Click here to switch to the map view.

The map label for this gene is gsiD [H]

Identifier: 120610343

GI number: 120610343

Start: 1821285

End: 1822220

Strand: Direct

Name: gsiD [H]

Synonym: Aave_1660

Alternate gene names: 120610343

Gene position: 1821285-1822220 (Clockwise)

Preceding gene: 120610342

Following gene: 120610344

Centisome position: 34.03

GC content: 69.12

Gene sequence:

>936_bases
ATGACCACGCCCTCCATTCCCACCCCGCCCGACGCCGCCCAGATCGCCGCGGCCTCGGTGGCCCCCGCCGCCGGCGCCTC
CAAGGTGCGCACCCCCTGGCGCGAGTTCTGGCGCAAGTTCAAGAAGCAGCACGTCGCGGTGGCCGCGCTGGTGTTCGTCG
TGCTGCTCGTCGCCGTGGCCGTGCTGGCTCCGGCCATCGTGCCCTTCGACGCGGAGAACTTCTTCGACTACGACCGGATC
AACGACGGCCCCTCGGCCATGCACTGGTTCGGCGTCGATCCGCTGGGCCGCGACATCTTCAGCCGCATCCTGATGGGCGC
GCGCATCTCGCTGGCCGCGGGCTTCCTCTCGGTGGCGATCGGCTGCCTGATCGGCACCACGCTGGGCCTGCTGGCCGGCT
ACTACGAAGGCTGGTGGGATCGCATCGTGATGCGCATCTCCGACGTGCTGTTCGCCTTCCCCGGCATCCTGCTGGCGCTG
GGCGTGGTCGCCATCCTGGGCAGCAGCATGACCAACGTGGTGGTGGCCGTGGCGGTGTTCAGCGTGCCGGCCTTCGCGCG
GCTGGTGCGCGGCAACACGCTGGTGCTCAAGCAGATGACCTACATCGAGTCCGCGCGCAGCATCGGCGCCTCGGACTGGA
CCATCATCGTGCGGCACATCCTGCCGGGCACCATCTCCTCCATCGTCGTGTACTTCACGATGCGCGTGGGCACCTCCATC
ATCACGGCCGCCAGCCTGTCCTTCCTCGGCATGGGCGCGCAGCCGCCGACGCCGGAGTGGGGCGCCATGCTCAACGAAGC
GCGTGCCGACATGGTGAACGCGCCGCACGTCGCGCTGTTCCCCAGCCTCGCCATCTTCCTGACGGTGCTGGCCTTCAACC
TGCTGGGCGACGGCCTGCGCGACGCGCTGGACCCCAAGATCGACCGGCAGACATGA

Upstream 100 bases:

>100_bases
ATCAACCTGGTGGTGGACATGCTCTACGGCTTCATCAACCCGACCATCCGCTACAAGTGAAGCGCACGGACCGGACCCTC
TCCACCGACGAAGACACGGT

Downstream 100 bases:

>100_bases
GCGCGCGCGACCCCGCCGCCACGGCGCCGCCGCGCATCGGCCTGCTGGACGCGGGCCCCCTGGATGCGATCACCGACGTG
GCCGGCGTCACCGTCGGCCA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTTPSIPTPPDAAQIAAASVAPAAGASKVRTPWREFWRKFKKQHVAVAALVFVVLLVAVAVLAPAIVPFDAENFFDYDRI
NDGPSAMHWFGVDPLGRDIFSRILMGARISLAAGFLSVAIGCLIGTTLGLLAGYYEGWWDRIVMRISDVLFAFPGILLAL
GVVAILGSSMTNVVVAVAVFSVPAFARLVRGNTLVLKQMTYIESARSIGASDWTIIVRHILPGTISSIVVYFTMRVGTSI
ITAASLSFLGMGAQPPTPEWGAMLNEARADMVNAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPKIDRQT

Sequences:

>Translated_311_residues
MTTPSIPTPPDAAQIAAASVAPAAGASKVRTPWREFWRKFKKQHVAVAALVFVVLLVAVAVLAPAIVPFDAENFFDYDRI
NDGPSAMHWFGVDPLGRDIFSRILMGARISLAAGFLSVAIGCLIGTTLGLLAGYYEGWWDRIVMRISDVLFAFPGILLAL
GVVAILGSSMTNVVVAVAVFSVPAFARLVRGNTLVLKQMTYIESARSIGASDWTIIVRHILPGTISSIVVYFTMRVGTSI
ITAASLSFLGMGAQPPTPEWGAMLNEARADMVNAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPKIDRQT
>Mature_310_residues
TTPSIPTPPDAAQIAAASVAPAAGASKVRTPWREFWRKFKKQHVAVAALVFVVLLVAVAVLAPAIVPFDAENFFDYDRIN
DGPSAMHWFGVDPLGRDIFSRILMGARISLAAGFLSVAIGCLIGTTLGLLAGYYEGWWDRIVMRISDVLFAFPGILLALG
VVAILGSSMTNVVVAVAVFSVPAFARLVRGNTLVLKQMTYIESARSIGASDWTIIVRHILPGTISSIVVYFTMRVGTSII
TAASLSFLGMGAQPPTPEWGAMLNEARADMVNAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPKIDRQT

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=293, Percent_Identity=74.7440273037543, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1787760, Length=267, Percent_Identity=40.4494382022472, Blast_Score=213, Evalue=9e-57,
Organism=Escherichia coli, GI1789964, Length=284, Percent_Identity=43.3098591549296, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1787498, Length=282, Percent_Identity=37.2340425531915, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1789889, Length=224, Percent_Identity=38.3928571428571, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787549, Length=284, Percent_Identity=32.3943661971831, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788505, Length=225, Percent_Identity=31.1111111111111, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33299; Mature: 33167

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCCC
>Mature Secondary Structure 
TTPSIPTPPDAAQIAAASVAPAAGASKVRTPWREFWRKFKKQHVAVAALVFVVLLVAVA
CCCCCCCCCCHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAPAIVPFDAENFFDYDRINDGPSAMHWFGVDPLGRDIFSRILMGARISLAAGFLSVAI
HHHHHHCCCCCHHCCCHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GCLIGTTLGLLAGYYEGWWDRIVMRISDVLFAFPGILLALGVVAILGSSMTNVVVAVAVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SVPAFARLVRGNTLVLKQMTYIESARSIGASDWTIIVRHILPGTISSIVVYFTMRVGTSI
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ITAASLSFLGMGAQPPTPEWGAMLNEARADMVNAPHVALFPSLAIFLTVLAFNLLGDGLR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DALDPKIDRQT
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA