Click here to switch to the map view.

The map label for this gene is pcnB [H]

Identifier: 120610653

GI number: 120610653

Start: 2142479

End: 2144074

Strand: Direct

Name: pcnB [H]

Synonym: Aave_1973

Alternate gene names: 120610653

Gene position: 2142479-2144074 (Clockwise)

Preceding gene: 120610652

Following gene: 120610654

Centisome position: 40.03

GC content: 70.8

Gene sequence:

>1596_bases
ATGATCAAGAAGTTCATCGACAAGCTGCTCGGCAAGGCCGCGCCGGGCACGGGCCGTGGGAAACACCGCTTCGGCAAGCG
CGAGGACGTGCCCGCCTCCGTGCACGGTATCGACCCGGAACTCGTGGACCGCCGCGCCACCGAGGTGGTGCGCACGCTGC
AGCAGGCCGGCTACGAGGCCTACATCGTCGGCGGCGCCGTGCGCGACCTGCTGCTGGGCCTCAAGCCCAAGGACTTCGAC
GTGGCCACCAACGCCACGCCGGAACAGGTCAAGGGCCTGTTCCGCCGGGCCTTCATCATCGGCAAGCGCTTCCGCATCGT
GCACGTGGTGCATGGCCGCGGCCGCGAGCACGAGGTGATCGAGGTCTCCACCTTCCGTGCCTACCTCGACAATGCCGCGG
CCGAGCAGGTCAGCGGCAACGAGAAGACCTCCAGGGCCGCTCTGGCGGGCATGCAGCACGCCGTGGACGCCAGCGGCCGC
GTGCTGCGCGACAACGTCTGGGGCCCGCAGGACGAGGACGCCACCCGCCGCGACTTCACCATCAACGCGATGTACTACGA
CCCGGCCACGCAGGTGGTGGTGGACTACCACAAGGGCATCCAGGACGCGCGCAAGAAGGTGATCCGCATGATCGGCGACC
CGGCCACGCGCTACCGCGAAGACCCGGTGCGCATCATCCGCGCCGTGCGCTTCGCGGCCAAGCTCGCCGGTGTCGGCTTC
ACGATCGAGCCCAAGACCGCGGCGCCGCTGGTGGAGTCGCAGGCGCTGCTGGCCGACGTGCCGCAGAGCCGCATGTTCGA
CGAGATGCTCAAGCTGCTGCAGACGGGCCATGCCATCGCCACGATCGAGCAGCTCAGGAAGCTGGGCCTCGCCACCGGTA
TCTACCCGCTGCTGGACGTGGTGGTGGAGCGGGCCGGCACGTCCTTCGTGAGCGCCGCGCTGGCCGACACCGACCGCCGC
GTGGGCGAGGGCAAGCCGGTCGCGCCGAGCTTCCTGCTCGCCTGCGTGCTCTGGCAGGACGTGAAGACGCAATGGGACCG
CCGCCTCGCGCAGCGCGAGCATCCGTTCCCGGCGCTGCAGGGCGCGATCGACGACGTGTTCGACCAGCGCATCGGCGATG
TGTCCGGCCGCGGCAAGCTGGCCGCCGACATGCGCGAGATCTGGGTCATGCAGCCGCGCTTCGAGAAGCGCGTGGGCACC
ACGCCGTTCAGCATGGTCACGCACCTGCGCTTCCGCGCGGGCTTCGACTTCCTGCGGCTGCGCGCCGATGTGGGCGAGAT
CGACGAGGCCCTGGCCGACTGGTGGCAGGAGTTCCAGCTGGCCGATGAAGCCCGCCGGGAGGACATGATCGACCAGGTGC
GCGAGGAGCAGAAGCAGCGCCAGCGCAAGAACCAGCCCGTGGTGCGCCGCGTGCCCAAGCCGGTGCCGCAGGAGGGCGCG
CCCGCCGCCGATGATGCGCCGCAGGCGCCCCCCGCCGGCGACGATGGCGCCGAAGGCAATGCCGGCGATTCTGGTGCCGT
GAAGAAGCGCCGTCGGCGCCGCCGCAAGCCTGCGGGCGGGGGCGATGGCGCGCCCCAGGGCGCACCCGACGCCTGA

Upstream 100 bases:

>100_bases
AAGTCGACCATCCCGTCGCCACCAACCCCGACCCCCGCCTGCGCGCACTGGCGCAGCAGCGCGGCTGGCGCATCCTGGAC
CTGTTTTCTACGCCAACACC

Downstream 100 bases:

>100_bases
TGCCCGGGGCGGCCATGGGCGTGTCCCGGGAGCCGGTCCTGGCCGGCATCGGTCTGGGCGCCAATCTCGGGGATGCCCGG
GCCGCGCTGGCCGGGGCCGT

Product: poly(A) polymerase

Products: NA

Alternate protein names: PAP [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MIKKFIDKLLGKAAPGTGRGKHRFGKREDVPASVHGIDPELVDRRATEVVRTLQQAGYEAYIVGGAVRDLLLGLKPKDFD
VATNATPEQVKGLFRRAFIIGKRFRIVHVVHGRGREHEVIEVSTFRAYLDNAAAEQVSGNEKTSRAALAGMQHAVDASGR
VLRDNVWGPQDEDATRRDFTINAMYYDPATQVVVDYHKGIQDARKKVIRMIGDPATRYREDPVRIIRAVRFAAKLAGVGF
TIEPKTAAPLVESQALLADVPQSRMFDEMLKLLQTGHAIATIEQLRKLGLATGIYPLLDVVVERAGTSFVSAALADTDRR
VGEGKPVAPSFLLACVLWQDVKTQWDRRLAQREHPFPALQGAIDDVFDQRIGDVSGRGKLAADMREIWVMQPRFEKRVGT
TPFSMVTHLRFRAGFDFLRLRADVGEIDEALADWWQEFQLADEARREDMIDQVREEQKQRQRKNQPVVRRVPKPVPQEGA
PAADDAPQAPPAGDDGAEGNAGDSGAVKKRRRRRRKPAGGGDGAPQGAPDA

Sequences:

>Translated_531_residues
MIKKFIDKLLGKAAPGTGRGKHRFGKREDVPASVHGIDPELVDRRATEVVRTLQQAGYEAYIVGGAVRDLLLGLKPKDFD
VATNATPEQVKGLFRRAFIIGKRFRIVHVVHGRGREHEVIEVSTFRAYLDNAAAEQVSGNEKTSRAALAGMQHAVDASGR
VLRDNVWGPQDEDATRRDFTINAMYYDPATQVVVDYHKGIQDARKKVIRMIGDPATRYREDPVRIIRAVRFAAKLAGVGF
TIEPKTAAPLVESQALLADVPQSRMFDEMLKLLQTGHAIATIEQLRKLGLATGIYPLLDVVVERAGTSFVSAALADTDRR
VGEGKPVAPSFLLACVLWQDVKTQWDRRLAQREHPFPALQGAIDDVFDQRIGDVSGRGKLAADMREIWVMQPRFEKRVGT
TPFSMVTHLRFRAGFDFLRLRADVGEIDEALADWWQEFQLADEARREDMIDQVREEQKQRQRKNQPVVRRVPKPVPQEGA
PAADDAPQAPPAGDDGAEGNAGDSGAVKKRRRRRRKPAGGGDGAPQGAPDA
>Mature_531_residues
MIKKFIDKLLGKAAPGTGRGKHRFGKREDVPASVHGIDPELVDRRATEVVRTLQQAGYEAYIVGGAVRDLLLGLKPKDFD
VATNATPEQVKGLFRRAFIIGKRFRIVHVVHGRGREHEVIEVSTFRAYLDNAAAEQVSGNEKTSRAALAGMQHAVDASGR
VLRDNVWGPQDEDATRRDFTINAMYYDPATQVVVDYHKGIQDARKKVIRMIGDPATRYREDPVRIIRAVRFAAKLAGVGF
TIEPKTAAPLVESQALLADVPQSRMFDEMLKLLQTGHAIATIEQLRKLGLATGIYPLLDVVVERAGTSFVSAALADTDRR
VGEGKPVAPSFLLACVLWQDVKTQWDRRLAQREHPFPALQGAIDDVFDQRIGDVSGRGKLAADMREIWVMQPRFEKRVGT
TPFSMVTHLRFRAGFDFLRLRADVGEIDEALADWWQEFQLADEARREDMIDQVREEQKQRQRKNQPVVRRVPKPVPQEGA
PAADDAPQAPPAGDDGAEGNAGDSGAVKKRRRRRRKPAGGGDGAPQGAPDA

Specific function: Polymerase that creates the 3' poly(A) tail found in some mRNA's [H]

COG id: COG0617

COG function: function code J; tRNA nucleotidyltransferase/poly(A) polymerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family [H]

Homologues:

Organism=Homo sapiens, GI155030240, Length=254, Percent_Identity=30.3149606299213, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI87081691, Length=435, Percent_Identity=40, Blast_Score=301, Evalue=7e-83,
Organism=Escherichia coli, GI1789436, Length=244, Percent_Identity=29.0983606557377, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995920, Length=288, Percent_Identity=29.5138888888889, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321016, Length=249, Percent_Identity=24.8995983935743, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002646
- InterPro:   IPR010206 [H]

Pfam domain/function: PF01743 PolyA_pol [H]

EC number: =2.7.7.19 [H]

Molecular weight: Translated: 58828; Mature: 58828

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKFIDKLLGKAAPGTGRGKHRFGKREDVPASVHGIDPELVDRRATEVVRTLQQAGYEA
CHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCEE
YIVGGAVRDLLLGLKPKDFDVATNATPEQVKGLFRRAFIIGKRFRIVHVVHGRGREHEVI
EEECHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEE
EVSTFRAYLDNAAAEQVSGNEKTSRAALAGMQHAVDASGRVLRDNVWGPQDEDATRRDFT
EHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCEE
INAMYYDPATQVVVDYHKGIQDARKKVIRMIGDPATRYREDPVRIIRAVRFAAKLAGVGF
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCE
TIEPKTAAPLVESQALLADVPQSRMFDEMLKLLQTGHAIATIEQLRKLGLATGIYPLLDV
EECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VVERAGTSFVSAALADTDRRVGEGKPVAPSFLLACVLWQDVKTQWDRRLAQREHPFPALQ
HHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GAIDDVFDQRIGDVSGRGKLAADMREIWVMQPRFEKRVGTTPFSMVTHLRFRAGFDFLRL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCHHHHHH
RADVGEIDEALADWWQEFQLADEARREDMIDQVREEQKQRQRKNQPVVRRVPKPVPQEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
PAADDAPQAPPAGDDGAEGNAGDSGAVKKRRRRRRKPAGGGDGAPQGAPDA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIKKFIDKLLGKAAPGTGRGKHRFGKREDVPASVHGIDPELVDRRATEVVRTLQQAGYEA
CHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCEE
YIVGGAVRDLLLGLKPKDFDVATNATPEQVKGLFRRAFIIGKRFRIVHVVHGRGREHEVI
EEECHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEE
EVSTFRAYLDNAAAEQVSGNEKTSRAALAGMQHAVDASGRVLRDNVWGPQDEDATRRDFT
EHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCEE
INAMYYDPATQVVVDYHKGIQDARKKVIRMIGDPATRYREDPVRIIRAVRFAAKLAGVGF
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCE
TIEPKTAAPLVESQALLADVPQSRMFDEMLKLLQTGHAIATIEQLRKLGLATGIYPLLDV
EECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VVERAGTSFVSAALADTDRRVGEGKPVAPSFLLACVLWQDVKTQWDRRLAQREHPFPALQ
HHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GAIDDVFDQRIGDVSGRGKLAADMREIWVMQPRFEKRVGTTPFSMVTHLRFRAGFDFLRL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCHHHHHH
RADVGEIDEALADWWQEFQLADEARREDMIDQVREEQKQRQRKNQPVVRRVPKPVPQEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
PAADDAPQAPPAGDDGAEGNAGDSGAVKKRRRRRRKPAGGGDGAPQGAPDA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]