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The map label for this gene is moaB2 [H]

Identifier: 121636911

GI number: 121636911

Start: 1130949

End: 1131494

Strand: Direct

Name: moaB2 [H]

Synonym: BCG_1039

Alternate gene names: 121636911

Gene position: 1130949-1131494 (Clockwise)

Preceding gene: 121636910

Following gene: 121636913

Centisome position: 25.85

GC content: 66.3

Gene sequence:

>546_bases
ATGAAGGTCGCCGCGCAGTGTTCAAAGCTCGGATATACGGTGGCACCCATGGAACAGCGTGCGGAGTTGGTGGTTGGCCG
GGCACTTGTCGTCGTCGTTGACGATCGCACGGCGCACGGCGATGAAGACCACAGCGGGCCGCTTGTCACCGAGCTGCTCA
CCGAGGCCGGGTTTGTTGTCGACGGCGTGGTGGCGGTGTCGGCCGACGAGGTCGAGATCCGAAATGCGCTGAACACAGCG
GTGATCGGCGGGGTGGACCTGGTGGTGTCGGTCGGCGGGACCGGGGTGACGCCTCGCGATGTCACCCCGGAAGCCACCCG
CGACATTCTGGACCGCGAGATCCTCGGTATCGCCGAGGCCATCCGCGCGTCCGGGCTGTCCGCGGGAATCGTCGACGCCG
GGTTGTCGCGCGGCCTGGCGGGTGTCTCCGGCAGCACGCTGGTGGTCAACCTCGCGGGTTCGCGTTATGCGGTGCGCGAT
GGAATGGCGACGCTGAATCCGCTAGCGGCACAGATCATCGGGCAGTTGTCGAGCTTGGAGATCTGA

Upstream 100 bases:

>100_bases
TGCGGTCCAAAGCGCCGGGCGCCACGGTGGCGCTAACCTTTCAGGATCCCTCGGGCGGTAGCCGCACAGTGCAAGTCACC
CTCGGCAAGGCGGAGCAGTG

Downstream 100 bases:

>100_bases
ATCCGGATCGAGTGTCGGGCTATTGCGATTCTGTGCTCGCGAGAGGCCCGTCGGTTGGCGATGGTGTCCCACGGCCGCCG
TGCCTCCCCGGCGAGTCCCC

Product: putative pterin-4-alpha-carbinolamine dehydratase moaB2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKVAAQCSKLGYTVAPMEQRAELVVGRALVVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGVVAVSADEVEIRNALNTA
VIGGVDLVVSVGGTGVTPRDVTPEATRDILDREILGIAEAIRASGLSAGIVDAGLSRGLAGVSGSTLVVNLAGSRYAVRD
GMATLNPLAAQIIGQLSSLEI

Sequences:

>Translated_181_residues
MKVAAQCSKLGYTVAPMEQRAELVVGRALVVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGVVAVSADEVEIRNALNTA
VIGGVDLVVSVGGTGVTPRDVTPEATRDILDREILGIAEAIRASGLSAGIVDAGLSRGLAGVSGSTLVVNLAGSRYAVRD
GMATLNPLAAQIIGQLSSLEI
>Mature_181_residues
MKVAAQCSKLGYTVAPMEQRAELVVGRALVVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGVVAVSADEVEIRNALNTA
VIGGVDLVVSVGGTGVTPRDVTPEATRDILDREILGIAEAIRASGLSAGIVDAGLSRGLAGVSGSTLVVNLAGSRYAVRD
GMATLNPLAAQIIGQLSSLEI

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=130, Percent_Identity=33.0769230769231, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI10880983, Length=139, Percent_Identity=32.3741007194245, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564954, Length=162, Percent_Identity=35.1851851851852, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136978, Length=144, Percent_Identity=35.4166666666667, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24638841, Length=144, Percent_Identity=35.4166666666667, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18441; Mature: 18441

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAAQCSKLGYTVAPMEQRAELVVGRALVVVVDDRTAHGDEDHSGPLVTELLTEAGFVV
CCCHHHHHHCCCEECCHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCEE
DGVVAVSADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILDREILGIAEA
CCEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IRASGLSAGIVDAGLSRGLAGVSGSTLVVNLAGSRYAVRDGMATLNPLAAQIIGQLSSLE
HHHCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCEEEHHCCCHHHHHHHHHHHHHHHHCC
I
C
>Mature Secondary Structure
MKVAAQCSKLGYTVAPMEQRAELVVGRALVVVVDDRTAHGDEDHSGPLVTELLTEAGFVV
CCCHHHHHHCCCEECCHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCEE
DGVVAVSADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILDREILGIAEA
CCEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IRASGLSAGIVDAGLSRGLAGVSGSTLVVNLAGSRYAVRDGMATLNPLAAQIIGQLSSLE
HHHCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCEEEHHCCCHHHHHHHHHHHHHHHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]