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The map label for this gene is hexR [H]

Identifier: 120610338

GI number: 120610338

Start: 1814623

End: 1815576

Strand: Direct

Name: hexR [H]

Synonym: Aave_1655

Alternate gene names: 120610338

Gene position: 1814623-1815576 (Clockwise)

Preceding gene: 120610337

Following gene: 120610339

Centisome position: 33.9

GC content: 72.96

Gene sequence:

>954_bases
ATGTCCGACCTTCCAGAGACCGCCAGCGAGGCCGTGTCGATCGCGATCCGCATCGGCCGCGCGCGCCCCACGCTGACGCG
CTCGCACCAGCAGATGGCGGACTACGTGCTGGCGCATCCGCTGCAGGCGGCCACCATGCCGATCGATGAACTGGCGTCGG
CGGTGGGGGTGTCCATCGCCACGGCGAACCGCTTCGCGCGGGCCGTGGGCCTGGACGGCTATCCGATGCTGCGGGCCGAG
CTGGTGAAGGGCTTCGAGGCCATGCTGGCGCCCATCGAGAAGATGCGCATCAAGCTGGAAAAACCCACGTCCGTGCGCGA
CGTCTTCGCCGCCGCGCTGGAAGAGAGCCAGCGCAATATCGCCGCCACGCGCGAGGCGCTGGACCCGGCCGCCTGCGAGG
CGGCGGTGCAGGCGCTGCTGGGCGCGCGCCGCATCTACCTGGCGGGCTTCGGCGCGAGCGGCTGGCTGGCCGGCCTGCTG
CAGCGCGGGCTGGACGCGCATTGCGACAACGTGCACCTGCTCGCCGGCGTGGGCGGCTCGTCCTACGGCGCGCGCATGCT
GCCGCGCATGGGCGAGGGCGATGTGCTCGTCGCCATCAGCTACCCGCGCTACCTTACCGATACCGTGGTGCTGGCGCAGG
GCGCCTTCGAGCGCGGCGTGCATGTGCTGGCGCTCACCGACGGCCCGCAGTCGCCGCTGGTGCCGTTCGCGCACGGCTGC
CTGTTCGCCCAGACCGAGAACCAGTACGCGGCCAACTCCGAATCGTCGGCGCTGGCCCTCATCGAGGCGCTGACCAGCGC
GGTCGCCCACCAGTCGCGGGAGTCGCTGAAGACGGCCGCCCGCATGACGGAGGCAGTCCTGCCGTGGCTGCACGACAGCG
CCCGCAGCCGGCTCGCGCCGCGATCGGCCGAGTCCGGACCGCGGCGGGCGGAGGCGCGGGGCGCGGGGCGCTGA

Upstream 100 bases:

>100_bases
CTTTGAATGATTGATTTTTTTCTTTAATATGACGTCGTTGTAAATTTTTTCTCAACGCTTTCCGGACGCATTTCCGGCTT
CCGCACCGCATTTCCTGCCC

Downstream 100 bases:

>100_bases
CCGCCCTGCGCCAACGCACCGCCTCCAGCCGCTTCGCCCGTACCGTCCGCTTCGTTCCGTTCCGTTCCCGTCCGCACGCT
TTCCTTTCGCCGCTTCCGCC

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSDLPETASEAVSIAIRIGRARPTLTRSHQQMADYVLAHPLQAATMPIDELASAVGVSIATANRFARAVGLDGYPMLRAE
LVKGFEAMLAPIEKMRIKLEKPTSVRDVFAAALEESQRNIAATREALDPAACEAAVQALLGARRIYLAGFGASGWLAGLL
QRGLDAHCDNVHLLAGVGGSSYGARMLPRMGEGDVLVAISYPRYLTDTVVLAQGAFERGVHVLALTDGPQSPLVPFAHGC
LFAQTENQYAANSESSALALIEALTSAVAHQSRESLKTAARMTEAVLPWLHDSARSRLAPRSAESGPRRAEARGAGR

Sequences:

>Translated_317_residues
MSDLPETASEAVSIAIRIGRARPTLTRSHQQMADYVLAHPLQAATMPIDELASAVGVSIATANRFARAVGLDGYPMLRAE
LVKGFEAMLAPIEKMRIKLEKPTSVRDVFAAALEESQRNIAATREALDPAACEAAVQALLGARRIYLAGFGASGWLAGLL
QRGLDAHCDNVHLLAGVGGSSYGARMLPRMGEGDVLVAISYPRYLTDTVVLAQGAFERGVHVLALTDGPQSPLVPFAHGC
LFAQTENQYAANSESSALALIEALTSAVAHQSRESLKTAARMTEAVLPWLHDSARSRLAPRSAESGPRRAEARGAGR
>Mature_316_residues
SDLPETASEAVSIAIRIGRARPTLTRSHQQMADYVLAHPLQAATMPIDELASAVGVSIATANRFARAVGLDGYPMLRAEL
VKGFEAMLAPIEKMRIKLEKPTSVRDVFAAALEESQRNIAATREALDPAACEAAVQALLGARRIYLAGFGASGWLAGLLQ
RGLDAHCDNVHLLAGVGGSSYGARMLPRMGEGDVLVAISYPRYLTDTVVLAQGAFERGVHVLALTDGPQSPLVPFAHGCL
FAQTENQYAANSESSALALIEALTSAVAHQSRESLKTAARMTEAVLPWLHDSARSRLAPRSAESGPRRAEARGAGR

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082130, Length=251, Percent_Identity=30.6772908366534, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788767, Length=235, Percent_Identity=25.1063829787234, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 33646; Mature: 33515

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPETASEAVSIAIRIGRARPTLTRSHQQMADYVLAHPLQAATMPIDELASAVGVSIA
CCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
TANRFARAVGLDGYPMLRAELVKGFEAMLAPIEKMRIKLEKPTSVRDVFAAALEESQRNI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHH
AATREALDPAACEAAVQALLGARRIYLAGFGASGWLAGLLQRGLDAHCDNVHLLAGVGGS
HHHHHHCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEECCCC
SYGARMLPRMGEGDVLVAISYPRYLTDTVVLAQGAFERGVHVLALTDGPQSPLVPFAHGC
CCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHCHHHCCCEEEEECCCCCCCCCHHHCCE
LFAQTENQYAANSESSALALIEALTSAVAHQSRESLKTAARMTEAVLPWLHDSARSRLAP
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RSAESGPRRAEARGAGR
CCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
SDLPETASEAVSIAIRIGRARPTLTRSHQQMADYVLAHPLQAATMPIDELASAVGVSIA
CCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
TANRFARAVGLDGYPMLRAELVKGFEAMLAPIEKMRIKLEKPTSVRDVFAAALEESQRNI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHH
AATREALDPAACEAAVQALLGARRIYLAGFGASGWLAGLLQRGLDAHCDNVHLLAGVGGS
HHHHHHCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEECCCC
SYGARMLPRMGEGDVLVAISYPRYLTDTVVLAQGAFERGVHVLALTDGPQSPLVPFAHGC
CCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHCHHHCCCEEEEECCCCCCCCCHHHCCE
LFAQTENQYAANSESSALALIEALTSAVAHQSRESLKTAARMTEAVLPWLHDSARSRLAP
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RSAESGPRRAEARGAGR
CCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]