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The map label for this gene is gbpR [H]

Identifier: 120609450

GI number: 120609450

Start: 811017

End: 811976

Strand: Direct

Name: gbpR [H]

Synonym: Aave_0756

Alternate gene names: 120609450

Gene position: 811017-811976 (Clockwise)

Preceding gene: 120609442

Following gene: 120609452

Centisome position: 15.15

GC content: 70.52

Gene sequence:

>960_bases
ATGCCGGGCAAACCCTTATCCATCGCCACCGCCTGCAGCCGCCTGCGCTCGCGGCACCTGCAGTTCCTGGACATCCTGGG
GAGGACGCGCAACCTGCGGCTCACGGCCGAGCAGATGCACGTGACGCAGCCGGCCGCCACCAAGATCCTGCTGGACCTGG
AGGAGATCTTCGATGCGCGCCTGTTCGAGCGGCTGCCGCGCGAGATGCGCCCCACCGAGCTGGGCCTGTTCGCGCTGGGC
TATGCCGCCTCCGCGCTGGCGGGCCAGGCGAAGTTCGTGGACGAATTCAATGCGCTCAAGCAGGGCGGGCACGGGCAACT
GTCCATCGGCGCCATCTCCGGCTCGGCCGCGCGGCTGCTCACCACGGCCATCGCCGAGATGCAGCGGCGCCGGCCGCTGC
TGGTGCTGAAGGTGCGCGAGCAGAGCAGCGACCAGCTCATCGCCTGGCTGGGCGAGCGCAGGATCGACCTGATGATCGGC
CGCTTCACCGACGAGGCGCAGCAGGCGGATTTCCAGTACGAGCGCCTGTCCGGCGAGACGCTGCAGGTGGTGGGCGGGCC
GCACCATCCGCTGCGCGGCATCCAGGGGCTGGAGGTGGGCCGCCTCGCGCACTGGCCCTGGCTGCTGTACCCGGAATCGA
CGGCGCTGCGCAAGGTGTCCGACGACATCTTCCGGGCCATCGGCATGACGCCGACCTCGGGCGTGATGGAGACGCAGTCC
TTCCTGTTCGCGCTGGAATCGCTGCGCATCACCGACATGCTCTCGCTGCAGCCGAGCGCGCTGGCCGACCGGTACATCGC
CAAGGGCCTGCTCGCCCCCATCCACGTGGACGTGCCCCGGGCGATGCCCGACTACGGCATGCTGGTGCGCCAGGGCGAGA
CACCGACGCCGGCGGCGCAGGCGTTCATGGAGGTGCTGCGGGATGTGGCGGGCGGGAAGGTGGTGGCGGCCCGGCGGTAG

Upstream 100 bases:

>100_bases
TTCCTGGGTGTCGCGGGGGTGCAGACTAGGGGGCGGTGCCCGTGGCGTCCAATCAGTGTTTTTCCACGGGGCATTCCTTC
CAGTTATCGGTCCCCCCAAA

Downstream 100 bases:

>100_bases
GCGCCAGCGGGTCCCCGGTCAGTACGGCAGGATCCCCGGCAACAACTGCCGGTCCAGCCGCTGCCGCCACCACTTGAGCG
CCTCTCCCATGTGGTCGGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MPGKPLSIATACSRLRSRHLQFLDILGRTRNLRLTAEQMHVTQPAATKILLDLEEIFDARLFERLPREMRPTELGLFALG
YAASALAGQAKFVDEFNALKQGGHGQLSIGAISGSAARLLTTAIAEMQRRRPLLVLKVREQSSDQLIAWLGERRIDLMIG
RFTDEAQQADFQYERLSGETLQVVGGPHHPLRGIQGLEVGRLAHWPWLLYPESTALRKVSDDIFRAIGMTPTSGVMETQS
FLFALESLRITDMLSLQPSALADRYIAKGLLAPIHVDVPRAMPDYGMLVRQGETPTPAAQAFMEVLRDVAGGKVVAARR

Sequences:

>Translated_319_residues
MPGKPLSIATACSRLRSRHLQFLDILGRTRNLRLTAEQMHVTQPAATKILLDLEEIFDARLFERLPREMRPTELGLFALG
YAASALAGQAKFVDEFNALKQGGHGQLSIGAISGSAARLLTTAIAEMQRRRPLLVLKVREQSSDQLIAWLGERRIDLMIG
RFTDEAQQADFQYERLSGETLQVVGGPHHPLRGIQGLEVGRLAHWPWLLYPESTALRKVSDDIFRAIGMTPTSGVMETQS
FLFALESLRITDMLSLQPSALADRYIAKGLLAPIHVDVPRAMPDYGMLVRQGETPTPAAQAFMEVLRDVAGGKVVAARR
>Mature_318_residues
PGKPLSIATACSRLRSRHLQFLDILGRTRNLRLTAEQMHVTQPAATKILLDLEEIFDARLFERLPREMRPTELGLFALGY
AASALAGQAKFVDEFNALKQGGHGQLSIGAISGSAARLLTTAIAEMQRRRPLLVLKVREQSSDQLIAWLGERRIDLMIGR
FTDEAQQADFQYERLSGETLQVVGGPHHPLRGIQGLEVGRLAHWPWLLYPESTALRKVSDDIFRAIGMTPTSGVMETQSF
LFALESLRITDMLSLQPSALADRYIAKGLLAPIHVDVPRAMPDYGMLVRQGETPTPAAQAFMEVLRDVAGGKVVAARR

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=301, Percent_Identity=27.2425249169435, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI157672245, Length=307, Percent_Identity=26.7100977198697, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35302; Mature: 35170

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGKPLSIATACSRLRSRHLQFLDILGRTRNLRLTAEQMHVTQPAATKILLDLEEIFDAR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHH
LFERLPREMRPTELGLFALGYAASALAGQAKFVDEFNALKQGGHGQLSIGAISGSAARLL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH
TTAIAEMQRRRPLLVLKVREQSSDQLIAWLGERRIDLMIGRFTDEAQQADFQYERLSGET
HHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCHHHHHCCHHHHCCCCE
LQVVGGPHHPLRGIQGLEVGRLAHWPWLLYPESTALRKVSDDIFRAIGMTPTSGVMETQS
EEEECCCCCCCCCCCCCCCCCEECCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FLFALESLRITDMLSLQPSALADRYIAKGLLAPIHVDVPRAMPDYGMLVRQGETPTPAAQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEECCCCCCHHHH
AFMEVLRDVAGGKVVAARR
HHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
PGKPLSIATACSRLRSRHLQFLDILGRTRNLRLTAEQMHVTQPAATKILLDLEEIFDAR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHH
LFERLPREMRPTELGLFALGYAASALAGQAKFVDEFNALKQGGHGQLSIGAISGSAARLL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH
TTAIAEMQRRRPLLVLKVREQSSDQLIAWLGERRIDLMIGRFTDEAQQADFQYERLSGET
HHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCHHHHHCCHHHHCCCCE
LQVVGGPHHPLRGIQGLEVGRLAHWPWLLYPESTALRKVSDDIFRAIGMTPTSGVMETQS
EEEECCCCCCCCCCCCCCCCCEECCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FLFALESLRITDMLSLQPSALADRYIAKGLLAPIHVDVPRAMPDYGMLVRQGETPTPAAQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEECCCCCCHHHH
AFMEVLRDVAGGKVVAARR
HHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]