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The map label for this gene is yfdE [H]

Identifier: 120610661

GI number: 120610661

Start: 2149672

End: 2150949

Strand: Reverse

Name: yfdE [H]

Synonym: Aave_1981

Alternate gene names: 120610661

Gene position: 2150949-2149672 (Counterclockwise)

Preceding gene: 120610662

Following gene: 120610660

Centisome position: 40.18

GC content: 71.91

Gene sequence:

>1278_bases
ATGGACGCGGCTCCCCTGCCCTCCCCCGCGCCCGCGGCCGGCGCGCTCGCCGGTATCCGGGTACTCGACCTCTCGCGCGT
GCTGGCCGGACCGTGGTGCACCCAGGTACTGGCCGACCTGGGCGCGGACGTGGTCAAGGTCGAGCGCCCCGGCCTGGGTG
ACGATACGCGCCAGTGGGGCCCGCCGTTCCTGAAGGATGCCCAGGGCCGCGAGACGGACCAGGCGGCCTACTTCACGGCC
TGCAACCGCAACAAGCGCTCCATCACCATCGACATGGCCCACCCGGAAGGCCAGGCACTGATCCGTGCCATGGCGCTGCG
GGCGGACGTGGTGGTGGAAAACTTCAAGGTGGGCGGGCTGAAGCAGTACGGGCTGGACCACGAGAGCCTGCGGGCCCTGA
ACCCGCGGCTCATCTACTGCTCGGTGACGGGCTTCGGGCAGGACGGCCCCTATGCCGCCCGGGCCGGCTACGACCTGATG
GTGCAGGCCTTGACCGGCCTGATGGACATCACGGGCCGGGCGGACGGCGAACCCGGCGGCGGCCCGCTACGGGTGGGCGT
GGCGGTGATCGACCTGTTCACGGGCCTGTATGCCAGCAATGCCATCCTGGCAGCACTGCATGCCAGGCAGCACACTGGCG
AGGGCCAGCACATCGACATGGCCCTGCTGGACGTGGGCATGGCCGTGCTGGCCAACCAGGCCGCGGGTTTCCTGGCCACC
GGGGAATCGCCGCGGCGCCAGGGCAACAGCCACCCGAGCCTGGTGCCCTACCAGGACTTTCCCACGGCCGACGGCGCCAT
GCTGCTGGCCATCGGCAACGACGGCCAGTTCGCGCGCTTCTGCACGGCCGCCGGCCGGCCGGAATGGGCATCGGACGCGC
GGTTCAGGACCAATACCCTGCGCGTGGTGCACCGCGCCGAACTGGTGCCGCTGATGGAGTCGGTGACCCGCACGCGCAGC
ACCGCGGAATGGGTGGCGCTGCTGGAGGACAAGGCCGTGCCGTGCGGGCCGATCAATAGCATCGCCCAGGCGTTCAATGA
TCCGCAGGTGCGCGCGCGCGGGCTCGCCGTGGAGCTTCCGCGCCGGCCGGACGGCAGTGCAGGTGCCGATGGCATCGCCA
CCGTGCGCGGCGTCGCCAGCCCGTTGCGGCTGTCGGCCACGCCGCCCGTGCTGCGCCATGCGCCGCCCGCGCTGGGGCAG
CATACCGAAGAGATTCTGGCGGACATGGGGCTGGACGCGGCCGCCGTGGCCCGTCTGCGCGGCGCGGGGGTGGTGTAG

Upstream 100 bases:

>100_bases
CTGGAGGTGGTCAACACCTACGAGGGCACGCACGACGTGCATGCGCTCATCCTGGGCCGCGCCCAGACGGGCATCGCCGC
GTTCGCGAACTGACGGCGCC

Downstream 100 bases:

>100_bases
CCGTCCGGCTGCCGCGCGGATCGCGGCACGGGCCGACAGACGGCCTGGATGGAAGTCAACCAGAATACGGGGCGACGCGT
CATATTGCCGTCATCCTTCG

Product: formyl-CoA transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MDAAPLPSPAPAAGALAGIRVLDLSRVLAGPWCTQVLADLGADVVKVERPGLGDDTRQWGPPFLKDAQGRETDQAAYFTA
CNRNKRSITIDMAHPEGQALIRAMALRADVVVENFKVGGLKQYGLDHESLRALNPRLIYCSVTGFGQDGPYAARAGYDLM
VQALTGLMDITGRADGEPGGGPLRVGVAVIDLFTGLYASNAILAALHARQHTGEGQHIDMALLDVGMAVLANQAAGFLAT
GESPRRQGNSHPSLVPYQDFPTADGAMLLAIGNDGQFARFCTAAGRPEWASDARFRTNTLRVVHRAELVPLMESVTRTRS
TAEWVALLEDKAVPCGPINSIAQAFNDPQVRARGLAVELPRRPDGSAGADGIATVRGVASPLRLSATPPVLRHAPPALGQ
HTEEILADMGLDAAAVARLRGAGVV

Sequences:

>Translated_425_residues
MDAAPLPSPAPAAGALAGIRVLDLSRVLAGPWCTQVLADLGADVVKVERPGLGDDTRQWGPPFLKDAQGRETDQAAYFTA
CNRNKRSITIDMAHPEGQALIRAMALRADVVVENFKVGGLKQYGLDHESLRALNPRLIYCSVTGFGQDGPYAARAGYDLM
VQALTGLMDITGRADGEPGGGPLRVGVAVIDLFTGLYASNAILAALHARQHTGEGQHIDMALLDVGMAVLANQAAGFLAT
GESPRRQGNSHPSLVPYQDFPTADGAMLLAIGNDGQFARFCTAAGRPEWASDARFRTNTLRVVHRAELVPLMESVTRTRS
TAEWVALLEDKAVPCGPINSIAQAFNDPQVRARGLAVELPRRPDGSAGADGIATVRGVASPLRLSATPPVLRHAPPALGQ
HTEEILADMGLDAAAVARLRGAGVV
>Mature_425_residues
MDAAPLPSPAPAAGALAGIRVLDLSRVLAGPWCTQVLADLGADVVKVERPGLGDDTRQWGPPFLKDAQGRETDQAAYFTA
CNRNKRSITIDMAHPEGQALIRAMALRADVVVENFKVGGLKQYGLDHESLRALNPRLIYCSVTGFGQDGPYAARAGYDLM
VQALTGLMDITGRADGEPGGGPLRVGVAVIDLFTGLYASNAILAALHARQHTGEGQHIDMALLDVGMAVLANQAAGFLAT
GESPRRQGNSHPSLVPYQDFPTADGAMLLAIGNDGQFARFCTAAGRPEWASDARFRTNTLRVVHRAELVPLMESVTRTRS
TAEWVALLEDKAVPCGPINSIAQAFNDPQVRARGLAVELPRRPDGSAGADGIATVRGVASPLRLSATPPVLRHAPPALGQ
HTEEILADMGLDAAAVARLRGAGVV

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=411, Percent_Identity=42.8223844282238, Blast_Score=328, Evalue=4e-90,
Organism=Homo sapiens, GI300863124, Length=429, Percent_Identity=41.025641025641, Blast_Score=316, Evalue=2e-86,
Organism=Homo sapiens, GI13376042, Length=429, Percent_Identity=37.995337995338, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI300863126, Length=411, Percent_Identity=37.2262773722628, Blast_Score=269, Evalue=4e-72,
Organism=Homo sapiens, GI42794625, Length=413, Percent_Identity=28.0871670702179, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI266456254, Length=413, Percent_Identity=28.0871670702179, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI266458393, Length=266, Percent_Identity=34.9624060150376, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI266458397, Length=266, Percent_Identity=34.9624060150376, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI266458395, Length=152, Percent_Identity=38.8157894736842, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI42822893, Length=152, Percent_Identity=38.8157894736842, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI87082093, Length=396, Percent_Identity=35.6060606060606, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1788717, Length=429, Percent_Identity=32.1678321678322, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1786222, Length=425, Percent_Identity=24.2352941176471, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115535051, Length=261, Percent_Identity=26.8199233716475, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32564160, Length=219, Percent_Identity=26.9406392694064, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648431, Length=411, Percent_Identity=45.2554744525547, Blast_Score=346, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24585488, Length=324, Percent_Identity=27.4691358024691, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 44771; Mature: 44771

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAPLPSPAPAAGALAGIRVLDLSRVLAGPWCTQVLADLGADVVKVERPGLGDDTRQWG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCHHCC
PPFLKDAQGRETDQAAYFTACNRNKRSITIDMAHPEGQALIRAMALRADVVVENFKVGGL
CCHHCCCCCCCCCCHHEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
KQYGLDHESLRALNPRLIYCSVTGFGQDGPYAARAGYDLMVQALTGLMDITGRADGEPGG
HHHCCCHHHHHHCCCEEEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
GPLRVGVAVIDLFTGLYASNAILAALHARQHTGEGQHIDMALLDVGMAVLANQAAGFLAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCEEEC
GESPRRQGNSHPSLVPYQDFPTADGAMLLAIGNDGQFARFCTAAGRPEWASDARFRTNTL
CCCHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCCEEHHHH
RVVHRAELVPLMESVTRTRSTAEWVALLEDKAVPCGPINSIAQAFNDPQVRARGLAVELP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHCCEEEECC
RRPDGSAGADGIATVRGVASPLRLSATPPVLRHAPPALGQHTEEILADMGLDAAAVARLR
CCCCCCCCCCHHHHHHHCCCCCEECCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHH
GAGVV
CCCCC
>Mature Secondary Structure
MDAAPLPSPAPAAGALAGIRVLDLSRVLAGPWCTQVLADLGADVVKVERPGLGDDTRQWG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCHHCC
PPFLKDAQGRETDQAAYFTACNRNKRSITIDMAHPEGQALIRAMALRADVVVENFKVGGL
CCHHCCCCCCCCCCHHEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
KQYGLDHESLRALNPRLIYCSVTGFGQDGPYAARAGYDLMVQALTGLMDITGRADGEPGG
HHHCCCHHHHHHCCCEEEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
GPLRVGVAVIDLFTGLYASNAILAALHARQHTGEGQHIDMALLDVGMAVLANQAAGFLAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCEEEC
GESPRRQGNSHPSLVPYQDFPTADGAMLLAIGNDGQFARFCTAAGRPEWASDARFRTNTL
CCCHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCCEEHHHH
RVVHRAELVPLMESVTRTRSTAEWVALLEDKAVPCGPINSIAQAFNDPQVRARGLAVELP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHCCEEEECC
RRPDGSAGADGIATVRGVASPLRLSATPPVLRHAPPALGQHTEEILADMGLDAAAVARLR
CCCCCCCCCCHHHHHHHCCCCCEECCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHH
GAGVV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]