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The map label for this gene is dsbD [H]

Identifier: 120613092

GI number: 120613092

Start: 4953069

End: 4955336

Strand: Direct

Name: dsbD [H]

Synonym: Aave_4456

Alternate gene names: 120613092

Gene position: 4953069-4955336 (Clockwise)

Preceding gene: 120613091

Following gene: 120613094

Centisome position: 92.53

GC content: 74.65

Gene sequence:

>2268_bases
ATGTCCGTCCGCCTCCTGCAGCGCCTGCTGCCGTCCTTCGCCCTCCTGGCCGCCTGCGCCCTGGGAGCGCCGGCTTCCGC
CCAGCTGCTGTCCGAGCCCGCTGCCGGCATCTCCGGCGGCACGCCGGCCGGCAGCAGCACCGTCACCACGCCGCACGTGC
GCGCCGAGCTGGTGGCGCACGCCCCCGACGGCGTGGGTCCGGGCAAGCCGCTCTGGCTGGGCCTGTCGATCACGCACCAG
CCCGAGTGGCACACCTACTGGAAGAACCCGGGCGACTCCGGCCTGCCCACGCAGATCGAATGGCGCCAGCTGCCGCCGGG
CATCGACGCCGGAGAGATCGCCTGGCCCGTGCCGCGCAAGATCCCCATCGGCACCCTGGCCAACTACGGCTACGAAGGCA
CGGTGCTGCTGCCCGTGCCCATGACCGTCTCGGGCGCGTTCTCGCCCGGGCCGCTCGCGCGCAATGCCACCTTCACCCTC
CATGCCTCCTGGCTGGTCTGCCGCAAGGAGTGCATCCCCGAAGAAGGCACCTTCACCCTGCAGGTGCCCATCGCCAGCAC
CACCGCCATGCAGGCGCAGGATTTCGAGGCGGCGCGCCAGGCCCATCCGCAGCCGCTGTCCCTTCCGGCCGCCGCGGCCG
CCGGCGGCACCCGCAGCCATGCGCGGGTGGATCGCGGCATGCTGGTGCTCACCGTCGCCGGCCTGCCCGAGGCGGTGCGC
GGCAAGCCGATGGACTTCTTCCCCGAAACGCCCGGCATCATCGAAACCGCCGACGACGGCACGCAGGACTGGCAGGGCGA
CGTCTGGACCGCGCGCATGCCCCTTTCCGCCCAGCGCAGCGAAGGCCCCATGTCCCTGCCCGTCGTGCTCGCGCAGGGCG
GCCGGGGCTGGCGCGCCGAACTCCCCGTGGAAGGCGGCTGGCCCCGGCCGGCGTCCCTCGCCACCGTCTCGCCCGCGCTG
GAAGCCGCGCTGCGCGCGAATGCGCAGCAGGCCGCGCAGGCGCTCCCAGCCGCGGCCACCCCGGCCCCGGCCGGCGCACT
GGCGGCCGCGCTGTTGGGCGCCCTGCTCGGCGGGCTGGTACTCAACCTCATGCCCTGCGTGTTCCCGGTGCTCGCCATCA
AGGTGGCCGGGTTCGCGCGCCACGGGCAGGACCGCCGCGCCCACCGGCTGGGCGGCATCGCCTACACGGCCGGCGTGGTG
CTCTCCTTCCTGGCCCTGGGCGGCGCCATGCTGGCGCTGCGCGCGGCCGGCGAAGCGGTGGGCTGGGGCTTCCAGCTGCA
GTCGCCCGCCGTGGTGGCGGTGCTGGCCGCGCTGTTCACGCTGATCGGCCTCAACCTCTCCGGCATGTTCGAGTTCGGCC
GCATGCTGCCCTCCTCCCTCGCCGGCCTGCAGGCGCGCCACCCCGCGGCCGACGCCTTCCTGACCGGCGTGCTGGCCGTG
GCCGTGGCATCCCCCTGCACCGCCCCCTTCATGGGCGCCTCGGTCGGCCTCACGGCCACGCTGCCGGCCGCGCAGGCGCT
GGCGGTGTTCGCCGCGCTCGGCGTCGGCCTGGCCCTGCCCTACCTCGCCGCGAGCTGGGTGCCCGCCGTCGCCCGCGCCC
TGCCCCGCCCCGGCGCCTGGATGGACACGCTGCGCCGCTTCCTCGCCTTCCCGATGTTCGCCACCGTCGTCTGGCTGGTC
TGGGTGCTCGGCCAGCAAAGCGGCATCGACGGCGCGGCGGCTTTGCTCGCGCTGCTCGTCGCGCTCGGCATGGTCGTGTG
GGCCTTCACGCTCGCCGGCCGGGCCCGCATGGCGATGGCGCCGCTCTCGCTGGTCGTGTTCGCCGCCCTGGCCATGGCGG
CCGTGCCGAAGATCACCGAAATGGCCCCGCCTGCGATGGCCTTTGCAGCCCCCGGCACATCCGGCGCGGCAGGCACCGCT
CCCAACGCCGCGGCCTGGCAGGCATGGCGCCCGGGCCTCGCGGAAGAACTGCTCGCCCAGGGCCGCCCCGTGTTCGTGGA
CTACACCGCCGCCTGGTGCGTCACCTGCCAGTTCAACAAGAAGACCACCCTCTCCAGCGATGCCGTGCTGCGCGAGTTCG
CAGGCCGCAACGTGGCCCTGCTGCGCGCCGACTGGACGCGCCGCGACCCGGCCATCACCGCCGCGCTGGCGCAACTGGGG
CGCAGCGGCGTGCCGGTTTATGTGCTGCAGGCGCCGGGCCGGCGGCCGGTGGTGTTCTCGGAAATCCTGGGCGAGCGCGA
ATTGCGCACGGCGCTGGCGGCGCTCTGA

Upstream 100 bases:

>100_bases
ATGGCCCGGCGCGTGGTGCTCGGCTTCGCGGCCTGAGCGCCACCGCTGCACGCCGCCCTTCCCGGAACCAAAGCCGCCCG
CGCCGCTCCCACACCGCGCC

Downstream 100 bases:

>100_bases
CGCCGGCAGCGCCAGGGCCGGCTGCGCCGGGAGCGGCGCGGCGATCGCGCCGCCGCGCTACGGGGCTGCCGCCTCGACGG
CATGCGCGCCGCACGGCGCC

Product: cytochrome c biogenesis protein transmembrane subunit

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MSVRLLQRLLPSFALLAACALGAPASAQLLSEPAAGISGGTPAGSSTVTTPHVRAELVAHAPDGVGPGKPLWLGLSITHQ
PEWHTYWKNPGDSGLPTQIEWRQLPPGIDAGEIAWPVPRKIPIGTLANYGYEGTVLLPVPMTVSGAFSPGPLARNATFTL
HASWLVCRKECIPEEGTFTLQVPIASTTAMQAQDFEAARQAHPQPLSLPAAAAAGGTRSHARVDRGMLVLTVAGLPEAVR
GKPMDFFPETPGIIETADDGTQDWQGDVWTARMPLSAQRSEGPMSLPVVLAQGGRGWRAELPVEGGWPRPASLATVSPAL
EAALRANAQQAAQALPAAATPAPAGALAAALLGALLGGLVLNLMPCVFPVLAIKVAGFARHGQDRRAHRLGGIAYTAGVV
LSFLALGGAMLALRAAGEAVGWGFQLQSPAVVAVLAALFTLIGLNLSGMFEFGRMLPSSLAGLQARHPAADAFLTGVLAV
AVASPCTAPFMGASVGLTATLPAAQALAVFAALGVGLALPYLAASWVPAVARALPRPGAWMDTLRRFLAFPMFATVVWLV
WVLGQQSGIDGAAALLALLVALGMVVWAFTLAGRARMAMAPLSLVVFAALAMAAVPKITEMAPPAMAFAAPGTSGAAGTA
PNAAAWQAWRPGLAEELLAQGRPVFVDYTAAWCVTCQFNKKTTLSSDAVLREFAGRNVALLRADWTRRDPAITAALAQLG
RSGVPVYVLQAPGRRPVVFSEILGERELRTALAAL

Sequences:

>Translated_755_residues
MSVRLLQRLLPSFALLAACALGAPASAQLLSEPAAGISGGTPAGSSTVTTPHVRAELVAHAPDGVGPGKPLWLGLSITHQ
PEWHTYWKNPGDSGLPTQIEWRQLPPGIDAGEIAWPVPRKIPIGTLANYGYEGTVLLPVPMTVSGAFSPGPLARNATFTL
HASWLVCRKECIPEEGTFTLQVPIASTTAMQAQDFEAARQAHPQPLSLPAAAAAGGTRSHARVDRGMLVLTVAGLPEAVR
GKPMDFFPETPGIIETADDGTQDWQGDVWTARMPLSAQRSEGPMSLPVVLAQGGRGWRAELPVEGGWPRPASLATVSPAL
EAALRANAQQAAQALPAAATPAPAGALAAALLGALLGGLVLNLMPCVFPVLAIKVAGFARHGQDRRAHRLGGIAYTAGVV
LSFLALGGAMLALRAAGEAVGWGFQLQSPAVVAVLAALFTLIGLNLSGMFEFGRMLPSSLAGLQARHPAADAFLTGVLAV
AVASPCTAPFMGASVGLTATLPAAQALAVFAALGVGLALPYLAASWVPAVARALPRPGAWMDTLRRFLAFPMFATVVWLV
WVLGQQSGIDGAAALLALLVALGMVVWAFTLAGRARMAMAPLSLVVFAALAMAAVPKITEMAPPAMAFAAPGTSGAAGTA
PNAAAWQAWRPGLAEELLAQGRPVFVDYTAAWCVTCQFNKKTTLSSDAVLREFAGRNVALLRADWTRRDPAITAALAQLG
RSGVPVYVLQAPGRRPVVFSEILGERELRTALAAL
>Mature_754_residues
SVRLLQRLLPSFALLAACALGAPASAQLLSEPAAGISGGTPAGSSTVTTPHVRAELVAHAPDGVGPGKPLWLGLSITHQP
EWHTYWKNPGDSGLPTQIEWRQLPPGIDAGEIAWPVPRKIPIGTLANYGYEGTVLLPVPMTVSGAFSPGPLARNATFTLH
ASWLVCRKECIPEEGTFTLQVPIASTTAMQAQDFEAARQAHPQPLSLPAAAAAGGTRSHARVDRGMLVLTVAGLPEAVRG
KPMDFFPETPGIIETADDGTQDWQGDVWTARMPLSAQRSEGPMSLPVVLAQGGRGWRAELPVEGGWPRPASLATVSPALE
AALRANAQQAAQALPAAATPAPAGALAAALLGALLGGLVLNLMPCVFPVLAIKVAGFARHGQDRRAHRLGGIAYTAGVVL
SFLALGGAMLALRAAGEAVGWGFQLQSPAVVAVLAALFTLIGLNLSGMFEFGRMLPSSLAGLQARHPAADAFLTGVLAVA
VASPCTAPFMGASVGLTATLPAAQALAVFAALGVGLALPYLAASWVPAVARALPRPGAWMDTLRRFLAFPMFATVVWLVW
VLGQQSGIDGAAALLALLVALGMVVWAFTLAGRARMAMAPLSLVVFAALAMAAVPKITEMAPPAMAFAAPGTSGAAGTAP
NAAAWQAWRPGLAEELLAQGRPVFVDYTAAWCVTCQFNKKTTLSSDAVLREFAGRNVALLRADWTRRDPAITAALAQLGR
SGVPVYVLQAPGRRPVVFSEILGERELRTALAAL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=490, Percent_Identity=27.7551020408163, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 78221; Mature: 78090

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRLLQRLLPSFALLAACALGAPASAQLLSEPAAGISGGTPAGSSTVTTPHVRAELVAH
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEE
APDGVGPGKPLWLGLSITHQPEWHTYWKNPGDSGLPTQIEWRQLPPGIDAGEIAWPVPRK
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEHCCCCCCCCCCCCCCCCCCC
IPIGTLANYGYEGTVLLPVPMTVSGAFSPGPLARNATFTLHASWLVCRKECIPEEGTFTL
CCCHHHHCCCCCCEEEEECCCEECCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCEEE
QVPIASTTAMQAQDFEAARQAHPQPLSLPAAAAAGGTRSHARVDRGMLVLTVAGLPEAVR
EEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHCCCEEEEEECCCCHHHC
GKPMDFFPETPGIIETADDGTQDWQGDVWTARMPLSAQRSEGPMSLPVVLAQGGRGWRAE
CCCCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEE
LPVEGGWPRPASLATVSPALEAALRANAQQAAQALPAAATPAPAGALAAALLGALLGGLV
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LNLMPCVFPVLAIKVAGFARHGQDRRAHRLGGIAYTAGVVLSFLALGGAMLALRAAGEAV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
GWGFQLQSPAVVAVLAALFTLIGLNLSGMFEFGRMLPSSLAGLQARHPAADAFLTGVLAV
CCCEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AVASPCTAPFMGASVGLTATLPAAQALAVFAALGVGLALPYLAASWVPAVARALPRPGAW
HHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
MDTLRRFLAFPMFATVVWLVWVLGQQSGIDGAAALLALLVALGMVVWAFTLAGRARMAMA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
PLSLVVFAALAMAAVPKITEMAPPAMAFAAPGTSGAAGTAPNAAAWQAWRPGLAEELLAQ
HHHHHHHHHHHHHHCCHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHCCCHHHHHHHC
GRPVFVDYTAAWCVTCQFNKKTTLSSDAVLREFAGRNVALLRADWTRRDPAITAALAQLG
CCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHC
RSGVPVYVLQAPGRRPVVFSEILGERELRTALAAL
CCCCCEEEEECCCCCCCHHHHHHCHHHHHHHHHCC
>Mature Secondary Structure 
SVRLLQRLLPSFALLAACALGAPASAQLLSEPAAGISGGTPAGSSTVTTPHVRAELVAH
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEE
APDGVGPGKPLWLGLSITHQPEWHTYWKNPGDSGLPTQIEWRQLPPGIDAGEIAWPVPRK
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEHCCCCCCCCCCCCCCCCCCC
IPIGTLANYGYEGTVLLPVPMTVSGAFSPGPLARNATFTLHASWLVCRKECIPEEGTFTL
CCCHHHHCCCCCCEEEEECCCEECCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCEEE
QVPIASTTAMQAQDFEAARQAHPQPLSLPAAAAAGGTRSHARVDRGMLVLTVAGLPEAVR
EEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHCCCEEEEEECCCCHHHC
GKPMDFFPETPGIIETADDGTQDWQGDVWTARMPLSAQRSEGPMSLPVVLAQGGRGWRAE
CCCCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEE
LPVEGGWPRPASLATVSPALEAALRANAQQAAQALPAAATPAPAGALAAALLGALLGGLV
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LNLMPCVFPVLAIKVAGFARHGQDRRAHRLGGIAYTAGVVLSFLALGGAMLALRAAGEAV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
GWGFQLQSPAVVAVLAALFTLIGLNLSGMFEFGRMLPSSLAGLQARHPAADAFLTGVLAV
CCCEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AVASPCTAPFMGASVGLTATLPAAQALAVFAALGVGLALPYLAASWVPAVARALPRPGAW
HHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
MDTLRRFLAFPMFATVVWLVWVLGQQSGIDGAAALLALLVALGMVVWAFTLAGRARMAMA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
PLSLVVFAALAMAAVPKITEMAPPAMAFAAPGTSGAAGTAPNAAAWQAWRPGLAEELLAQ
HHHHHHHHHHHHHHCCHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHCCCHHHHHHHC
GRPVFVDYTAAWCVTCQFNKKTTLSSDAVLREFAGRNVALLRADWTRRDPAITAALAQLG
CCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHC
RSGVPVYVLQAPGRRPVVFSEILGERELRTALAAL
CCCCCEEEEECCCCCCCHHHHHHCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA