Click here to switch to the map view.

The map label for this gene is degQ [H]

Identifier: 121636910

GI number: 121636910

Start: 1129555

End: 1130949

Strand: Direct

Name: degQ [H]

Synonym: BCG_1038

Alternate gene names: 121636910

Gene position: 1129555-1130949 (Clockwise)

Preceding gene: 121636909

Following gene: 121636911

Centisome position: 25.82

GC content: 66.74

Gene sequence:

>1395_bases
ATGGCCAAGTTGGCCCGAGTAGTGGGCCTAGTACAGGAAGAGCAACCTAGCGACATGACGAATCACCCACGGTATTCGCC
ACCGCCGCAGCAGCCGGGAACCCCAGGTTATGCTCAGGGGCAGCAGCAAACGTACAGCCAGCAGTTCGACTGGCGTTACC
CACCGTCCCCGCCCCCGCAGCCAACCCAGTACCGTCAACCCTACGAGGCGTTGGGTGGTACCCGGCCGGGTCTGATACCT
GGCGTGATTCCGACCATGACGCCCCCTCCTGGGATGGTTCGCCAACGCCCTCGTGCAGGCATGTTGGCCATCGGCGCGGT
GACGATAGCGGTGGTGTCCGCCGGCATCGGCGGCGCGGCCGCATCCCTGGTCGGGTTCAACCGGGCACCCGCCGGCCCCA
GCGGCGGCCCAGTGGCTGCCAGCGCGGCGCCAAGCATCCCCGCAGCAAACATGCCGCCGGGGTCGGTCGAACAGGTGGCG
GCCAAGGTGGTGCCCAGTGTCGTCATGTTGGAAACCGATCTGGGCCGCCAGTCGGAGGAGGGCTCCGGCATCATTCTGTC
TGCCGAGGGGCTGATCTTGACCAACAACCACGTGATCGCGGCGGCCGCCAAGCCTCCCCTGGGCAGTCCGCCGCCGAAAA
CGACGGTAACCTTCTCTGACGGGCGGACCGCACCCTTCACGGTGGTGGGGGCTGACCCCACCAGTGATATCGCCGTCGTC
CGTGTTCAGGGCGTCTCCGGGCTCACCCCGATCTCCCTGGGTTCCTCCTCGGACCTGAGGGTCGGTCAGCCGGTGCTGGC
GATCGGGTCGCCGCTCGGTTTGGAGGGCACCGTGACCACGGGGATCGTCAGCGCTCTCAACCGTCCAGTGTCGACGACCG
GCGAGGCCGGCAACCAGAACACCGTGCTGGACGCCATTCAGACCGACGCCGCGATCAACCCCGGTAACTCCGGGGGCGCG
CTGGTGAACATGAACGCTCAACTCGTCGGAGTCAACTCGGCCATTGCCACGCTGGGCGCGGACTCAGCCGATGCGCAGAG
CGGCTCGATCGGTCTCGGTTTTGCGATTCCAGTCGACCAGGCCAAGCGCATCGCCGACGAGTTGATCAGCACCGGCAAGG
CGTCACATGCCTCCCTGGGTGTGCAGGTGACCAATGACAAAGACACCCCGGGCGCCAAGATCGTCGAAGTAGTGGCCGGT
GGTGCTGCCGCGAACGCTGGAGTGCCGAAGGGCGTCGTTGTCACCAAGGTCGACGACCGCCCGATCAACAGCGCGGACGC
GTTGGTTGCCGCCGTGCGGTCCAAAGCGCCGGGCGCCACGGTGGCGCTAACCTTTCAGGATCCCTCGGGCGGTAGCCGCA
CAGTGCAAGTCACCCTCGGCAAGGCGGAGCAGTGA

Upstream 100 bases:

>100_bases
TCTCGGGGTTCGGCGAACGTTATCTCAGTGGAATCTCAGTCCACGCGCGCAACCTAGTTGTGCAGTTACTGTTGAAAGCC
ACACCCATGCCAGTCCACGC

Downstream 100 bases:

>100_bases
TGAAGGTCGCCGCGCAGTGTTCAAAGCTCGGATATACGGTGGCACCCATGGAACAGCGTGCGGAGTTGGTGGTTGGCCGG
GCACTTGTCGTCGTCGTTGA

Product: putative serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MAKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQPTQYRQPYEALGGTRPGLIP
GVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAAASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVA
AKVVPSVVMLETDLGRQSEEGSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVV
RVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGA
LVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQAKRIADELISTGKASHASLGVQVTNDKDTPGAKIVEVVAG
GAAANAGVPKGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTLGKAEQ

Sequences:

>Translated_464_residues
MAKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQPTQYRQPYEALGGTRPGLIP
GVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAAASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVA
AKVVPSVVMLETDLGRQSEEGSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVV
RVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGA
LVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQAKRIADELISTGKASHASLGVQVTNDKDTPGAKIVEVVAG
GAAANAGVPKGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTLGKAEQ
>Mature_463_residues
AKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQPTQYRQPYEALGGTRPGLIPG
VIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAAASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVAA
KVVPSVVMLETDLGRQSEEGSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVVR
VQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGAL
VNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQAKRIADELISTGKASHASLGVQVTNDKDTPGAKIVEVVAGG
AAANAGVPKGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTLGKAEQ

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=307, Percent_Identity=33.2247557003257, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI4506141, Length=309, Percent_Identity=31.3915857605178, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7019477, Length=314, Percent_Identity=30.8917197452229, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI24308541, Length=307, Percent_Identity=32.2475570032573, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1789629, Length=290, Percent_Identity=39.3103448275862, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786356, Length=274, Percent_Identity=39.4160583941606, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789630, Length=337, Percent_Identity=32.6409495548961, Blast_Score=128, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24646839, Length=325, Percent_Identity=33.2307692307692, Blast_Score=135, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 46437; Mature: 46306

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQ
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
PTQYRQPYEALGGTRPGLIPGVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAA
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHCCCCHHH
ASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVAAKVVPSVVMLETDLGRQSEE
HHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCC
GSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVV
CCEEEEEECCEEEECCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCEEEE
RVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQN
EEECCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
TVLDAIQTDAAINPGNSGGALVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQ
HHHHHHHCCCCCCCCCCCCEEEECCEEEEECCHHHHHCCCCCCCCCCCCEEEEEECCHHH
AKRIADELISTGKASHASLGVQVTNDKDTPGAKIVEVVAGGAAANAGVPKGVVVTKVDDR
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHEEEEEECCCCCCCCCCCCEEEEECCCC
PINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTLGKAEQ
CCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
AKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
PTQYRQPYEALGGTRPGLIPGVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAA
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHCCCCHHH
ASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVAAKVVPSVVMLETDLGRQSEE
HHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCC
GSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVV
CCEEEEEECCEEEECCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCEEEE
RVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQN
EEECCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
TVLDAIQTDAAINPGNSGGALVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQ
HHHHHHHCCCCCCCCCCCCEEEECCEEEEECCHHHHHCCCCCCCCCCCCEEEEEECCHHH
AKRIADELISTGKASHASLGVQVTNDKDTPGAKIVEVVAGGAAANAGVPKGVVVTKVDDR
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHEEEEEECCCCCCCCCCCCEEEEECCCC
PINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTLGKAEQ
CCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]