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The map label for this gene is gluQ [H]

Identifier: 120611695

GI number: 120611695

Start: 3340692

End: 3341699

Strand: Direct

Name: gluQ [H]

Synonym: Aave_3032

Alternate gene names: 120611695

Gene position: 3340692-3341699 (Clockwise)

Preceding gene: 120611694

Following gene: 120611696

Centisome position: 62.41

GC content: 73.81

Gene sequence:

>1008_bases
ATGAGCGTCTCCCCGGCCGCATCCACGCAAGCCCCGGCCGCGGGCCGACGCTATGTAGGCCGCTTCGCGCCCTCGCCCAC
CGGCCCGCTGCATGCGGGCTCGCTGGTGGCCGCGCTGGCCAGTTGGCTGGACGCGCGCTCCGCGGACGATGGCCGCGGCG
GCATCTGGCTGGTGCGCATCGAAGACGTGGACACGCCACGCTGCCAGCCCGGCGCGGCGGAGACGATTCTGCGGCAGCTC
GCGGACTGCGGCCTCGTGCCGGACGGCACGGTGTGGTGGCAGTCGGCACGCCACGCGCGGTATGCCGAGCAGCTGGAGCA
TCTGGCGCACGCAGGGCTGGCCTACCCGTGCGCCTGCACCCGCGCGGACATCGAGCGCGCCCATCGGCTGCACCACGGCG
CGCGCGACCGCCATTCGGAGCTGCCCTATCCGGGCACCTGCCGCAACGGCCTGGGCGGGCGCCCGCCCCGGTCCTGGCGG
TTTCGCACGTCGGAATACCAGAAGAAATTTGCCCCGCAGGCCGCCGCGCAGGCGCAGGACCGCCCCGCCATCCATGCGGG
CGGCGTGGCCTGGACCGACCGGCGCCTGGGACCGCGCACGCAGGACGTGGCGGAGGTGGTGGGCGACTTCGTGCTGCGCC
GCGCGGACGGCCTCTGGGCTTACCAGCTCGCCGTGGTGGTGGACGATGCCGACCAGGGAGTGACGCACGTGGTCCGCGGG
GAAGACCTGCTGGACAACACGCCCAGGCAGATTCTTCTGCGGCACGCCCTCGGGGCCGGGGCCCCCTCCTACCTGCACAC
GCCCCTGGTGCGCGCACCGGACGGAGAGAAACTCTCCAAACAGCACGGCGCGCCGGCGGTGGACACCTCGAACCCTCTGG
CGGCGCTCCGCGCAGCGGCCGGCGCGCTGGGGCTGCCGCCTCTGCAGCATCCGCACGACACCACCGTCGGCGAGGCGCTG
GCGTGGTGGGCGCAGGCATGGCCGCGAATCTACAATCGGCCATCGTGA

Upstream 100 bases:

>100_bases
GGGACGCCGCGGCCGGCATCGGGCTGGCCGGCGACTGGTGCCTGGGCCACCGGGTCGAGGACGCGTTCGTTGCGGGGCTC
GAACTCGCGCTCGCGGTGGC

Downstream 100 bases:

>100_bases
CAGCCATGCATTCCATCCCGGCCGATACCGGCCACACCCCTTCGCGCGCGCCTGCCGGCAACGGCTCGCCGCCCGCCGAT
GTTGCCTTTCCCAAGGCGAT

Product: glutamate--tRNA ligase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSVSPAASTQAPAAGRRYVGRFAPSPTGPLHAGSLVAALASWLDARSADDGRGGIWLVRIEDVDTPRCQPGAAETILRQL
ADCGLVPDGTVWWQSARHARYAEQLEHLAHAGLAYPCACTRADIERAHRLHHGARDRHSELPYPGTCRNGLGGRPPRSWR
FRTSEYQKKFAPQAAAQAQDRPAIHAGGVAWTDRRLGPRTQDVAEVVGDFVLRRADGLWAYQLAVVVDDADQGVTHVVRG
EDLLDNTPRQILLRHALGAGAPSYLHTPLVRAPDGEKLSKQHGAPAVDTSNPLAALRAAAGALGLPPLQHPHDTTVGEAL
AWWAQAWPRIYNRPS

Sequences:

>Translated_335_residues
MSVSPAASTQAPAAGRRYVGRFAPSPTGPLHAGSLVAALASWLDARSADDGRGGIWLVRIEDVDTPRCQPGAAETILRQL
ADCGLVPDGTVWWQSARHARYAEQLEHLAHAGLAYPCACTRADIERAHRLHHGARDRHSELPYPGTCRNGLGGRPPRSWR
FRTSEYQKKFAPQAAAQAQDRPAIHAGGVAWTDRRLGPRTQDVAEVVGDFVLRRADGLWAYQLAVVVDDADQGVTHVVRG
EDLLDNTPRQILLRHALGAGAPSYLHTPLVRAPDGEKLSKQHGAPAVDTSNPLAALRAAAGALGLPPLQHPHDTTVGEAL
AWWAQAWPRIYNRPS
>Mature_334_residues
SVSPAASTQAPAAGRRYVGRFAPSPTGPLHAGSLVAALASWLDARSADDGRGGIWLVRIEDVDTPRCQPGAAETILRQLA
DCGLVPDGTVWWQSARHARYAEQLEHLAHAGLAYPCACTRADIERAHRLHHGARDRHSELPYPGTCRNGLGGRPPRSWRF
RTSEYQKKFAPQAAAQAQDRPAIHAGGVAWTDRRLGPRTQDVAEVVGDFVLRRADGLWAYQLAVVVDDADQGVTHVVRGE
DLLDNTPRQILLRHALGAGAPSYLHTPLVRAPDGEKLSKQHGAPAVDTSNPLAALRAAAGALGLPPLQHPHDTTVGEALA
WWAQAWPRIYNRPS

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=279, Percent_Identity=35.4838709677419, Blast_Score=134, Evalue=8e-32,
Organism=Escherichia coli, GI226510925, Length=311, Percent_Identity=44.3729903536978, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1788743, Length=275, Percent_Identity=35.6363636363636, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71993394, Length=295, Percent_Identity=30.1694915254237, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324540, Length=277, Percent_Identity=34.2960288808664, Blast_Score=141, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24665321, Length=286, Percent_Identity=33.2167832167832, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 36195; Mature: 36064

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSPAASTQAPAAGRRYVGRFAPSPTGPLHAGSLVAALASWLDARSADDGRGGIWLVRI
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
EDVDTPRCQPGAAETILRQLADCGLVPDGTVWWQSARHARYAEQLEHLAHAGLAYPCACT
ECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RADIERAHRLHHGARDRHSELPYPGTCRNGLGGRPPRSWRFRTSEYQKKFAPQAAAQAQD
HHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCC
RPAIHAGGVAWTDRRLGPRTQDVAEVVGDFVLRRADGLWAYQLAVVVDDADQGVTHVVRG
CCCEEECCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHCC
EDLLDNTPRQILLRHALGAGAPSYLHTPLVRAPDGEKLSKQHGAPAVDTSNPLAALRAAA
CHHHHCCHHHHHHHHHHCCCCCHHHHCCCEECCCCHHHHHHCCCCCCCCCCHHHHHHHHH
GALGLPPLQHPHDTTVGEALAWWAQAWPRIYNRPS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVSPAASTQAPAAGRRYVGRFAPSPTGPLHAGSLVAALASWLDARSADDGRGGIWLVRI
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
EDVDTPRCQPGAAETILRQLADCGLVPDGTVWWQSARHARYAEQLEHLAHAGLAYPCACT
ECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RADIERAHRLHHGARDRHSELPYPGTCRNGLGGRPPRSWRFRTSEYQKKFAPQAAAQAQD
HHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCC
RPAIHAGGVAWTDRRLGPRTQDVAEVVGDFVLRRADGLWAYQLAVVVDDADQGVTHVVRG
CCCEEECCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHCC
EDLLDNTPRQILLRHALGAGAPSYLHTPLVRAPDGEKLSKQHGAPAVDTSNPLAALRAAA
CHHHHCCHHHHHHHHHHCCCCCHHHHCCCEECCCCHHHHHHCCCCCCCCCCHHHHHHHHH
GALGLPPLQHPHDTTVGEALAWWAQAWPRIYNRPS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA