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The map label for this gene is dinB [H]

Identifier: 120610644

GI number: 120610644

Start: 2134404

End: 2135681

Strand: Direct

Name: dinB [H]

Synonym: Aave_1964

Alternate gene names: 120610644

Gene position: 2134404-2135681 (Clockwise)

Preceding gene: 120610643

Following gene: 120610651

Centisome position: 39.87

GC content: 70.97

Gene sequence:

>1278_bases
ATGCGTTCCGTGAGCGCATCCCCTGACACGTCCGCGCAGCCGCAGGCCGCGGCCCTTCCCGCCGGCGCGGCGGCGGCGTC
CCTGCCGCGCCGCATCGCTCACCTGGACATGGATGCCTTCTACGCCTCGGTCGAGCTGCTGCGCTATCCGCAGCTCAAGG
GCCTGCCGGCCGTCATCGGCGGCGGCCGCCGGAGCGAGGACGAGGCACTCGCCCGGGCCTATGCCGGCCGCGAGTCCGAG
ATCCCGGTGGAGGCTTTTCCGCTGCTGCGCGACTACGTGGGCCGGGGCGTGATCACCACCGCCACCTACCCGGCCCGGCA
GTTCGGCGTGGGCTCGGCCATGGGCCTGATGAAGGCGGCGCGGCTGTGCCCGCAGGCCATCCTGCTGCCGGTGGATTTCG
CGTCCTACCGGCGCTTCTCGCGGCAGTTCAAGGACGTGATCCTCTCCATCGCCCCCGTCATGGAAGACCGCGGCGTGGAC
GAGGTGTATATCGACTTCACCGCGGTGCCCGGGGGCCAGCGCGAGGGCGGGCGGGTGCTCGCGCGGCTCATCCAGAAAAG
CATCTTCGAGGTCACGGGCCTGACCTGCTCGATCGGCGTCGCGCCCAACAAGCTCATCGCCAAGATGGCGAGCGAATTCA
ACAAGCCCAACGGCATCTCGATCGTGCACGAGGGCGACCTGCAGGCGGCGATCTGGCCGCTGGCCTGCCGCAAGATCAAC
GGTATCGGCCCCAAGGCCGACGCCAAACTGCAGTCCTACGGCATCCACACCATCGGCGACCTCGCGGCGCGCCCGCGCGA
CTGGCTGGTGCGCACCTTCGGCAAGGCGTACGGCGCCTGGCTGCACGAGGCCGCCTGGGGGCGCGACGACCGGGCCGTGG
TGACCGAGAGCGAGCCCGTCTCCATGAGCCGCGAGACCACCTTCGACCGCGACCTGCACGCCGTGCGCGACCGCGCGGAA
CTCGGCCGCATCTTCACCGACCTGTGCGAGCGCGTGGCCGAAGACCTGCGCCGCAAGGGCTACGTGGGCAAGACGATCGG
CATCAAGCTGCGCTACGACGACTTCAGGATCGCCACGCGCGACCAGACCATCGCGGCCTACACGCGCGACGCCGCCGCGA
TCCGCCGCACGGCGGGCGAATGCCTCAAGCGCGTGCCGCTGGACAAGCGCCTGCGGCTGCTGGGGGTGCGCGTGGGCAAT
CTGCTGACGGATGAGGAAGCACGCGAGGCCGAGGCGGCGGCCCGCGTGCCGGAGACGCGGCGGCTCTTCGACGACTGA

Upstream 100 bases:

>100_bases
CGCCCATGCACCGCGACATCATCACCGTCCGCTGAACGAATGCCCGGGCCGCGGCGGGGCACGCCGCGGTGCGCTGCAGG
CGCCGGGCGGGCGCGGCACA

Downstream 100 bases:

>100_bases
CGCTACTTCGTAGCCCGCCGGGCTTGCCGCAGTCCGCTGCCTCTCGGCTTCCTCCAGGCGCTTCCTGGCCTCTGCCAGTT
CCATGTCACCGAGAAGCTTG

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MRSVSASPDTSAQPQAAALPAGAAAASLPRRIAHLDMDAFYASVELLRYPQLKGLPAVIGGGRRSEDEALARAYAGRESE
IPVEAFPLLRDYVGRGVITTATYPARQFGVGSAMGLMKAARLCPQAILLPVDFASYRRFSRQFKDVILSIAPVMEDRGVD
EVYIDFTAVPGGQREGGRVLARLIQKSIFEVTGLTCSIGVAPNKLIAKMASEFNKPNGISIVHEGDLQAAIWPLACRKIN
GIGPKADAKLQSYGIHTIGDLAARPRDWLVRTFGKAYGAWLHEAAWGRDDRAVVTESEPVSMSRETTFDRDLHAVRDRAE
LGRIFTDLCERVAEDLRRKGYVGKTIGIKLRYDDFRIATRDQTIAAYTRDAAAIRRTAGECLKRVPLDKRLRLLGVRVGN
LLTDEEAREAEAAARVPETRRLFDD

Sequences:

>Translated_425_residues
MRSVSASPDTSAQPQAAALPAGAAAASLPRRIAHLDMDAFYASVELLRYPQLKGLPAVIGGGRRSEDEALARAYAGRESE
IPVEAFPLLRDYVGRGVITTATYPARQFGVGSAMGLMKAARLCPQAILLPVDFASYRRFSRQFKDVILSIAPVMEDRGVD
EVYIDFTAVPGGQREGGRVLARLIQKSIFEVTGLTCSIGVAPNKLIAKMASEFNKPNGISIVHEGDLQAAIWPLACRKIN
GIGPKADAKLQSYGIHTIGDLAARPRDWLVRTFGKAYGAWLHEAAWGRDDRAVVTESEPVSMSRETTFDRDLHAVRDRAE
LGRIFTDLCERVAEDLRRKGYVGKTIGIKLRYDDFRIATRDQTIAAYTRDAAAIRRTAGECLKRVPLDKRLRLLGVRVGN
LLTDEEAREAEAAARVPETRRLFDD
>Mature_425_residues
MRSVSASPDTSAQPQAAALPAGAAAASLPRRIAHLDMDAFYASVELLRYPQLKGLPAVIGGGRRSEDEALARAYAGRESE
IPVEAFPLLRDYVGRGVITTATYPARQFGVGSAMGLMKAARLCPQAILLPVDFASYRRFSRQFKDVILSIAPVMEDRGVD
EVYIDFTAVPGGQREGGRVLARLIQKSIFEVTGLTCSIGVAPNKLIAKMASEFNKPNGISIVHEGDLQAAIWPLACRKIN
GIGPKADAKLQSYGIHTIGDLAARPRDWLVRTFGKAYGAWLHEAAWGRDDRAVVTESEPVSMSRETTFDRDLHAVRDRAE
LGRIFTDLCERVAEDLRRKGYVGKTIGIKLRYDDFRIATRDQTIAAYTRDAAAIRRTAGECLKRVPLDKRLRLLGVRVGN
LLTDEEAREAEAAARVPETRRLFDD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=26.3157894736842, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI154350220, Length=368, Percent_Identity=25.5434782608696, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=26.3929618768328, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI7705344, Length=231, Percent_Identity=30.3030303030303, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI5729982, Length=429, Percent_Identity=22.8438228438228, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1786425, Length=335, Percent_Identity=33.4328358208955, Blast_Score=168, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI193205700, Length=451, Percent_Identity=25.4988913525499, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI193205702, Length=267, Percent_Identity=31.4606741573034, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17537959, Length=246, Percent_Identity=23.5772357723577, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324921, Length=278, Percent_Identity=25.1798561151079, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19923006, Length=353, Percent_Identity=26.3456090651558, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 46680; Mature: 46680

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSVSASPDTSAQPQAAALPAGAAAASLPRRIAHLDMDAFYASVELLRYPQLKGLPAVIG
CCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCC
GGRRSEDEALARAYAGRESEIPVEAFPLLRDYVGRGVITTATYPARQFGVGSAMGLMKAA
CCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHCCHHHHHHHHHH
RLCPQAILLPVDFASYRRFSRQFKDVILSIAPVMEDRGVDEVYIDFTAVPGGQREGGRVL
HHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHH
ARLIQKSIFEVTGLTCSIGVAPNKLIAKMASEFNKPNGISIVHEGDLQAAIWPLACRKIN
HHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHC
GIGPKADAKLQSYGIHTIGDLAARPRDWLVRTFGKAYGAWLHEAAWGRDDRAVVTESEPV
CCCCCCCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
SMSRETTFDRDLHAVRDRAELGRIFTDLCERVAEDLRRKGYVGKTIGIKLRYDDFRIATR
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEC
DQTIAAYTRDAAAIRRTAGECLKRVPLDKRLRLLGVRVGNLLTDEEAREAEAAARVPETR
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHH
RLFDD
HHCCC
>Mature Secondary Structure
MRSVSASPDTSAQPQAAALPAGAAAASLPRRIAHLDMDAFYASVELLRYPQLKGLPAVIG
CCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCC
GGRRSEDEALARAYAGRESEIPVEAFPLLRDYVGRGVITTATYPARQFGVGSAMGLMKAA
CCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHCCHHHHHHHHHH
RLCPQAILLPVDFASYRRFSRQFKDVILSIAPVMEDRGVDEVYIDFTAVPGGQREGGRVL
HHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHH
ARLIQKSIFEVTGLTCSIGVAPNKLIAKMASEFNKPNGISIVHEGDLQAAIWPLACRKIN
HHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHC
GIGPKADAKLQSYGIHTIGDLAARPRDWLVRTFGKAYGAWLHEAAWGRDDRAVVTESEPV
CCCCCCCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
SMSRETTFDRDLHAVRDRAELGRIFTDLCERVAEDLRRKGYVGKTIGIKLRYDDFRIATR
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEC
DQTIAAYTRDAAAIRRTAGECLKRVPLDKRLRLLGVRVGNLLTDEEAREAEAAARVPETR
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHH
RLFDD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]