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The map label for this gene is glcB [H]

Identifier: 120609111

GI number: 120609111

Start: 438082

End: 440382

Strand: Reverse

Name: glcB [H]

Synonym: Aave_0408

Alternate gene names: 120609111

Gene position: 440382-438082 (Counterclockwise)

Preceding gene: 120609116

Following gene: 120609110

Centisome position: 8.23

GC content: 68.54

Gene sequence:

>2301_bases
ATGCGGATAAAAAATTCAAATACAGTGGCTCCAGCGGGGGATTTCCCCCCGCGTACCTCCTTGTTCCACCCGCCCAATCC
ACCCACCATGACCGATCGCACCTCCGTCCACGGCCTGCAAGTGGCCACGCTTCTGCACCGATTCATCGAAGAGCGCGTGC
TGCCCGGCACGGGCGTCGATGCCGCCGCGTTCTGGTCCGGCTTCGATGCCATCGTGCGGGACCTGGCTCCGCGCAATATC
GCCCTGCTGGCCGAGCGCGACCGCCTGCAATCCGAACTGGACACCTGGCACAAGGCCCACCCCGGCCCGGTCACCGACAT
GGCGGGCTACCGCGCCTTCCTGGAGAAGATCGGCTACCTCGTGCCGCAACCCGCAGGCGTGCAGGCCACCACCGCCAACG
TGGACGACGAACTCGCCATCCAGGCCGGCCCGCAGCTCGTGGTGCCGATCCTGAACGCACGCTACGCGCTCAACGCCGCC
AACGCGCGCTGGGGCAGCCTGTACGACGCGCTCTATGGCACCGACGTCATTTCCGAAGAGGGCGGCGCCGAAAAGGGCAA
GGGCTACAACCCGGTGCGCGGCGCCAGGGTGATCGCCTTCGCGCGCAACGTGCTGGACACCAGCGCCCCGCTCGCCGCCG
GCTCGCACAAGGATGCGAAGGCCTACCGCGTCGAAGGCGGCCGCCTGGCCGTGGAGCTGCAGGACGGCTCGGCCACGGGC
CTGAAGGACGCGGCCCAGTTCGTGGGCTACCAGGGCGATGCCGCCGCACCGTCGTCCGTGCTGCTGCGCCACAACGGGCT
GCACCTGGACATCCGGATCGACCGCTCCACGCCCATCGGCAAGACCGATCCCGCCGGCGTGAGCGACCTGGTGCTGGAAG
CGGCCCTCTCCACCATCCTCGACCTCGAAGACTCCGTCGCCGCCGTCGATGCCGAGGACAAGGTGGCCGGCTATGCCAAC
TGGCTGGGCATCCTGCAGGGCACGCTGACCGAATCCTTCGCCAAGGGCGGCCAGACCGTCACGCGGGGCCTGAACGCCGA
CCGCATCTACACCGCGCCCGGGGGCAGCGGCGAAGTGCGCCTGCACGGCCGCTCGCTCATGTTCCTGCGCAACGTGGGCC
ACCTGATGACCAACCCGGCCGTGCTGTGGACCGACGCGCAGGGCGCGCAGCGCGAGATCCCGGAAGGCATCCTGGACGCG
GTGGTCACCACCGCCATCGCGCTGCACGACCTGCAGGGCAAGGGCCAGGGCGGCATCCGCAACTCGCGCAAGGGCAGCGT
CTATATCGTCAAGCCCAAGATGCACGGCCCGGCCGAAGTGGCCTTCGCCAGCGAACTCTTCGCCCGCGTGGAACGCCTGC
TGGGCCTGCCGGAGAACACCGTCAAGCTGGGCATCATGGACGAAGAGCGCCGCACCAGCGTGAACCTGAAGGCCTGCATC
GCCGCCGCGTCGGCCCGGGTGGCCTTCATCAACACCGGCTTCCTGGACCGCACCGGCGACGAGATGCACACCGCCATGCA
GGCCGGGCCCATGGTGCGCAAGGGCGACATGAAGGCCAGCGCCTGGATCCAGGCCTACGAGAAGAACAACGTGCTGGTGG
GCCTGTCGTGCGGCCTGCGCGGCAAGGCGCAGATCGGCAAGGGCATGTGGGCCATGCCCGACATGATGAAGGCCATGCTG
GAGCAGAAGATCGCCCACCCCAGGGCCGGCGCCAACACCGCCTGGGTGCCCAGCCCCACGGGCGCCACGCTGCACGCCCT
GCATTACCACCAGGTCAACGTGGCCGAGGTGCAGAAGGAGCTGGAAAAGACCAGCGCCGATGCCGAACGCGACAACCTGC
TCACCGGCCTGCTGACCATTCCCGTCGCCGCCAACCCGCAATGGACCGACGCCGAGAAGCAGCAGGAGCTGGACAACAAC
GCCCAGGGCATCCTCGGCTACGTGGTGCGCTGGATCGACCAGGGCGTGGGCTGCTCCAAGGTACCCGACATCCACGACGT
GGGCCTGATGGAAGACCGCGCCACGCTGCGCATCAGCAGCCAGCACATCGCCAACTGGCTGCTGCATGGCGTGGTGACCG
AGGACCAGGTGCGGAAAACCTTCGAGCGCATGGCCGCCGTGGTGGACCAGCAGAACGCGGGTGATCCGGCCTACCGGAAG
ATGGCCGGCCGCTTTGCCGAGTCTGCCGCTTACCAGGCCGCCTGCGACCTGGTGTTCAAGGGCGTGGAGCAGCCCAGCGG
CTATACCGAGCCGCTGCTGCACGCCTGGCGGCTGAAGGTGAAGGCCGGCGCGGCACGCTGA

Upstream 100 bases:

>100_bases
CTGTAACCGCCGGACACACGGATGTTGCACGCCAAGGAGCCGGCCACCCTGCGCGGATTCATGCAAAAAAGTCACGGGTT
CTGCAATTCGCGGGTGGTTT

Downstream 100 bases:

>100_bases
TCCGCCTCCGCGCTGCCCGAAGGCACCCGAGAGGGTGCCTTTTTTCGTGGCGAAAAACCCTCGCCAACCACGGTCACCCT
GGCGGCCTCGCAGGGTGCAA

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 766; Mature: 766

Protein sequence:

>766_residues
MRIKNSNTVAPAGDFPPRTSLFHPPNPPTMTDRTSVHGLQVATLLHRFIEERVLPGTGVDAAAFWSGFDAIVRDLAPRNI
ALLAERDRLQSELDTWHKAHPGPVTDMAGYRAFLEKIGYLVPQPAGVQATTANVDDELAIQAGPQLVVPILNARYALNAA
NARWGSLYDALYGTDVISEEGGAEKGKGYNPVRGARVIAFARNVLDTSAPLAAGSHKDAKAYRVEGGRLAVELQDGSATG
LKDAAQFVGYQGDAAAPSSVLLRHNGLHLDIRIDRSTPIGKTDPAGVSDLVLEAALSTILDLEDSVAAVDAEDKVAGYAN
WLGILQGTLTESFAKGGQTVTRGLNADRIYTAPGGSGEVRLHGRSLMFLRNVGHLMTNPAVLWTDAQGAQREIPEGILDA
VVTTAIALHDLQGKGQGGIRNSRKGSVYIVKPKMHGPAEVAFASELFARVERLLGLPENTVKLGIMDEERRTSVNLKACI
AAASARVAFINTGFLDRTGDEMHTAMQAGPMVRKGDMKASAWIQAYEKNNVLVGLSCGLRGKAQIGKGMWAMPDMMKAML
EQKIAHPRAGANTAWVPSPTGATLHALHYHQVNVAEVQKELEKTSADAERDNLLTGLLTIPVAANPQWTDAEKQQELDNN
AQGILGYVVRWIDQGVGCSKVPDIHDVGLMEDRATLRISSQHIANWLLHGVVTEDQVRKTFERMAAVVDQQNAGDPAYRK
MAGRFAESAAYQAACDLVFKGVEQPSGYTEPLLHAWRLKVKAGAAR

Sequences:

>Translated_766_residues
MRIKNSNTVAPAGDFPPRTSLFHPPNPPTMTDRTSVHGLQVATLLHRFIEERVLPGTGVDAAAFWSGFDAIVRDLAPRNI
ALLAERDRLQSELDTWHKAHPGPVTDMAGYRAFLEKIGYLVPQPAGVQATTANVDDELAIQAGPQLVVPILNARYALNAA
NARWGSLYDALYGTDVISEEGGAEKGKGYNPVRGARVIAFARNVLDTSAPLAAGSHKDAKAYRVEGGRLAVELQDGSATG
LKDAAQFVGYQGDAAAPSSVLLRHNGLHLDIRIDRSTPIGKTDPAGVSDLVLEAALSTILDLEDSVAAVDAEDKVAGYAN
WLGILQGTLTESFAKGGQTVTRGLNADRIYTAPGGSGEVRLHGRSLMFLRNVGHLMTNPAVLWTDAQGAQREIPEGILDA
VVTTAIALHDLQGKGQGGIRNSRKGSVYIVKPKMHGPAEVAFASELFARVERLLGLPENTVKLGIMDEERRTSVNLKACI
AAASARVAFINTGFLDRTGDEMHTAMQAGPMVRKGDMKASAWIQAYEKNNVLVGLSCGLRGKAQIGKGMWAMPDMMKAML
EQKIAHPRAGANTAWVPSPTGATLHALHYHQVNVAEVQKELEKTSADAERDNLLTGLLTIPVAANPQWTDAEKQQELDNN
AQGILGYVVRWIDQGVGCSKVPDIHDVGLMEDRATLRISSQHIANWLLHGVVTEDQVRKTFERMAAVVDQQNAGDPAYRK
MAGRFAESAAYQAACDLVFKGVEQPSGYTEPLLHAWRLKVKAGAAR
>Mature_766_residues
MRIKNSNTVAPAGDFPPRTSLFHPPNPPTMTDRTSVHGLQVATLLHRFIEERVLPGTGVDAAAFWSGFDAIVRDLAPRNI
ALLAERDRLQSELDTWHKAHPGPVTDMAGYRAFLEKIGYLVPQPAGVQATTANVDDELAIQAGPQLVVPILNARYALNAA
NARWGSLYDALYGTDVISEEGGAEKGKGYNPVRGARVIAFARNVLDTSAPLAAGSHKDAKAYRVEGGRLAVELQDGSATG
LKDAAQFVGYQGDAAAPSSVLLRHNGLHLDIRIDRSTPIGKTDPAGVSDLVLEAALSTILDLEDSVAAVDAEDKVAGYAN
WLGILQGTLTESFAKGGQTVTRGLNADRIYTAPGGSGEVRLHGRSLMFLRNVGHLMTNPAVLWTDAQGAQREIPEGILDA
VVTTAIALHDLQGKGQGGIRNSRKGSVYIVKPKMHGPAEVAFASELFARVERLLGLPENTVKLGIMDEERRTSVNLKACI
AAASARVAFINTGFLDRTGDEMHTAMQAGPMVRKGDMKASAWIQAYEKNNVLVGLSCGLRGKAQIGKGMWAMPDMMKAML
EQKIAHPRAGANTAWVPSPTGATLHALHYHQVNVAEVQKELEKTSADAERDNLLTGLLTIPVAANPQWTDAEKQQELDNN
AQGILGYVVRWIDQGVGCSKVPDIHDVGLMEDRATLRISSQHIANWLLHGVVTEDQVRKTFERMAAVVDQQNAGDPAYRK
MAGRFAESAAYQAACDLVFKGVEQPSGYTEPLLHAWRLKVKAGAAR

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=732, Percent_Identity=63.9344262295082, Blast_Score=971, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 82398; Mature: 82398

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIKNSNTVAPAGDFPPRTSLFHPPNPPTMTDRTSVHGLQVATLLHRFIEERVLPGTGVD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
AAAFWSGFDAIVRDLAPRNIALLAERDRLQSELDTWHKAHPGPVTDMAGYRAFLEKIGYL
HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
VPQPAGVQATTANVDDELAIQAGPQLVVPILNARYALNAANARWGSLYDALYGTDVISEE
CCCCCCCEEEECCCCCCEEEECCCEEEEEECCCCEEEECCCCCHHHHHHHHHCCHHHCCC
GGAEKGKGYNPVRGARVIAFARNVLDTSAPLAAGSHKDAKAYRVEGGRLAVELQDGSATG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCC
LKDAAQFVGYQGDAAAPSSVLLRHNGLHLDIRIDRSTPIGKTDPAGVSDLVLEAALSTIL
HHHHHHHCCCCCCCCCCCHHHEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
DLEDSVAAVDAEDKVAGYANWLGILQGTLTESFAKGGQTVTRGLNADRIYTAPGGSGEVR
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCEEE
LHGRSLMFLRNVGHLMTNPAVLWTDAQGAQREIPEGILDAVVTTAIALHDLQGKGQGGIR
ECCCEEHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NSRKGSVYIVKPKMHGPAEVAFASELFARVERLLGLPENTVKLGIMDEERRTSVNLKACI
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHCCCCHHHHH
AAASARVAFINTGFLDRTGDEMHTAMQAGPMVRKGDMKASAWIQAYEKNNVLVGLSCGLR
HHHCCEEEEEECCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHCCCCCEEEEEECCCC
GKAQIGKGMWAMPDMMKAMLEQKIAHPRAGANTAWVPSPTGATLHALHYHQVNVAEVQKE
CCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
LEKTSADAERDNLLTGLLTIPVAANPQWTDAEKQQELDNNAQGILGYVVRWIDQGVGCSK
HHHHCCCCHHHHHEEEHEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
VPDIHDVGLMEDRATLRISSQHIANWLLHGVVTEDQVRKTFERMAAVVDQQNAGDPAYRK
CCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
MAGRFAESAAYQAACDLVFKGVEQPSGYTEPLLHAWRLKVKAGAAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEECCCCC
>Mature Secondary Structure
MRIKNSNTVAPAGDFPPRTSLFHPPNPPTMTDRTSVHGLQVATLLHRFIEERVLPGTGVD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
AAAFWSGFDAIVRDLAPRNIALLAERDRLQSELDTWHKAHPGPVTDMAGYRAFLEKIGYL
HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
VPQPAGVQATTANVDDELAIQAGPQLVVPILNARYALNAANARWGSLYDALYGTDVISEE
CCCCCCCEEEECCCCCCEEEECCCEEEEEECCCCEEEECCCCCHHHHHHHHHCCHHHCCC
GGAEKGKGYNPVRGARVIAFARNVLDTSAPLAAGSHKDAKAYRVEGGRLAVELQDGSATG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCC
LKDAAQFVGYQGDAAAPSSVLLRHNGLHLDIRIDRSTPIGKTDPAGVSDLVLEAALSTIL
HHHHHHHCCCCCCCCCCCHHHEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
DLEDSVAAVDAEDKVAGYANWLGILQGTLTESFAKGGQTVTRGLNADRIYTAPGGSGEVR
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCEEE
LHGRSLMFLRNVGHLMTNPAVLWTDAQGAQREIPEGILDAVVTTAIALHDLQGKGQGGIR
ECCCEEHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NSRKGSVYIVKPKMHGPAEVAFASELFARVERLLGLPENTVKLGIMDEERRTSVNLKACI
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHCCCCHHHHH
AAASARVAFINTGFLDRTGDEMHTAMQAGPMVRKGDMKASAWIQAYEKNNVLVGLSCGLR
HHHCCEEEEEECCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHCCCCCEEEEEECCCC
GKAQIGKGMWAMPDMMKAMLEQKIAHPRAGANTAWVPSPTGATLHALHYHQVNVAEVQKE
CCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
LEKTSADAERDNLLTGLLTIPVAANPQWTDAEKQQELDNNAQGILGYVVRWIDQGVGCSK
HHHHCCCCHHHHHEEEHEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
VPDIHDVGLMEDRATLRISSQHIANWLLHGVVTEDQVRKTFERMAAVVDQQNAGDPAYRK
CCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
MAGRFAESAAYQAACDLVFKGVEQPSGYTEPLLHAWRLKVKAGAAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA