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The map label for this gene is tcp [H]

Identifier: 120608876

GI number: 120608876

Start: 186648

End: 188114

Strand: Reverse

Name: tcp [H]

Synonym: Aave_0168

Alternate gene names: 120608876

Gene position: 188114-186648 (Counterclockwise)

Preceding gene: 120608877

Following gene: 120608871

Centisome position: 3.51

GC content: 71.92

Gene sequence:

>1467_bases
ATGGGCAAAGCGAAACGAGGCCGCGACCTCTCCCCCAGCGCGCAACAGGCCCTGCAGACCATAGCCTGCCGGGCGGATGC
CCTTCTGCTGGCCATCTGTGCCCTCGGCGCGATCGTCGCGCTATGGATCGGTTTCGTATATGGCCGGCCCGGTACCGCAG
CGATCTGGGGTGGTGCCCTGATGGCGCTGGCCGCATGGGCCTACCTGGCGGTGCGCGGCAGCCTGCTGGGCCGGCTGGCG
CTCGTGACCGCCGGCATCGGGCTGGTGGCCCTGCACATCCAGCTCAGCCTGGGCGCCACCGAGATGCATTTCGGCGTCTT
CGTCTTCCTGGCCTTCGTGCTGGCCTACCGCGACTGGCGGCCCGTCGTCTTCGCGGCAGTGCTGATCGCCGTGCACCACA
TCGCGTTCGATCGCCTGCAGCTGGCCGGGGGCCCGGTGTACTGCCTTACCGAACCCGACTTCGGGCGCGTCCTGGTACAC
GCCGCGTTCGTGGTCGTGCAGACCGCGGTGGAGGTGGCCATCACCCTGCGCACCCGCGCCGATGCGATCGAATCGGCGGA
ACTCCAGTACCTGTGCCGCCCCCAGCAGGACGGCCAGCTGTCGCTGGACGTGCGCGGCGTGCCGGTGGACAGCGCCGCGG
CCCGGGCCCTGCAGGCCGCGCTGCTGCGGCTCAACGGGGTGGTGACCGATGTCCACCAGGCCGCGGCGGGCCTGGCGGCG
GCGGCGGGCGAGATCGCCACGGGCAACCGCGACCTCAGCCAGCGCACCGAACGCACCGCCTCCCACCTGCAGGACGCAGC
GGCATCGATGGGCCAGCTGGACGGCGCCGTGCAGCACAGCGTGCAGGAGGCGGTGGCCGCCCGCCGGCTGACGCAGGAAG
CCACCCAGGTGGCGGAGCACTGCGGCGGCGTGGTGACCGAGGTCGTCGCCACCGTGCAGGACATCCACTCCAGCGCCGGA
CGCATTGCCGACATCGTGGGCGTGATCGATGGCATCGCCTTCCAGACGAACATCCTGGCGCTGAACGCCGCGGTGGAGGC
GGCCCGCGCCGGCGAACAGGGCCGGGGTTTCGCGGTGGTGGCGAGCGAGGTGCGCTCGCTGGCCGGACGCAGCGCCGAAG
CCGCCCGCGAAGTCCGCGCGCTCATCGCCGCCTCCGTGCAGAAGGCCGAGCGCGGCAGCCGGCTGGCGACGGATGCCGGC
GAGCACATGCAGAACGTGGTGGACTGCGCACGCCGTGCCTCCGAGGTGGTGGGCGCCATCAGCACATCGGTCGAAGGGCA
ATCGGGCGAACTGGGCCGCGTCAACGCCTCGGTGACCGAACTCGATCACATGACCCAGCAGAACGCGGCGCTGGTCGAGC
AGTCCTCGGCCGCGGCGGCCAGCCTGCTGGAGCAGGCCGGCCGGCTCAGGAGCGTGGTGGACGGCTTCCAGTTCCAGCCC
GAACGCCTGCTCGCCGCAGCGCGCTGA

Upstream 100 bases:

>100_bases
TGTATCCTTCTTTGCCTTTGGTTCTGTTCCGCGTCCTGCATCGGCGCCACGCTTTGCCGGCCCTCCCGCTCCACAGATAC
CACCCACCATCCGCCAGCCC

Downstream 100 bases:

>100_bases
ATTCATGCCGGAGCCGGCGCCGAAGGCCCGGAGCCCCGGCCCGGCCCGGCTCACGCGCCTTCGAGCTGCAGGTACACCTT
GCCCTGCTCGATCCGCACGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MGKAKRGRDLSPSAQQALQTIACRADALLLAICALGAIVALWIGFVYGRPGTAAIWGGALMALAAWAYLAVRGSLLGRLA
LVTAGIGLVALHIQLSLGATEMHFGVFVFLAFVLAYRDWRPVVFAAVLIAVHHIAFDRLQLAGGPVYCLTEPDFGRVLVH
AAFVVVQTAVEVAITLRTRADAIESAELQYLCRPQQDGQLSLDVRGVPVDSAAARALQAALLRLNGVVTDVHQAAAGLAA
AAGEIATGNRDLSQRTERTASHLQDAAASMGQLDGAVQHSVQEAVAARRLTQEATQVAEHCGGVVTEVVATVQDIHSSAG
RIADIVGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAGRSAEAAREVRALIAASVQKAERGSRLATDAG
EHMQNVVDCARRASEVVGAISTSVEGQSGELGRVNASVTELDHMTQQNAALVEQSSAAAASLLEQAGRLRSVVDGFQFQP
ERLLAAAR

Sequences:

>Translated_488_residues
MGKAKRGRDLSPSAQQALQTIACRADALLLAICALGAIVALWIGFVYGRPGTAAIWGGALMALAAWAYLAVRGSLLGRLA
LVTAGIGLVALHIQLSLGATEMHFGVFVFLAFVLAYRDWRPVVFAAVLIAVHHIAFDRLQLAGGPVYCLTEPDFGRVLVH
AAFVVVQTAVEVAITLRTRADAIESAELQYLCRPQQDGQLSLDVRGVPVDSAAARALQAALLRLNGVVTDVHQAAAGLAA
AAGEIATGNRDLSQRTERTASHLQDAAASMGQLDGAVQHSVQEAVAARRLTQEATQVAEHCGGVVTEVVATVQDIHSSAG
RIADIVGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAGRSAEAAREVRALIAASVQKAERGSRLATDAG
EHMQNVVDCARRASEVVGAISTSVEGQSGELGRVNASVTELDHMTQQNAALVEQSSAAAASLLEQAGRLRSVVDGFQFQP
ERLLAAAR
>Mature_487_residues
GKAKRGRDLSPSAQQALQTIACRADALLLAICALGAIVALWIGFVYGRPGTAAIWGGALMALAAWAYLAVRGSLLGRLAL
VTAGIGLVALHIQLSLGATEMHFGVFVFLAFVLAYRDWRPVVFAAVLIAVHHIAFDRLQLAGGPVYCLTEPDFGRVLVHA
AFVVVQTAVEVAITLRTRADAIESAELQYLCRPQQDGQLSLDVRGVPVDSAAARALQAALLRLNGVVTDVHQAAAGLAAA
AGEIATGNRDLSQRTERTASHLQDAAASMGQLDGAVQHSVQEAVAARRLTQEATQVAEHCGGVVTEVVATVQDIHSSAGR
IADIVGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAGRSAEAAREVRALIAASVQKAERGSRLATDAGE
HMQNVVDCARRASEVVGAISTSVEGQSGELGRVNASVTELDHMTQQNAALVEQSSAAAASLLEQAGRLRSVVDGFQFQPE
RLLAAAR

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=255, Percent_Identity=52.156862745098, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI2367378, Length=268, Percent_Identity=51.865671641791, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1787690, Length=275, Percent_Identity=46.1818181818182, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1788194, Length=260, Percent_Identity=45, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789453, Length=247, Percent_Identity=40.8906882591093, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 50881; Mature: 50749

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKAKRGRDLSPSAQQALQTIACRADALLLAICALGAIVALWIGFVYGRPGTAAIWGGAL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
MALAAWAYLAVRGSLLGRLALVTAGIGLVALHIQLSLGATEMHFGVFVFLAFVLAYRDWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCH
PVVFAAVLIAVHHIAFDRLQLAGGPVYCLTEPDFGRVLVHAAFVVVQTAVEVAITLRTRA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAIESAELQYLCRPQQDGQLSLDVRGVPVDSAAARALQAALLRLNGVVTDVHQAAAGLAA
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGEIATGNRDLSQRTERTASHLQDAAASMGQLDGAVQHSVQEAVAARRLTQEATQVAEH
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGGVVTEVVATVQDIHSSAGRIADIVGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ASEVRSLAGRSAEAAREVRALIAASVQKAERGSRLATDAGEHMQNVVDCARRASEVVGAI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
STSVEGQSGELGRVNASVTELDHMTQQNAALVEQSSAAAASLLEQAGRLRSVVDGFQFQP
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ERLLAAAR
HHHHHCCC
>Mature Secondary Structure 
GKAKRGRDLSPSAQQALQTIACRADALLLAICALGAIVALWIGFVYGRPGTAAIWGGAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
MALAAWAYLAVRGSLLGRLALVTAGIGLVALHIQLSLGATEMHFGVFVFLAFVLAYRDWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCH
PVVFAAVLIAVHHIAFDRLQLAGGPVYCLTEPDFGRVLVHAAFVVVQTAVEVAITLRTRA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAIESAELQYLCRPQQDGQLSLDVRGVPVDSAAARALQAALLRLNGVVTDVHQAAAGLAA
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGEIATGNRDLSQRTERTASHLQDAAASMGQLDGAVQHSVQEAVAARRLTQEATQVAEH
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGGVVTEVVATVQDIHSSAGRIADIVGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ASEVRSLAGRSAEAAREVRALIAASVQKAERGSRLATDAGEHMQNVVDCARRASEVVGAI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
STSVEGQSGELGRVNASVTELDHMTQQNAALVEQSSAAAASLLEQAGRLRSVVDGFQFQP
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ERLLAAAR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]