Click here to switch to the map view.

The map label for this gene is yueD [H]

Identifier: 120611811

GI number: 120611811

Start: 3479253

End: 3480065

Strand: Direct

Name: yueD [H]

Synonym: Aave_3151

Alternate gene names: 120611811

Gene position: 3479253-3480065 (Clockwise)

Preceding gene: 120611810

Following gene: 120611812

Centisome position: 65.0

GC content: 74.42

Gene sequence:

>813_bases
ATGCAGGACACCTCCGCCCCCACCTCTTCTTCACCCAGCTCCGCGGCCATGCCCGGAGCCCTGCCCCTGGTCGTGCTCAC
CGGCGCCTCGCGCGGCATGGGCCTGGCTATGGCCCGGCAACTGCTGCAGGGCGGGCATGCGCTCGTCACCCTCTCGCGCG
GCACGAGCAGCGAGCTGGAAGACGTCGCGCAGCGCACCGGCATGCCGCTGGCGCAATGGCCGCAGGACCTCGCCGACGGC
GCCCGGGCCGCCGCCCGGCTGCGCGCATGGCTGGAAGACCAGCCGTCCGGCCGATACGCCAGCGCCACGCTCATCAACAA
CGCGGGCGTGGTGCCCCGCATCGCACCGCTGGCCGACAGCGACCCGGCCGATCTCGCCAATGCGCTGCGCATCGGGCTGG
AGGCGCCCATGCAGCTCACCGCCGCATTCCTGGCCGCCACGCGCGGCTGGGGCGTGCCGCGCAAGGTGCTCAACATTTCC
TCCGGCCTCGGGCGGCGGCCGATGGCCTCGCAATCGGCCTACTGCGCGGCCAAGGCCGGCATGGACCATTTCACGCGCTG
CCTCGCGCTGGACGAGGCGCGGCAGCCCGGCGGCGCCCGGGTGTGCTCGCTGGCGCCCGGCGTGATCGACACGGACATGC
AGGTCCATTTGCGCGGCGCCGACCCCGGGGCGTTCCCCGATGTGCAGAACTTCGCCCAGCTGAAGGCGACCGGCATGCTC
GCCTCGCCCGGCGAGGCCGCGGCGCGCGTGCTGGCCTGGCTCGCGCGGCCCGATTTCGGCGACGCGCCCGTGGCCGACGT
GCGCGAGGCCTGA

Upstream 100 bases:

>100_bases
CGCAGCACATCGCCTTCGCCCACCCGCGCACCGGAACGCCGCTCGCCTTCGAGCTGCCAGCGCCGTTCTGAGCACCGCGC
CGCAGTACCATCGCGGCACC

Downstream 100 bases:

>100_bases
GCGCCCCCCGCGCATGAGAAACTAGGCCGCGCCGCCCGCCCGCGGGACAGGCGTTCCTTTCCCGGAGACAAACACCCATG
ATCCGTTCGCTGATTTCGTT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQDTSAPTSSSPSSAAMPGALPLVVLTGASRGMGLAMARQLLQGGHALVTLSRGTSSELEDVAQRTGMPLAQWPQDLADG
ARAAARLRAWLEDQPSGRYASATLINNAGVVPRIAPLADSDPADLANALRIGLEAPMQLTAAFLAATRGWGVPRKVLNIS
SGLGRRPMASQSAYCAAKAGMDHFTRCLALDEARQPGGARVCSLAPGVIDTDMQVHLRGADPGAFPDVQNFAQLKATGML
ASPGEAAARVLAWLARPDFGDAPVADVREA

Sequences:

>Translated_270_residues
MQDTSAPTSSSPSSAAMPGALPLVVLTGASRGMGLAMARQLLQGGHALVTLSRGTSSELEDVAQRTGMPLAQWPQDLADG
ARAAARLRAWLEDQPSGRYASATLINNAGVVPRIAPLADSDPADLANALRIGLEAPMQLTAAFLAATRGWGVPRKVLNIS
SGLGRRPMASQSAYCAAKAGMDHFTRCLALDEARQPGGARVCSLAPGVIDTDMQVHLRGADPGAFPDVQNFAQLKATGML
ASPGEAAARVLAWLARPDFGDAPVADVREA
>Mature_270_residues
MQDTSAPTSSSPSSAAMPGALPLVVLTGASRGMGLAMARQLLQGGHALVTLSRGTSSELEDVAQRTGMPLAQWPQDLADG
ARAAARLRAWLEDQPSGRYASATLINNAGVVPRIAPLADSDPADLANALRIGLEAPMQLTAAFLAATRGWGVPRKVLNIS
SGLGRRPMASQSAYCAAKAGMDHFTRCLALDEARQPGGARVCSLAPGVIDTDMQVHLRGADPGAFPDVQNFAQLKATGML
ASPGEAAARVLAWLARPDFGDAPVADVREA

Specific function: Reduces benzil stereospecifically to (S)-benzoin. Can also reduces 1-phenyl-1,2-propanedione, 1,4-naphthoquinone, 1-(4- methyl-phenyl)-2-phenyl-ethane-1,2-dione, 1-(4-fluoro-phenyl)-2- phenyl-ethane-1,2-dione, methyl benzoylformate, p- nitrobenzaldehyde i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4507185, Length=267, Percent_Identity=32.5842696629214, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=205, Percent_Identity=31.219512195122, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=29.0196078431373, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=247, Percent_Identity=25.9109311740891, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21357041, Length=242, Percent_Identity=30.1652892561983, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640597, Length=260, Percent_Identity=25.7692307692308, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI23397609, Length=197, Percent_Identity=31.4720812182741, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=28.9156626506024, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=29.9180327868852, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27928; Mature: 27928

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDTSAPTSSSPSSAAMPGALPLVVLTGASRGMGLAMARQLLQGGHALVTLSRGTSSELE
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHH
DVAQRTGMPLAQWPQDLADGARAAARLRAWLEDQPSGRYASATLINNAGVVPRIAPLADS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCC
DPADLANALRIGLEAPMQLTAAFLAATRGWGVPRKVLNISSGLGRRPMASQSAYCAAKAG
CHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHC
MDHFTRCLALDEARQPGGARVCSLAPGVIDTDMQVHLRGADPGAFPDVQNFAQLKATGML
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCC
ASPGEAAARVLAWLARPDFGDAPVADVREA
CCCHHHHHHHHHHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure
MQDTSAPTSSSPSSAAMPGALPLVVLTGASRGMGLAMARQLLQGGHALVTLSRGTSSELE
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHH
DVAQRTGMPLAQWPQDLADGARAAARLRAWLEDQPSGRYASATLINNAGVVPRIAPLADS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCC
DPADLANALRIGLEAPMQLTAAFLAATRGWGVPRKVLNISSGLGRRPMASQSAYCAAKAG
CHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHC
MDHFTRCLALDEARQPGGARVCSLAPGVIDTDMQVHLRGADPGAFPDVQNFAQLKATGML
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCC
ASPGEAAARVLAWLARPDFGDAPVADVREA
CCCHHHHHHHHHHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11745140; 11796169 [H]