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The map label for this gene is ompR [H]

Identifier: 120608978

GI number: 120608978

Start: 305767

End: 306486

Strand: Reverse

Name: ompR [H]

Synonym: Aave_0275

Alternate gene names: 120608978

Gene position: 306486-305767 (Counterclockwise)

Preceding gene: 120608979

Following gene: 120608977

Centisome position: 5.73

GC content: 71.25

Gene sequence:

>720_bases
ATGAGTACCGCCCAGCTGTTGATGATCGAAGACGACTTCCGCCTCGCGCAGATGGTCATCGAATACCTCGGCCAGTCGGG
CCTGGAGGTCGCGCACATGGCCGACGGCCAGAGCGGCATGGCGCGGCTGCAGGGCAGCGATGCCGGCCCGCTGCCCGACC
TCGTGATCCTGGACCTGATGCTGCCCGACATGGACGGCCTGGACGTGTGCCGCCGCATCCGCTCGCTGCCCGGCGCCGCG
GCCCAGGTGCCGGTGCTGATGCTCACCGCCAAGGGCGACCCCATGGACCGCATCATCGGGCTGGAACTCGGCGCCGACGA
CTACCTGCCCAAGCCCTTCGAGCCGCGCGAGCTGCTGGCCCGCATCCGCGCCATCCTGCGGCGCCGCGAGACCGGGCCGG
CGGCGCCCTCGCAGGCCCTGCGCTTCGGCTCGCTGGAGATCGACCGCGACGCACGCTCCGTCACGGTGGGCGGGCAACCG
GCCGACCTCACCTCCTACCAGTTCGACCTGCTCGTGGCGCTCGCGGAGCGGGCCGGCCGCGTGCTCACGCGCGACCAGAT
CATGGAGGCCGTGCGCGGCCGCGAACTGGAAGCCTTCGACCGCTCCATCGACGTGCACATGGGGCGCATCCGCGCCGCGA
TCGAGTCCGACCCCAAGAACCCCCGCCGCATCCTGACCGTGCGAGGCGTCGGGTACGTGTTCGCCAAACAGCAGGACTGA

Upstream 100 bases:

>100_bases
ACGCAGCCGGTTTACCGAAACTTTACGGCCACTTCAACGCCCCGAGATGCACCGGGGCCAGCATGCCATCCTGCCTTTGC
GCAAGGAGACGAGAGACGCC

Downstream 100 bases:

>100_bases
AGATGGAGGCATCATTCCCCTGTGGCGCCACGCGCCTTCCCCCTTCTCTCGCCGCGCTGCGCGCGGCGGGACGGGGGACG
ACGCCAGTGGCCGGGCGAAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSTAQLLMIEDDFRLAQMVIEYLGQSGLEVAHMADGQSGMARLQGSDAGPLPDLVILDLMLPDMDGLDVCRRIRSLPGAA
AQVPVLMLTAKGDPMDRIIGLELGADDYLPKPFEPRELLARIRAILRRRETGPAAPSQALRFGSLEIDRDARSVTVGGQP
ADLTSYQFDLLVALAERAGRVLTRDQIMEAVRGRELEAFDRSIDVHMGRIRAAIESDPKNPRRILTVRGVGYVFAKQQD

Sequences:

>Translated_239_residues
MSTAQLLMIEDDFRLAQMVIEYLGQSGLEVAHMADGQSGMARLQGSDAGPLPDLVILDLMLPDMDGLDVCRRIRSLPGAA
AQVPVLMLTAKGDPMDRIIGLELGADDYLPKPFEPRELLARIRAILRRRETGPAAPSQALRFGSLEIDRDARSVTVGGQP
ADLTSYQFDLLVALAERAGRVLTRDQIMEAVRGRELEAFDRSIDVHMGRIRAAIESDPKNPRRILTVRGVGYVFAKQQD
>Mature_238_residues
STAQLLMIEDDFRLAQMVIEYLGQSGLEVAHMADGQSGMARLQGSDAGPLPDLVILDLMLPDMDGLDVCRRIRSLPGAAA
QVPVLMLTAKGDPMDRIIGLELGADDYLPKPFEPRELLARIRAILRRRETGPAAPSQALRFGSLEIDRDARSVTVGGQPA
DLTSYQFDLLVALAERAGRVLTRDQIMEAVRGRELEAFDRSIDVHMGRIRAAIESDPKNPRRILTVRGVGYVFAKQQD

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=45.1476793248945, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=35.7758620689655, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=35.6223175965665, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=35.0210970464135, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=36.4406779661017, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=38.961038961039, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=36.5217391304348, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=35.4978354978355, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790863, Length=242, Percent_Identity=33.0578512396694, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=34.7280334728033, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=36.9098712446352, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=30.0847457627119, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=240, Percent_Identity=35.4166666666667, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=31.6017316017316, Blast_Score=111, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26291; Mature: 26160

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAQLLMIEDDFRLAQMVIEYLGQSGLEVAHMADGQSGMARLQGSDAGPLPDLVILDLM
CCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCCHHEECCCCCCCCCHHHHHHHH
LPDMDGLDVCRRIRSLPGAAAQVPVLMLTAKGDPMDRIIGLELGADDYLPKPFEPRELLA
CCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCCHHHHHH
RIRAILRRRETGPAAPSQALRFGSLEIDRDARSVTVGGQPADLTSYQFDLLVALAERAGR
HHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCC
VLTRDQIMEAVRGRELEAFDRSIDVHMGRIRAAIESDPKNPRRILTVRGVGYVFAKQQD
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCC
>Mature Secondary Structure 
STAQLLMIEDDFRLAQMVIEYLGQSGLEVAHMADGQSGMARLQGSDAGPLPDLVILDLM
CCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCCHHEECCCCCCCCCHHHHHHHH
LPDMDGLDVCRRIRSLPGAAAQVPVLMLTAKGDPMDRIIGLELGADDYLPKPFEPRELLA
CCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCCHHHHHH
RIRAILRRRETGPAAPSQALRFGSLEIDRDARSVTVGGQPADLTSYQFDLLVALAERAGR
HHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCC
VLTRDQIMEAVRGRELEAFDRSIDVHMGRIRAAIESDPKNPRRILTVRGVGYVFAKQQD
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]