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The map label for this gene is pgsA [H]

Identifier: 120610348

GI number: 120610348

Start: 1827333

End: 1827902

Strand: Direct

Name: pgsA [H]

Synonym: Aave_1665

Alternate gene names: 120610348

Gene position: 1827333-1827902 (Clockwise)

Preceding gene: 120610347

Following gene: 120610349

Centisome position: 34.14

GC content: 65.79

Gene sequence:

>570_bases
ATGTTCCTGACCATTCCCACCATCATGACCTGGACGCGCATCGTCGCGATACCCTTGATCGTGGGCGTGTTCTACGCGCC
GCTGGAGCCGGCCACGCGCAACCTCATCGCCACGGTGATGTTCGTGGTGTTCGCCGCCACCGACTGGCTCGACGGCTACC
TGGCGCGCAAGCTGAACCAGACCTCCTCCTTCGGCGCCTTCCTCGATCCGGTCGCCGACAAATTCCTCGTCTGCGCGTCG
CTGCTCGTGCTGGTGCACCTGCAGCGCGCCGACGTGTTCGTTGCGCTCATCATCATCGGCCGGGAGATCGCGATCTCCGC
CCTGCGCGAATGGATGGCGCAGATCGGGGCCTCGCGCAGCGTGGCGGTGCACATGCTGGGCAAGGTGAAGACCACGGTGC
AGATGGTCGCCATCCCGTTCCTGCTCTACGACGGGCGCGTCGCCGGCACCATCGACACGGGCGTCTGGGGCACGTGGCTG
ATCTGGCTGGCCGCGGTGCTCACCGTGTGGTCCATGGTCTATTACCTGCAGAAGGCTTTGCCGGAGATCCGCGCGCGCGT
CAAGCGGTGA

Upstream 100 bases:

>100_bases
CTGGCCACGGTGGACGGCATCTCGCTGGAGCTCGCGCAGGAGATATACCGGGCGCTGCGCTGAGCCGGCGGCGGCCATGG
TGGCATGACACAATCGACCC

Downstream 100 bases:

>100_bases
GCGGCGCGGCCCTGCCGCATGTCAATGGGTGCTTGCGATAGCGCGCGCGACGCCCGTTGCGCAAACCCCGCGCATCGCCT
GGCGCCTCTGGAATTGCCGC

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MFLTIPTIMTWTRIVAIPLIVGVFYAPLEPATRNLIATVMFVVFAATDWLDGYLARKLNQTSSFGAFLDPVADKFLVCAS
LLVLVHLQRADVFVALIIIGREIAISALREWMAQIGASRSVAVHMLGKVKTTVQMVAIPFLLYDGRVAGTIDTGVWGTWL
IWLAAVLTVWSMVYYLQKALPEIRARVKR

Sequences:

>Translated_189_residues
MFLTIPTIMTWTRIVAIPLIVGVFYAPLEPATRNLIATVMFVVFAATDWLDGYLARKLNQTSSFGAFLDPVADKFLVCAS
LLVLVHLQRADVFVALIIIGREIAISALREWMAQIGASRSVAVHMLGKVKTTVQMVAIPFLLYDGRVAGTIDTGVWGTWL
IWLAAVLTVWSMVYYLQKALPEIRARVKR
>Mature_189_residues
MFLTIPTIMTWTRIVAIPLIVGVFYAPLEPATRNLIATVMFVVFAATDWLDGYLARKLNQTSSFGAFLDPVADKFLVCAS
LLVLVHLQRADVFVALIIIGREIAISALREWMAQIGASRSVAVHMLGKVKTTVQMVAIPFLLYDGRVAGTIDTGVWGTWL
IWLAAVLTVWSMVYYLQKALPEIRARVKR

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=185, Percent_Identity=48.1081081081081, Blast_Score=139, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21040; Mature: 21040

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLTIPTIMTWTRIVAIPLIVGVFYAPLEPATRNLIATVMFVVFAATDWLDGYLARKLNQ
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSSFGAFLDPVADKFLVCASLLVLVHLQRADVFVALIIIGREIAISALREWMAQIGASRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VAVHMLGKVKTTVQMVAIPFLLYDGRVAGTIDTGVWGTWLIWLAAVLTVWSMVYYLQKAL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PEIRARVKR
HHHHHHHCC
>Mature Secondary Structure
MFLTIPTIMTWTRIVAIPLIVGVFYAPLEPATRNLIATVMFVVFAATDWLDGYLARKLNQ
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSSFGAFLDPVADKFLVCASLLVLVHLQRADVFVALIIIGREIAISALREWMAQIGASRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VAVHMLGKVKTTVQMVAIPFLLYDGRVAGTIDTGVWGTWLIWLAAVLTVWSMVYYLQKAL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PEIRARVKR
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]