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The map label for this gene is livK [C]

Identifier: 120612978

GI number: 120612978

Start: 4823142

End: 4824263

Strand: Direct

Name: livK [C]

Synonym: Aave_4342

Alternate gene names: 120612978

Gene position: 4823142-4824263 (Clockwise)

Preceding gene: 120612976

Following gene: 120612992

Centisome position: 90.11

GC content: 68.72

Gene sequence:

>1122_bases
ATGGCCCATTCCTGGCAGACCACCGGCGCCGCCCTGGCCCTCGCGGCCGCTTCCCTGTTCTCTCCGGCCGCCTGGAGCCA
GTTGCAGGTGGGACAGACGGCCGGCTTCACCGGGCCCGTGTCCTCGGGCGTGCAGGAAACCACCGAGGGCGCGAAGCTCT
ACCTGGATGCGGTGAACGCGCGGGGCGGCGTGAATGGGCAGAAGATCGAGCTCATTTCGCTCGACGACAAGTTCGACCCC
GCCCTGGCGCAGGCCAACGCGCGCAAGCTCATCGAGGAGCAGAACGTGCTCGCGATGTTCCTCACCCGCGGCACGCCCCA
CACGGAAGCCATCATCCCCCTGCTCGACAAATTCGACGTCCCCCTCGTGGCTCCCTCCACGGGTGCGATGGTGCTGCACC
GCCCCGTGCGCCGACACGTATTCAACGTGCGAGCCCCCTACCAGCGCGAAGCCGAGAAGGCCATCACCCACCTGGCGTCG
ATGGGCATTTCCCGGATCGCGGTGGTCCTCACCGACGACAGCTTCGGCTCCGACGGGCTGGCGGGCGCGCTCAAGGGCTT
CGAGGCCGCGAAGCTCAAGCCCGTGCTGGAGGAGCGCTTCGACCGGGCCAAGCCCGATTTCTCCGCCATCGCGCCCAAGC
TGGCGCAGACGCAGGCCCAGGCCGTGCTCATGATCGCATCGGGGACCGCGGCGGTCGAAGGCTATGCGGCCTTCCGGGCG
GCCGGCTCGGGTGCCCAGCTCGTCACCCTGTCCAACAACGCATCGTCCGGATTCGCCAGGAGCCTGGGCGCGAATGCGCG
CGGCGTCATCGTCACGCAGGTGTTCCCGAACGAACGGGCCACGAACTATCCGCTCGTGCGCGAGGCGCACGACCTGGCGA
AAGCGCACGGCAAGGAAGTGAGCCCCGCCATGCTCGAAGGCATAGCGGCGGCCAAGGTGCTGGTGGAGGGACTGCGCCGC
GCGGGCGCCAAGCCCACGCGCGAACGCCTGCAGGCGGCACTGGAGGGCATCCAGAAATTCGACATCGGCGGCCTGGAGGT
GAACTTCAGCCCCGAGGACCACACCGGCCTGGATTTCGCCGACCTGTCCATCATCGGCACCGACGGCAAGTTCCGCCGCT
GA

Upstream 100 bases:

>100_bases
CTTCCGCGGACGTTCTGCACCGCAGCAACGGCGTACCGCCGCCGGCGCCGGCCCCGCGCCCATCGGACCACCCCACGCCT
TTCCTGGAGATTCCACCATC

Downstream 100 bases:

>100_bases
GCGGCGGCGGAAGTCCGGGCGGGCCCGCCCCGAGATGGCCACCCCGCACCCGGGGACCCGCATGGAAAAAGCCCGCTCCT
GCAGCGGGCTTTTTCGTTTC

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MAHSWQTTGAALALAAASLFSPAAWSQLQVGQTAGFTGPVSSGVQETTEGAKLYLDAVNARGGVNGQKIELISLDDKFDP
ALAQANARKLIEEQNVLAMFLTRGTPHTEAIIPLLDKFDVPLVAPSTGAMVLHRPVRRHVFNVRAPYQREAEKAITHLAS
MGISRIAVVLTDDSFGSDGLAGALKGFEAAKLKPVLEERFDRAKPDFSAIAPKLAQTQAQAVLMIASGTAAVEGYAAFRA
AGSGAQLVTLSNNASSGFARSLGANARGVIVTQVFPNERATNYPLVREAHDLAKAHGKEVSPAMLEGIAAAKVLVEGLRR
AGAKPTRERLQAALEGIQKFDIGGLEVNFSPEDHTGLDFADLSIIGTDGKFRR

Sequences:

>Translated_373_residues
MAHSWQTTGAALALAAASLFSPAAWSQLQVGQTAGFTGPVSSGVQETTEGAKLYLDAVNARGGVNGQKIELISLDDKFDP
ALAQANARKLIEEQNVLAMFLTRGTPHTEAIIPLLDKFDVPLVAPSTGAMVLHRPVRRHVFNVRAPYQREAEKAITHLAS
MGISRIAVVLTDDSFGSDGLAGALKGFEAAKLKPVLEERFDRAKPDFSAIAPKLAQTQAQAVLMIASGTAAVEGYAAFRA
AGSGAQLVTLSNNASSGFARSLGANARGVIVTQVFPNERATNYPLVREAHDLAKAHGKEVSPAMLEGIAAAKVLVEGLRR
AGAKPTRERLQAALEGIQKFDIGGLEVNFSPEDHTGLDFADLSIIGTDGKFRR
>Mature_372_residues
AHSWQTTGAALALAAASLFSPAAWSQLQVGQTAGFTGPVSSGVQETTEGAKLYLDAVNARGGVNGQKIELISLDDKFDPA
LAQANARKLIEEQNVLAMFLTRGTPHTEAIIPLLDKFDVPLVAPSTGAMVLHRPVRRHVFNVRAPYQREAEKAITHLASM
GISRIAVVLTDDSFGSDGLAGALKGFEAAKLKPVLEERFDRAKPDFSAIAPKLAQTQAQAVLMIASGTAAVEGYAAFRAA
GSGAQLVTLSNNASSGFARSLGANARGVIVTQVFPNERATNYPLVREAHDLAKAHGKEVSPAMLEGIAAAKVLVEGLRRA
GAKPTRERLQAALEGIQKFDIGGLEVNFSPEDHTGLDFADLSIIGTDGKFRR

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

None

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 39400; Mature: 39269

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSWQTTGAALALAAASLFSPAAWSQLQVGQTAGFTGPVSSGVQETTEGAKLYLDAVNA
CCCCCCCCHHHHHHHHHHHCCCCHHCCEECCCCCCCCCCHHCCHHHHCCCCEEEEEEECC
RGGVNGQKIELISLDDKFDPALAQANARKLIEEQNVLAMFLTRGTPHTEAIIPLLDKFDV
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCC
PLVAPSTGAMVLHRPVRRHVFNVRAPYQREAEKAITHLASMGISRIAVVLTDDSFGSDGL
CEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCH
AGALKGFEAAKLKPVLEERFDRAKPDFSAIAPKLAQTQAQAVLMIASGTAAVEGYAAFRA
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHC
AGSGAQLVTLSNNASSGFARSLGANARGVIVTQVFPNERATNYPLVREAHDLAKAHGKEV
CCCCCEEEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
SPAMLEGIAAAKVLVEGLRRAGAKPTRERLQAALEGIQKFDIGGLEVNFSPEDHTGLDFA
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEE
DLSIIGTDGKFRR
EEEEECCCCCCCC
>Mature Secondary Structure 
AHSWQTTGAALALAAASLFSPAAWSQLQVGQTAGFTGPVSSGVQETTEGAKLYLDAVNA
CCCCCCCHHHHHHHHHHHCCCCHHCCEECCCCCCCCCCHHCCHHHHCCCCEEEEEEECC
RGGVNGQKIELISLDDKFDPALAQANARKLIEEQNVLAMFLTRGTPHTEAIIPLLDKFDV
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCC
PLVAPSTGAMVLHRPVRRHVFNVRAPYQREAEKAITHLASMGISRIAVVLTDDSFGSDGL
CEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCH
AGALKGFEAAKLKPVLEERFDRAKPDFSAIAPKLAQTQAQAVLMIASGTAAVEGYAAFRA
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHC
AGSGAQLVTLSNNASSGFARSLGANARGVIVTQVFPNERATNYPLVREAHDLAKAHGKEV
CCCCCEEEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
SPAMLEGIAAAKVLVEGLRRAGAKPTRERLQAALEGIQKFDIGGLEVNFSPEDHTGLDFA
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEE
DLSIIGTDGKFRR
EEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]