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The map label for this gene is gsiC [H]

Identifier: 120610342

GI number: 120610342

Start: 1820324

End: 1821244

Strand: Direct

Name: gsiC [H]

Synonym: Aave_1659

Alternate gene names: 120610342

Gene position: 1820324-1821244 (Clockwise)

Preceding gene: 120610341

Following gene: 120610343

Centisome position: 34.01

GC content: 66.88

Gene sequence:

>921_bases
ATGCTGAACTATTTCCTCAAACGACTGCTGGGGCTGCTTCCCGCGCTGCTGATCGTGGCGGTACTGGTGTTCCTGTTCGT
CCACATGCTGCCGGGCGATCCCGCCCGCCTGGCCGCGGGCGTGGACGCCGACGAGGCCACCGTGCAGGTCGTTCGCCAGG
AACTGGGCCTGGACAGGCCCCTGCCCGAGCAGTTCGTGCACTTCTTCTCGCGCATGGTGCAAGGGGATTTCGGCACGTCC
ATCCGCACCCGCCGCCCGGTGGCCGCCGAGATCGGCGAGCGCTTCATGCCCACGCTGCTGCTCACCATCGCCGCCATGGC
GTGGTCCGTGGTGATCGGCATGGGCATCGGCATCCTGTCGGCCGTGTACCGCAACCGCTGGCCCGACCGGCTCGGCATGA
CGCTCGCGGTCTCCGGCATTTCCTTTCCCGCGTTCGCGCTCGGCATGACGCTGATGCAGGTCTTCTCGGTGGAGCTCGGC
TGGCTGCCCACCGTGGGCGCCGACAGCTGGAAGCACTACATCCTGCCCTCCATCACGCTGGGTGCCGCGGTGGCCGCCGT
GATGGCCCGCTTCACGCGCGCCTCCTTCGTCGAGGTGGTGCAGGAGGACTTCGTGCGCACCGCGCGCGCCAAGGGCCTCA
ACGAGCGCACCGTGGTGCTCAAGCACTGCCTGCGCAACGCGCTCATCCCGGTCGTCACCATGATGGGCCTGCAGTTCGGC
TTCCTGCTGGGCGGATCCATCGTCGTGGAGGCGGTCTTCAACTGGCCCGGCCTCGGCCGCCTGCTGGTGGACGCCGTGAC
CATGCGCGACTACCCCGTCATCCAGACGCTGGTGCTGCTTTTCTCGCTGGAGTTCATCCTCATCAACCTGGTGGTGGACA
TGCTCTACGGCTTCATCAACCCGACCATCCGCTACAAGTGA

Upstream 100 bases:

>100_bases
GTAAGCCCGGTGCACGGCCCCCGCAGACAGCGGGGGCCCTTTTTCCCGTTTCCCGCTCCGCTCCCGTTTTCCCCCTCGCT
GCACACCGCGGCGCCGCATC

Downstream 100 bases:

>100_bases
AGCGCACGGACCGGACCCTCTCCACCGACGAAGACACGGTATGACCACGCCCTCCATTCCCACCCCGCCCGACGCCGCCC
AGATCGCCGCGGCCTCGGTG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLNYFLKRLLGLLPALLIVAVLVFLFVHMLPGDPARLAAGVDADEATVQVVRQELGLDRPLPEQFVHFFSRMVQGDFGTS
IRTRRPVAAEIGERFMPTLLLTIAAMAWSVVIGMGIGILSAVYRNRWPDRLGMTLAVSGISFPAFALGMTLMQVFSVELG
WLPTVGADSWKHYILPSITLGAAVAAVMARFTRASFVEVVQEDFVRTARAKGLNERTVVLKHCLRNALIPVVTMMGLQFG
FLLGGSIVVEAVFNWPGLGRLLVDAVTMRDYPVIQTLVLLFSLEFILINLVVDMLYGFINPTIRYK

Sequences:

>Translated_306_residues
MLNYFLKRLLGLLPALLIVAVLVFLFVHMLPGDPARLAAGVDADEATVQVVRQELGLDRPLPEQFVHFFSRMVQGDFGTS
IRTRRPVAAEIGERFMPTLLLTIAAMAWSVVIGMGIGILSAVYRNRWPDRLGMTLAVSGISFPAFALGMTLMQVFSVELG
WLPTVGADSWKHYILPSITLGAAVAAVMARFTRASFVEVVQEDFVRTARAKGLNERTVVLKHCLRNALIPVVTMMGLQFG
FLLGGSIVVEAVFNWPGLGRLLVDAVTMRDYPVIQTLVLLFSLEFILINLVVDMLYGFINPTIRYK
>Mature_306_residues
MLNYFLKRLLGLLPALLIVAVLVFLFVHMLPGDPARLAAGVDADEATVQVVRQELGLDRPLPEQFVHFFSRMVQGDFGTS
IRTRRPVAAEIGERFMPTLLLTIAAMAWSVVIGMGIGILSAVYRNRWPDRLGMTLAVSGISFPAFALGMTLMQVFSVELG
WLPTVGADSWKHYILPSITLGAAVAAVMARFTRASFVEVVQEDFVRTARAKGLNERTVVLKHCLRNALIPVVTMMGLQFG
FLLGGSIVVEAVFNWPGLGRLLVDAVTMRDYPVIQTLVLLFSLEFILINLVVDMLYGFINPTIRYK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=77.124183006536, Blast_Score=483, Evalue=1e-138,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=41.5929203539823, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1789888, Length=308, Percent_Identity=37.6623376623377, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=40.7975460122699, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=33.7662337662338, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=32.129963898917, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1788504, Length=367, Percent_Identity=25.6130790190736, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33841; Mature: 33841

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYFLKRLLGLLPALLIVAVLVFLFVHMLPGDPARLAAGVDADEATVQVVRQELGLDRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCC
LPEQFVHFFSRMVQGDFGTSIRTRRPVAAEIGERFMPTLLLTIAAMAWSVVIGMGIGILS
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVYRNRWPDRLGMTLAVSGISFPAFALGMTLMQVFSVELGWLPTVGADSWKHYILPSITL
HHHHCCCCHHHCHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHH
GAAVAAVMARFTRASFVEVVQEDFVRTARAKGLNERTVVLKHCLRNALIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEAVFNWPGLGRLLVDAVTMRDYPVIQTLVLLFSLEFILINLVVDMLYGFIN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRYK
CCCCCC
>Mature Secondary Structure
MLNYFLKRLLGLLPALLIVAVLVFLFVHMLPGDPARLAAGVDADEATVQVVRQELGLDRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCC
LPEQFVHFFSRMVQGDFGTSIRTRRPVAAEIGERFMPTLLLTIAAMAWSVVIGMGIGILS
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVYRNRWPDRLGMTLAVSGISFPAFALGMTLMQVFSVELGWLPTVGADSWKHYILPSITL
HHHHCCCCHHHCHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHH
GAAVAAVMARFTRASFVEVVQEDFVRTARAKGLNERTVVLKHCLRNALIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEAVFNWPGLGRLLVDAVTMRDYPVIQTLVLLFSLEFILINLVVDMLYGFIN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRYK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA