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The map label for this gene is nahR [H]

Identifier: 120608871

GI number: 120608871

Start: 182070

End: 183368

Strand: Reverse

Name: nahR [H]

Synonym: Aave_0163

Alternate gene names: 120608871

Gene position: 183368-182070 (Counterclockwise)

Preceding gene: 120608876

Following gene: 120608860

Centisome position: 3.43

GC content: 65.36

Gene sequence:

>1299_bases
ATGGAACTGGAAGACATCGACCTCAACCTGCTGGTGGTCTTCCAGCAACTGCTGGTCACGCGCAAGGTATCGCAGGCGGC
CGAGAACCTGGGCCTGACGCAGCCGGCCGTGAGCAATGCCCTCGCGCGGCTGCGGCGCCTGCTGGGCGACGAACTGTTCC
TGCGCACGGCCCATGGCATGCAGCCCACGCCCTACGCCGACCAGCTCGCGGAATCCGTGTCGTACGCGCTCGCGATGATC
CACGGCGCCCTGAACCACAAGCTGGGGTTCGACCCCGCCACCAGCCGGCGCGTGTTCAAGGTGGGCATGACGGACATCGG
CGAGATCTACTTCCTGCCCCGCCTGCTGGAGCGCCTGGCCCAGGTGGCGCCCGGCGTGCGCCTGGCCACCGTGCGCAATT
CAGCGACGGATCTGAAGGACGCCATGGAAGCCGGCAAGATCGACCTCGCCGTCGGCCTGCTGCCGCAATTGAAGGCCGGC
TTCTTCCAGCGCCGGCTGTTCCGCCAGCCCTACGTGTGCCTCTTCCGCCAGGGCCACCCGCTGCACAGGCGCCGCCGCAT
CGGGCTGGAGGATTTCGCGAAGGCGCAGCACGTGGTGGTCGTGTCCGAAGGCACGGGCCACGGCAAGGTGGACGAACTGC
TCGAGCGCATGGGCGTGGCCCGCGACGTGCGCCTCACCGTGCCGCACTTCGTCGCCATCGGCCACATCCTCCAGGCCACC
CGGATGATCGCCACCGTGCCCGAGAAGATGGCCCAGAGCATGGCCGGGCCCTTCGGCCTGGCGTATGCGCCCCACCCCGT
CAAATTGCCGCAGGTGGCGATCAATCTGTTCTGGCACACGAAGTACCACCGGGATCCGGGGAACCAGTGGTTGCGGGGGT
GGTGGTGGAGATGTTTGCGGAGGGGGAGTGAGGGGGCACGGCGGCCCCGTCGTTCGGCCTTCGGAATTCGGGATTTGGAA
GCTATTGCGGCGCTACTTTTTCCATCAAGCACGGGGCACGTAGCAATGTCGCCTATAGGCTGGTTGCGGTCGTTCATTTT
TGAATACGGACGATCGCTGTCTCTGAAACCTGCCAGACGTGATTCAAAGGCTCCGTGGTCCGCAGTGCGCCAGTCACTGT
CGATCGCCTTGGGGACCTGCCCGGCGGCAGTGCGGCGTAACGGGCTACTGCAAGTCTGTCGCATTGCTGTCACAAGCACG
AAGTCGGTCGGGTCGAGACGATTGCCACTAGCTTGGGGGCATTCTCTCGAGACGCCGTCCTCTTACCCATTGACCAGACC
AGGGCAGACGGTCAGTTGA

Upstream 100 bases:

>100_bases
TCCAGGTTTTCGTTATGGCCCCGATCATTCCCGCGATTGTTTCATCAGCCAATAGAATGGCATGAATACTCAGCATTAAT
GGCTTGAATAAAGGTTCGTC

Downstream 100 bases:

>100_bases
CCGTCTGCAGCACATCATCCAAGGACCTCGCGACTAAGTAGCGCGCCGGGTTCTCGCCGGTCGCCAGTGCTGCGAAGTGC
GCTCGGCCGCACTCGATCTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MELEDIDLNLLVVFQQLLVTRKVSQAAENLGLTQPAVSNALARLRRLLGDELFLRTAHGMQPTPYADQLAESVSYALAMI
HGALNHKLGFDPATSRRVFKVGMTDIGEIYFLPRLLERLAQVAPGVRLATVRNSATDLKDAMEAGKIDLAVGLLPQLKAG
FFQRRLFRQPYVCLFRQGHPLHRRRRIGLEDFAKAQHVVVVSEGTGHGKVDELLERMGVARDVRLTVPHFVAIGHILQAT
RMIATVPEKMAQSMAGPFGLAYAPHPVKLPQVAINLFWHTKYHRDPGNQWLRGWWWRCLRRGSEGARRPRRSAFGIRDLE
AIAALLFPSSTGHVAMSPIGWLRSFIFEYGRSLSLKPARRDSKAPWSAVRQSLSIALGTCPAAVRRNGLLQVCRIAVTST
KSVGSRRLPLAWGHSLETPSSYPLTRPGQTVS

Sequences:

>Translated_432_residues
MELEDIDLNLLVVFQQLLVTRKVSQAAENLGLTQPAVSNALARLRRLLGDELFLRTAHGMQPTPYADQLAESVSYALAMI
HGALNHKLGFDPATSRRVFKVGMTDIGEIYFLPRLLERLAQVAPGVRLATVRNSATDLKDAMEAGKIDLAVGLLPQLKAG
FFQRRLFRQPYVCLFRQGHPLHRRRRIGLEDFAKAQHVVVVSEGTGHGKVDELLERMGVARDVRLTVPHFVAIGHILQAT
RMIATVPEKMAQSMAGPFGLAYAPHPVKLPQVAINLFWHTKYHRDPGNQWLRGWWWRCLRRGSEGARRPRRSAFGIRDLE
AIAALLFPSSTGHVAMSPIGWLRSFIFEYGRSLSLKPARRDSKAPWSAVRQSLSIALGTCPAAVRRNGLLQVCRIAVTST
KSVGSRRLPLAWGHSLETPSSYPLTRPGQTVS
>Mature_432_residues
MELEDIDLNLLVVFQQLLVTRKVSQAAENLGLTQPAVSNALARLRRLLGDELFLRTAHGMQPTPYADQLAESVSYALAMI
HGALNHKLGFDPATSRRVFKVGMTDIGEIYFLPRLLERLAQVAPGVRLATVRNSATDLKDAMEAGKIDLAVGLLPQLKAG
FFQRRLFRQPYVCLFRQGHPLHRRRRIGLEDFAKAQHVVVVSEGTGHGKVDELLERMGVARDVRLTVPHFVAIGHILQAT
RMIATVPEKMAQSMAGPFGLAYAPHPVKLPQVAINLFWHTKYHRDPGNQWLRGWWWRCLRRGSEGARRPRRSAFGIRDLE
AIAALLFPSSTGHVAMSPIGWLRSFIFEYGRSLSLKPARRDSKAPWSAVRQSLSIALGTCPAAVRRNGLLQVCRIAVTST
KSVGSRRLPLAWGHSLETPSSYPLTRPGQTVS

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=27.0903010033445, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87081766, Length=290, Percent_Identity=25.5172413793103, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790147, Length=298, Percent_Identity=23.1543624161074, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789204, Length=224, Percent_Identity=26.3392857142857, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 48082; Mature: 48082

Theoretical pI: Translated: 11.32; Mature: 11.32

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEDIDLNLLVVFQQLLVTRKVSQAAENLGLTQPAVSNALARLRRLLGDELFLRTAHGM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QPTPYADQLAESVSYALAMIHGALNHKLGFDPATSRRVFKVGMTDIGEIYFLPRLLERLA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
QVAPGVRLATVRNSATDLKDAMEAGKIDLAVGLLPQLKAGFFQRRLFRQPYVCLFRQGHP
HHCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
LHRRRRIGLEDFAKAQHVVVVSEGTGHGKVDELLERMGVARDVRLTVPHFVAIGHILQAT
HHHHHCCCHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHH
RMIATVPEKMAQSMAGPFGLAYAPHPVKLPQVAINLFWHTKYHRDPGNQWLRGWWWRCLR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RGSEGARRPRRSAFGIRDLEAIAALLFPSSTGHVAMSPIGWLRSFIFEYGRSLSLKPARR
CCCHHHCCCHHHHCCCHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCCCC
DSKAPWSAVRQSLSIALGTCPAAVRRNGLLQVCRIAVTSTKSVGSRRLPLAWGHSLETPS
CCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCC
SYPLTRPGQTVS
CCCCCCCCCCCC
>Mature Secondary Structure
MELEDIDLNLLVVFQQLLVTRKVSQAAENLGLTQPAVSNALARLRRLLGDELFLRTAHGM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QPTPYADQLAESVSYALAMIHGALNHKLGFDPATSRRVFKVGMTDIGEIYFLPRLLERLA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
QVAPGVRLATVRNSATDLKDAMEAGKIDLAVGLLPQLKAGFFQRRLFRQPYVCLFRQGHP
HHCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
LHRRRRIGLEDFAKAQHVVVVSEGTGHGKVDELLERMGVARDVRLTVPHFVAIGHILQAT
HHHHHCCCHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHH
RMIATVPEKMAQSMAGPFGLAYAPHPVKLPQVAINLFWHTKYHRDPGNQWLRGWWWRCLR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RGSEGARRPRRSAFGIRDLEAIAALLFPSSTGHVAMSPIGWLRSFIFEYGRSLSLKPARR
CCCHHHCCCHHHHCCCHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCCCC
DSKAPWSAVRQSLSIALGTCPAAVRRNGLLQVCRIAVTSTKSVGSRRLPLAWGHSLETPS
CCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCC
SYPLTRPGQTVS
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]