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The map label for this gene is yisV [H]

Identifier: 120613070

GI number: 120613070

Start: 4928621

End: 4930081

Strand: Reverse

Name: yisV [H]

Synonym: Aave_4434

Alternate gene names: 120613070

Gene position: 4930081-4928621 (Counterclockwise)

Preceding gene: 120613078

Following gene: 120613063

Centisome position: 92.1

GC content: 73.44

Gene sequence:

>1461_bases
ATGCTGACCCGCACGCCCGACCGCACCCTGACCGAGCAGCTCGCCGAGCGATTCGCGGAACGCATCCGCAGCCGGCTGCT
GCCCGTCGGCGCGCGCCTGCCGTCGGTGCGCGAATGCGCGCGGCAGCAGGGCGTGAGCACCCACACCGTGGTCGCCGCCT
ACGACCAGTTGCTGGCGCAGGGCCTCGTGGAGGCGCGGCGCCAGCGCGGATTCTTCGTGCGCGACGCGGTGCAGCGGCCT
CCGGCCCCGGTGCCGGGCGCCCCTGTCGGCGCACCGCCTGGCGGGCCGGCCGCGGGGGCCTCGATCCTCGGCGCCGCCGC
GCTGCCGATGTCGGGCTCGCACATCAATGCCACCACCCTGATCCGCGGCATGTTCCACCAGGCCTCGTCCAAGCCCCAGC
CCGGCGCCGGCGTGTTCCCGCCGGACTGGCTCGAAGACGCGCGCTTCATGTCCGCCGCCGTACGCCGAGTCACCGCGGGG
CGTGCGCTGCAGGACGGCTCCCTGGTCTATGGCGAGCCCCGCGGCGATGCCGGGCTGCGCGCGGCGCTCGCACGGCGGCT
GGCCGACCTCAGCGTGCCGGCGGAGCCCGCGCAGATCATCACCACCGTCGGCGCCACGCATGCGCTGGACATCGTGAGCC
GCACCCTGCTGAAGGCCGGCGATCCGGTCATGGTGGAGGAGCCCGGCTGGTCGGTGGAGTTCGCGCGGCTCGATGCGCTG
GGCATGCGCGTGCTGCCCGTGCCGCGCGGCCCCGAGGGACCGGACCTGGACGTGATGGCGCGCTACTGCGAGGCCCATGC
ACCCAAGCTGTTCGTGAGCGTGAGCGTGCTGCACAACCCCACCGGCTACAGCCTGTCGCCGGGCCACGCGCACCGCATCC
TGCAGCTGTCCCACCGGCACGGCTTCCACATCGTCGAGGACGACACCTACGGACACATCGCCCCCGACCACGCCACGCGG
CTGTCGGCCCTGGACGGGCTGCGCCGCACCATCTACGTGAACGGCTTCGCCAAGATCCTCGCGCCCAACTGGCGGGTGGG
CTACCTCGCCGCGCCCGAGGGCCTGGTGGAGCGGCTGCTGGACACCAAGCTGCTGTCCACCCTCACCACGCCTTCCATCC
TCGAGAAAGCCCTGGCCCAGTGCATCGAGCAGGGCCAGCTGCGCCGCCACGCCGAGCGCATGCGCCTGCGCCTGGCCCAG
GCGCGGGCCCGCAGCGTGCAGATCGCGCTGGAGGCCGGGCAGCGCTTCGCGGCCGAGCCCGCGGGCATGTTCGGCTGGGT
GGAGACGGGCGTGGACACCGACATGCTCGCCCAGCGCATGCTCGACGAGGGCTACCTCATCGCGCCCGGCGCGCTGTTCC
ATGCCACCCGCCGGCCCTGCACGCTCATGCGCATCAACTTCACGACCACGCAGGACCCGGGGTTCTGGAAGGTGTTCCAG
CGCGCGGCACGGGGCCTCTGA

Upstream 100 bases:

>100_bases
CAGACAGCTGCACAAGTGCATGAACTGTGCCGGTGCGTAGAGCAACACAGTTCCACTCCGCCATCCCACACCGCCGCTCG
CATTCCCCCGAAAGGCTTCC

Downstream 100 bases:

>100_bases
CCGGGTTTCAGGACCGCATCGGCATGACCAGGATCTCGCAGACCACCCGGGGGGCATCTTCGCGGCGCGTTGAGCCCGGG
GCCAGGTCGCCATGGAAACC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MLTRTPDRTLTEQLAERFAERIRSRLLPVGARLPSVRECARQQGVSTHTVVAAYDQLLAQGLVEARRQRGFFVRDAVQRP
PAPVPGAPVGAPPGGPAAGASILGAAALPMSGSHINATTLIRGMFHQASSKPQPGAGVFPPDWLEDARFMSAAVRRVTAG
RALQDGSLVYGEPRGDAGLRAALARRLADLSVPAEPAQIITTVGATHALDIVSRTLLKAGDPVMVEEPGWSVEFARLDAL
GMRVLPVPRGPEGPDLDVMARYCEAHAPKLFVSVSVLHNPTGYSLSPGHAHRILQLSHRHGFHIVEDDTYGHIAPDHATR
LSALDGLRRTIYVNGFAKILAPNWRVGYLAAPEGLVERLLDTKLLSTLTTPSILEKALAQCIEQGQLRRHAERMRLRLAQ
ARARSVQIALEAGQRFAAEPAGMFGWVETGVDTDMLAQRMLDEGYLIAPGALFHATRRPCTLMRINFTTTQDPGFWKVFQ
RAARGL

Sequences:

>Translated_486_residues
MLTRTPDRTLTEQLAERFAERIRSRLLPVGARLPSVRECARQQGVSTHTVVAAYDQLLAQGLVEARRQRGFFVRDAVQRP
PAPVPGAPVGAPPGGPAAGASILGAAALPMSGSHINATTLIRGMFHQASSKPQPGAGVFPPDWLEDARFMSAAVRRVTAG
RALQDGSLVYGEPRGDAGLRAALARRLADLSVPAEPAQIITTVGATHALDIVSRTLLKAGDPVMVEEPGWSVEFARLDAL
GMRVLPVPRGPEGPDLDVMARYCEAHAPKLFVSVSVLHNPTGYSLSPGHAHRILQLSHRHGFHIVEDDTYGHIAPDHATR
LSALDGLRRTIYVNGFAKILAPNWRVGYLAAPEGLVERLLDTKLLSTLTTPSILEKALAQCIEQGQLRRHAERMRLRLAQ
ARARSVQIALEAGQRFAAEPAGMFGWVETGVDTDMLAQRMLDEGYLIAPGALFHATRRPCTLMRINFTTTQDPGFWKVFQ
RAARGL
>Mature_486_residues
MLTRTPDRTLTEQLAERFAERIRSRLLPVGARLPSVRECARQQGVSTHTVVAAYDQLLAQGLVEARRQRGFFVRDAVQRP
PAPVPGAPVGAPPGGPAAGASILGAAALPMSGSHINATTLIRGMFHQASSKPQPGAGVFPPDWLEDARFMSAAVRRVTAG
RALQDGSLVYGEPRGDAGLRAALARRLADLSVPAEPAQIITTVGATHALDIVSRTLLKAGDPVMVEEPGWSVEFARLDAL
GMRVLPVPRGPEGPDLDVMARYCEAHAPKLFVSVSVLHNPTGYSLSPGHAHRILQLSHRHGFHIVEDDTYGHIAPDHATR
LSALDGLRRTIYVNGFAKILAPNWRVGYLAAPEGLVERLLDTKLLSTLTTPSILEKALAQCIEQGQLRRHAERMRLRLAQ
ARARSVQIALEAGQRFAAEPAGMFGWVETGVDTDMLAQRMLDEGYLIAPGALFHATRRPCTLMRINFTTTQDPGFWKVFQ
RAARGL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=374, Percent_Identity=24.5989304812834, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI33469970, Length=374, Percent_Identity=24.5989304812834, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1787710, Length=467, Percent_Identity=28.051391862955, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1790797, Length=471, Percent_Identity=26.963906581741, Blast_Score=135, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6321929, Length=294, Percent_Identity=24.1496598639456, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321236, Length=318, Percent_Identity=23.5849056603774, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52702; Mature: 52702

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRTPDRTLTEQLAERFAERIRSRLLPVGARLPSVRECARQQGVSTHTVVAAYDQLLAQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
GLVEARRQRGFFVRDAVQRPPAPVPGAPVGAPPGGPAAGASILGAAALPMSGSHINATTL
HHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHH
IRGMFHQASSKPQPGAGVFPPDWLEDARFMSAAVRRVTAGRALQDGSLVYGEPRGDAGLR
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHH
AALARRLADLSVPAEPAQIITTVGATHALDIVSRTLLKAGDPVMVEEPGWSVEFARLDAL
HHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHC
GMRVLPVPRGPEGPDLDVMARYCEAHAPKLFVSVSVLHNPTGYSLSPGHAHRILQLSHRH
CCEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCC
GFHIVEDDTYGHIAPDHATRLSALDGLRRTIYVNGFAKILAPNWRVGYLAAPEGLVERLL
CCEEEECCCCCCCCCCHHHHHHHHHHHHHEEEECCHHHHHCCCCCEEEEECCHHHHHHHH
DTKLLSTLTTPSILEKALAQCIEQGQLRRHAERMRLRLAQARARSVQIALEAGQRFAAEP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCHHHCCC
AGMFGWVETGVDTDMLAQRMLDEGYLIAPGALFHATRRPCTLMRINFTTTQDPGFWKVFQ
CCCHHHHHCCCCHHHHHHHHHCCCEEECCHHHHHHCCCCEEEEEEEEECCCCCCHHHHHH
RAARGL
HHHCCC
>Mature Secondary Structure
MLTRTPDRTLTEQLAERFAERIRSRLLPVGARLPSVRECARQQGVSTHTVVAAYDQLLAQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
GLVEARRQRGFFVRDAVQRPPAPVPGAPVGAPPGGPAAGASILGAAALPMSGSHINATTL
HHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHH
IRGMFHQASSKPQPGAGVFPPDWLEDARFMSAAVRRVTAGRALQDGSLVYGEPRGDAGLR
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHH
AALARRLADLSVPAEPAQIITTVGATHALDIVSRTLLKAGDPVMVEEPGWSVEFARLDAL
HHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHC
GMRVLPVPRGPEGPDLDVMARYCEAHAPKLFVSVSVLHNPTGYSLSPGHAHRILQLSHRH
CCEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCC
GFHIVEDDTYGHIAPDHATRLSALDGLRRTIYVNGFAKILAPNWRVGYLAAPEGLVERLL
CCEEEECCCCCCCCCCHHHHHHHHHHHHHEEEECCHHHHHCCCCCEEEEECCHHHHHHHH
DTKLLSTLTTPSILEKALAQCIEQGQLRRHAERMRLRLAQARARSVQIALEAGQRFAAEP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCHHHCCC
AGMFGWVETGVDTDMLAQRMLDEGYLIAPGALFHATRRPCTLMRINFTTTQDPGFWKVFQ
CCCHHHHHCCCCHHHHHHHHHCCCEEECCHHHHHHCCCCEEEEEEEEECCCCCCHHHHHH
RAARGL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]