Click here to switch to the map view.

The map label for this gene is frc [H]

Identifier: 120610334

GI number: 120610334

Start: 1810068

End: 1811324

Strand: Direct

Name: frc [H]

Synonym: Aave_1651

Alternate gene names: 120610334

Gene position: 1810068-1811324 (Clockwise)

Preceding gene: 120610329

Following gene: 120610335

Centisome position: 33.82

GC content: 72.32

Gene sequence:

>1257_bases
ATGCAGGAGACGACACCCACGGAATCCAGGGACGCGCAGGCATCCGCCCCGTCCGCCACCCCGACGACCCCCGCGGCCCT
GGCCGGTGTCCGGGTGATCGAGATGGGCCAGCTCATCGCCGGGCCGTTCTGCGGCAAGACCCTGGGCGAATTCGGCGCCG
AGGTGGTGAAGATCGAGGCCACCGGCACGGGCGATCCGCTGCGCAACTGGCGCATGCTCAAGGACGGCACGTCGGTCTGG
TGGCAGGTGCAGTCGCGCAACAAGCGCTCGGTGGCGCTGGACCTGCGCCAGCCTGAGGGGCAGGACATCGCGCGCCGGCT
CATCGCCGAGGCCGACGTGCTCATCGAGAACTTCCGCCCCGGCACGCTGGAGGACTGGGGGATGTCGCCCGAGGCGCTGC
ACGCGCTCAACCCCGGCCTGGTGATCCTGCGCATCTCGGGCTACGGCCAGACGGGCCCCTACCGCGACCTGCCGGGTTTC
GGCGTGATCGGCGAGGCCATGGGCGGCCTGCGGCACCTGACGGGCGAGCCGGGTCGCGTGCCGGTGCGCGTGGGGGTGTC
GATCGGCGACACGCTGGCGGCGCTGCACGGCGCCATCGGCGTGCTCACGGCCCTCTACCACCGCAAGGTGAACGGCGGGC
AGGGGCAGGTGATCGACGTGGCGCTGCACGAGGCGGTGTTCAACGTGATGGAAAGCCTGATCCCCGAATACAGCGCCTTC
GGCGCGGTGCGCGACGCCGCGGGCAGCGCGCTGCCGGGCATCGCCCCTTCCAACGCCTACCCTTGCACGGACGGCTGGGT
GCTGGTGGCGGGCAATGGCGACAGCATCTTCCGGCGGCTGATGGAGGCCATCGGCCGGCCGGACCTCGCCGCGGCGCCCG
ATCTCGCGAACAACGCCGGCCGCGTGGCGCGCGTGCAGGAGATCGACGCCGCGATCGGTGCCTGGACGGCCCGGCGCACC
GTGGCCGAGGTGATGGAGGTGCTCGCCGCCGCGCGCGTGCCCGCCGGCAAGGTCTATACGGCGCGGGACATCGCGGAAGA
CCCGCACTACCGCGCCCGCGACATGCTGCTGCCGCAGGCGACGCGCGACGGCTACACGGTGGAGGTGCCTGGCATCGTGC
CCAAGCTTTCGGCCACGCCGGGCACCATCCGTTCCAGCGCCCCGCAGCTGGGTGACGACACGGACGCGGTGCTGCGCGAG
GCCGGCCTGAGCGATGCCCAGATCGCGCTGCTGCGCGAAAAGGGGGTGGTGCAATGA

Upstream 100 bases:

>100_bases
GATCGAGTTTCATGGGCGCTAGTCTGCCATGCCGTTTTGCGATGGCACCTTCTCGATTGGGCGTTTTGCGGCCGTGCCGG
TGCTGGGCATGATGCGCGCC

Downstream 100 bases:

>100_bases
ACGCCGGCGGCACGGTGTGGCACGGCGCCGGGCGCCGCATCCACATGCAGGAAGTGGGCACGCGCGACGGCCTGCAGATG
GAGCAGGCCTTCGTGCCCAC

Product: formyl-CoA transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MQETTPTESRDAQASAPSATPTTPAALAGVRVIEMGQLIAGPFCGKTLGEFGAEVVKIEATGTGDPLRNWRMLKDGTSVW
WQVQSRNKRSVALDLRQPEGQDIARRLIAEADVLIENFRPGTLEDWGMSPEALHALNPGLVILRISGYGQTGPYRDLPGF
GVIGEAMGGLRHLTGEPGRVPVRVGVSIGDTLAALHGAIGVLTALYHRKVNGGQGQVIDVALHEAVFNVMESLIPEYSAF
GAVRDAAGSALPGIAPSNAYPCTDGWVLVAGNGDSIFRRLMEAIGRPDLAAAPDLANNAGRVARVQEIDAAIGAWTARRT
VAEVMEVLAAARVPAGKVYTARDIAEDPHYRARDMLLPQATRDGYTVEVPGIVPKLSATPGTIRSSAPQLGDDTDAVLRE
AGLSDAQIALLREKGVVQ

Sequences:

>Translated_418_residues
MQETTPTESRDAQASAPSATPTTPAALAGVRVIEMGQLIAGPFCGKTLGEFGAEVVKIEATGTGDPLRNWRMLKDGTSVW
WQVQSRNKRSVALDLRQPEGQDIARRLIAEADVLIENFRPGTLEDWGMSPEALHALNPGLVILRISGYGQTGPYRDLPGF
GVIGEAMGGLRHLTGEPGRVPVRVGVSIGDTLAALHGAIGVLTALYHRKVNGGQGQVIDVALHEAVFNVMESLIPEYSAF
GAVRDAAGSALPGIAPSNAYPCTDGWVLVAGNGDSIFRRLMEAIGRPDLAAAPDLANNAGRVARVQEIDAAIGAWTARRT
VAEVMEVLAAARVPAGKVYTARDIAEDPHYRARDMLLPQATRDGYTVEVPGIVPKLSATPGTIRSSAPQLGDDTDAVLRE
AGLSDAQIALLREKGVVQ
>Mature_418_residues
MQETTPTESRDAQASAPSATPTTPAALAGVRVIEMGQLIAGPFCGKTLGEFGAEVVKIEATGTGDPLRNWRMLKDGTSVW
WQVQSRNKRSVALDLRQPEGQDIARRLIAEADVLIENFRPGTLEDWGMSPEALHALNPGLVILRISGYGQTGPYRDLPGF
GVIGEAMGGLRHLTGEPGRVPVRVGVSIGDTLAALHGAIGVLTALYHRKVNGGQGQVIDVALHEAVFNVMESLIPEYSAF
GAVRDAAGSALPGIAPSNAYPCTDGWVLVAGNGDSIFRRLMEAIGRPDLAAAPDLANNAGRVARVQEIDAAIGAWTARRT
VAEVMEVLAAARVPAGKVYTARDIAEDPHYRARDMLLPQATRDGYTVEVPGIVPKLSATPGTIRSSAPQLGDDTDAVLRE
AGLSDAQIALLREKGVVQ

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=403, Percent_Identity=27.5434243176179, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI300863124, Length=323, Percent_Identity=29.1021671826625, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI300863126, Length=403, Percent_Identity=25.3101736972705, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI42794625, Length=397, Percent_Identity=28.2115869017632, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI266456254, Length=397, Percent_Identity=28.2115869017632, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI13376042, Length=323, Percent_Identity=25.3869969040248, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI266458397, Length=200, Percent_Identity=36, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI266458393, Length=200, Percent_Identity=36, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI266458395, Length=147, Percent_Identity=38.0952380952381, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI42822893, Length=147, Percent_Identity=38.0952380952381, Blast_Score=99, Evalue=8e-21,
Organism=Escherichia coli, GI87082093, Length=335, Percent_Identity=32.2388059701493, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1786222, Length=401, Percent_Identity=29.6758104738155, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1788717, Length=420, Percent_Identity=28.8095238095238, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI115535051, Length=285, Percent_Identity=31.2280701754386, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32564160, Length=213, Percent_Identity=33.8028169014084, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24648431, Length=396, Percent_Identity=31.5656565656566, Blast_Score=198, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24585488, Length=361, Percent_Identity=27.9778393351801, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 44166; Mature: 44166

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQETTPTESRDAQASAPSATPTTPAALAGVRVIEMGQLIAGPFCGKTLGEFGAEVVKIEA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEE
TGTGDPLRNWRMLKDGTSVWWQVQSRNKRSVALDLRQPEGQDIARRLIAEADVLIENFRP
CCCCCHHHCCEEECCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
GTLEDWGMSPEALHALNPGLVILRISGYGQTGPYRDLPGFGVIGEAMGGLRHLTGEPGRV
CCCHHCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
PVRVGVSIGDTLAALHGAIGVLTALYHRKVNGGQGQVIDVALHEAVFNVMESLIPEYSAF
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHH
GAVRDAAGSALPGIAPSNAYPCTDGWVLVAGNGDSIFRRLMEAIGRPDLAAAPDLANNAG
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
RVARVQEIDAAIGAWTARRTVAEVMEVLAAARVPAGKVYTARDIAEDPHYRARDMLLPQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCHHHHCCCCCC
TRDGYTVEVPGIVPKLSATPGTIRSSAPQLGDDTDAVLREAGLSDAQIALLREKGVVQ
CCCCEEEECCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHCCCCHHHEEEEHHCCCCC
>Mature Secondary Structure
MQETTPTESRDAQASAPSATPTTPAALAGVRVIEMGQLIAGPFCGKTLGEFGAEVVKIEA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEE
TGTGDPLRNWRMLKDGTSVWWQVQSRNKRSVALDLRQPEGQDIARRLIAEADVLIENFRP
CCCCCHHHCCEEECCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
GTLEDWGMSPEALHALNPGLVILRISGYGQTGPYRDLPGFGVIGEAMGGLRHLTGEPGRV
CCCHHCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
PVRVGVSIGDTLAALHGAIGVLTALYHRKVNGGQGQVIDVALHEAVFNVMESLIPEYSAF
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHH
GAVRDAAGSALPGIAPSNAYPCTDGWVLVAGNGDSIFRRLMEAIGRPDLAAAPDLANNAG
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
RVARVQEIDAAIGAWTARRTVAEVMEVLAAARVPAGKVYTARDIAEDPHYRARDMLLPQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCHHHHCCCCCC
TRDGYTVEVPGIVPKLSATPGTIRSSAPQLGDDTDAVLREAGLSDAQIALLREKGVVQ
CCCCEEEECCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHCCCCHHHEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA