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The map label for this gene is yegE [C]

Identifier: 120608925

GI number: 120608925

Start: 244923

End: 246410

Strand: Reverse

Name: yegE [C]

Synonym: Aave_0220

Alternate gene names: 120608925

Gene position: 246410-244923 (Counterclockwise)

Preceding gene: 120608927

Following gene: 120608919

Centisome position: 4.6

GC content: 68.21

Gene sequence:

>1488_bases
ATGAAGAGGGATTTCCTGCCATCCGATTCGACGGGCCGCTTCCTGGCCCTGCTTGCACTGACGATGATCGCCGCCCAGGT
GGTGGCCTTCGTCTTCCTGCATTTTTCCAACCGGCGGATCGCCATGAACAGCGTGGATGCCGCACTGGAGGCGGGCGCGC
AGACCTTCGAGTACACGGCCGCGATGCGGCGCGAATCCCGGCGGGTGGCCTCCGAGCTGATCTCCCGGGACTACGGCCTG
CAGAACATCATCTTCAACGAGACCAACCGGGACACGGTGGAGTCGGCGCTCTACAACCAGCTGGCGCGGACCGGCGCCGA
ACTGATCGTGCTCACGGACCTGGACGGCACGCTGCGGGCGCGCTCGTCCGTGTCCGGGTTCCTGCGCGAGCGGGACGCGG
CGCTGGACCACCGGCTGGAGCTGCTGGTGGCAAGCGTCCGCGAAGCGAGCCGCAACATGCGCACCATGGACGGGGAAGAC
GGCAAGCCCGTGCTGCACAACTGGGTCAAGGTGACGGTACGGGCACCCGTGCCCGTGGCGCACATCTACCTGGCCTTCCG
GATCACGCACGCCGGCGCCCAGCAGTTCGCGCGCATGACGCAGCTGCAGATGGCTTTCCTCTCCCACGATGCCGAAGCCC
ACTACATCGTCCACGCGAGTACCCTGCCCGTGTCCATCCCCATGGACGGCATCGGCCGGCACGCCAAGGACCAGAGGCCT
TTCTCCGCCAGCGACCCCGACGGCGCCGGCTACCGGGTCAAGGTCATCACGCTGGACGACTCCGGCCCCCTTCCCGTCAG
CGCCGTGGTGGCCAAGCCCTTCGCGCCGGTCATGTCGCCGTTTCTCAAGCTGGAGGCGCTGTTCGCCTTCAGCGTGCTGA
TGAGCGCGGTCATCTCCATCGTCGCGGTCAAGGTGGTGGCCAGCCGTGTGGTGACGCCCCTGGAGGACGTGGCGCAGAAG
GATGCGCTCACCGGGCTCGCCAACCGCCGCACTTTCGATGCCCGGCTGCTGCGTGCCGAACAGGATCTGCAGAGGTCGGG
CACGGGCTTCGCTGTGATGCTGATGGACCTCGACAAGTTCAAGTCCGTCAACGACACCTACGGGCATGACGCGGGCGACG
TGGTGCTCAAGGAAGCCGCGGCCCGCATCCAGAAGATCATCCGCTCGTCCGACACGCTGGCCCGGCTGGGCGGCGACGAG
TTCGCGATCCTCGTGCGCACCGACGACCCGCAGACGCTGTCCCACATCGCCACCGCCATCGTCGAGGTGGTGCGCCAGCC
CATTCCCCTGCAGCCCGGCCTGGCGGCCGAAGTGGGCACCAGCATCGGCATCGCCTTCGCCCCCGCGCACTCCCGGCGCG
GCGCCGAGGTGGTGCATTGGGCCGACCAGGCGATGTACACGGCCAAGCGGCGCGGGGGCGGGTTCGCCATGGCGGAGAGC
GCGAAATCGGCGGCGGAGGCATCGCTGGACATCGCGTCGCAACGGTGA

Upstream 100 bases:

>100_bases
GGCGCAGGGGAATAGAAAGAGATCAGGCAGGGCACCATCGGCGGGCACCCGCCCTGCCGAGGGAACGCGCTTGCCCGCGC
ATTGCACAAGAAGAGCACGC

Downstream 100 bases:

>100_bases
CCGCTCCGCTCCGGCTCAGGCCCCCTGCCCCATCGCCGGATCGGACACGGAATGCCGGCCCGTCTCGACGCGGCCCGCGA
AGCGGCGCACGAAGGCAGGG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MKRDFLPSDSTGRFLALLALTMIAAQVVAFVFLHFSNRRIAMNSVDAALEAGAQTFEYTAAMRRESRRVASELISRDYGL
QNIIFNETNRDTVESALYNQLARTGAELIVLTDLDGTLRARSSVSGFLRERDAALDHRLELLVASVREASRNMRTMDGED
GKPVLHNWVKVTVRAPVPVAHIYLAFRITHAGAQQFARMTQLQMAFLSHDAEAHYIVHASTLPVSIPMDGIGRHAKDQRP
FSASDPDGAGYRVKVITLDDSGPLPVSAVVAKPFAPVMSPFLKLEALFAFSVLMSAVISIVAVKVVASRVVTPLEDVAQK
DALTGLANRRTFDARLLRAEQDLQRSGTGFAVMLMDLDKFKSVNDTYGHDAGDVVLKEAAARIQKIIRSSDTLARLGGDE
FAILVRTDDPQTLSHIATAIVEVVRQPIPLQPGLAAEVGTSIGIAFAPAHSRRGAEVVHWADQAMYTAKRRGGGFAMAES
AKSAAEASLDIASQR

Sequences:

>Translated_495_residues
MKRDFLPSDSTGRFLALLALTMIAAQVVAFVFLHFSNRRIAMNSVDAALEAGAQTFEYTAAMRRESRRVASELISRDYGL
QNIIFNETNRDTVESALYNQLARTGAELIVLTDLDGTLRARSSVSGFLRERDAALDHRLELLVASVREASRNMRTMDGED
GKPVLHNWVKVTVRAPVPVAHIYLAFRITHAGAQQFARMTQLQMAFLSHDAEAHYIVHASTLPVSIPMDGIGRHAKDQRP
FSASDPDGAGYRVKVITLDDSGPLPVSAVVAKPFAPVMSPFLKLEALFAFSVLMSAVISIVAVKVVASRVVTPLEDVAQK
DALTGLANRRTFDARLLRAEQDLQRSGTGFAVMLMDLDKFKSVNDTYGHDAGDVVLKEAAARIQKIIRSSDTLARLGGDE
FAILVRTDDPQTLSHIATAIVEVVRQPIPLQPGLAAEVGTSIGIAFAPAHSRRGAEVVHWADQAMYTAKRRGGGFAMAES
AKSAAEASLDIASQR
>Mature_495_residues
MKRDFLPSDSTGRFLALLALTMIAAQVVAFVFLHFSNRRIAMNSVDAALEAGAQTFEYTAAMRRESRRVASELISRDYGL
QNIIFNETNRDTVESALYNQLARTGAELIVLTDLDGTLRARSSVSGFLRERDAALDHRLELLVASVREASRNMRTMDGED
GKPVLHNWVKVTVRAPVPVAHIYLAFRITHAGAQQFARMTQLQMAFLSHDAEAHYIVHASTLPVSIPMDGIGRHAKDQRP
FSASDPDGAGYRVKVITLDDSGPLPVSAVVAKPFAPVMSPFLKLEALFAFSVLMSAVISIVAVKVVASRVVTPLEDVAQK
DALTGLANRRTFDARLLRAEQDLQRSGTGFAVMLMDLDKFKSVNDTYGHDAGDVVLKEAAARIQKIIRSSDTLARLGGDE
FAILVRTDDPQTLSHIATAIVEVVRQPIPLQPGLAAEVGTSIGIAFAPAHSRRGAEVVHWADQAMYTAKRRGGGFAMAES
AKSAAEASLDIASQR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=171, Percent_Identity=39.1812865497076, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=36.875, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI145693134, Length=182, Percent_Identity=31.8681318681319, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787541, Length=160, Percent_Identity=37.5, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786584, Length=197, Percent_Identity=28.9340101522843, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87081974, Length=150, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=34.1772151898734, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788085, Length=165, Percent_Identity=34.5454545454545, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87081881, Length=183, Percent_Identity=32.2404371584699, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=34.1176470588235, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=150, Percent_Identity=29.3333333333333, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787802, Length=131, Percent_Identity=34.3511450381679, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082007, Length=215, Percent_Identity=28.8372093023256, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 53817; Mature: 53817

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDFLPSDSTGRFLALLALTMIAAQVVAFVFLHFSNRRIAMNSVDAALEAGAQTFEYTA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCHHHHHHH
AMRRESRRVASELISRDYGLQNIIFNETNRDTVESALYNQLARTGAELIVLTDLDGTLRA
HHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
RSSVSGFLRERDAALDHRLELLVASVREASRNMRTMDGEDGKPVLHNWVKVTVRAPVPVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEEEEECCCCHH
HIYLAFRITHAGAQQFARMTQLQMAFLSHDAEAHYIVHASTLPVSIPMDGIGRHAKDQRP
HEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCHHHCCCCCCCCCC
FSASDPDGAGYRVKVITLDDSGPLPVSAVVAKPFAPVMSPFLKLEALFAFSVLMSAVISI
CCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVKVVASRVVTPLEDVAQKDALTGLANRRTFDARLLRAEQDLQRSGTGFAVMLMDLDKF
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHH
KSVNDTYGHDAGDVVLKEAAARIQKIIRSSDTLARLGGDEFAILVRTDDPQTLSHIATAI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHH
VEVVRQPIPLQPGLAAEVGTSIGIAFAPAHSRRGAEVVHWADQAMYTAKRRGGGFAMAES
HHHHHCCCCCCCCCHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
AKSAAEASLDIASQR
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRDFLPSDSTGRFLALLALTMIAAQVVAFVFLHFSNRRIAMNSVDAALEAGAQTFEYTA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCHHHHHHH
AMRRESRRVASELISRDYGLQNIIFNETNRDTVESALYNQLARTGAELIVLTDLDGTLRA
HHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
RSSVSGFLRERDAALDHRLELLVASVREASRNMRTMDGEDGKPVLHNWVKVTVRAPVPVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEEEEECCCCHH
HIYLAFRITHAGAQQFARMTQLQMAFLSHDAEAHYIVHASTLPVSIPMDGIGRHAKDQRP
HEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCHHHCCCCCCCCCC
FSASDPDGAGYRVKVITLDDSGPLPVSAVVAKPFAPVMSPFLKLEALFAFSVLMSAVISI
CCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVKVVASRVVTPLEDVAQKDALTGLANRRTFDARLLRAEQDLQRSGTGFAVMLMDLDKF
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHH
KSVNDTYGHDAGDVVLKEAAARIQKIIRSSDTLARLGGDEFAILVRTDDPQTLSHIATAI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHH
VEVVRQPIPLQPGLAAEVGTSIGIAFAPAHSRRGAEVVHWADQAMYTAKRRGGGFAMAES
HHHHHCCCCCCCCCHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
AKSAAEASLDIASQR
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]