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The map label for this gene is cfp29 [H]

Identifier: 121636722

GI number: 121636722

Start: 921894

End: 922691

Strand: Reverse

Name: cfp29 [H]

Synonym: BCG_0850c

Alternate gene names: 121636722

Gene position: 922691-921894 (Counterclockwise)

Preceding gene: 121636723

Following gene: 121636720

Centisome position: 21.09

GC content: 62.78

Gene sequence:

>798_bases
ATGAACAATCTCTACCGCGATTTGGCACCGGTCACCGAAGCCGCTTGGGCGGAAATCGAATTGGAGGCGGCGCGGACGTT
CAAGCGACACATCGCCGGGCGCCGGGTGGTCGATGTCAGTGATCCCGGGGGGCCCGTCACCGCGGCGGTCAGCACCGGCC
GGCTGATCGATGTTAAGGCACCAACCAACGGCGTGATCGCCCACCTGCGGGCCAGCAAACCCCTTGTCCGGCTACGGGTT
CCGTTTACCCTGTCGCGCAACGAGATCGACGACGTGGAACGTGGCTCTAAGGACTCCGATTGGGAACCGGTAAAGGAGGC
GGCCAAGAAGCTGGCCTTCGTCGAGGACCGCACAATATTCGAAGGCTACAGCGCCGCATCAATCGAAGGGATCCGCAGCG
CGAGTTCGAACCCGGCGCTGACGTTGCCCGAGGATCCCCGTGAAATCCCTGATGTCATCTCCCAGGCATTGTCCGAACTG
CGGTTGGCCGGTGTGGACGGACCGTATTCGGTGTTGCTCTCTGCTGACGTCTACACCAAGGTTAGCGAGACTTCCGATCA
CGGCTATCCCATCCGTGAGCATCTGAACCGGCTGGTGGACGGGGACATCATTTGGGCCCCGGCCATCGACGGCGCGTTCG
TGCTGACCACTCGAGGCGGCGACTTCGACCTACAGCTGGGCACCGACGTTGCAATCGGGTACGCCAGCCACGACACGGAC
ACCGTGCGCCTCTACCTGCAGGAGACGCTGACGTTCCTTTGCTACACCGCCGAGGCGTCGGTCGCGCTCAGCCACTAA

Upstream 100 bases:

>100_bases
CCATCGACTTTCTCGACCATCCACCGCCCCTACCGCAGGCGGCGACGCCAACTCTGGCAGCCGGGTCGCTATCGATCGGC
AGCTTGAAAGGAAGCCCCCG

Downstream 100 bases:

>100_bases
GGCACGAGCGCGAGCAATAGCTCCTATGGCAAGCGGCCGCGGGTTGGGTGTGTTCGGAGCTGGGCTGATGGACGGTGCGC
AGGGCCTGGAAGACGGTGCG

Product: 29 kDa antigen cfp29

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKAPTNGVIAHLRASKPLVRLRV
PFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIFEGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSEL
RLAGVDGPYSVLLSADVYTKVSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTD
TVRLYLQETLTFLCYTAEASVALSH

Sequences:

>Translated_265_residues
MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKAPTNGVIAHLRASKPLVRLRV
PFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIFEGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSEL
RLAGVDGPYSVLLSADVYTKVSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTD
TVRLYLQETLTFLCYTAEASVALSH
>Mature_265_residues
MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKAPTNGVIAHLRASKPLVRLRV
PFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIFEGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSEL
RLAGVDGPYSVLLSADVYTKVSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTD
TVRLYLQETLTFLCYTAEASVALSH

Specific function: Bacteriocin that has antimicrobial activity against a wide range of Gram-positive bacteria, including L.monocytogenes, B.cereus and S.aureus. May have a protease activity [H]

COG id: COG1659

COG function: function code S; Uncharacterized protein, linocin/CFP29 homolog

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007544 [H]

Pfam domain/function: PF04454 Linocin_M18 [H]

EC number: NA

Molecular weight: Translated: 28831; Mature: 28831

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKA
CCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCEEEEEEC
PTNGVIAHLRASKPLVRLRVPFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIF
CCCCEEEEEECCCCEEEEEECEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHC
EGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSELRLAGVDGPYSVLLSADVYTK
CCCCCHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHEE
VSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTD
ECCCCCCCCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCCEEEEECCCEEEEEECCCCC
TVRLYLQETLTFLCYTAEASVALSH
CEEHHHHHHHHEEEEECCCEEEECC
>Mature Secondary Structure
MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKA
CCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCEEEEEEC
PTNGVIAHLRASKPLVRLRVPFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIF
CCCCEEEEEECCCCEEEEEECEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHC
EGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSELRLAGVDGPYSVLLSADVYTK
CCCCCHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHEE
VSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTD
ECCCCCCCCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCCEEEEECCCEEEEEECCCCC
TVRLYLQETLTFLCYTAEASVALSH
CEEHHHHHHHHEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8919789 [H]