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The map label for this gene is yncB [H]

Identifier: 120611535

GI number: 120611535

Start: 3161493

End: 3162509

Strand: Reverse

Name: yncB [H]

Synonym: Aave_2871

Alternate gene names: 120611535

Gene position: 3162509-3161493 (Counterclockwise)

Preceding gene: 120611536

Following gene: 120611534

Centisome position: 59.08

GC content: 69.12

Gene sequence:

>1017_bases
ATGCCACGCAACCAGCAGATCCTCCTGGACAGCCGCCCGCAGGGCGAAGCCACCACCGGCAACTTCAAGCTCGTCGCCAC
CGACACGCCCGCGCTGCAGGACGGCCAGGTGCTCGTGCGCCACCATTACCTGAGCCTGGACCCGTACATGCGCGGCCGCA
TGAACGACAGCAAGAGCTACGCCGCGTCCCAGCCCCTGGGCGAGGTCATGATCGGCGGCACCGTCGGCGAAGTGGCGGAA
AGCCGCCACCCCAAGTTCGCCGTGGGCGACAAGGTCGTCGGCATGGGCGGCTGGCAGGAGTGGAGCGTGGTGGACGGCAA
CGCGCCCGGCATGCTGCGCAAGGTGGACACCACCCACGTGCCGCTGTCGCACTACCTCGGAGCGGTGGGCATGCCCGGCG
TGACCGCCTGGTACGGCCTCGTGAAGATCATCGAGCCCAAGGCCGGCGAAACCATGGTGGTCAGCGCGGCCTCCGGCGCC
GTGGGCAGCGCGTTCGGTGCCCTCGCCAAGGCGCGCGGCTGCCGCGTGGTGGGCATCGCCGGCGGCCCCGACAAGTGCCG
CTACGTGACCGAGGAACTGGGCTTCGACGCCTGCATCGACCATCGCGAGCACGGCGACCTCAAGAGCATGTCCCAGGCGC
TGAAGCAGGCCTGCCCCCAGGGCATCGACGGCTACTTCGAGAATGTCGGCGGCTACATCCTCGACGCCGTGCTGCTGCGC
GCCAACGCCTTCGCGCGGGTGGCCGTGTGCGGCATGATCGCCGGCTACGACGGCCAGCCCCTGCCGCTGCAGAACCCGGC
CCTCATCCTCATCAACCGCATGAAGGTGCAGGGTTTCATCGTCAGCGAGCACATGGAGATCTGGCCCGAGGCCCTCAAGG
AGCTGGGCGGGCTCGTCGGCTCCGGCAAGCTGCGTCCGCGCGAGACGATCGCGGAGAGCATCGCCGCCGCGCCGGAAGCC
TTCCTCGGCCTGCTCAAGGGCAAGAACTTCGGCAAGCAGCTGGTCAAGCTGGTCTGA

Upstream 100 bases:

>100_bases
TTCAAATACATGAAGCGGCCCGCACAGCCCGCGGCATCGGTTCCTACCGACTGACCCGTTTCCCTGCGTATTTCCCGTTT
TACCGAAAAAGGAGAACTCC

Downstream 100 bases:

>100_bases
TGGCCGCGCCGCTGCTCTGGCACTGGTCCCGCTTCGACGATCTCGGCGTGCATGCGCTGCACGACGCGCTCGCCCTGCGC
TGCCGCGTGTTCATCCTGGA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MPRNQQILLDSRPQGEATTGNFKLVATDTPALQDGQVLVRHHYLSLDPYMRGRMNDSKSYAASQPLGEVMIGGTVGEVAE
SRHPKFAVGDKVVGMGGWQEWSVVDGNAPGMLRKVDTTHVPLSHYLGAVGMPGVTAWYGLVKIIEPKAGETMVVSAASGA
VGSAFGALAKARGCRVVGIAGGPDKCRYVTEELGFDACIDHREHGDLKSMSQALKQACPQGIDGYFENVGGYILDAVLLR
ANAFARVAVCGMIAGYDGQPLPLQNPALILINRMKVQGFIVSEHMEIWPEALKELGGLVGSGKLRPRETIAESIAAAPEA
FLGLLKGKNFGKQLVKLV

Sequences:

>Translated_338_residues
MPRNQQILLDSRPQGEATTGNFKLVATDTPALQDGQVLVRHHYLSLDPYMRGRMNDSKSYAASQPLGEVMIGGTVGEVAE
SRHPKFAVGDKVVGMGGWQEWSVVDGNAPGMLRKVDTTHVPLSHYLGAVGMPGVTAWYGLVKIIEPKAGETMVVSAASGA
VGSAFGALAKARGCRVVGIAGGPDKCRYVTEELGFDACIDHREHGDLKSMSQALKQACPQGIDGYFENVGGYILDAVLLR
ANAFARVAVCGMIAGYDGQPLPLQNPALILINRMKVQGFIVSEHMEIWPEALKELGGLVGSGKLRPRETIAESIAAAPEA
FLGLLKGKNFGKQLVKLV
>Mature_337_residues
PRNQQILLDSRPQGEATTGNFKLVATDTPALQDGQVLVRHHYLSLDPYMRGRMNDSKSYAASQPLGEVMIGGTVGEVAES
RHPKFAVGDKVVGMGGWQEWSVVDGNAPGMLRKVDTTHVPLSHYLGAVGMPGVTAWYGLVKIIEPKAGETMVVSAASGAV
GSAFGALAKARGCRVVGIAGGPDKCRYVTEELGFDACIDHREHGDLKSMSQALKQACPQGIDGYFENVGGYILDAVLLRA
NAFARVAVCGMIAGYDGQPLPLQNPALILINRMKVQGFIVSEHMEIWPEALKELGGLVGSGKLRPRETIAESIAAAPEAF
LGLLKGKNFGKQLVKLV

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=339, Percent_Identity=36.5781710914454, Blast_Score=205, Evalue=4e-53,
Organism=Homo sapiens, GI226059133, Length=339, Percent_Identity=36.5781710914454, Blast_Score=205, Evalue=4e-53,
Organism=Homo sapiens, GI226246682, Length=348, Percent_Identity=37.0689655172414, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI226246680, Length=348, Percent_Identity=37.0689655172414, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI22748929, Length=348, Percent_Identity=37.0689655172414, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI226056130, Length=283, Percent_Identity=36.0424028268551, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI28557745, Length=368, Percent_Identity=27.1739130434783, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI226510941, Length=343, Percent_Identity=45.7725947521866, Blast_Score=293, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI133901710, Length=355, Percent_Identity=31.830985915493, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI133901712, Length=355, Percent_Identity=31.830985915493, Blast_Score=163, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6323504, Length=337, Percent_Identity=29.3768545994065, Blast_Score=126, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36007; Mature: 35876

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRNQQILLDSRPQGEATTGNFKLVATDTPALQDGQVLVRHHYLSLDPYMRGRMNDSKSY
CCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCHHHHCCCCCCCHH
AASQPLGEVMIGGTVGEVAESRHPKFAVGDKVVGMGGWQEWSVVDGNAPGMLRKVDTTHV
HHCCCCCCEEECCCHHHHHHCCCCCEECCCEEEECCCCCCCEEECCCCCCCEEECCCCCC
PLSHYLGAVGMPGVTAWYGLVKIIEPKAGETMVVSAASGAVGSAFGALAKARGCRVVGIA
CHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEC
GGPDKCRYVTEELGFDACIDHREHGDLKSMSQALKQACPQGIDGYFENVGGYILDAVLLR
CCCHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ANAFARVAVCGMIAGYDGQPLPLQNPALILINRMKVQGFIVSEHMEIWPEALKELGGLVG
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHCCCCC
SGKLRPRETIAESIAAAPEAFLGLLKGKNFGKQLVKLV
CCCCCHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
PRNQQILLDSRPQGEATTGNFKLVATDTPALQDGQVLVRHHYLSLDPYMRGRMNDSKSY
CCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCHHHHCCCCCCCHH
AASQPLGEVMIGGTVGEVAESRHPKFAVGDKVVGMGGWQEWSVVDGNAPGMLRKVDTTHV
HHCCCCCCEEECCCHHHHHHCCCCCEECCCEEEECCCCCCCEEECCCCCCCEEECCCCCC
PLSHYLGAVGMPGVTAWYGLVKIIEPKAGETMVVSAASGAVGSAFGALAKARGCRVVGIA
CHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEC
GGPDKCRYVTEELGFDACIDHREHGDLKSMSQALKQACPQGIDGYFENVGGYILDAVLLR
CCCHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ANAFARVAVCGMIAGYDGQPLPLQNPALILINRMKVQGFIVSEHMEIWPEALKELGGLVG
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHCCCCC
SGKLRPRETIAESIAAAPEAFLGLLKGKNFGKQLVKLV
CCCCCHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]