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The map label for this gene is rsbS [H]

Identifier: 120611634

GI number: 120611634

Start: 3261768

End: 3262142

Strand: Direct

Name: rsbS [H]

Synonym: Aave_2971

Alternate gene names: 120611634

Gene position: 3261768-3262142 (Clockwise)

Preceding gene: 120611633

Following gene: 120611635

Centisome position: 60.94

GC content: 66.93

Gene sequence:

>375_bases
ATGGAACGCATACCGATCCTCCGCATGGGCAACACCCTGCTGGTCACCATCCAGGTGGACATGCAGGACCGCACCGCCCT
CGCGCTGCAGGAAGACCTCGCCACGCGCATCGCCGACACCGGCGCGACGGGCGTGATGATCGACATCTCCGGACTGGAGA
TCGTGGATTCGTTCGTGGGCCGGATGCTCAGCAGCATCTCCGGCATCGCGCGCATTCTCTCGGCACATACGGTCGTGGTC
GGCATGCAGCCGGCCGTGGCCATCACCCTGGTGGAACTCGGCCTGTCGCTGGACGGCGTGCGCACCGCGCTCAACGTGGA
GCGCGGCATGGAACTGCTGCGCCGCATCCGCGAGGAGGCCCCTCTTGGCCGATGA

Upstream 100 bases:

>100_bases
ACACGCGCGCCACGCTCGCGGACGCGCTCGCCCTCGCGCTGCAGAAAAGCGGCTGGCGCATCGAGCGCGACCGCGCGCCC
ACCTGAGCGGAAGGACACGC

Downstream 100 bases:

>100_bases
CACCTCGGGCACCCTGCCCCTCGAATCCGAGCAGCACATCGTGCTGTGCCGCCAGGCCGTCCGCACGCTGTGCGGCAGGC
TCCGGTTCTCGCTGGTGGAC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MERIPILRMGNTLLVTIQVDMQDRTALALQEDLATRIADTGATGVMIDISGLEIVDSFVGRMLSSISGIARILSAHTVVV
GMQPAVAITLVELGLSLDGVRTALNVERGMELLRRIREEAPLGR

Sequences:

>Translated_124_residues
MERIPILRMGNTLLVTIQVDMQDRTALALQEDLATRIADTGATGVMIDISGLEIVDSFVGRMLSSISGIARILSAHTVVV
GMQPAVAITLVELGLSLDGVRTALNVERGMELLRRIREEAPLGR
>Mature_124_residues
MERIPILRMGNTLLVTIQVDMQDRTALALQEDLATRIADTGATGVMIDISGLEIVDSFVGRMLSSISGIARILSAHTVVV
GMQPAVAITLVELGLSLDGVRTALNVERGMELLRRIREEAPLGR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 13366; Mature: 13366

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIPILRMGNTLLVTIQVDMQDRTALALQEDLATRIADTGATGVMIDISGLEIVDSFVG
CCCCCEEEECCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHH
RMLSSISGIARILSAHTVVVGMQPAVAITLVELGLSLDGVRTALNVERGMELLRRIREEA
HHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
PLGR
CCCC
>Mature Secondary Structure
MERIPILRMGNTLLVTIQVDMQDRTALALQEDLATRIADTGATGVMIDISGLEIVDSFVG
CCCCCEEEECCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHH
RMLSSISGIARILSAHTVVVGMQPAVAITLVELGLSLDGVRTALNVERGMELLRRIREEA
HHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
PLGR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]