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The map label for this gene is luxQ [H]

Identifier: 120611638

GI number: 120611638

Start: 3264540

End: 3266531

Strand: Direct

Name: luxQ [H]

Synonym: Aave_2975

Alternate gene names: 120611638

Gene position: 3264540-3266531 (Clockwise)

Preceding gene: 120611637

Following gene: 120611639

Centisome position: 60.99

GC content: 70.18

Gene sequence:

>1992_bases
ATGCTCGACGTCGGAGCCATCCACGCGACCATCGAACGCTCGGCCCACACCGTGCTGGTGGTGGACGACAACCCGGTCAC
CCGCTATTCCACCGCGCGCGTCGTGCGCGCGGCGGGCTTCCAGACCATGGAAGCCGAGAGCGGCGCACAGGCCCTGCAGA
TGGCGGGCGAAGGCATCTCGGCCGTGGTGCTGGACGTGCACCTGCCGGACATCGACGGCTTCGCCGTCTGCCGCGCGCTG
CGCACCCGCGAAGACACGGCCCAGTTGCCCGTGATGCACCTTTCGGCGGCCCACGTGCATGCCGAGGACCGCGTCACCGG
GCTGAACGCCGGGGCCGACGCCTACCTCACCCATCCCGTGGAACCCGCGGTGCTGGTGGGCACCCTGCAGGCACTCATCC
GCGCGCGCACTGCGGAGGACAGCCTGCGGCGCAGCGACCGGCGCTTCCGCGCCATCTACAGCCAGGCCCTCAGCGGCATC
GGGCTGCTGGAGCGCGACGGGCGCTTCACCGACGTCAACCCGGCGATGGCGCGCGTGCTCGGGCGCACCCGCCAGGAAGT
CCTCGGCCGCGCGATCAGCGACTTCGCCCCGCCCGGCTGGGTGGACTTCGTCAAGGACAAGACGGTGGACACCGGCCAGT
CGGCCACCTGGCAGGGCGAGTTCCCGCTCATGCGGCCCTCGGGCCAATGGGTGTACCTGGAATGGAGCATTTCCGCGCAC
GTGGAACCCGGGATGCGCATGGCCCTGGCCGCCGACATCTCCGAGCGGGTGGAACTCGACAGCCGCCGCCAGGAGGTGCT
GGAGCGCGAGCAGGCGGCCCGCGCCACGGCCGAGCGCCTGAGCCGCACCAAGGACGACTTCATCGCCGTGCTGTCGCACG
AGTTGCGCACGCCGCTGAACGCGATCGCCGGCTGGGTGCACATCCTCAAGCGGCGCGGCGGCACGCCGGAACTCATCAAG
GGCCTGGATTCCATCCACCGCAACGTCAAGGCGCAGGCGCGCATCATCTCCGACATCCTCGACGTCTCGCGCATCAACAG
CGGCAAGCTGCACCTGGAGCGCGAGTGGACGCAGCCCATCGAGGTGGTGCGCTCCGCGATCGATGCGCTGCAGGCCTCCA
TCGCCGAGAAGCACCTCGAGATCGTGCTGCGCGCAGGCGAGGACATCGGTCCCGCCTGGCTCGACCCGACGCGGTTCCAG
CAGATCTTCTGGAACCTGCTGACCAACGCCATCAAGTTCTCGAACGACAGCGGGCGCATCGACGTGTCGCTGTCCCGCGA
TGACGATGCGCTCACGCTGACCGTGCAGGATTTCGGACGCGGCATCTCGCCCGAATTCATCGAGCACCTCTTCGACCGGT
TCACCCAGAGCGATTCACCGGACAACCGCCGCCACGGCGGTTTGGGCCTCGGCCTGTCCATCGTCAAGCATCTGGCGGAA
CTGCATGGTGGCGGCGCCGAGGCCTACAGCGCCGGAACCGGAGAAGGCACCACGATCACGGTCACGCTCACCGCGGCCTA
CGAAGGCGGCGCCAGCGCGAGCGTGCCTGCGGCGCTGGCGTCCGACGAGCCGGCCCCGGAGCCGGCCGAGGCCGAGCGTC
CGCTCAGGGGCCTGGACATCCTCACCGTCGAAGACCACCCGGACGCGAGCGAAATGCTGGCCGTCGTCCTTTCGGACGGA
GGCGCCCGGCCCCGGCAGGCGGTGGATTTCGACTCCGCGATGCAAGCGCTGCGCGAACGCTGGCCCGACGTGGTCGTGAG
CGACATCGGCCTGCCCGGGCGCGACGGCTACGAACTCGCGCGGGCGCTGCGCGACATGCCCGTGCCGCAAGGGCTCAAGC
CGCCCATCGCGATCGCGCTCACCGCGTTTTCGCGCCCGCAGGACGCGAACAAGGCTCTGGAAGCGGGTTTCGACGCACAC
CTGGGCAAGCCCCTGCAGCCCCATGCCCTGATGGCCACGATCGCGCGCCTGATGGCCGCCCGCCCGGCCTAG

Upstream 100 bases:

>100_bases
AGCTGCAGAGCGTGCCCGGCGAAGGATCGGTGTTCTCCGTGACGCTGCCCGTGCGCCTGCCGGAGCCGGCGCCTGCCACC
GGGATCGCGGAGTGACGCAT

Downstream 100 bases:

>100_bases
ACACCGACGTCCCCTGACGCCATGACGATCCCACCGACCCCGCCCGCCGAGCGCCATGCCGACATCTTCATCGGCCAGAG
CGAGATGGCACGGCGCATGC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MLDVGAIHATIERSAHTVLVVDDNPVTRYSTARVVRAAGFQTMEAESGAQALQMAGEGISAVVLDVHLPDIDGFAVCRAL
RTREDTAQLPVMHLSAAHVHAEDRVTGLNAGADAYLTHPVEPAVLVGTLQALIRARTAEDSLRRSDRRFRAIYSQALSGI
GLLERDGRFTDVNPAMARVLGRTRQEVLGRAISDFAPPGWVDFVKDKTVDTGQSATWQGEFPLMRPSGQWVYLEWSISAH
VEPGMRMALAADISERVELDSRRQEVLEREQAARATAERLSRTKDDFIAVLSHELRTPLNAIAGWVHILKRRGGTPELIK
GLDSIHRNVKAQARIISDILDVSRINSGKLHLEREWTQPIEVVRSAIDALQASIAEKHLEIVLRAGEDIGPAWLDPTRFQ
QIFWNLLTNAIKFSNDSGRIDVSLSRDDDALTLTVQDFGRGISPEFIEHLFDRFTQSDSPDNRRHGGLGLGLSIVKHLAE
LHGGGAEAYSAGTGEGTTITVTLTAAYEGGASASVPAALASDEPAPEPAEAERPLRGLDILTVEDHPDASEMLAVVLSDG
GARPRQAVDFDSAMQALRERWPDVVVSDIGLPGRDGYELARALRDMPVPQGLKPPIAIALTAFSRPQDANKALEAGFDAH
LGKPLQPHALMATIARLMAARPA

Sequences:

>Translated_663_residues
MLDVGAIHATIERSAHTVLVVDDNPVTRYSTARVVRAAGFQTMEAESGAQALQMAGEGISAVVLDVHLPDIDGFAVCRAL
RTREDTAQLPVMHLSAAHVHAEDRVTGLNAGADAYLTHPVEPAVLVGTLQALIRARTAEDSLRRSDRRFRAIYSQALSGI
GLLERDGRFTDVNPAMARVLGRTRQEVLGRAISDFAPPGWVDFVKDKTVDTGQSATWQGEFPLMRPSGQWVYLEWSISAH
VEPGMRMALAADISERVELDSRRQEVLEREQAARATAERLSRTKDDFIAVLSHELRTPLNAIAGWVHILKRRGGTPELIK
GLDSIHRNVKAQARIISDILDVSRINSGKLHLEREWTQPIEVVRSAIDALQASIAEKHLEIVLRAGEDIGPAWLDPTRFQ
QIFWNLLTNAIKFSNDSGRIDVSLSRDDDALTLTVQDFGRGISPEFIEHLFDRFTQSDSPDNRRHGGLGLGLSIVKHLAE
LHGGGAEAYSAGTGEGTTITVTLTAAYEGGASASVPAALASDEPAPEPAEAERPLRGLDILTVEDHPDASEMLAVVLSDG
GARPRQAVDFDSAMQALRERWPDVVVSDIGLPGRDGYELARALRDMPVPQGLKPPIAIALTAFSRPQDANKALEAGFDAH
LGKPLQPHALMATIARLMAARPA
>Mature_663_residues
MLDVGAIHATIERSAHTVLVVDDNPVTRYSTARVVRAAGFQTMEAESGAQALQMAGEGISAVVLDVHLPDIDGFAVCRAL
RTREDTAQLPVMHLSAAHVHAEDRVTGLNAGADAYLTHPVEPAVLVGTLQALIRARTAEDSLRRSDRRFRAIYSQALSGI
GLLERDGRFTDVNPAMARVLGRTRQEVLGRAISDFAPPGWVDFVKDKTVDTGQSATWQGEFPLMRPSGQWVYLEWSISAH
VEPGMRMALAADISERVELDSRRQEVLEREQAARATAERLSRTKDDFIAVLSHELRTPLNAIAGWVHILKRRGGTPELIK
GLDSIHRNVKAQARIISDILDVSRINSGKLHLEREWTQPIEVVRSAIDALQASIAEKHLEIVLRAGEDIGPAWLDPTRFQ
QIFWNLLTNAIKFSNDSGRIDVSLSRDDDALTLTVQDFGRGISPEFIEHLFDRFTQSDSPDNRRHGGLGLGLSIVKHLAE
LHGGGAEAYSAGTGEGTTITVTLTAAYEGGASASVPAALASDEPAPEPAEAERPLRGLDILTVEDHPDASEMLAVVLSDG
GARPRQAVDFDSAMQALRERWPDVVVSDIGLPGRDGYELARALRDMPVPQGLKPPIAIALTAFSRPQDANKALEAGFDAH
LGKPLQPHALMATIARLMAARPA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=417, Percent_Identity=29.9760191846523, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI48994928, Length=578, Percent_Identity=28.2006920415225, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=34.8314606741573, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=36.4035087719298, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081816, Length=363, Percent_Identity=29.2011019283747, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=30.6201550387597, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=29.8701298701299, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=31.0502283105023, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788549, Length=392, Percent_Identity=23.469387755102, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=27.6422764227642, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=212, Percent_Identity=31.6037735849057, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1786599, Length=125, Percent_Identity=36.8, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=25.4385964912281, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790861, Length=243, Percent_Identity=29.2181069958848, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787894, Length=278, Percent_Identity=27.6978417266187, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=23.6111111111111, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1789809, Length=128, Percent_Identity=33.59375, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=33.8842975206612, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787375, Length=118, Percent_Identity=35.5932203389831, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789403, Length=210, Percent_Identity=27.1428571428571, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=24.0909090909091, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI1790551, Length=213, Percent_Identity=29.1079812206573, Blast_Score=63, Evalue=8e-11,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=28.5067873303167, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72014; Mature: 72014

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVGAIHATIERSAHTVLVVDDNPVTRYSTARVVRAAGFQTMEAESGAQALQMAGEGIS
CCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCE
AVVLDVHLPDIDGFAVCRALRTREDTAQLPVMHLSAAHVHAEDRVTGLNAGADAYLTHPV
EEEEEEECCCCCHHHHHHHHHCCCHHHCCCHHEEHHHHCCHHHCCCCCCCCCCCEEECCC
EPAVLVGTLQALIRARTAEDSLRRSDRRFRAIYSQALSGIGLLERDGRFTDVNPAMARVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHH
GRTRQEVLGRAISDFAPPGWVDFVKDKTVDTGQSATWQGEFPLMRPSGQWVYLEWSISAH
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEECCCCCEECCCCCEEEEEEEEEEC
VEPGMRMALAADISERVELDSRRQEVLEREQAARATAERLSRTKDDFIAVLSHELRTPLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHH
AIAGWVHILKRRGGTPELIKGLDSIHRNVKAQARIISDILDVSRINSGKLHLEREWTQPI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
EVVRSAIDALQASIAEKHLEIVLRAGEDIGPAWLDPTRFQQIFWNLLTNAIKFSNDSGRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
DVSLSRDDDALTLTVQDFGRGISPEFIEHLFDRFTQSDSPDNRRHGGLGLGLSIVKHLAE
EEEECCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
LHGGGAEAYSAGTGEGTTITVTLTAAYEGGASASVPAALASDEPAPEPAEAERPLRGLDI
HCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHCCCCCCCCCCHHCCCCCCCEE
LTVEDHPDASEMLAVVLSDGGARPRQAVDFDSAMQALRERWPDVVVSDIGLPGRDGYELA
EEECCCCCHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHCCCCEEHHCCCCCCCHHHHH
RALRDMPVPQGLKPPIAIALTAFSRPQDANKALEAGFDAHLGKPLQPHALMATIARLMAA
HHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHC
RPA
CCC
>Mature Secondary Structure
MLDVGAIHATIERSAHTVLVVDDNPVTRYSTARVVRAAGFQTMEAESGAQALQMAGEGIS
CCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCE
AVVLDVHLPDIDGFAVCRALRTREDTAQLPVMHLSAAHVHAEDRVTGLNAGADAYLTHPV
EEEEEEECCCCCHHHHHHHHHCCCHHHCCCHHEEHHHHCCHHHCCCCCCCCCCCEEECCC
EPAVLVGTLQALIRARTAEDSLRRSDRRFRAIYSQALSGIGLLERDGRFTDVNPAMARVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHH
GRTRQEVLGRAISDFAPPGWVDFVKDKTVDTGQSATWQGEFPLMRPSGQWVYLEWSISAH
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEECCCCCEECCCCCEEEEEEEEEEC
VEPGMRMALAADISERVELDSRRQEVLEREQAARATAERLSRTKDDFIAVLSHELRTPLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHH
AIAGWVHILKRRGGTPELIKGLDSIHRNVKAQARIISDILDVSRINSGKLHLEREWTQPI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
EVVRSAIDALQASIAEKHLEIVLRAGEDIGPAWLDPTRFQQIFWNLLTNAIKFSNDSGRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
DVSLSRDDDALTLTVQDFGRGISPEFIEHLFDRFTQSDSPDNRRHGGLGLGLSIVKHLAE
EEEECCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
LHGGGAEAYSAGTGEGTTITVTLTAAYEGGASASVPAALASDEPAPEPAEAERPLRGLDI
HCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHCCCCCCCCCCHHCCCCCCCEE
LTVEDHPDASEMLAVVLSDGGARPRQAVDFDSAMQALRERWPDVVVSDIGLPGRDGYELA
EEECCCCCHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHCCCCEEHHCCCCCCCHHHHH
RALRDMPVPQGLKPPIAIALTAFSRPQDANKALEAGFDAHLGKPLQPHALMATIARLMAA
HHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHC
RPA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA