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The map label for this gene is yuxL [H]

Identifier: 120611748

GI number: 120611748

Start: 3404897

End: 3406882

Strand: Reverse

Name: yuxL [H]

Synonym: Aave_3088

Alternate gene names: 120611748

Gene position: 3406882-3404897 (Counterclockwise)

Preceding gene: 120611750

Following gene: 120611745

Centisome position: 63.65

GC content: 71.85

Gene sequence:

>1986_bases
GTGAGCGCCGCGCCGTGGACGGCGGAGGATATCGCGGGCCACCACTCGATCGCCGGGGTGCAGGGCTCGCCCACCGAGGA
ACTGCTGGTCTGTACCGTGGAGCGCGTCAATCGCGCCGCCGACCGCTCCGAGAGTTCCCTGTGGTGCGTGCCGCTGGAAG
GAGGGGCGCCGTGGCCCCTGACGGGCGGCACCTCCACGGACAACAATCCCCGCTGGTCCCCCGATGGCAAGCAGGTGGCC
TTCATCTCGATGCGTACCGGCAGCAGCCAGGTGTTCGTGATCGCGCGCCATGGCGGCGAAGCCCGCCAGGTCGGTGCCCT
GGACGGTACCGCGCTCTCGGCCGAGTGGTCGCCCGACGGCTGCAGCCTCGCGGTGCTGTGTACCGTGGCGGTCGATCCCG
AACTGCGGGGCCGCCGCCCGGGCCCGGACGCGCCACCCCCGCGCACGGGTGGCCCGCGGATCGTCTGGCGCCTGCCCTAC
AAGTCGGACGGGCTGGGTTATGTGCTGGGCCAGGAGACCCACCTGTTCGTGCTGCGCGTCTCCGACGGCCAGTGCAGGCG
CCTGACCGATGGCGCATTCAACGTGCGCGCCGCTGCGTGGTCGCCCGACGGCCGCACGATCGCGATGGTCCGCACGCGCG
ACAGCGATACCGAAGGGCACCGCACCGACCTCTGGACGCTGCGGGCCGACGGCGGTGACGCGCGCCAGCTGACGGACGGC
CTGGCCCAGGTGCTGTCGCCCGTGTGGTCGCCGGACGGGCGCACCATCGTCGTCTCCGGGTCGCGGGACGAAGGCGACGC
CCTGGTGCGGCTGTGGCAGTGCGATGCCGAAGGCGGCCGTGTCGAGCCGCTGGGTGATCCTTCGATCGAGATCGGGACCG
AAACCTCCAGCGTTCGTTTCGTGGACGGTGACCCGGGGCGGGTGCTGGCCCTTTTGATGCGTCGGGGAGTGCATGCAGTC
GCTTCGATCGCGGTGCCGGGCGGCGAGGTCCGCGTGATCGTGGAGGACGACCGCCAGCGGCTGGCGCTGGCCCATACGCG
CTCGCGCCTGGCGTTCGTCGCCCACACGCCGTCGGAGCCCATGGAAATCCAGGCGTGCGGCCGGGACGGAAGCGGCGCAC
ACACGGTCACTGCGTTCAACGCGGCATGGTGCAGGGGCCACCCTGGCGCGACCGTCGAGCGGCGATGCTTCACCGTTCCC
GACGGCGAAGGCGGAACGCATGCCATCGATGGCTGGCTGCTGCGCCCGGCCGGCGCCGCGGGCCCCGGGCCGCTGCTGGT
CGATCTGCACGGCGGTCCGGCGTCCCATGCACTTTTCGACTACCAGGCCACCGCGTACTGGCCGGTACTGTGGTCCCGCG
GCTGGTCGATCCTGGCGCTCAACCCCTCGGGCTCGGCCGGATACGGCCGGGATTTCGCCGAACGCCTGCGAGGCTGCTGG
GGCGAGCGGGACCTGCCCGAGGTGCTCGCGGCGCTGGAGACGCTGCAGCGCGAAGGCCTTGCGGATGAAAGAGTTGCCGT
TTGCGGAAAATCTTACGGCGGCTTCCTGAGCGCCTGGGCCATCGGCCACACGGACCGCTTCCGCGCCGCGGTCGTGATGG
CGCCGGTCGCCGACGCCCGCGGGCACTATGGCACCTCCGACAGCGGCTACTACGCGGACCCCTTCGATTTCGGAGGCACG
CCCTGGAGCGTCCCGCAGGCCTACCTGCAGCGCTCCACGCTGCCCGGCGCGGCTCGGGCCCGCACGCCCACGCTCATCCT
GCAGGGAGAAGACGATGAGCGCTGCCCGGTCGGGCAGAGCGAGGCGCTGTTCTGCGCGCTCAAGCGCGGGGCGAATCCAC
CGTGCGAACTGGTGATCTATCCGGGCGAAGGTCATGCGTTCACCTCGGCGGGGACGCCTTCGGTGCGCGAGGATGCGGTG
CGGCGTATCGTGGAGTGGCTGGCGCGCTGGACGGAGCCTCCGGTGCGGCCGCAGCGCGCGCCCTGA

Upstream 100 bases:

>100_bases
TGCCCATGATCCACCATCACACTATCGTTTCGCTGCCACGCCGGGCCGCCATGGCCACCGAACCGCCGTCAGGCTGCCGC
AGGTCGCAGGAGGGAGGGGC

Downstream 100 bases:

>100_bases
CCCCCCCCCGTGGGGCCGGCACGCGCTGGACGGGTCAGCGGCGGGCCTGCGGGGTCCCGCGGTCCTGGTTCAGGCTGCCG
CCGGTGTTCTGCTCGCGCTC

Product: peptidase S9 prolyl oligopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MSAAPWTAEDIAGHHSIAGVQGSPTEELLVCTVERVNRAADRSESSLWCVPLEGGAPWPLTGGTSTDNNPRWSPDGKQVA
FISMRTGSSQVFVIARHGGEARQVGALDGTALSAEWSPDGCSLAVLCTVAVDPELRGRRPGPDAPPPRTGGPRIVWRLPY
KSDGLGYVLGQETHLFVLRVSDGQCRRLTDGAFNVRAAAWSPDGRTIAMVRTRDSDTEGHRTDLWTLRADGGDARQLTDG
LAQVLSPVWSPDGRTIVVSGSRDEGDALVRLWQCDAEGGRVEPLGDPSIEIGTETSSVRFVDGDPGRVLALLMRRGVHAV
ASIAVPGGEVRVIVEDDRQRLALAHTRSRLAFVAHTPSEPMEIQACGRDGSGAHTVTAFNAAWCRGHPGATVERRCFTVP
DGEGGTHAIDGWLLRPAGAAGPGPLLVDLHGGPASHALFDYQATAYWPVLWSRGWSILALNPSGSAGYGRDFAERLRGCW
GERDLPEVLAALETLQREGLADERVAVCGKSYGGFLSAWAIGHTDRFRAAVVMAPVADARGHYGTSDSGYYADPFDFGGT
PWSVPQAYLQRSTLPGAARARTPTLILQGEDDERCPVGQSEALFCALKRGANPPCELVIYPGEGHAFTSAGTPSVREDAV
RRIVEWLARWTEPPVRPQRAP

Sequences:

>Translated_661_residues
MSAAPWTAEDIAGHHSIAGVQGSPTEELLVCTVERVNRAADRSESSLWCVPLEGGAPWPLTGGTSTDNNPRWSPDGKQVA
FISMRTGSSQVFVIARHGGEARQVGALDGTALSAEWSPDGCSLAVLCTVAVDPELRGRRPGPDAPPPRTGGPRIVWRLPY
KSDGLGYVLGQETHLFVLRVSDGQCRRLTDGAFNVRAAAWSPDGRTIAMVRTRDSDTEGHRTDLWTLRADGGDARQLTDG
LAQVLSPVWSPDGRTIVVSGSRDEGDALVRLWQCDAEGGRVEPLGDPSIEIGTETSSVRFVDGDPGRVLALLMRRGVHAV
ASIAVPGGEVRVIVEDDRQRLALAHTRSRLAFVAHTPSEPMEIQACGRDGSGAHTVTAFNAAWCRGHPGATVERRCFTVP
DGEGGTHAIDGWLLRPAGAAGPGPLLVDLHGGPASHALFDYQATAYWPVLWSRGWSILALNPSGSAGYGRDFAERLRGCW
GERDLPEVLAALETLQREGLADERVAVCGKSYGGFLSAWAIGHTDRFRAAVVMAPVADARGHYGTSDSGYYADPFDFGGT
PWSVPQAYLQRSTLPGAARARTPTLILQGEDDERCPVGQSEALFCALKRGANPPCELVIYPGEGHAFTSAGTPSVREDAV
RRIVEWLARWTEPPVRPQRAP
>Mature_660_residues
SAAPWTAEDIAGHHSIAGVQGSPTEELLVCTVERVNRAADRSESSLWCVPLEGGAPWPLTGGTSTDNNPRWSPDGKQVAF
ISMRTGSSQVFVIARHGGEARQVGALDGTALSAEWSPDGCSLAVLCTVAVDPELRGRRPGPDAPPPRTGGPRIVWRLPYK
SDGLGYVLGQETHLFVLRVSDGQCRRLTDGAFNVRAAAWSPDGRTIAMVRTRDSDTEGHRTDLWTLRADGGDARQLTDGL
AQVLSPVWSPDGRTIVVSGSRDEGDALVRLWQCDAEGGRVEPLGDPSIEIGTETSSVRFVDGDPGRVLALLMRRGVHAVA
SIAVPGGEVRVIVEDDRQRLALAHTRSRLAFVAHTPSEPMEIQACGRDGSGAHTVTAFNAAWCRGHPGATVERRCFTVPD
GEGGTHAIDGWLLRPAGAAGPGPLLVDLHGGPASHALFDYQATAYWPVLWSRGWSILALNPSGSAGYGRDFAERLRGCWG
ERDLPEVLAALETLQREGLADERVAVCGKSYGGFLSAWAIGHTDRFRAAVVMAPVADARGHYGTSDSGYYADPFDFGGTP
WSVPQAYLQRSTLPGAARARTPTLILQGEDDERCPVGQSEALFCALKRGANPPCELVIYPGEGHAFTSAGTPSVREDAVR
RIVEWLARWTEPPVRPQRAP

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=235, Percent_Identity=31.9148936170213, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25144537, Length=217, Percent_Identity=29.9539170506912, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25144540, Length=217, Percent_Identity=29.9539170506912, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25149159, Length=532, Percent_Identity=22.3684210526316, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 70760; Mature: 70629

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAPWTAEDIAGHHSIAGVQGSPTEELLVCTVERVNRAADRSESSLWCVPLEGGAPWPL
CCCCCCCHHHHCCCCEECCCCCCCCHHEEEEEHHHHHHHHCCCCCCEEEEECCCCCCCCC
TGGTSTDNNPRWSPDGKQVAFISMRTGSSQVFVIARHGGEARQVGALDGTALSAEWSPDG
CCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCEEECCCCCCEEEECCCCCC
CSLAVLCTVAVDPELRGRRPGPDAPPPRTGGPRIVWRLPYKSDGLGYVLGQETHLFVLRV
CEEEEEEEEEECCHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCEEEEEEEE
SDGQCRRLTDGAFNVRAAAWSPDGRTIAMVRTRDSDTEGHRTDLWTLRADGGDARQLTDG
CCCCCEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHH
LAQVLSPVWSPDGRTIVVSGSRDEGDALVRLWQCDAEGGRVEPLGDPSIEIGTETSSVRF
HHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCCEECCCCCCCEEECCCCCEEEE
VDGDPGRVLALLMRRGVHAVASIAVPGGEVRVIVEDDRQRLALAHTRSRLAFVAHTPSEP
EECCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCEEHHHHCCEEEEEEECCCCC
MEIQACGRDGSGAHTVTAFNAAWCRGHPGATVERRCFTVPDGEGGTHAIDGWLLRPAGAA
EEEEECCCCCCCCEEEEEECCCEECCCCCCCCCCEEEECCCCCCCCEEECCEEECCCCCC
GPGPLLVDLHGGPASHALFDYQATAYWPVLWSRGWSILALNPSGSAGYGRDFAERLRGCW
CCCCEEEEECCCCCCCEEEECCCCEEEEHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCC
GERDLPEVLAALETLQREGLADERVAVCGKSYGGFLSAWAIGHTDRFRAAVVMAPVADAR
CCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCCC
GHYGTSDSGYYADPFDFGGTPWSVPQAYLQRSTLPGAARARTPTLILQGEDDERCPVGQS
CCCCCCCCCEECCCCCCCCCCCCCHHHHHHHCCCCCCHHCCCCEEEEECCCCCCCCCCCC
EALFCALKRGANPPCELVIYPGEGHAFTSAGTPSVREDAVRRIVEWLARWTEPPVRPQRA
CCEEHEEHHCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
P
C
>Mature Secondary Structure 
SAAPWTAEDIAGHHSIAGVQGSPTEELLVCTVERVNRAADRSESSLWCVPLEGGAPWPL
CCCCCCHHHHCCCCEECCCCCCCCHHEEEEEHHHHHHHHCCCCCCEEEEECCCCCCCCC
TGGTSTDNNPRWSPDGKQVAFISMRTGSSQVFVIARHGGEARQVGALDGTALSAEWSPDG
CCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCEEECCCCCCEEEECCCCCC
CSLAVLCTVAVDPELRGRRPGPDAPPPRTGGPRIVWRLPYKSDGLGYVLGQETHLFVLRV
CEEEEEEEEEECCHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCEEEEEEEE
SDGQCRRLTDGAFNVRAAAWSPDGRTIAMVRTRDSDTEGHRTDLWTLRADGGDARQLTDG
CCCCCEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHH
LAQVLSPVWSPDGRTIVVSGSRDEGDALVRLWQCDAEGGRVEPLGDPSIEIGTETSSVRF
HHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCCEECCCCCCCEEECCCCCEEEE
VDGDPGRVLALLMRRGVHAVASIAVPGGEVRVIVEDDRQRLALAHTRSRLAFVAHTPSEP
EECCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCEEHHHHCCEEEEEEECCCCC
MEIQACGRDGSGAHTVTAFNAAWCRGHPGATVERRCFTVPDGEGGTHAIDGWLLRPAGAA
EEEEECCCCCCCCEEEEEECCCEECCCCCCCCCCEEEECCCCCCCCEEECCEEECCCCCC
GPGPLLVDLHGGPASHALFDYQATAYWPVLWSRGWSILALNPSGSAGYGRDFAERLRGCW
CCCCEEEEECCCCCCCEEEECCCCEEEEHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCC
GERDLPEVLAALETLQREGLADERVAVCGKSYGGFLSAWAIGHTDRFRAAVVMAPVADAR
CCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCCC
GHYGTSDSGYYADPFDFGGTPWSVPQAYLQRSTLPGAARARTPTLILQGEDDERCPVGQS
CCCCCCCCCEECCCCCCCCCCCCCHHHHHHHCCCCCCHHCCCCEEEEECCCCCCCCCCCC
EALFCALKRGANPPCELVIYPGEGHAFTSAGTPSVREDAVRRIVEWLARWTEPPVRPQRA
CCEEHEEHHCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]