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The map label for this gene is uxuR [H]

Identifier: 120608919

GI number: 120608919

Start: 234545

End: 235312

Strand: Reverse

Name: uxuR [H]

Synonym: Aave_0212

Alternate gene names: 120608919

Gene position: 235312-234545 (Counterclockwise)

Preceding gene: 120608925

Following gene: 120608918

Centisome position: 4.4

GC content: 74.09

Gene sequence:

>768_bases
ATGCACCGCATTCCCTCCTCCGTCGCGCAGACGCTGCAGCAGCAGATCCTGAGCGGCCACTACGCCAGCGGCAGCCCGCT
GCCCGCGCAGCGCGAACTGGCGCAGCGCCTGGGCATCAGCCGGGCCTCGCTGCGCGAGGCGCTGTCGGTGCTGGAGACGC
TGGGCCTGGTGGACATCCTGCCCGGCCGGGGCGTGATGGTGCGGGGCCCGCATGCCAGCGGCGAGCGCACGCACCGCGCC
TTCGCCACGCCCGAGATGGGCACCCTCTCGCCGCGCCAGCTGATCGAGCTGCGGCTGGTGCTGGAGCCCGGATGGACAGC
CCTGGCCGCCGGCCGCGCCGACGCGGGCGCGCACCACCAGTTGCAGTGGCTGCAACAGCAGCAATCCGAAGCGCTGCGGC
GCAACGACCTGCTGAGCGCCGCCGAGGCGGACCTGCATTTCCACCTGCTGCTGGCGCAGTGGTCGGGCAACCCCGGCCTG
ATCGCCATGGCGCGGCAGCTGGAGCCGGCCATCGCCCACAGCCTGCGCCTGCCTTTCGCCCGCACGGGTGCCGACGACGA
GCCCGCGCGCGAGCACGGCGCGATCGTGCAGGCGCTGCGCGCGGGCGATGCCACGGCCAGCGCCCAGGCCATGCACGCCC
ACCTGCTGTCGGCGGCGCGCCGCGGCGGCATCGACATGGATGCGCCGGAGGCCCCCGCGGCCGGCGCGCCGGCTTCCTTT
CGCCTCGTTCCCCCCTCTCCCCCTTTCCCTGAAGGAGTTTTCCAATGA

Upstream 100 bases:

>100_bases
ATCCACCCTCGGTGGGTTGCTCCTTTTTTTGATACTGGCACGCAAATCGCTTTTGGCTGGGCACTGGTCTGACCTGTCAG
GCCACCGATCCACCGAGCCC

Downstream 100 bases:

>100_bases
CCCGCACCGCCACTTCCCCCTCGACCGCCCGCCGCGGCGCCCTCCACGCCCTGCTGGCCGCCACGGCCTTCGCGGCCGCA
GCCCTGGGCGGCGCGGCGTC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MHRIPSSVAQTLQQQILSGHYASGSPLPAQRELAQRLGISRASLREALSVLETLGLVDILPGRGVMVRGPHASGERTHRA
FATPEMGTLSPRQLIELRLVLEPGWTALAAGRADAGAHHQLQWLQQQQSEALRRNDLLSAAEADLHFHLLLAQWSGNPGL
IAMARQLEPAIAHSLRLPFARTGADDEPAREHGAIVQALRAGDATASAQAMHAHLLSAARRGGIDMDAPEAPAAGAPASF
RLVPPSPPFPEGVFQ

Sequences:

>Translated_255_residues
MHRIPSSVAQTLQQQILSGHYASGSPLPAQRELAQRLGISRASLREALSVLETLGLVDILPGRGVMVRGPHASGERTHRA
FATPEMGTLSPRQLIELRLVLEPGWTALAAGRADAGAHHQLQWLQQQQSEALRRNDLLSAAEADLHFHLLLAQWSGNPGL
IAMARQLEPAIAHSLRLPFARTGADDEPAREHGAIVQALRAGDATASAQAMHAHLLSAARRGGIDMDAPEAPAAGAPASF
RLVPPSPPFPEGVFQ
>Mature_255_residues
MHRIPSSVAQTLQQQILSGHYASGSPLPAQRELAQRLGISRASLREALSVLETLGLVDILPGRGVMVRGPHASGERTHRA
FATPEMGTLSPRQLIELRLVLEPGWTALAAGRADAGAHHQLQWLQQQQSEALRRNDLLSAAEADLHFHLLLAQWSGNPGL
IAMARQLEPAIAHSLRLPFARTGADDEPAREHGAIVQALRAGDATASAQAMHAHLLSAARRGGIDMDAPEAPAAGAPASF
RLVPPSPPFPEGVFQ

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=220, Percent_Identity=30, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994955, Length=223, Percent_Identity=30.0448430493274, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082208, Length=222, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994961, Length=221, Percent_Identity=30.316742081448, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790780, Length=227, Percent_Identity=28.1938325991189, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789353, Length=210, Percent_Identity=28.0952380952381, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786303, Length=222, Percent_Identity=27.4774774774775, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27201; Mature: 27201

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRIPSSVAQTLQQQILSGHYASGSPLPAQRELAQRLGISRASLREALSVLETLGLVDIL
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEC
PGRGVMVRGPHASGERTHRAFATPEMGTLSPRQLIELRLVLEPGWTALAAGRADAGAHHQ
CCCCEEEECCCCCCCCCHHHCCCCCCCCCCHHHHHEEHEEECCCCCEEECCCCCCCHHHH
LQWLQQQQSEALRRNDLLSAAEADLHFHLLLAQWSGNPGLIAMARQLEPAIAHSLRLPFA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHH
RTGADDEPAREHGAIVQALRAGDATASAQAMHAHLLSAARRGGIDMDAPEAPAAGAPASF
HCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
RLVPPSPPFPEGVFQ
EECCCCCCCCCCCCC
>Mature Secondary Structure
MHRIPSSVAQTLQQQILSGHYASGSPLPAQRELAQRLGISRASLREALSVLETLGLVDIL
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEC
PGRGVMVRGPHASGERTHRAFATPEMGTLSPRQLIELRLVLEPGWTALAAGRADAGAHHQ
CCCCEEEECCCCCCCCCHHHCCCCCCCCCCHHHHHEEHEEECCCCCEEECCCCCCCHHHH
LQWLQQQQSEALRRNDLLSAAEADLHFHLLLAQWSGNPGLIAMARQLEPAIAHSLRLPFA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHH
RTGADDEPAREHGAIVQALRAGDATASAQAMHAHLLSAARRGGIDMDAPEAPAAGAPASF
HCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
RLVPPSPPFPEGVFQ
EECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]