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The map label for this gene is ybaL [H]

Identifier: 120610477

GI number: 120610477

Start: 1945563

End: 1947320

Strand: Direct

Name: ybaL [H]

Synonym: Aave_1796

Alternate gene names: 120610477

Gene position: 1945563-1947320 (Clockwise)

Preceding gene: 120610476

Following gene: 120610481

Centisome position: 36.35

GC content: 72.47

Gene sequence:

>1758_bases
ATGCCCCATAGCGTCGCCCTCATCCATACGATCGCCGTCGGCCTCGGCCTGGCGCTGCTGCTGGGCTTCCTGGCGACGCG
GGTGCGCCTGCCCGCGCTGGTGGGCTACCTGCTGGCGGGCGTGGCGATCGGGCCCTACACGCCCGGTTTCGTGGCCGACG
GCGCCATGGCCAGCCAGCTGGCCGAGATCGGCGTCATGCTGCTGATGTTCGGCGTGGGCCTGCACTTCTCACTGGGCGAC
CTGCTCGCCGTGCGCAGGATCGCCCTGCCGGGCGCCATCGTGCAGATGGCCGTGGCCACGCTGCTGGGCGTGGGCCTGGC
CAGCTGGTGGGGCTGGGGCCTGGGCGGCGCGCTGGTCTTCGGCCTGGCCCTGTCGGTGGCCAGCACGGTGGTGCTGCTGC
GGGCGCTGGAAACGCTGGGAATTCTCGACTCCTACACGGGCCGCATCGCGGTCGGGTGGCTGGTGGTGGAGGACCTCGCC
ATGGTGCTGGTGCTGGTGCTGCTGCCGCCCCTGGCGGGGTGGCTCGGCGGCACGCCGGAGGGTCCGGCCGGTGCCGCGGC
CCATCCTCCGCTCTGGAAGACCGTGGGCTGGACGCTGGCGCAGGTGGGCGGCTTCGTGGCCGTGATGCTGCTCGTGGGGC
GGCGGCTCTTTCCCTGGCTGCTGTGGCAGGTGGCGCGCACGGGCTCGCGCGAGCTGTTCACGCTGTGCGTGGTGGCGGCG
GCCGTGGGCATCGCTTTCGGCTCGGCCGCGCTGTTCGGGGTGTCGTTCGCGCTCGGCGCGTTCTTCGCGGGCATGGTGAT
GCGCGAGTCGGAGTTCGCCCACCGGGCCGCGCAGGAGTCGCTGCCGCTGCGCGATGCCTTTGCCGTGCTGTTCTTCGTCT
CCGTGGGCATGCTGTTCGATCCGCGCGTGCTGCTCGAGCGCCCCCTGCAGGTGCTCGCCGTGGTGGCGATCATCATCTTC
GGCAAGACCTTCGCGGCGGCCGCGCTGGTGCTGGCTTTCCGCTACCCGCTCAACACGGCGCTCACCGTGTCGGCCAGCCT
GGCGCAGATCGGCGAGTTCTCGTTCATCCTCGTGGGCCTGGGCGCATCGCTCGGTCTGCTGCCTCCGGAAGGCGCGAGCC
TGGTGCTGGCGGGCGCGCTGTTTTCCATCGCCCTCAACCCCATCCTGTTCCGCGCCATCGCGCCGCTGCAGGACTGGCTG
CGTGCGCGCTCCGCCTGGGCGCGGCAACTGGAACTGCGCGACGATCCGCTGGCGGAACTGCCTGAGACCACGCACCAGCG
CTACCTGGCCCGGCAGGTGGTGCTGGTCGGCTACGGCCGGGTGGGGCGCCGCATCGCCGCCGCGCTGGCCGCGCGCGACA
TTCCCTTCGTGGTGGCCGAGCAGAACCGGGAACTGGTCGAGCGGCTGCGCGGCCAGGGCATGGCCGCCGTCGCCGGCGAC
GCCGTGGACCCGGCCGTGCTGATCCAGGCGCACATCGCGCGGGCCCACATGCTGGTGATCGCCACGCCGGACACGCTGGA
CGTGCGGCAGATCGTCGCCACCGCGCGCACGCTCAATCCCGGCATCGAGACCGTGGTGCGCTCCCACAACGAGGAGGAGG
CGCACCTGCTCGAAAGCGAAGGCGTGGGCAAGGTCTTCCTGGGCGAGGAGGCCCTGGCCGTGGCCATGACCACCCACGTG
GTGGACGTGGCGGCCGGCCAGGAGCGGCCGGGCACCACCGTGCCGGGCGCGCTGGACGAGCGGCACGTGTCCGCCTGA

Upstream 100 bases:

>100_bases
ATCGCCGTCCTGCTGCTTTGCGGTTATAACGGAACGCAGCGAGATCGCTTCCTCCGCCCCTCCCGCGCTCTGAGCGCTGC
CAAAGCCCATCCTTTGACAC

Downstream 100 bases:

>100_bases
GCCGCCGGCGCGTTCCGGGTGGCGCCGGCGGGCCGGATCAGTCCGGTTCCTCGAACACCAGCGTCGGCGTGGTCATCACC
CGGGCCATGTCGCCCAGCGA

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MPHSVALIHTIAVGLGLALLLGFLATRVRLPALVGYLLAGVAIGPYTPGFVADGAMASQLAEIGVMLLMFGVGLHFSLGD
LLAVRRIALPGAIVQMAVATLLGVGLASWWGWGLGGALVFGLALSVASTVVLLRALETLGILDSYTGRIAVGWLVVEDLA
MVLVLVLLPPLAGWLGGTPEGPAGAAAHPPLWKTVGWTLAQVGGFVAVMLLVGRRLFPWLLWQVARTGSRELFTLCVVAA
AVGIAFGSAALFGVSFALGAFFAGMVMRESEFAHRAAQESLPLRDAFAVLFFVSVGMLFDPRVLLERPLQVLAVVAIIIF
GKTFAAAALVLAFRYPLNTALTVSASLAQIGEFSFILVGLGASLGLLPPEGASLVLAGALFSIALNPILFRAIAPLQDWL
RARSAWARQLELRDDPLAELPETTHQRYLARQVVLVGYGRVGRRIAAALAARDIPFVVAEQNRELVERLRGQGMAAVAGD
AVDPAVLIQAHIARAHMLVIATPDTLDVRQIVATARTLNPGIETVVRSHNEEEAHLLESEGVGKVFLGEEALAVAMTTHV
VDVAAGQERPGTTVPGALDERHVSA

Sequences:

>Translated_585_residues
MPHSVALIHTIAVGLGLALLLGFLATRVRLPALVGYLLAGVAIGPYTPGFVADGAMASQLAEIGVMLLMFGVGLHFSLGD
LLAVRRIALPGAIVQMAVATLLGVGLASWWGWGLGGALVFGLALSVASTVVLLRALETLGILDSYTGRIAVGWLVVEDLA
MVLVLVLLPPLAGWLGGTPEGPAGAAAHPPLWKTVGWTLAQVGGFVAVMLLVGRRLFPWLLWQVARTGSRELFTLCVVAA
AVGIAFGSAALFGVSFALGAFFAGMVMRESEFAHRAAQESLPLRDAFAVLFFVSVGMLFDPRVLLERPLQVLAVVAIIIF
GKTFAAAALVLAFRYPLNTALTVSASLAQIGEFSFILVGLGASLGLLPPEGASLVLAGALFSIALNPILFRAIAPLQDWL
RARSAWARQLELRDDPLAELPETTHQRYLARQVVLVGYGRVGRRIAAALAARDIPFVVAEQNRELVERLRGQGMAAVAGD
AVDPAVLIQAHIARAHMLVIATPDTLDVRQIVATARTLNPGIETVVRSHNEEEAHLLESEGVGKVFLGEEALAVAMTTHV
VDVAAGQERPGTTVPGALDERHVSA
>Mature_584_residues
PHSVALIHTIAVGLGLALLLGFLATRVRLPALVGYLLAGVAIGPYTPGFVADGAMASQLAEIGVMLLMFGVGLHFSLGDL
LAVRRIALPGAIVQMAVATLLGVGLASWWGWGLGGALVFGLALSVASTVVLLRALETLGILDSYTGRIAVGWLVVEDLAM
VLVLVLLPPLAGWLGGTPEGPAGAAAHPPLWKTVGWTLAQVGGFVAVMLLVGRRLFPWLLWQVARTGSRELFTLCVVAAA
VGIAFGSAALFGVSFALGAFFAGMVMRESEFAHRAAQESLPLRDAFAVLFFVSVGMLFDPRVLLERPLQVLAVVAIIIFG
KTFAAAALVLAFRYPLNTALTVSASLAQIGEFSFILVGLGASLGLLPPEGASLVLAGALFSIALNPILFRAIAPLQDWLR
ARSAWARQLELRDDPLAELPETTHQRYLARQVVLVGYGRVGRRIAAALAARDIPFVVAEQNRELVERLRGQGMAAVAGDA
VDPAVLIQAHIARAHMLVIATPDTLDVRQIVATARTLNPGIETVVRSHNEEEAHLLESEGVGKVFLGEEALAVAMTTHVV
DVAAGQERPGTTVPGALDERHVSA

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=414, Percent_Identity=28.5024154589372, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1786685, Length=557, Percent_Identity=53.5008976660682, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1789749, Length=522, Percent_Identity=29.6934865900383, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI1786232, Length=541, Percent_Identity=28.8354898336414, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 61567; Mature: 61436

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PHSVALIHTIAVGLGLALLLGFLATRVRLPALVGYLLAGVAIGPYTPGFVADGAMASQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHH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CCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]