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The map label for this gene is pknDb [H]

Identifier: 121636854

GI number: 121636854

Start: 1068395

End: 1069504

Strand: Reverse

Name: pknDb [H]

Synonym: BCG_0983c

Alternate gene names: 121636854

Gene position: 1069504-1068395 (Counterclockwise)

Preceding gene: 121636855

Following gene: 121636850

Centisome position: 24.45

GC content: 66.49

Gene sequence:

>1110_bases
TTGCTGGCCACTCCGGCCGATACGGGCTTGAGCCAGTCCGAGTCCGGCATTGCCGGGGCGGGCACCGGCCCACCGACCCC
GGGTGCTGCCCGATGGTCGCCCGGGGACTCCGCGACCGTGGCCGGACCCCTGGCAGCGGACAGCCGCGGCGGGAACTGGC
CCAGCCAAACCGGACACTCCCCTGCCGTCCCGAATGCGCTCCAGGCCTCCCTGGGACACGCTGTGCCGCCGGCCGGCAAC
AAACGGAAGGTGTGGGCCGTCGTCGGCGCTGCCGCGATCGTACTGGTGGCCATCGTCGCCGCCGCCGGCTACCTGGTCTT
ACGACCTTCGTGGTCGCCGACGCAGGCATCCGGACAGACCGTGTTGCCGTTCACCGGCATCGACTTCCGCCTCTCGCCGA
GTGGGGTGGCAGTGGACAGCGCCGGCAACGTGTACGTCACCAGTGAGGGCATGTACGGCCGAGTGGTCAAGTTGGCCACC
GGGTCAACCGGCACGACGGTGTTACCGTTCAACGGGCTGTACCAGCCGCAGGGGTTGGCGGTGGACGGCGCTGGCACCGT
ATACGTCACCGATTTCAACAACCGGGTGGTGACGTTAGCGGCCGGGTCCAACAACCAGACCGTGCTACCGTTCGACGGCC
TCAACTACCCCGAAGGTCTCGCGGTGGATACCCAGGGTGCGGTATACGTCGCCGACCGGGGCAACAACAGGGTGGTGAAG
TTGGCGGCCGGATCCAAGACCCAGACCGTGCTGCCGTTCACCGGCCTCAACGACCCCGACGGGGTGGCCGTCGACAACTC
CGGCAACGTCTATGTCACCGACACCGACAACAACAGGGTTGTCAAGCTAGAGGCCGAGTCGAATAACCAGGTCGTGCTGC
CATTCACGGATATCACCGCACCGTGGGGCATCGCGGTGGACGAAGCCGGAACCGTCTACGTCACCGAGCACAACACAAAC
CAGGTGGTCAAACTCCTGGCCGGGTCGACCACCTCGACAGTGCTACCGTTCACCGGCCTCAACACCCCCCTCGCGGTGGC
AGTGGACAGCGACCGGACCGTCTACGTCGCCGACCGCGGCAACGACCGAGTGGTGAAACTCACGTCATAA

Upstream 100 bases:

>100_bases
ATGAGCGCTGGTGATCTGGCCATCGCCGCCCATGACGCACTCAACCACATCCGAGCAACACCAGGCCACGACGATTCTGC
GGCGCGGTGACAACGCAACC

Downstream 100 bases:

>100_bases
CGGGAGTCACCGCCGTCGGGTTGCGACGAACCGGATCATCGCCGCGGCCAGGTTGATCGTGGCGACCACGATGATCAGGG
TCAGCGCCGCGCCCCAGACG

Product: transmembrane serine/threonine-protein kinase D pknDb

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MLATPADTGLSQSESGIAGAGTGPPTPGAARWSPGDSATVAGPLAADSRGGNWPSQTGHSPAVPNALQASLGHAVPPAGN
KRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTGIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLAT
GSTGTTVLPFNGLYQPQGLAVDGAGTVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVK
LAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAGTVYVTEHNTN
QVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKLTS

Sequences:

>Translated_369_residues
MLATPADTGLSQSESGIAGAGTGPPTPGAARWSPGDSATVAGPLAADSRGGNWPSQTGHSPAVPNALQASLGHAVPPAGN
KRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTGIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLAT
GSTGTTVLPFNGLYQPQGLAVDGAGTVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVK
LAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAGTVYVTEHNTN
QVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKLTS
>Mature_369_residues
MLATPADTGLSQSESGIAGAGTGPPTPGAARWSPGDSATVAGPLAADSRGGNWPSQTGHSPAVPNALQASLGHAVPPAGN
KRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTGIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLAT
GSTGTTVLPFNGLYQPQGLAVDGAGTVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVK
LAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAGTVYVTEHNTN
QVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKLTS

Specific function: Unknown

COG id: COG3391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI84993742, Length=265, Percent_Identity=24.1509433962264, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011009
- InterPro:   IPR001258
- InterPro:   IPR013017
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF01436 NHL; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 37670; Mature: 37670

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS51125 NHL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLATPADTGLSQSESGIAGAGTGPPTPGAARWSPGDSATVAGPLAADSRGGNWPSQTGHS
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
PAVPNALQASLGHAVPPAGNKRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQT
CCCCHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCE
VLPFTGIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLA
EEEECCCCEEECCCCEEEECCCCEEEECCCCCEEEEEEEECCCCCEEEECCCCCCCCCEE
VDGAGTVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVK
ECCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCCEEEECCCEEEEEECCCCEEEE
LAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITA
EECCCCCEEEEEECCCCCCCCEEEECCCCEEEEECCCCEEEEEEECCCCEEEEEEECCCC
PWGIAVDEAGTVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRG
CCCEEECCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCCCCEEEEECCCCEEEEEECC
NDRVVKLTS
CCEEEEEEC
>Mature Secondary Structure
MLATPADTGLSQSESGIAGAGTGPPTPGAARWSPGDSATVAGPLAADSRGGNWPSQTGHS
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
PAVPNALQASLGHAVPPAGNKRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQT
CCCCHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCE
VLPFTGIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLA
EEEECCCCEEECCCCEEEECCCCEEEECCCCCEEEEEEEECCCCCEEEECCCCCCCCCEE
VDGAGTVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVK
ECCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCCEEEECCCEEEEEECCCCEEEE
LAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITA
EECCCCCEEEEEECCCCCCCCEEEECCCCEEEEECCCCEEEEEEECCCCEEEEEEECCCC
PWGIAVDEAGTVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRG
CCCEEECCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCCCCEEEEECCCCEEEEEECC
NDRVVKLTS
CCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9119030; 9634230; 12218036 [H]