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The map label for this gene is ampG4 [H]

Identifier: 120608979

GI number: 120608979

Start: 306587

End: 307936

Strand: Reverse

Name: ampG4 [H]

Synonym: Aave_0276

Alternate gene names: 120608979

Gene position: 307936-306587 (Counterclockwise)

Preceding gene: 120608984

Following gene: 120608978

Centisome position: 5.75

GC content: 71.11

Gene sequence:

>1350_bases
ATGACACCCTCTCCGCCTGCCCCAGCCCCCTCCGCTCCGCCCGGACCGGCCCGCTCCTGGCGCGCCGCCTGGAAGGTCTA
TGCCGAACCTGCCAGCCTGCGCATGCTCGCCCTGGGTTTCTCCGCCGGCCTGCCGCTGCTGCTGGTGCTGGGCACGCTGT
CGTTCTGGCTGCGCGAGGCGGGCGTGGACCGCACCACCATCGGCTACCTCAGCTGGGTGGGCCTCGCCTACGCCTTCAAA
TGGGTCTGGGCGCCGCTGGTGGACCGCATGCCGCTGCCGCTGCTCACGCGCGCACTGGGCCGGCGCCGCAGCTGGCTGCT
GTTCTCGCAGGCGCTGGTGATGGCGGGCCTGGCGGGCATGGCTTTCAACGATCCGCGCGCGGCCCTCGCGCCCATGGTGT
GGTGCGCGCTGGCCGTGGCCTTCGGCTCGGCCACGCAGGACATCGCGCTGGACGCCTTCCGCATCGAATCGGCCGACGCC
GACCGGCAGGCCGCGCTGGCCGCCACCTACCAGACGGGCTACCGTTTGGCGATGATCTGGGCCGGCGCCGGCGTGCTGTG
GGTGGCCGCACGCGCCGAGGTGCCCGGCCTCGCGGGCTACCAGCACGGGGCCTGGCGCACGGCCTACCTGGTGATGGCCG
CCTCGATGCTGGTGGGCGTGCTCACGGTGCTGCTTTCGCGCGAACCCGCTCCGCGCCCTCTGCCGCCCGCGCGCAATGCG
GCCCAATGGCTGCGCGGCGCGCTGATCGATCCGTTCGCCGATTTCATCGCGCGCTACCGCTGGCAGGCCGCGCTGATCCT
GGCGCTGATCGCCGTGTACCGCATCAGCGACGTGGTGATGGGCATCATGGCCAATCCGTTCTACGTGGACATGGGCTACA
CCAAGGACGAGGTGGCCGCCGTCACCAAGGTGTTCGGCGTCGTCATGACACTGGCCGGCGCGTTCCTCGGGGGCGCGCTG
TCGATGCGCGTGGGCGTGATGCGCGTGCTGATGCTCGGCGCCCTGCTGAGTGCGGCCAGCAACCTGCTGTTCGCCTGGCT
GGGCCTGCAGGAGCACGACGTGACGCTGCTGGTGCTGGTTGTGTCGGCCGACAACCTGGCCGGGGGCATCGCCTCGGCCG
CGTTCATCGCCTACCTCTCGGCCCTCACGAATGTGCAATATTCGGCCACGCAGTACGCGCTGTTCAGCTCGATGATGCTG
TTGCTGCCGAAATGGCTCGCCGGTTTCTCGGGGCGTTTCGTGGATGCCTTCGGCTACCCCGAGTTCTTCGCGGCCACGGC
GATGCTGGGCCTGCCCGTGCTGGCGCTGGTGGCGCTGGCCGCGCGCGCGCAGCAGCGCCCGCCGGGCTGA

Upstream 100 bases:

>100_bases
TCAACAGCATCGCCCTGACGGAACACAGACGAAAATCCATGCCGGTGCGCGAAAGACCCCGACGCACTCCGCGCTCTTCC
ACTGCCGCCTCCCGCCCCCC

Downstream 100 bases:

>100_bases
ACGCAGCCGGTTTACCGAAACTTTACGGCCACTTCAACGCCCCGAGATGCACCGGGGCCAGCATGCCATCCTGCCTTTGC
GCAAGGAGACGAGAGACGCC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTPSPPAPAPSAPPGPARSWRAAWKVYAEPASLRMLALGFSAGLPLLLVLGTLSFWLREAGVDRTTIGYLSWVGLAYAFK
WVWAPLVDRMPLPLLTRALGRRRSWLLFSQALVMAGLAGMAFNDPRAALAPMVWCALAVAFGSATQDIALDAFRIESADA
DRQAALAATYQTGYRLAMIWAGAGVLWVAARAEVPGLAGYQHGAWRTAYLVMAASMLVGVLTVLLSREPAPRPLPPARNA
AQWLRGALIDPFADFIARYRWQAALILALIAVYRISDVVMGIMANPFYVDMGYTKDEVAAVTKVFGVVMTLAGAFLGGAL
SMRVGVMRVLMLGALLSAASNLLFAWLGLQEHDVTLLVLVVSADNLAGGIASAAFIAYLSALTNVQYSATQYALFSSMML
LLPKWLAGFSGRFVDAFGYPEFFAATAMLGLPVLALVALAARAQQRPPG

Sequences:

>Translated_449_residues
MTPSPPAPAPSAPPGPARSWRAAWKVYAEPASLRMLALGFSAGLPLLLVLGTLSFWLREAGVDRTTIGYLSWVGLAYAFK
WVWAPLVDRMPLPLLTRALGRRRSWLLFSQALVMAGLAGMAFNDPRAALAPMVWCALAVAFGSATQDIALDAFRIESADA
DRQAALAATYQTGYRLAMIWAGAGVLWVAARAEVPGLAGYQHGAWRTAYLVMAASMLVGVLTVLLSREPAPRPLPPARNA
AQWLRGALIDPFADFIARYRWQAALILALIAVYRISDVVMGIMANPFYVDMGYTKDEVAAVTKVFGVVMTLAGAFLGGAL
SMRVGVMRVLMLGALLSAASNLLFAWLGLQEHDVTLLVLVVSADNLAGGIASAAFIAYLSALTNVQYSATQYALFSSMML
LLPKWLAGFSGRFVDAFGYPEFFAATAMLGLPVLALVALAARAQQRPPG
>Mature_448_residues
TPSPPAPAPSAPPGPARSWRAAWKVYAEPASLRMLALGFSAGLPLLLVLGTLSFWLREAGVDRTTIGYLSWVGLAYAFKW
VWAPLVDRMPLPLLTRALGRRRSWLLFSQALVMAGLAGMAFNDPRAALAPMVWCALAVAFGSATQDIALDAFRIESADAD
RQAALAATYQTGYRLAMIWAGAGVLWVAARAEVPGLAGYQHGAWRTAYLVMAASMLVGVLTVLLSREPAPRPLPPARNAA
QWLRGALIDPFADFIARYRWQAALILALIAVYRISDVVMGIMANPFYVDMGYTKDEVAAVTKVFGVVMTLAGAFLGGALS
MRVGVMRVLMLGALLSAASNLLFAWLGLQEHDVTLLVLVVSADNLAGGIASAAFIAYLSALTNVQYSATQYALFSSMMLL
LPKWLAGFSGRFVDAFGYPEFFAATAMLGLPVLALVALAARAQQRPPG

Specific function: Probably Acts As A Permease In The Beta-Lactamase Induction System And In Peptidoglycan Recycling. [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786636, Length=423, Percent_Identity=33.806146572104, Blast_Score=216, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48030; Mature: 47899

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSPPAPAPSAPPGPARSWRAAWKVYAEPASLRMLALGFSAGLPLLLVLGTLSFWLREA
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHH
GVDRTTIGYLSWVGLAYAFKWVWAPLVDRMPLPLLTRALGRRRSWLLFSQALVMAGLAGM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
AFNDPRAALAPMVWCALAVAFGSATQDIALDAFRIESADADRQAALAATYQTGYRLAMIW
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCHHHHHHHHHHCCCEEEEEE
AGAGVLWVAARAEVPGLAGYQHGAWRTAYLVMAASMLVGVLTVLLSREPAPRPLPPARNA
ECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
AQWLRGALIDPFADFIARYRWQAALILALIAVYRISDVVMGIMANPFYVDMGYTKDEVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHH
VTKVFGVVMTLAGAFLGGALSMRVGVMRVLMLGALLSAASNLLFAWLGLQEHDVTLLVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
VSADNLAGGIASAAFIAYLSALTNVQYSATQYALFSSMMLLLPKWLAGFSGRFVDAFGYP
EECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCH
EFFAATAMLGLPVLALVALAARAQQRPPG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TPSPPAPAPSAPPGPARSWRAAWKVYAEPASLRMLALGFSAGLPLLLVLGTLSFWLREA
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHH
GVDRTTIGYLSWVGLAYAFKWVWAPLVDRMPLPLLTRALGRRRSWLLFSQALVMAGLAGM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
AFNDPRAALAPMVWCALAVAFGSATQDIALDAFRIESADADRQAALAATYQTGYRLAMIW
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCHHHHHHHHHHCCCEEEEEE
AGAGVLWVAARAEVPGLAGYQHGAWRTAYLVMAASMLVGVLTVLLSREPAPRPLPPARNA
ECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
AQWLRGALIDPFADFIARYRWQAALILALIAVYRISDVVMGIMANPFYVDMGYTKDEVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHH
VTKVFGVVMTLAGAFLGGALSMRVGVMRVLMLGALLSAASNLLFAWLGLQEHDVTLLVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
VSADNLAGGIASAAFIAYLSALTNVQYSATQYALFSSMMLLLPKWLAGFSGRFVDAFGYP
EECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCH
EFFAATAMLGLPVLALVALAARAQQRPPG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]