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The map label for this gene is pkn1 [H]

Identifier: 120613095

GI number: 120613095

Start: 4957315

End: 4958487

Strand: Reverse

Name: pkn1 [H]

Synonym: Aave_4459

Alternate gene names: 120613095

Gene position: 4958487-4957315 (Counterclockwise)

Preceding gene: 120613096

Following gene: 120613093

Centisome position: 92.63

GC content: 72.63

Gene sequence:

>1173_bases
ATGCCGCTAGCCATTCGCCGTCTGCGTCTGCCGTTGCCTTTGCCTGCCTTGCTGCCTGTGGCGTCGCCGTCGCCGATGCC
GTTGCGGCCGTCGCGGTGGCCATCATCCGGGCGCGCCACCGCTGCCATTGCCCTGCTGTCACTGCCCGCACTGTCGCCCG
CGGCCCTCGCTGCGGGCCCGGCGCCGGCCCCTTCGGCCGCTCCCGCCGTGTGGACCAATTCCCTGGGCATGCCATTCGTG
CGCGTGCCCGCGGGCAGTTTCCGGATGGGCAGCGACGAGTCGGTGAAGCACCTCGCGCGTGACTACCCGGGCATGGAGGC
GGGCCGGCTATCGGCCCTGGCCGACGAGGCGCCCGTGCACACCGTGCGCATCACCCGCGCGTTCTACCTGGGGCAGACGG
AAGTCACGGTGGGGCAGTTCCGGCGGTTCGTCGAAGCCTCGGGCTACCGCGCCGAGTCCGATGCCGACGGCACGGGCGGC
TACGGCTACAACCCTGCCTACGATCCCGACAAAAGCGCACGCGGCGATGCCTTCGAGGGGCGCAGCCCGCGCTATTCGTG
GCGATACCCGGGCTTCGCGCAGGGCGACGACCATCCCGTGGTGAACATCACGTGGCACGACGCGCACGCCATGGCGGCCT
GGCTGAGCGCCACCGAAGGCCACCGCTACCGGCTGCCGACCGAGGCCGAATGGGAATACGCCTGCCGCGCCGGCAAGGCC
GCGCGCTACGGGCACGGGAACGACCCCGCGGCGCTCCCGCGCCACGCCAACACCTTCGACCAGGCCGCCGCTCCCTACTG
GCCGCGCTGGCAGGCCCAGGCCGTGCCGGGCCATGACGGCCATGCGTTCACCGCGCCGGTGGCGGGCTACCCGGCCAATG
CCTTCGGACTGCACGACATGTCTGGCAACGTATGGGAATGGGTGTCCGACTGGCATGCCGACGATGCCTACGCCCGGTCG
GCGCGCGACGATCCGCAGGGCCCCGCCACGGGCACGGTGCGCGTGCGCCGCGGCGGCTCGTGGCACACGTGGCCGCTGTA
CGCGCGCTGCACGTACCGCAACTGGAACAGCCCGGAGACGCGGTACACGCTGGTGGGCATGCGTCTGGTCCGGGAGCTGG
ATGCCCCGCCCGGCGAACCCGGCTCCGGAGCGGTCAGGCGCGCCGCGCGGTGA

Upstream 100 bases:

>100_bases
GCAGAGGAGGCGGTGAGGGGGCGGCCAGACATCCCTACACTGGCGGATCTTCGCGAGGCGCCATTCGCCGCCGCGATTCG
CCCGTTGCTGGAGAGCCCGC

Downstream 100 bases:

>100_bases
CCGCCGCCATGCCCGCCAGGGCGATCAGCAGCGCGCCATATCCCAGCGCCGTGGCGTGCAGCCCGTACAGGCCCGCGAGC
AGGCCGGCCGCGATGGCGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPLAIRRLRLPLPLPALLPVASPSPMPLRPSRWPSSGRATAAIALLSLPALSPAALAAGPAPAPSAAPAVWTNSLGMPFV
RVPAGSFRMGSDESVKHLARDYPGMEAGRLSALADEAPVHTVRITRAFYLGQTEVTVGQFRRFVEASGYRAESDADGTGG
YGYNPAYDPDKSARGDAFEGRSPRYSWRYPGFAQGDDHPVVNITWHDAHAMAAWLSATEGHRYRLPTEAEWEYACRAGKA
ARYGHGNDPAALPRHANTFDQAAAPYWPRWQAQAVPGHDGHAFTAPVAGYPANAFGLHDMSGNVWEWVSDWHADDAYARS
ARDDPQGPATGTVRVRRGGSWHTWPLYARCTYRNWNSPETRYTLVGMRLVRELDAPPGEPGSGAVRRAAR

Sequences:

>Translated_390_residues
MPLAIRRLRLPLPLPALLPVASPSPMPLRPSRWPSSGRATAAIALLSLPALSPAALAAGPAPAPSAAPAVWTNSLGMPFV
RVPAGSFRMGSDESVKHLARDYPGMEAGRLSALADEAPVHTVRITRAFYLGQTEVTVGQFRRFVEASGYRAESDADGTGG
YGYNPAYDPDKSARGDAFEGRSPRYSWRYPGFAQGDDHPVVNITWHDAHAMAAWLSATEGHRYRLPTEAEWEYACRAGKA
ARYGHGNDPAALPRHANTFDQAAAPYWPRWQAQAVPGHDGHAFTAPVAGYPANAFGLHDMSGNVWEWVSDWHADDAYARS
ARDDPQGPATGTVRVRRGGSWHTWPLYARCTYRNWNSPETRYTLVGMRLVRELDAPPGEPGSGAVRRAAR
>Mature_389_residues
PLAIRRLRLPLPLPALLPVASPSPMPLRPSRWPSSGRATAAIALLSLPALSPAALAAGPAPAPSAAPAVWTNSLGMPFVR
VPAGSFRMGSDESVKHLARDYPGMEAGRLSALADEAPVHTVRITRAFYLGQTEVTVGQFRRFVEASGYRAESDADGTGGY
GYNPAYDPDKSARGDAFEGRSPRYSWRYPGFAQGDDHPVVNITWHDAHAMAAWLSATEGHRYRLPTEAEWEYACRAGKAA
RYGHGNDPAALPRHANTFDQAAAPYWPRWQAQAVPGHDGHAFTAPVAGYPANAFGLHDMSGNVWEWVSDWHADDAYARSA
RDDPQGPATGTVRVRRGGSWHTWPLYARCTYRNWNSPETRYTLVGMRLVRELDAPPGEPGSGAVRRAAR

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=302, Percent_Identity=32.1192052980132, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI38202250, Length=308, Percent_Identity=30.5194805194805, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI257470977, Length=247, Percent_Identity=31.1740890688259, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI194248088, Length=330, Percent_Identity=29.0909090909091, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI194248087, Length=319, Percent_Identity=28.5266457680251, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226437577, Length=208, Percent_Identity=33.1730769230769, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20130397, Length=310, Percent_Identity=28.7096774193548, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 42411; Mature: 42279

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLAIRRLRLPLPLPALLPVASPSPMPLRPSRWPSSGRATAAIALLSLPALSPAALAAGP
CCCCCEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHEEHHHHCCCCCHHHHHCCC
APAPSAAPAVWTNSLGMPFVRVPAGSFRMGSDESVKHLARDYPGMEAGRLSALADEAPVH
CCCCCCCCCEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCE
TVRITRAFYLGQTEVTVGQFRRFVEASGYRAESDADGTGGYGYNPAYDPDKSARGDAFEG
EEEEEEEEEECCCEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RSPRYSWRYPGFAQGDDHPVVNITWHDAHAMAAWLSATEGHRYRLPTEAEWEYACRAGKA
CCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCCCCHHHHHHCCCC
ARYGHGNDPAALPRHANTFDQAAAPYWPRWQAQAVPGHDGHAFTAPVAGYPANAFGLHDM
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEECCCCCCCCEEECCCCCCCCCCCCCCCC
SGNVWEWVSDWHADDAYARSARDDPQGPATGTVRVRRGGSWHTWPLYARCTYRNWNSPET
CCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCC
RYTLVGMRLVRELDAPPGEPGSGAVRRAAR
EEHHHHHHHHHHHCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
PLAIRRLRLPLPLPALLPVASPSPMPLRPSRWPSSGRATAAIALLSLPALSPAALAAGP
CCCCEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHEEHHHHCCCCCHHHHHCCC
APAPSAAPAVWTNSLGMPFVRVPAGSFRMGSDESVKHLARDYPGMEAGRLSALADEAPVH
CCCCCCCCCEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCE
TVRITRAFYLGQTEVTVGQFRRFVEASGYRAESDADGTGGYGYNPAYDPDKSARGDAFEG
EEEEEEEEEECCCEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RSPRYSWRYPGFAQGDDHPVVNITWHDAHAMAAWLSATEGHRYRLPTEAEWEYACRAGKA
CCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCCCCHHHHHHCCCC
ARYGHGNDPAALPRHANTFDQAAAPYWPRWQAQAVPGHDGHAFTAPVAGYPANAFGLHDM
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEECCCCCCCCEEECCCCCCCCCCCCCCCC
SGNVWEWVSDWHADDAYARSARDDPQGPATGTVRVRRGGSWHTWPLYARCTYRNWNSPET
CCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCC
RYTLVGMRLVRELDAPPGEPGSGAVRRAAR
EEHHHHHHHHHHHCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]