGIILFRRAGAPAALADSVRNGDTQVAQVHGGSAAFAQLSAIPDVRTARIVTPRVMQFTLRANVPKLAD
TQVRKAILGLLDVDLLAAVGAGTDNTVTLDQAQIRSPSDPGYVPTAPPAMSSAAALGLLEASGFQVDTNTSVSPAPSVPD
STTTSVSTGPPEVIRGRISKDGEQLTLVIGVAANDPTSVAVANTAADQLRDVGIAATVLALDPVTLYHDALNDNRVDAIV
GWRQAGGNLATLLASRYGCPALQATTVPAANAPTTAPSAPIGPTPSAAPDTATPPPTAPRRPSDPGALVKAPSNLTGICD
RSIQSNIDAALNGTKNINDVITAVEPRLWNMSTVLPILQDTTIVAAGPSVQNVSLSGAVPVGIVGDAGQWVKTGQ

Sequences:

>Translated_635_residues
MGVPSPVRRVCVTVGALVALACMVLAGCTVSPPPAPQSTDTPRSTPPPPRRPTQIIMGIDWIGPGFNPHLLSDLSPVNAA
ISALVLPSAFRPIPDPNTPTGSRWEMDPTLLVSADVTNNHPFTVTYKIRPEAQWTDNAPIAADDFWYLWQQMVTQPGVVD
PAGYHLITSVQSLEGGKQAVVTFAQPYPAWRELFTDILPAHIVKDIPGGFASGLARALPVTGGQFRVENIDPQRDEILIA
RNDRYWGPPSKPGIILFRRAGAPAALADSVRNGDTQVAQVHGGSAAFAQLSAIPDVRTARIVTPRVMQFTLRANVPKLAD
TQVRKAILGLLDVDLLAAVGAGTDNTVTLDQAQIRSPSDPGYVPTAPPAMSSAAALGLLEASGFQVDTNTSVSPAPSVPD
STTTSVSTGPPEVIRGRISKDGEQLTLVIGVAANDPTSVAVANTAADQLRDVGIAATVLALDPVTLYHDALNDNRVDAIV
GWRQAGGNLATLLASRYGCPALQATTVPAANAPTTAPSAPIGPTPSAAPDTATPPPTAPRRPSDPGALVKAPSNLTGICD
RSIQSNIDAALNGTKNINDVITAVEPRLWNMSTVLPILQDTTIVAAGPSVQNVSLSGAVPVGIVGDAGQWVKTGQ
>Mature_634_residues
GVPSPVRRVCVTVGALVALACMVLAGCTVSPPPAPQSTDTPRSTPPPPRRPTQIIMGIDWIGPGFNPHLLSDLSPVNAAI
SALVLPSAFRPIPDPNTPTGSRWEMDPTLLVSADVTNNHPFTVTYKIRPEAQWTDNAPIAADDFWYLWQQMVTQPGVVDP
AGYHLITSVQSLEGGKQAVVTFAQPYPAWRELFTDILPAHIVKDIPGGFASGLARALPVTGGQFRVENIDPQRDEILIAR
NDRYWGPPSKPGIILFRRAGAPAALADSVRNGDTQVAQVHGGSAAFAQLSAIPDVRTARIVTPRVMQFTLRANVPKLADT
QVRKAILGLLDVDLLAAVGAGTDNTVTLDQAQIRSPSDPGYVPTAPPAMSSAAALGLLEASGFQVDTNTSVSPAPSVPDS
TTTSVSTGPPEVIRGRISKDGEQLTLVIGVAANDPTSVAVANTAADQLRDVGIAATVLALDPVTLYHDALNDNRVDAIVG
WRQAGGNLATLLASRYGCPALQATTVPAANAPTTAPSAPIGPTPSAAPDTATPPPTAPRRPSDPGALVKAPSNLTGICDR
SIQSNIDAALNGTKNINDVITAVEPRLWNMSTVLPILQDTTIVAAGPSVQNVSLSGAVPVGIVGDAGQWVKTGQ

Specific function: May directly or indirectly regulate the accessibility of the key branch point intermediate, monoacyl phosphatidylinositol tetramannoside (AcPIM4), to the elongating alpha-1,6 mannosyltransferases which could regulate the lipoarabinomannans (LAMs) biosynth

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPQW_MYCTU (O50422)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842575
- PIR:   F70874
- RefSeq:   NP_215682.1
- RefSeq:   NP_335646.1
- ProteinModelPortal:   O50422
- SMR:   O50422
- EnsemblBacteria:   EBMYCT00000001307
- EnsemblBacteria:   EBMYCT00000071263
- GeneID:   886036
- GeneID:   924873
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1203
- KEGG:   mtu:Rv1166
- TIGR:   MT1203
- TubercuList:   Rv1166
- GeneTree:   EBGT00050000016139
- HOGENOM:   HBG564830
- OMA:   PRVMQLT
- ProtClustDB:   CLSK790992
- GO:   GO:0040007
- GO:   GO:0009405
- InterPro:   IPR000914

Pfam domain/function: PF00496 SBP_bac_5

EC number: NA

Molecular weight: Translated: 66131; Mature: 65999

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVPSPVRRVCVTVGALVALACMVLAGCTVSPPPAPQSTDTPRSTPPPPRRPTQIIMGID
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
WIGPGFNPHLLSDLSPVNAAISALVLPSAFRPIPDPNTPTGSRWEMDPTLLVSADVTNNH
ECCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEEECCCCC
PFTVTYKIRPEAQWTDNAPIAADDFWYLWQQMVTQPGVVDPAGYHLITSVQSLEGGKQAV
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEE
VTFAQPYPAWRELFTDILPAHIVKDIPGGFASGLARALPVTGGQFRVENIDPQRDEILIA
EEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEE
RNDRYWGPPSKPGIILFRRAGAPAALADSVRNGDTQVAQVHGGSAAFAQLSAIPDVRTAR
ECCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCCEE
IVTPRVMQFTLRANVPKLADTQVRKAILGLLDVDLLAAVGAGTDNTVTLDQAQIRSPSDP
ECCHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHCCCCCCC
GYVPTAPPAMSSAAALGLLEASGFQVDTNTSVSPAPSVPDSTTTSVSTGPPEVIRGRISK
CCCCCCCCHHHHHHHHHEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
DGEQLTLVIGVAANDPTSVAVANTAADQLRDVGIAATVLALDPVTLYHDALNDNRVDAIV
CCCEEEEEEEEECCCCCEEEEEHHHHHHHHHCCCEEEEEEECCHHHHHHHCCCCCEEEEE
GWRQAGGNLATLLASRYGCPALQATTVPAANAPTTAPSAPIGPTPSAAPDTATPPPTAPR
EHHHCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPSDPGALVKAPSNLTGICDRSIQSNIDAALNGTKNINDVITAVEPRLWNMSTVLPILQD
CCCCCCCEEECCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHCC
TTIVAAGPSVQNVSLSGAVPVGIVGDAGQWVKTGQ
CEEEEECCCCCEEEECCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
GVPSPVRRVCVTVGALVALACMVLAGCTVSPPPAPQSTDTPRSTPPPPRRPTQIIMGID
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
WIGPGFNPHLLSDLSPVNAAISALVLPSAFRPIPDPNTPTGSRWEMDPTLLVSADVTNNH
ECCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEEECCCCC
PFTVTYKIRPEAQWTDNAPIAADDFWYLWQQMVTQPGVVDPAGYHLITSVQSLEGGKQAV
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEE
VTFAQPYPAWRELFTDILPAHIVKDIPGGFASGLARALPVTGGQFRVENIDPQRDEILIA
EEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEE
RNDRYWGPPSKPGIILFRRAGAPAALADSVRNGDTQVAQVHGGSAAFAQLSAIPDVRTAR
ECCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCCEE
IVTPRVMQFTLRANVPKLADTQVRKAILGLLDVDLLAAVGAGTDNTVTLDQAQIRSPSDP
ECCHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHCCCCCCC
GYVPTAPPAMSSAAALGLLEASGFQVDTNTSVSPAPSVPDSTTTSVSTGPPEVIRGRISK
CCCCCCCCHHHHHHHHHEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
DGEQLTLVIGVAANDPTSVAVANTAADQLRDVGIAATVLALDPVTLYHDALNDNRVDAIV
CCCEEEEEEEEECCCCCEEEEEHHHHHHHHHCCCEEEEEEECCHHHHHHHCCCCCEEEEE
GWRQAGGNLATLLASRYGCPALQATTVPAANAPTTAPSAPIGPTPSAAPDTATPPPTAPR
EHHHCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPSDPGALVKAPSNLTGICDRSIQSNIDAALNGTKNINDVITAVEPRLWNMSTVLPILQD
CCCCCCCEEECCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHCC
TTIVAAGPSVQNVSLSGAVPVGIVGDAGQWVKTGQ
CEEEEECCCCCEEEECCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036