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The map label for this gene is ybdL [H]

Identifier: 120611826

GI number: 120611826

Start: 3496197

End: 3497366

Strand: Direct

Name: ybdL [H]

Synonym: Aave_3167

Alternate gene names: 120611826

Gene position: 3496197-3497366 (Clockwise)

Preceding gene: 120611825

Following gene: 120611841

Centisome position: 65.32

GC content: 70.51

Gene sequence:

>1170_bases
ATGACCACCACCGCTGCCGCGCGCACGCCGGCCCTCCCCAGCAAGCTGCCCCAGGTGGGCACGACCATCTTTGCCGTGAT
GTCCGCCCTGGCGGCGGAGCACGGCGCCGTGAACCTGGGCCAGGGCTTTCCCGATTTCGACTGCGATCCGGCCCTGGTCG
ATGCGGTGGCCGGCGCCATGCGCGCGGGCCACAACCAGTACCCGCCGATGCCGGGCGTGCCGGCGCTGCGCCAGGCCGTG
GCGCGCAAGATCGAGGCGCTGCATGGCCGCGCCTATTCGCCGGACACCGAAATCACCGTGACGGCCGGCGCCACGCAGGG
CATCCTGACGGCGATCCTGGCCGTGGTGCAGGCGGGCGACGAGGTGATCGTGCTCGATCCCTGCTACGACAGCTACGTGC
CCAACGTGGAGCTGGCGGGCGGCACGGCGGTGCGCGTGCCGCTCACGCCCGGCACCTTCCGCCCGGATTTCGGCCGCATC
GCCGCCGCGCTCACGCCGCGCACGCGCGCGATCATTGTCAACACGCCGCACAACCCCTCGGCCACCGTATGGACGGACGA
GGACATGCGGGCACTCGAAGCGCTGCTCGCGCCCACCGACGTGGTCGTGGTCAGCGACGAGGTCTACGAGCACATGGTGT
TCGACGGTGCGGAGCACCAGAGCGTCGCGCGCTTCCCCGGGCTGGCCGCGCGAGCGTTCATCGTGTCGAGCTTCGGCAAG
ACCTTCCACGTCACGGGCTGGAAGGTGGGCACGGTGGTCGCACCCGCGCCGCTCATGGCCGAGTTCCGCAAGGTGCACCA
GTTCAACGTGTTCACGGTGAACACGCCCGTGCAGCATGGCCTGGCGGCCTACCTGGCCGATCCGGCGCCCTACCGGCAGC
TGCCGGCCTTCTACCAGGCCAAGCGCGACCTGTTCCGCCAGGGGCTGGAAGGCTCGCGCCTGAAACTGCTGCCCAGCACC
GGCAGCTACTTCCAGTGCGTGGACATCTCGCAGGTGAGCGACCTGGGCGACGTGGAGTTCTGCCAGTGGCTCACGCGCGA
GATCGGCGTGGCCGGCATCCCGCTGTCGCCGTTCTACGGCGACGGGTTCGATCAGCGCGTGGTGCGCTTCTGCTTCGCCA
AGCGCGACGAGACGCTGCGCGAGGCGCTGCAGCGGCTGCGCCGGCTCTGA

Upstream 100 bases:

>100_bases
GCGGAACTGCTCAGCGACCGGCTGAACCGCGAACTCGTGGCCCGCGCGATGACCGGGCACGTGAACGACTACGAGCTTTG
ATTTCCTGCCTCCCACGCCC

Downstream 100 bases:

>100_bases
GCGGCTGCTCTCTTCCCTAGCCTTCCGCCATGCGCGCGAGGGCGCGGCACGGCAGGCTGGCCGGATCCTCGAAGGCCTGC
ACGGCATCGAAGTGGTCGGC

Product: putative aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTTTAAARTPALPSKLPQVGTTIFAVMSALAAEHGAVNLGQGFPDFDCDPALVDAVAGAMRAGHNQYPPMPGVPALRQAV
ARKIEALHGRAYSPDTEITVTAGATQGILTAILAVVQAGDEVIVLDPCYDSYVPNVELAGGTAVRVPLTPGTFRPDFGRI
AAALTPRTRAIIVNTPHNPSATVWTDEDMRALEALLAPTDVVVVSDEVYEHMVFDGAEHQSVARFPGLAARAFIVSSFGK
TFHVTGWKVGTVVAPAPLMAEFRKVHQFNVFTVNTPVQHGLAAYLADPAPYRQLPAFYQAKRDLFRQGLEGSRLKLLPST
GSYFQCVDISQVSDLGDVEFCQWLTREIGVAGIPLSPFYGDGFDQRVVRFCFAKRDETLREALQRLRRL

Sequences:

>Translated_389_residues
MTTTAAARTPALPSKLPQVGTTIFAVMSALAAEHGAVNLGQGFPDFDCDPALVDAVAGAMRAGHNQYPPMPGVPALRQAV
ARKIEALHGRAYSPDTEITVTAGATQGILTAILAVVQAGDEVIVLDPCYDSYVPNVELAGGTAVRVPLTPGTFRPDFGRI
AAALTPRTRAIIVNTPHNPSATVWTDEDMRALEALLAPTDVVVVSDEVYEHMVFDGAEHQSVARFPGLAARAFIVSSFGK
TFHVTGWKVGTVVAPAPLMAEFRKVHQFNVFTVNTPVQHGLAAYLADPAPYRQLPAFYQAKRDLFRQGLEGSRLKLLPST
GSYFQCVDISQVSDLGDVEFCQWLTREIGVAGIPLSPFYGDGFDQRVVRFCFAKRDETLREALQRLRRL
>Mature_388_residues
TTTAAARTPALPSKLPQVGTTIFAVMSALAAEHGAVNLGQGFPDFDCDPALVDAVAGAMRAGHNQYPPMPGVPALRQAVA
RKIEALHGRAYSPDTEITVTAGATQGILTAILAVVQAGDEVIVLDPCYDSYVPNVELAGGTAVRVPLTPGTFRPDFGRIA
AALTPRTRAIIVNTPHNPSATVWTDEDMRALEALLAPTDVVVVSDEVYEHMVFDGAEHQSVARFPGLAARAFIVSSFGKT
FHVTGWKVGTVVAPAPLMAEFRKVHQFNVFTVNTPVQHGLAAYLADPAPYRQLPAFYQAKRDLFRQGLEGSRLKLLPSTG
SYFQCVDISQVSDLGDVEFCQWLTREIGVAGIPLSPFYGDGFDQRVVRFCFAKRDETLREALQRLRRL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=36.2025316455696, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=36.2025316455696, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI56713254, Length=408, Percent_Identity=33.578431372549, Blast_Score=228, Evalue=8e-60,
Organism=Homo sapiens, GI56713256, Length=409, Percent_Identity=33.4963325183374, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=32.5699745547074, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI4507369, Length=215, Percent_Identity=24.6511627906977, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1786816, Length=384, Percent_Identity=54.9479166666667, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=26.010101010101, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788627, Length=280, Percent_Identity=26.7857142857143, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787710, Length=349, Percent_Identity=27.2206303724928, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=409, Percent_Identity=32.2738386308068, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71994472, Length=409, Percent_Identity=32.2738386308068, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17567369, Length=420, Percent_Identity=30.7142857142857, Blast_Score=190, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17567663, Length=364, Percent_Identity=25.8241758241758, Blast_Score=95, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=31.701030927835, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI28573069, Length=411, Percent_Identity=34.0632603406326, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI24646114, Length=411, Percent_Identity=34.0632603406326, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI28573067, Length=411, Percent_Identity=34.0632603406326, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI28573065, Length=411, Percent_Identity=34.0632603406326, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI18859735, Length=213, Percent_Identity=28.169014084507, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42032; Mature: 41901

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTAAARTPALPSKLPQVGTTIFAVMSALAAEHGAVNLGQGFPDFDCDPALVDAVAGAM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHH
RAGHNQYPPMPGVPALRQAVARKIEALHGRAYSPDTEITVTAGATQGILTAILAVVQAGD
HCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCC
EVIVLDPCYDSYVPNVELAGGTAVRVPLTPGTFRPDFGRIAAALTPRTRAIIVNTPHNPS
CEEEECCCCCCCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCC
ATVWTDEDMRALEALLAPTDVVVVSDEVYEHMVFDGAEHQSVARFPGLAARAFIVSSFGK
EEEEECHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCC
TFHVTGWKVGTVVAPAPLMAEFRKVHQFNVFTVNTPVQHGLAAYLADPAPYRQLPAFYQA
EEEECCEEECEEECCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHH
KRDLFRQGLEGSRLKLLPSTGSYFQCVDISQVSDLGDVEFCQWLTREIGVAGIPLSPFYG
HHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DGFDQRVVRFCFAKRDETLREALQRLRRL
CCHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TTTAAARTPALPSKLPQVGTTIFAVMSALAAEHGAVNLGQGFPDFDCDPALVDAVAGAM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHH
RAGHNQYPPMPGVPALRQAVARKIEALHGRAYSPDTEITVTAGATQGILTAILAVVQAGD
HCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCC
EVIVLDPCYDSYVPNVELAGGTAVRVPLTPGTFRPDFGRIAAALTPRTRAIIVNTPHNPS
CEEEECCCCCCCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCC
ATVWTDEDMRALEALLAPTDVVVVSDEVYEHMVFDGAEHQSVARFPGLAARAFIVSSFGK
EEEEECHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCC
TFHVTGWKVGTVVAPAPLMAEFRKVHQFNVFTVNTPVQHGLAAYLADPAPYRQLPAFYQA
EEEECCEEECEEECCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHH
KRDLFRQGLEGSRLKLLPSTGSYFQCVDISQVSDLGDVEFCQWLTREIGVAGIPLSPFYG
HHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DGFDQRVVRFCFAKRDETLREALQRLRRL
CCHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]